Clinical trials: Post-Acute COVID19 Syndrome
Long COVID Symptoms, Long COVI
Persistent COVID-19 Registry in Navarre.
The goal of this observational study is to deepen our understanding of long COVID by determining the prevalence of the main complications and medium- to long-term sequelae of COVID-19 in Navarre.
- Trial name
- PERSICOV-19 (NCT07417176)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacion Miguel Servet
Long COVID
A Multi-Center, Individually-Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Superiority Trial to Evaluate the Efficacy of the Combination of Maraviroc and Atorvastatin for the Treatment of Subjects With Long COVID
The IMPACT Long Covid Treatment clinical study (IMPACT-LC) is testing two repurposed and previously approved drugs, Maraviroc and Atorvastatin, for the treatment of non-hospitalized subjects with Long COVID.
- Trial name
- IMPACT-LC (NCT06974084)
- Testing
- Maraviroc (MVC), Atorvastatin, 10mg, 20mg, 40mg
- Where
- United States
- Volunteers
- 252 people
- Sponsor
- HealthBio, Inc.
Long COVID, Heart Rate Variability (HRV)
Effects os Physiotherapeutic Rehabilitation on Function Autonomic and Inflammatory in Patients With Long Covid
Introduction: Long COVID is characterized by persistent symptoms that persist for weeks or months after the acute phase of infection, with a significant impact on the cardiovascular and autonomic systems.
- Conditions
- Long COVID, Heart Rate Variability (HRV), Cardiac Biomarkers, Inflammatory Biomarkers
- Trial name
- LongCovidRehab (NCT07046208)
- Testing
- physiothreapy protocol
- Volunteers
- 58 people
- Sponsor
- Universidade do Estado do Pará
Post-COVID-19 Syndrome
EFFECT OF COGNITIVE BEHAVIORAL THERAPY ON DEPRESSION AND QUALITY OF LIFE IN PATIENTS WITH POST COVID-19
The goal of this clinical trial is to test the effect of Rehacom on depression and Quality of life in post covid -19 patients. The main question it aims to answer is: Is a cognitive rehabilitation therapy will improve depression…
- Trial name
- NCT05981872
- Testing
- rehacom
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Multiple Sclerosis, Long COVID
Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues
This study is for people who have multiple sclerosis, acute leukemia (in remission), or long-COVID and a Body Mass Index over 27 and may struggle with cognitive issues such as remembering information, concentrating, or making…
- Conditions
- Multiple Sclerosis, Long COVID, Long Covid19, Obese
- Trial name
- NCT06171152
- Testing
- Liraglutide Pen Injector [Saxenda], Medication Diary
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago
COVID-19, Long-COVID
Symptom-based Rehabilitation Compared to Usual Care in Post-COVID - a Randomized Controlled Trial
Inpatient, multimodal rehabilitation represents one of the most important interventions in the disease management of post/long COVID.
- Trial name
- RELOAD (NCT05172206)
- Testing
- symptom-focused rehabilitation, usual care
- Where
- 8 sites in Germany
- Volunteers
- 132 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Covid19
Efficacy of Adaptogens in Patients With Long COVID-19
The aim of this clinical trial of a fixed combination of standardized extracts from Rhodiola rosea roots, Schisandra chinensis berry and Eleutherococcus senticosus root (ADAPT-232) in COVID-19 patients is to demonstrate possible…
- Trial name
- NCT04795557
- Testing
- ADAPT-232 oral solution
- Where
- Georgia
- Volunteers
- 100 people
- Sponsor
- Swedish Herbal Institute AB
Post-COVID-19 Syndrome, COVID-19
Evaluation Of The Chronic Effects Of Covıd-19 Infection On The Respiratory System
The aim of this study is to evaluate whether there are chronic effects in the pulmonary system and systemic level in individuals in the post COVID19 period in order to elucidate the involvement of inflammation after recovery.
- Trial name
- NCT06439134
- Testing
- Pulmonary Ultrasound, Respiratory Function Test
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
SARS-CoV Infection
Chemoprevention Clinical Trial of COVID-19: Hydroxychloroquine Post Exposure Prophylaxis
Protocol summary Title A Prospective, randomized, adaptive phase II/III clinical trial, controlled, open-label, chemoprevention, 3-arms, parallel, multi-centred, to A Prospective, randomized, clinical trial, controlled…
- Trial name
- APCC-19 (NCT04597775)
- Testing
- hydroxychloroquine
- Volunteers
- 93 people
- Sponsor
- Regional Center for Disease Control and Prevention, Jordan
COVID Long-Haul
Long COVID-19 [11C]CPPC Study
The goal of this study is to evaluate the safety of using the [5-cyano-N-(4-(4-[11C]Methylpiperazin-1-yl)-2-(Piperidin-1-yl)Phenyl)Furan-2-carboxamide] ([11C]CPPC) radiotracer in positron emission tomography (PET) imaging of…
- Trial name
- NCT06223971
- Testing
- [11C]CPPC Injection
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
COVID-19, Post-Acute COVID-19
Genetic Risk Factors for Multi-system Inflammatory Syndrome in Children and Pediatric Post COVID Condition
We will perform Whole Exome Sequencing on DNA from saliva. We will include: Children with a history of MIS-C; children with post-COVID condition; and controls in order to identify rare, high impact genetic variants in…
- Conditions
- COVID-19, Post-Acute COVID-19, Post-Acute COVID19 Syndrome, Multi-System Inflammatory Syndrome in Children
- Trial name
- GRIP (NCT05722717)
- Testing
- Saliva collection at home
- Where
- Netherlands
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Human ARDS, Coronavirus Infection
Post-intensive Care Follow-up of Patients Hospitalized for an Acute Respiratory Distress Syndrome Caused by COVID-19
For the last years, studies have described the " Post-intensive care Syndrome " (PICS), which consists in alteration of quality of life, cognition, autonomy and psychological disorders within the months after intensive-care.
- Trial name
- RE-CoV-ERY (NCT04619368)
- Testing
- Follow up calls
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Toulouse
Postural Orthostatic Tachycardia Syndrome
Efficacy and Safety Study of Efgartigimod in Adults With Post-COVID-19 POTS
The study aims to investigate the safety, tolerability, efficacy, pharmacodynamics (PD), pharmacokinetics (PK), and immunogenicity of efgartigimod compared to placebo in participants with post-COVID-19 postural orthostatic…
- Trial name
- POTS (NCT05633407)
- Testing
- Efgartigimod
- Where
- 11 sites in United States
- Volunteers
- 53 people
- Sponsor
- argenx
Post COVID Condition
RECLAIM Adaptive Platform Trial for PCC Treatments
RECLAIM is a Phase III, multi-domain, randomized, controlled, adaptive platform trial, designed to evaluate efficacy and safety of repurposed medications in patients with post-COVID condition (PCC).
- Trial name
- RECLAIM (NCT07280572)
- Testing
- Metformin, colchicine
- Where
- Netherlands
- Volunteers
- 1,250 people
- Sponsor
- Janneke van de Wijgert
Long COVID, Long Covid19
RECOVER-VITAL: Platform Protocol to Measure the Effects of Antiviral Therapies on Long COVID Symptoms
This study is a platform protocol designed to be flexible so that it is suitable for a wide range of settings within health care systems and in community settings where it can be integrated into COVID-19 programs and subsequent…
- Trial name
- RECOVER-VITAL (NCT05595369)
- Testing
- Experimental: Paxlovid 25 day dosing, Experimental: Paxlovid 15 day dosing
- Where
- 69 sites in United States, Puerto Rico
- Volunteers
- 963 people
- Sponsor
- Kanecia Obie Zimmerman
Covid19, Viral Syndrome
Cardiopulmonary Rehabilitation in COVID-19 Longhaulers
This study will test the efficacy of treadmill exercise combined with supplemental oxygen during exercise and recovery for the treatment of persistent post-acute COVID-19 symptoms.
- Trial name
- NCT04898205
- Testing
- Treadmill Exercise, Concentrated Oxygen, Concentrated Air
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Noah Greenspan
COVID-19, Post-acute COVID-19 Syndrome
Hemostatic Profile of Post COVID-19/Long COVID-19 Patients
The present study aims at assessing long-term hemostatic profile of patients recovered from COVID-19 acute infection that remain asymptomatic (POST-COVID) versus patients with residual symptoms (LONG-COVID) through the employment…
- Trial name
- LCV (NCT05721066)
- Testing
- ClotPro assessment, Laboratory analysis, Interview
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- IRCCS Policlinico S. Donato
COVID-19, Long Haul
Digital Cognition Study During Long-COVID
The persistence of the COVID-19 disease symptoms, such as extreme fatigue, shortness of breath, cardiovascular complications, depression and anxiety, pain, brain fog, loss of taste/smell, headaches as well as loss of memory has…
- Trial name
- DIGICOG (NCT06391970)
- Testing
- Cognitive screening
- Where
- Luxembourg
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Post COVID-19 Syndrome
Randomized Double-Blind Phase 2 Study of Allogeneic HB-adMSCs for the Treatment of Chronic Post-COVID-19 Syndrome
This study will enroll up to 80 subjects with Chronic Post COVID-19 Syndrome. Subjects will receive four intravenous injections of either allogeneic HB-adMSC's or a placebo over 10 weeks with two follow-up visits and an end of…
- Trial name
- HBPCOVID02 (NCT05126563)
- Testing
- HB-adMSCs (allogeneic)
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Hope Biosciences Research Foundation
Long COVID, Long COVID Symptoms
A Pilot Randomized Controlled Trial of Homeopathic Treatment for Long COVID
A small-scale test of the intervention, trial design and methods to explore the cumulative effectiveness of two commonly used prescribing strategies for patients with long COVID: Treatment A - prescribing a specific homeopathic…
- Trial name
- long COVID POD (NCT07694232)
- Testing
- Treatment A: Treatment by a homeopath prescribing a specific homeopathic remedy for long COVID, a course of individually tailored treatment by a homeopath
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- St. Mary's University, Twickenham