Clinical trials: Post Traumatic Stress
PTSD, Trauma-related Mental Health Symptoms
Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series
This study prospectively evaluates the effects of Integrative Bilateral Cervical Sympathetic Block (BCSB) on trauma-related symptoms in Special Operations Veterans, comparing outcomes in those receiving BCSB alone versus BCSB…
- Conditions
- PTSD, Trauma-related Mental Health Symptoms, Moral Injury, Anxiety
- Trial name
- NCT07473505
- Testing
- stellate ganglion block with 0.5% ropivacaine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Reset Medical and Wellness Center
Insomnia, Posttraumatic Stress Disorder
Suvorexant and Trauma Related Insomnia
Problems sleeping are common after exposure to highly threatening experiences and can occur with and without a diagnosis of posttraumatic stress disorder (PTSD).
- Trial name
- NCT02704754
- Testing
- suvorexant
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Howard University
Military Spouses, Support Groups
Reintegration: The Role of Spouse Telephone BATTLEMIND Pilot Study
This study will expand the Department of Defense (DoD) one time, face-to-face post deployment BATTLEMIND training for spouses of Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Guard/Reserve service members into…
- Conditions
- Military Spouses, Support Groups, Stress Disorders, Combat Disorders
- Trial name
- NCT00870545
- Testing
- Telephone support groups
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Memphis VA Medical Center
Posttraumatic Stress Disorder
A Controlled Breathing Course for Social & Emotional Health for Vietnam Veterans With Chronic PTSD-RCT
The main aim of this project is to evaluate the use of a specific Yoga technique of controlled breathing in Vietnam War Veterans with chronic posttraumatic stress disorder.
- Trial name
- NCT00256477
- Testing
- Sudarshan KRIYA Breathing Technique
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Type 1 Diabetes
Prevalence of Post Traumatic Stress Disorder Related to Diabetes Diagnosis or Severe Hypoglycaemia in Adult With Type 1 Diabetes
In France, the adult population living with diabetes in 2016 is estimated at more than 3.3 million patients treated. Type 1 diabetes (T1DM) represents 5.6% of diabetic patients (approximately 185,000 patients).
- Trial name
- NCT05662657
- Testing
- Diagnostic Test: PCL-S Questionnaire
- Where
- 2 sites in France
- Volunteers
- 297 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Impulsive Aggression, Posttraumatic Stress Disorder
Pilot Trial of Neural Correlates of Response to Treatment of PTSD-Associated Impulsive Aggression
The purpose of this study is to identify changes in brain functioning which are related to reduced frequency and/or intensity of impulsive aggressive actions after treatment of PTSD-related impulsive aggression with either…
- Trial name
- NCT00333931
- Testing
- Phenytoin, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Michael E. DeBakey VA Medical Center
Stress Disorders, Post Traumatic, Brain Injuries
Mind-Body Skills Groups for the Treatment of War Zone Stress in Military and Veteran Populations
The purpose of this study is to determine whether participation in mind-body skills groups by veterans who have experienced a stressful war-related situation and have symptoms of posttraumatic stress disorder (PTSD), will improve…
- Conditions
- Stress Disorders, Post Traumatic, Brain Injuries, Depressive Disorder, Anxiety Disorders
- Trial name
- NCT01093053
- Testing
- Mind-Body Skills Groups, Standard Treatment
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Center for Mind-Body Medicine
Complex Post-Traumatic Stress Disorder
Context Sensitivity in Emotion Regulation in Post-Traumatic Stress Disorder
This study will examine context sensitivity, composed of two sequential elements: (a) accurate classification of changing affective contextual demands, followed by (b) flexible selection of regulatory strategies that matches…
- Trial name
- NCT06007612
- Testing
- Context Sensitivity in Emotion Regulation
- Where
- Israel
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Gal Sheppes
PTSD
Psychological and Physiological Status of Former Prisoners of War
Assessing the psychological and physiological status of Israeli former prisoners of war (POW).
- Trial name
- NCT00294957
- Where
- Israel
- Sponsor
- Sheba Medical Center
Post Traumatic Stress Disorder, Opioid-use Disorder
Lofexidine Combined With Buprenorphine for Reducing Symptoms of PTSD and OU Relapse in Veterans
The overall objective of the proposed study is to determine if lofexidine (LFX) as an adjunct to buprenorphine (BUP) treatment improves symptoms of both opioid use disorder (OUD) and Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT04360681
- Testing
- Lofexidine
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Posttraumatic Stress Disorder
Trial of Mifepristone in Combat Veterans With Posttraumatic Stress Disorder
The investigators propose to conduct a randomized double-blind, parallel-group, placebo-controlled trial of mifepristone in veterans with military-related posttraumatic stress disorder (PTSD).
- Trial name
- NCT00833339
- Testing
- mifepristone
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Alzheimer's Disease, Mild Cognitive Impairment
Retinal Imaging in Neurodegenerative Disease
This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus photography to assess the structure and function of the…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple Sclerosis
- Trial name
- NCT03233646
- Testing
- Retinal and Choroidal Imaging
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Traumatic Brain Injury (TBI) Patients
Transcutaneous Vagus Nerve Stimulation for Attention and Memory
This clinical trial aims to evaluate whether transcutaneous auricular vagus nerve stimulation (taVNS), a non-invasive brain stimulation method, can improve attention and memory in veterans with traumatic brain injury (TBI) and…
- Trial name
- taVNS (NCT06723743)
- Testing
- Transcutaneous vagus nerve stimulation for attention in veterans with TBI, Soterix Medical Vagus Nerve Stimulation mini-CT
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
PTSD, Anxiety Disorders
Creating Resilient Workplaces Study
The proposed study aims to understand the impact of a 5-Class CBTm Course on variables contributing to workplace resilience among Public Safety Personnel (PSP).
- Conditions
- PTSD, Anxiety Disorders, Depression, Stress Disorders, Posttraumatic
- Trial name
- CReW (NCT04002050)
- Testing
- Cognitive Behavioural Therapy with Mindfulness Course
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Organ Donation, Next of Kin
Bernese Next of Kin Survey Following Organ Donation Request
6 to 18 months after organ donation request a next of kin survey using a standardized questionnaire was conducted.
- Conditions
- Organ Donation, Next of Kin, Post Traumatic Stress Disorder
- Trial name
- NCT03612024
- Testing
- questionnaire
- Where
- Switzerland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Mental Health, Stress Disorder, Post Traumatic
Psychological Stress and Support Needs of Volunteer First Responders After Smartphone-based Cardiac Arrest Alerts
Out-of-hospital cardiac arrest is a serious emergency. In many areas, trained volunteers are alerted by a smartphone app to help before emergency services arrive.
- Trial name
- BRAVE (NCT07607808)
- Testing
- Structured Debriefing
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospital, Aachen
PTSD, Post Traumatic Stress Disorder PTSD
Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)
The goal of this clinical trial is to evaluate the safety and effectiveness of the gammaCore non-invasive vagus nerve stimulation (nVNS) device as an additional treatment for symptoms of post-traumatic stress disorder (PTSD) in…
- Conditions
- PTSD, Post Traumatic Stress Disorder PTSD, PTSD - Post Traumatic Stress Disorder, Post Traumatic Stress Disorder
- Trial name
- NCT07523685
- Testing
- non-invasive vagus nerve stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Acacia Clinics
Posttraumatic Stress Disorder
Group Cognitive Processing Therapy for Combat-related Posttraumatic Stress Disorder (PTSD)
The purpose of this study is to compare group-administered Cognitive Processing Therapy-Cognitive-only version (CPT-C), an evidence based treatment for posttraumatic stress disorder (PTSD), to Present Centered Therapy (PCT) in…
- Trial name
- NCT01286415
- Testing
- Group Cognitive Processing Therapy-Cognitive Only, Group Present Centered Therapy
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- VA Boston Healthcare System
Uterine Cervical Neoplasms
Post-TRaUmatic STress Disorder Induced by Gynecological Brachytherapy
This is a multicenter, prospective study aimed at providing information on the psychological effects (including post-traumatic stress symptoms) of utero-vaginal brachytherapy in patients with cervical cancer using…
- Trial name
- TRUST-GB (NCT07204535)
- Testing
- Prospective questionnaires
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Paul Strauss
Post-traumatic Stress Disorder (PTSD)
Transcranial Infrared Laser Stimulation (TILS) of Prefrontal Cognition in Post-traumatic Stress Disorder (PTSD)
This study evaluates the effects of transcranial infrared laser stimulation (TILS) on prefrontal metabolism and hemodynamics in veterans with post-traumatic stress disorder (PTSD).
- Trial name
- NCT03209882
- Testing
- TILS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas at Arlington
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