Clinical trials: Post Traumatic Stress
Posttraumatic Stress Disorders, PTSD
An Online CBT, Mindfulness Meditation & Yoga (CBT-MY) Intervention for Posttraumatic Stress Disorder
Post-traumatic stress disorder (PTSD), a chronic, debilitating condition, is a growing public health concern as the Canadian population has the highest PTSD prevalence worldwide (9.2%; 3.7 million people).
- Trial name
- NCT03684473
- Testing
- Online Mindfulness-Based CBT & Trauma-Informed Yoga Intervention
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- York University
Stress Disorders, Post-Traumatic
Risperidone Treatment for Military Service Related Chronic Post Traumatic Stress Disorder
The purpose of this research of 400 participants is to determine whether a drug called risperidone can decrease symptoms of Post-Traumatic Stress Disorder (PTSD).
- Trial name
- CSP #504 (NCT00099983)
- Testing
- Risperidone
- Where
- 20 sites in United States
- Volunteers
- 296 people
- Sponsor
- US Department of Veterans Affairs
Depressive Symptoms, Emotional Depression
Parenting-STAIR Modular for Military Fathers and OCONUS Families
The goal of this clinical trial is to learn if a family-based treatment called Parenting-STAIR-Modular (PSTAIR-M) can help military parents recover from trauma, strengthen emotion regulation skills, and improve parent-child…
- Conditions
- Depressive Symptoms, Emotional Depression, Depression, Parent Child Relationship
- Trial name
- NCT07843654
- Testing
- Parenting-STAIR Modular (PSTAIR-M), Treatment as Usual (TAU)
- Where
- 6 sites in United States, South Korea
- Volunteers
- 243 people
- Sponsor
- New York University
Amputation, PTSD
Evacuation Time and Tourniquet Use as Risk Factors for PTSD in Combat-Related Amputation
This study aims to evaluate the relationship between evacuation time, tourniquet use, and the development of post-traumatic stress disorder (PTSD) in patients with combat-related amputations.
- Conditions
- Amputation, PTSD, Combat Posttraumatic Stess Disorder, Combat Trauma
- Trial name
- EVAC-PTSD Stud (NCT07502313)
- Where
- Ukraine
- Volunteers
- 300 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Alcohol Use Disorder, Posttraumatic Stress Disorder
Mobile Mindfulness for Alcohol Use and PTSD Among Veterans
The purpose of the present study is to develop and test a mobile mindfulness intervention for Alcohol Use Disorder and PTSD among OEF/OIF veterans
- Trial name
- NCT04769986
- Testing
- Mobile Mindfulness-Relapse Prevention (mMBRP), Exercise/healthy eating mobile app
- Where
- 3 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Physical Activity, Sedentary Behavior
Exploring Virtual Reality Adventure Training Exergaming
The current project aims to design and implement an 8-week Virtual Reality Adventure Therapy Exergaming (V-RATE) intervention focused on women veterans.
- Conditions
- Physical Activity, Sedentary Behavior, Depression, Cognitive Function
- Trial name
- V-RATE (NCT05563805)
- Testing
- Virtual Reality-based physical activity intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Posttraumatic Stress Disorder, Burns
Early Intervention to Prevent Development of PTSD in Burn Survivors and Their Caregivers
The purpose of this clinical trial is to adapt and test a brief patient-caregiver early intervention designed to reduce posttraumatic stress symptoms in hospitalized burn patients and their caregivers.
- Conditions
- Posttraumatic Stress Disorder, Burns, Traumatic Injury, Acute Stress Disorder
- Trial name
- NCT07656545
- Testing
- Promotion of Emotional Disclosure for Burns (PoED-B), minimally Enhanced Usual Care control (mEUC)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Post-Traumatic Stress Disorder
Effect of Propranolol on Preventing Posttraumatic Stress Disorder
This study will assess the effectiveness of taking propranolol soon after a traumatizing incident in reducing the incidence and severity of posttraumatic stress disorder in acutely traumatized individuals.
- Trial name
- NCT00158262
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Post-traumatic Stress Disorder, Stress Disorders
Effectiveness of Cognitive Processing Therapy in Pregnant Women With a History of Pregnancy Loss/Complication
The purpose of this study is to examine the effects of experiencing a previous pregnancy loss or complication on current physiological and emotional aspects of a current pregnancy.
- Conditions
- Post-traumatic Stress Disorder, Stress Disorders, Anxiety, Depression
- Trial name
- NCT01277354
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Pennsylvania
Posttraumatic Stress Disorder (PTSD)
Oxytocin and Affect Processing in Posttraumatic Stress Disorder
The investigators will use multiple methods (including Oxytocin intranasal inhalation, neuroimaging, behavioral measures, peripheral hormone measurements) to examine how individuals' behavior, cognition, and brain function is…
- Trial name
- NCT02546570
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Yale University
Depression, PTSD
The Efficacy of an Exercise Program and a Yoga Program in Mitigating Stress and Improving Mental Health Among Employees
To reduce workplace stress and promote mental health, participants were divided into three groups: exercise program, yoga program, and self-care.
- Conditions
- Depression, PTSD, Work Related Stress
- Trial name
- NCT06620783
- Testing
- exercise, yoga, active self-care
- Where
- 2 sites in South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Violence, Sexual, Violence, Physical
Online Psychosocial Intervention for Nursing Students Who Experienced Intimate Partner Abuse in Turkey
Intimate partner abuse is very common among university students. Post-traumatic stress disorder is one of the most serious mental diseases caused by intimate partner abuse.The purpose of this study was to assess the impact of an…
- Conditions
- Violence, Sexual, Violence, Physical, Violence, Gender-Based, Violence
- Trial name
- NCT05368779
- Testing
- The internet-based psychosocial intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Bozok University
Post Traumatic Stress Disorder PTSD
EMDR vs. CBT for PTSD
This study compares two evidence-based therapies, Eye Movement Desensitization and Reprocessing (EMDR) and Cognitive Behavioral Therapy (CBT), in reducing symptoms of post-traumatic stress disorder (PTSD) among adults affected by…
- Trial name
- EARTH-PTSD (NCT06758362)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR), Cognitive Behavioral Therapy (CBT)
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Istanbul Nisantasi University
Traumatic Brain Injury, Post-Traumatic Stress Disorder
Executive Functioning in TBI From Rehabilitation to Social Reintegration: COMPASS
Interventional, controlled clinical trial with two arms, 110 Veterans with TBI and PTSD
- Trial name
- COMPASS (NCT01816061)
- Testing
- Experimental - COMPASS, Control - COMPASS
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
HIV, AIDS
Intervention Program to Address PTSD in People Living With HIV
The goal of this randomised controlled trial is to evaluate the efficacy of an integrated intervention program on post-traumatic stress disorder (PTSD) symptoms and related physiological and psychological indicators of people…
- Conditions
- HIV, AIDS, Mindfulness-based Stress Reduction, China
- Trial name
- NCT05588596
- Testing
- Trauma Resiliency Mindfulness-Informed Intervention
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Central South University
Cognitive Behavioral Therapy
Cognitive Behavioral Therapy for Post-Traumatic Stress Disorder
The current study is designed to measure the role of cognitive behavior therapy with PTSD patients. There are following objectives of this current study, such as 1.
- Trial name
- NCT06177223
- Testing
- Cognitive Behavioral therapy
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Government College University Faisalabad
Post-Traumatic Stress Disorder, Adjustment Disorders
MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers and First Responders
The purpose of this study is to assess the safety and efficacy of MDMA-Assisted Therapy on Frontline Health Care Workers and First Responders suffering from symptoms of Post-Traumatic Stress.
- Trial name
- NCT05455996
- Testing
- MDMA
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Nautilus Sanctuary
Post-Traumatic Stress Disorder
Brain Receptor Function in Post-Traumatic Stress Disorder
The purpose of this study is to examine the function of cortisol receptors in post-traumatic stress disorder (PTSD). Patients with PTSD have neurobiological dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis function.
- Trial name
- NCT00046553
- Testing
- RU-486 (Mifepristone)
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Posttraumatic Stress Disorder (PTSD), Borderline Personality Disorder (BPD)
Effectiveness of PTSD-treatment Compared to Integrated PTSD-PD-treatment in Adult Patients With Comorbid PTSD and BPD
The goal of PROSPER-B is to study effectiveness of EMDR compared to integrated DBT-EMDR in treatment-seeking, adult patients with comorbid PTSD and Borderline Personality Disorder (BPD).
- Trial name
- PROSPER-B (NCT03833453)
- Testing
- EMDR, DBT
- Where
- Netherlands
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Arkin
Convulsion, Non-Epileptic, Conversion Disorder
Treatment Trial for Psychogenic Nonepileptic Seizures
The investigators propose that patients who receive targeted pharmacotherapy (sertraline) or focused psychotherapy (cognitive behavioral therapy-informed psychotherapy (CBT-ip) for NES) or combined treatment (CBT-ip + sertraline)…
- Conditions
- Convulsion, Non-Epileptic, Conversion Disorder, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NEST-T_1 (NCT00835627)
- Testing
- sertraline, CBT-ip, Combined (sertraline + CBT-ip)
- Where
- 3 sites in United States
- Volunteers
- 38 people
- Sponsor
- Rhode Island Hospital
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