Clinical trials: Post Traumatic Stress
Alcohol Use Disorder, Posttraumatic Stress Disorder
Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship
Intimate partner violence (IPV) is a serious public health problem that results in significant health and economic burdens including mortality, morbidity, and poor treatment outcomes.
- Conditions
- Alcohol Use Disorder, Posttraumatic Stress Disorder, Couples
- Trial name
- NCT05786157
- Testing
- Alcohol Administration
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Medical University of South Carolina
PTSD, Depression
Synchronized Transcranial Magnetic Stimulation for PTSD
The investigators propose a small, two-site, sham-controlled pilot study of synchronized Transcranial Magnetic Stimulation (sTMS) in patients with comorbid post-traumatic stress disorder (PTSD) and depression.
- Trial name
- sTMS (NCT02981381)
- Testing
- NEST-1, NEST-2
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Providence VA Medical Center
Adult ALL, Post-traumatic Stress Disorder
Effects of an EMDR Intervention on Traumatic and Obsessive Symptoms
The Eye Movement Desensitization and Reprocessing Protocol (EMDR) was first developed by Francine Shapiro in 1987 and can be adapted for online and in presence administration.
- Conditions
- Adult ALL, Post-traumatic Stress Disorder, Obsessive-Compulsive Disorder, Disgust
- Trial name
- MDL (NCT06110702)
- Testing
- EMDR
- Where
- Italy
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Domestic Violence, Depression
Cortisol Evaluation in Abuse Survivors
This study looks at the biological effect of domestic violence and abuse (DVA) on women's mental health. The mechanisms through which DVA causes mental disorders are very poorly understood.
- Conditions
- Domestic Violence, Depression, Anxiety, Panic Disorder
- Trial name
- CEASE (NCT01632553)
- Where
- 2 sites in United Kingdom
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Borderline Personality Disorder, Post-Traumatic Stress Disorders
Outcome of Crisis Intervention for Subjects With Borderline Personality Disorder or Post-Traumatic Stress Disorder
Dr. Laddis will test a hypothesis about the nature and the management of behavioral crises in patients with borderline personality disorder (BPD) or post-traumatic stress disorder (PTSD).
- Trial name
- NCT00269139
- Testing
- Crisis resolution
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Laddis, Andreas, M.D.
PTSD, Chronic Musculoskeletal Pain
Mission Reconnect-Veterans and Their Partners to Manage Pain and PTSD (MR)
This project is responsive to Rehabilitation Research and Development's (RR\&D) current special areas of interest for non-pharmacological activity-based interventions for chronic pain impacting pain reduction, function and…
- Trial name
- MR (NCT03593772)
- Testing
- Mission Reconnect
- Where
- 3 sites in United States
- Volunteers
- 730 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Testing the Efficacy of a Mindfulness- and Acceptance-Based Smartphone App for PTSD: A Randomized Controlled Trial
The purpose of the study is to test the feasibility and acceptability of a mindfulness- and acceptance-based smartphone app (MABSA) intervention for college student veterans with posttraumatic stress disorder (PTSD) symptoms.
- Trial name
- NCT04861311
- Testing
- Mindfulness/Acceptance-Based Smartphone App (MABSA) Intervention
- Volunteers
- 64 people
- Sponsor
- University of Nevada, Las Vegas
Posttraumatic Stress Disorder, Insomnia
Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder
This pilot pre-post trial will address a gap in knowledge related to addressing modifiable risk factors for cardiometabolic disease through treating residual insomnia, sleep difficulties that remain after successful treatment of…
- Conditions
- Posttraumatic Stress Disorder, Insomnia, Cardiovascular Diseases, Metabolic Disease
- Trial name
- NCT05516277
- Testing
- Behavioral Sleep Education Intervention
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Post Traumatic Stress Disorder
A Multi-site Expanded Access Program for MDMA-assisted Psychotherapy for Patients With Treatment-resistant PTSD
The goal of this expanded access protocol is to provide access to MDMA-assisted therapy for eligible patients with treatment-resistant PTSD who are not able to enroll in another MDMA-assisted therapy clinical trial.
- Trial name
- EAMP1 (NCT04438512)
- Testing
- Midomafetamine, Psychotherapy
- Where
- 2 sites in United States
- Sponsor
- Resilient Pharmaceuticals
Posttraumatic Stress Disorder
Telemental Health and Cognitive Processing Therapy for Female Veterans With Military-related PTSD
The immediate objective of this project is to evaluate the clinical effectiveness of a telemental health modality (video-teleconferencing) for providing an evidence-based group intervention to female rural veterans, Reservists…
- Trial name
- NCT02362477
- Testing
- Cognitive Processing Therapy in-person, Cognitive Processing Therapy through videoteleconference
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- VA Pacific Islands Health Care System
Post-traumatic Stress Disorder, Adjustment Disorders
Pivotal Trial of SAT-014 for Trauma and Stressor-Related Disorder Symptoms
The aim of this study is to evaluate the efficacy of SAt-014, a software as a medical device (SaMD), in alleviating symptoms of trauma and stressor-related disorders in patients with post-traumatic stress disorder (PTSD) or…
- Trial name
- NCT06734858
- Testing
- SAT014, Control
- Where
- 5 sites in South Korea
- Volunteers
- 110 people
- Sponsor
- S-Alpha Therapeutics, Inc.
Post-Traumatic Stress Disorder
Prolonged Exposure Therapy Versus Active Psychotherapy in Treating Post-Traumatic Stress Disorder in Adolescents
This study will compare the effectiveness of prolonged exposure therapy versus active psychotherapy in treating post-traumatic stress disorder (PTSD) in adolescents.
- Trial name
- NCT00183690
- Testing
- Prolonged Exposure Therapy, Active Psychotherapy
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Mental Disorders, Psychological Trauma
Hospital Cohort Survey of Public Health Post-attack of July 14, 2016
The terrorist attack on the ram truck, which occurred on 14 July 2016 on the Promenade des Anglais in Nice, involved a significant number of casualties in the civilian population: 86 dead including 10 children and adolescents…
- Trial name
- ECHOS (NCT03353805)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Post-Traumatic Neck Pain, Whiplash-associated Disorders
StressModex for Post-Traumatic Neck Pain
Post-traumatic neck pain is a common consequence of traffic-related and other accidental injuries. While many individuals recover, a subgroup develops persistent pain, disability, and psychological distress.
- Trial name
- StressModex (NCT07824557)
- Testing
- StressModex plus Treatment as Usual
- Where
- 3 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- University of Southern Denmark
Post Traumatic Stress Disorder, Obstructive Sleep Apnea
OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit
Substance use disorder (SUD) and posttraumatic stress disorder (PTSD) frequently co-occur and having both disorders is associated with greater psychological and functional impairment than having either disorder alone.
- Conditions
- Post Traumatic Stress Disorder, Obstructive Sleep Apnea, Substance Use Disorder, Residential Treatment Program
- Trial name
- NCT05156112
- Testing
- Positive Airway Pressure Device
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- VA Office of Research and Development
Domestic Violence, Post-Traumatic Stress Disorder
Mental Health Symptoms and Intimate Partner Violence
Using a touch screen computer, the researchers are screening emergency department patients for intimate partner violence and mental health issues.
- Conditions
- Domestic Violence, Post-Traumatic Stress Disorder, Depression
- Trial name
- NCT00166075
- Testing
- Computer screen with community resource printout
- Where
- United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Emory University
Insomnia, Nightmares
Initial Study of Insomnia/Nightmare Group Treatment for Posttraumatic Stress Disorder (PTSD)
Many combat Veterans suffer from posttraumatic stress disorder (PTSD), an anxiety disorder that develops after an extremely stressful event or events. PTSD is associated with problems falling asleep or staying asleep.
- Conditions
- Insomnia, Nightmares, Posttraumatic Stress Disorder
- Trial name
- NCT01314612
- Testing
- Cognitive-Behavioral Insomnia and Nightmare Group
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michael E. DeBakey VA Medical Center
Stress Disorders, Post-Traumatic, Intimate Partner Violence
Addressing the Health Concerns of VA Women With Sexual Trauma
Lifetime sexual trauma (ST) (i.e., behaviors that range from unwanted sexual touching to attempted or completed rape) is a significant social and public health problem among women Veterans.
- Conditions
- Stress Disorders, Post-Traumatic, Intimate Partner Violence, Alcohol-Related Disorders
- Trial name
- SHE (NCT02957747)
- Testing
- SHE
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- VISN 17 Center of Excellence
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Concurrent Treatment for Substance Dependent Individuals With Post-Traumatic Stress Disorder (PTSD)
This treatment intervention trial is designed for men and women with substance dependence and comorbid Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT01365247
- Testing
- Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure, Relapse Prevention Treatment, Active Monitoring Control Group
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- The City College of New York
Covid-19, Family Members
Impact of Covid-19 Restrictive Measure on Anxiety, Depression and PTSD for Relatives of ICU Patients
To limit the pandemic Covid-19 infection, the French government imposed a closure of all Intensive Care Unit (ICU). The family's visitations are prohibited during active Covid -19 pandemic in 2020 and in 2021.
- Conditions
- Covid-19, Family Members, Critical Illness
- Trial name
- HAD-Covid (NCT04430049)
- Testing
- Covid ICU containment measures
- Where
- 11 sites in France
- Volunteers
- 811 people
- Sponsor
- University Hospital, Clermont-Ferrand
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