Clinical trials: Post-Abortion
Abortion Induced Complicated
Management of RPOC After Induced Abortion
Randomized trial comparing expectant management and medical management in women diagnosed with retained products of conception after first trimester induced abortion
- Trial name
- RPOC (NCT04685694)
- Testing
- Misoprostol
- Where
- Israel
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Unintended Pregnancy, Undesired Pregnancy
Attitudes and Decision-making After Pregnancy Testing Study
The ADAPT Study is a longitudinal observational cohort study examining women's pregnancy preferences, pregnancy decision-making processes, and the effects of less preferred (commonly called "unintended") pregnancy on women's…
- Trial name
- ADAPT (NCT03888404)
- Testing
- Pregnancy preferences (Aim 1), Sociocultural environment (Aim 2), Pregnancy preferences (Aim 3a)
- Where
- United States
- Volunteers
- 2,015 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Habitual Abortion, Recurrent Pregnancy Loss
Intravenous Immunoglobulin and Prednisolone for RPL After ART.
Recurrent pregnancy loss (RPL) affects around 5 % of women in reproductive age. The underlying cause of RPL is most often unknown, probably multifactorial, and no treatment with documented effect on chance of live birth exists.
- Conditions
- Habitual Abortion, Recurrent Pregnancy Loss, Fertility Disorders, Miscarriage
- Trial name
- RPL (NCT04701034)
- Testing
- Human Intravenous Immunoglobulins, (Privigen (R), CLS Behring), Prednisolone Tablets, Human Albumin Solution
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Aalborg University Hospital
Retained Products After Miscarriage
The HYsteroscopic Miscarriage MaNagement Trial: A Pilot RCT Investigating a Novel Management Pathway for RPOC
Pregnancy tissue can be found remaining in the womb in up to 20% of women following a miscarriage. These "retained products of conception" (RPOC), which are diagnosed by transvaginal ultrasound, can cause prolonged bleeding…
- Trial name
- HYMMN (NCT04751500)
- Testing
- Outpatient hysteroscopy, Expectant management, Medical management
- Where
- United Kingdom
- Volunteers
- 149 people
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Abortion
The Vaginal Progesterone and Cerclage
Pregnancy loss in the second trimester is not uncommon. About 2-3% of pregnancies will be lost in the second trimester, which is much lower than in the first trimester.
- Trial name
- NCT02846909
- Testing
- Progesterone
- Where
- Egypt
- Volunteers
- 242 people
- Sponsor
- Assiut University
Abortion, Induced
Postoperative Pain After Medical Abortion Under Local Anesthesia : Comparison of Several Analgesic Regimen
To compare postoperative analgesia by paracetamol 1gr or ketoprofen 100 mg or the combination of these two analgesics each treatment beeing allocated by randomization
- Trial name
- NCT00188071
- Testing
- paracetamol, ketoprofen, ketoprofen + paracetamol
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Angers
Retained Products of Conception Post Abortion
Oral Contraceptive Pills Versus Expectant Management for Retained Pregnancy Products
We speculate that the use of combined oral contraceptives may be a possible solution to promote the management of retained pregnancy products versus expectant management.
- Trial name
- NCT03230825
- Testing
- Oral contraceptive, Expectant management
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Second Trimester Abortion
TENS Unit To Decrease Pain After Laminaria Insertion
The purpose of the study is to learn more about the transcutaneous nerve stimulation (TENS) unit, an over-the-counter option for pain relief that is not a medication.
- Trial name
- NCT06529003
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS) unit
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Queen's Medical Center
Infertility, Recurrent Miscarriage
Effect of Influenza Vaccination on Donor Egg Recipient Outcomes
In this study the investigators propose a randomized controlled trial to evaluate the effect of influenza vaccination on clinical pregnancy rates among women undergoing in vitro fertilization as donor egg recipients.
- Trial name
- DE-FluVac (NCT02946177)
- Testing
- Influenza Vaccine, Sterile Saline
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Contraception, Abortion, Therapeutic
Nexplanon Application Post-Abortion (NAPA)
Women who receive Nexplanon immediately post abortion will be significantly more likely to be using the device 6 months after the procedure than those assigned to receive the device 2-4 weeks after the procedure.
- Trial name
- NAPA (NCT02037919)
- Testing
- Immediate Nexplanon Insertion, Post-op Nexplanon Insertion
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- Family Planning Associates Medical Group, LTD
Pregnancy, Infertility
Selenium Supplementation in Pregnancy
Serum levels of isolated anti-thyroperoxidase (TPOab) and anti-thyreoglobulin (Tgab) autoantibodies are strongly associated with an increased risk of miscarriage and premature deliveries in euthyroid pregnant women.
- Conditions
- Pregnancy, Infertility, Auto-immune Thyroiditis
- Trial name
- Serena (NCT01465867)
- Testing
- Selenium, Selenium + L-Thyroxine (LT4)
- Where
- 11 sites in Italy
- Volunteers
- 56 people
- Sponsor
- University of Roma La Sapienza
Complete Uterine Evacuation After Use of Study Drugs
Medical Abortion With Mifepristone + Misoprostol (13 - 22 Weeks)
A double-blind randomized controlled trial to compare a shorter interval between the administration of mifepristone and misoprostol (simultaneous administration compared to 24hours from administration of mifepristone to receipt…
- Trial name
- NCT01768299
- Testing
- Mifepristone, Misoprostol
- Where
- 3 sites in Vietnam
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Contraception
IUD Insertion Post First Trimester Abortion
The goal of this study is to provide better information about contraception to women having an abortion so that they are less likely to have another unintended unwanted pregnancy.
- Trial name
- NCT01174225
- Testing
- Flexi T 380(+) IUD, Nova T IUD
- Where
- Canada
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Early Pregnancy Loss, Abortion, Spontaneous
Surgical vs. Medical Abortion on Sexual Function After Early Pregnancy Loss
This study compares the medium-term effects of surgical and medical abortion on sexual function in women who have experienced early pregnancy loss (6-12 weeks gestation).
- Conditions
- Early Pregnancy Loss, Abortion, Spontaneous, Miscarriage, Pregnancy, Unwanted
- Trial name
- SF-EPL (NCT07646275)
- Testing
- mifepristone and misoprostol, Vacuum Aspiration
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Harran University
Lactation Suppressed
Cabergoline for Lactation Inhibition After Second-Trimester Abortion or Loss
This research study investigates the use of a drug, cabergoline, given immediately after second-trimester abortion or perinatal loss to decrease breast engorgement.
- Trial name
- LISTA (NCT04701333)
- Testing
- Cabergoline 1 MG
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Stanford University
Pregnancy Related, Pregnancy Loss
Massage as an Adjunct Approach to Care for Pregnant Women Who Have Experienced a Stillbirth
The goal of this mixed-methods single-arm study is to measure the feasibility of massage as an adjunct approach to care for pregnant women who have experienced a stillbirth.
- Trial name
- NCT05636553
- Testing
- Massage
- Where
- Australia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Fogarty Sarah
Retained Products of Conception, Hysteroscopy
Predictors of Successful Office Operative Hysteroscopy Using a Mini-Resectoscope
The goal of this observational study is to identify predictors of successful removal of benign intrauterine pathology using a mini-resectoscope during office operative hysteroscopy without anesthesia in adult women with suspected…
- Conditions
- Retained Products of Conception, Hysteroscopy, Endometrial Polyp Benign, Endometrial Polyp
- Trial name
- NCT07875985
- Testing
- Office Operative Hysteroscopy Using the Karl Storz Mini-Resectoscope Without Anesthesia
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Shaare Zedek Medical Center
Intra-uterine Residua
Non Surgical Management for Uterine Residua After Pregnancy Termination, Abortion or Delivery
The aim of the study is to find out whether conservative treatment - expectant management or medical therapy using misoprostol is beneficial in the case of uterine residua, and which treatment is better.
- Trial name
- NCT01134926
- Testing
- misoprostol
- Where
- Israel
- Volunteers
- 23 people
- Sponsor
- HaEmek Medical Center, Israel
Postoperative Pain
Flurbiprofen Axetil for Uterine Contraction Pain
Uterine contraction pain is a common problem after abortion. Optimal analgesic for such suffering is still needed to be guaranteed.
- Trial name
- FAUCOP (NCT00725218)
- Testing
- Saline, Flurbiprofen Axetil
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Nanjing Medical University
Robertsonian Translocation
Management of Robertsonian Translocation PGT-SR Attempts
to analyze if a probe strategy choice for PGT-SR studies of Robertsonian translocations (RT) influences the fate of embryos? Few studies discussed the importance of probe choices.
- Trial name
- NCT05109962
- Where
- France
- Volunteers
- 148 people
- Sponsor
- University Hospital, Montpellier