Clinical trials: Post-Acute COVID19 Syndrome
Long-COVID, Long COVID-19
Pursuing Reduction in Fatigue After COVID-19 Via Exercise and Rehabilitation (PREFACER): A Randomized Feasibility Trial
Long COVID is a complex condition that affects approximately 1.4 million Canadians following SARS-CoV-2 infection. Fatigue is the most common symptom of Long COVID.
- Conditions
- Long-COVID, Long COVID-19, Post-COVID-19 Syndrome, Post-COVID Syndrome
- Trial name
- PREFACER (NCT06156176)
- Testing
- COVIDEx
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Lawson Research Institute of St. Joseph's
Respiratory Function Tests, Long COVID
Late Respiratory Consequences of SARS-CoV-2 Pneumonia
The goal of this observational study is to learn about the respiratory system in post-COVID syndrome. The main question aims to answer: how the post-COVID syndrome alters the lung function Participants will be asked to perform…
- Trial name
- NCT05812196
- Testing
- Lung function test, COVID infection
- Where
- Hungary
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Szeged University
Long COVID
Evaluation of the Effectiveness of Breathing Control Technique on Long COVID Symptoms at the Reunion University Hospital
Despite the controversy, on October 6, 2021, the World Health Organization (WHO) recognized Long Coronavirus disease (COVID) by officially defining it: " symptoms appeared 3 months after the onset of the primary infection by the…
- Trial name
- COCO-Long'Run (NCT05851859)
- Testing
- Cardiac coherence
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
COVID-19
Small Airway Disease And Bronchial Hyperreactivity In Patients With Post Acute Covid-19 Syndrome
The aim of this work is to estimate the frequency of small airway disease and/or the bronchial hyperreactivity in follow up of postacute covid survivors.
- Trial name
- NCT06374420
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
COVID-19, Cognitive Dysfunction
Long-Covid: Treatment of Cognitive Difficulties
The purpose of the study is to explore the potential effectiveness of two common low-dose interventions, one targeting cognitive difficulties and the other targeting affective difficulties on quality of life and cognition in…
- Trial name
- COV-COG (NCT05167266)
- Testing
- Psychoeducation
- Where
- 5 sites in Belgium
- Volunteers
- 130 people
- Sponsor
- University of Liege
Long COVID, Chronic Fatigue Syndrome
Vagus Nerve Stimulation as Treatment for Long Covid
Many patients do not recover following Covid infection. The resulting illness is called Long Covid. Because there is no agreed upon treatment for this ailment, the research team has decided to do an open label pilot study using…
- Trial name
- NCT05608629
- Testing
- Transcutaneous Non-Invasive Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Post COVID Condition
SuperCAP Program to Improve Cognition and Daily Functioning in Post-COVID-19 Condition
The goal of this study is to determine whether the SuperCAP intervention program is superior to control in reducing disability from baseline to the post-intervention assessment in people with Post-COVID-19 Condition.
- Trial name
- NCT07530757
- Testing
- SuperCAP intervention program, Psychoeducational intervention
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Post-acute Sequelae SARS-CoV-2 Infection (PASC)
TDCS-potentiated Generalization of Cognitive Training in the Rehabilitation of Long COVID Symptoms
The overarching goals of this study are to employ cognitive testing to understand how transcranial direct current stimulation (tDCS), when used concurrently with cognitive training tasks, can affect cognitive impairment symptoms…
- Trial name
- NCT05589272
- Testing
- Active tDCS
- Where
- United States
- Sponsor
- University of Minnesota
Post COVID Syndrome Long Covid, Post COVID Syndrome
Whole-Body Electrostimulation for Functional Recovery in Post-COVID Syndrome
Post-COVID syndrome is a condition that affects some people after recovering from the acute phase of COVID-19. Common symptoms include persistent fatigue, reduced physical capacity, and difficulties performing everyday…
- Conditions
- Post COVID Syndrome Long Covid, Post COVID Syndrome, Long COVID Fatigue, Long Covid
- Trial name
- WB-EMS PostCOV (NCT07312357)
- Testing
- Whole-Body Electromyostimulation Suit
- Volunteers
- 30 people
- Sponsor
- Universidad Rey Juan Carlos
Covid19, Post-acute Covid-19 Syndrome
Physical Training in Patients With POTS After Covid-19
Covid-19 has the potential to affect physical, cognitive and psychological functions in multiple ways. It has been clear that a significant proportion of patients with Covid-19 develop long-term symptoms.
- Conditions
- Covid19, Post-acute Covid-19 Syndrome, Postural Orthostatic Tachycardia Syndrome
- Trial name
- POTS-ReCOV (NCT05094622)
- Testing
- Physical exercise program
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Post COVID Condition, Chronic Pain
Effect of Non-Invasive Neuromodulation on Primary Chronic Pain, Including Post-COVID-19
The aim of this study is to analyse whether there is an advantage in adding low-intensity electrical stimulations to the vagus nerve with electrodes in the outer ear to control pain and fatigue in people with primary chronic…
- Conditions
- Post COVID Condition, Chronic Pain, Healthy
- Trial name
- NCT06689345
- Testing
- taVNS - transauricular vagal nerve stimulation, rPMS - repetitive peripheric magnetic stimulation, rTMS - repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Federal University of ABC
Covid19, Postviral Syndrome
ExoFlo™ Infusion for Post-Acute COVID-19 and Chronic Post-COVID-19 Syndrome
This is a Phase I/II trial to evaluate the safety and efficacy of intravenous (IV) administration of bone marrow mesenchymal stem cell derived extracellular vesicles (EV), ExoFlo, as treatment for Post-Acute COVID-19 and Chronic…
- Conditions
- Covid19, Postviral Syndrome, Dyspnea
- Trial name
- NCT05116761
- Testing
- Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles, Saline
- Sponsor
- Direct Biologics, LLC
SARS-CoV-2
Post-Marketing Safety Study of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA-1273 COVID-19 Vaccine in the United States
The goal of this study is to add to the ongoing active and passive safety signal detection through signal refinement and, if needed, evaluation of potential safety signals related to taking the SARS-CoV-2 mRNA-1273 vaccine.
- Trial name
- NCT04958954
- Where
- United States
- Volunteers
- 50,000,000 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
COVID-19, Post-COVID-19 Syndrome
Cohort Follow-up of Epidemic and Neuroimaging for Patients During the 1st Wave of the COVID-19 in China
Our main objective is to analyze the development of physical impact, mental health and blood profile over follow-up time during the 1st wave of the COVID-19.
- Conditions
- COVID-19, Post-COVID-19 Syndrome, Acute COVID-19, Post-Acute COVID-19
- Trial name
- NCT05745805
- Testing
- Simultaneous cortico-spinal magnetic resonance imaging, Serum
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Covid19
Enhancing COVID Rehabilitation With Technology
In March 2020, the World Health Organization (WHO) declared the novel coronavirus (COVID-19) a global pandemic. Ontario has confirmed more than 547,000 cases of COVID-19 since testing began.
- Trial name
- ECORT (NCT05019963)
- Testing
- NexJ Connected Wellness, Usual Care
- Where
- Canada
- Volunteers
- 106 people
- Sponsor
- University of Ottawa
Long COVID-19 Syndrome, COVID 19
Evaluating the Impact of a Functional and Cognitive Strategy in Patients With Long Covid-19
This study aims to evaluate the impact of a functional and cognitive rehabilitation strategy compared to evidence-based informational messages, on functional capacity, cognitive abilities, quality of life, and disease progression…
- Conditions
- Long COVID-19 Syndrome, COVID 19, Noncommunicable Disease, Hypertension
- Trial name
- NCT06871293
- Testing
- Functional and cognitive rehabilitation strategy, Evidence-Based Informational Support
- Where
- Colombia
- Volunteers
- 374 people
- Sponsor
- Fundación Cardioinfantil Instituto de Cardiología
Chronic Fatigue Syndrome, Long COVID
Endothelial Dysfunction in Post-infection Fatigue Syndromes
Post-infection chronic fatigue syndromes, such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-COVID-19 condition (Long Covid), are conditions primarily characterized by debilitating fatigue.
- Trial name
- NCT06463106
- Where
- Austria
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- FH Joanneum Gesellschaft mbH
Long COVID, POTS - Postural Orthostatic Tachycardia Syndrome
Long COVID Immune Profiling
Parasympathetic nervous system (PNS) is part of the body's autonomic nervous system(PNS) protects body against inflammation. Study shows that reduced PNS function activity is associated with persistent inflammation.
- Conditions
- Long COVID, POTS - Postural Orthostatic Tachycardia Syndrome, Autonomic Dysfunction
- Trial name
- NCT06027255
- Testing
- IL-6, cytokines (IL-17, and IFN-ɣ), Compass 31
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Chronic Cough, Long COVID
Etiology Analysis of Chronic Cough After COVID-19 Infection and Research on the Efficacy of ICS or ICS/LABA
In this real-world study, we retrospectively classified the causes of chronic cough in patients, analyzed the prevalence of cough-variant asthma, and prospectively evaluated and compared the improvement of cough symptoms and…
- Trial name
- NCT06503939
- Where
- China
- Volunteers
- 750 people
- Sponsor
- Xiangya Hospital of Central South University
COVID-19
Nutrition and LOComotoric Rehabilitation in Long COVID-19
Long COVID is a new phenomenon, in which individuals who experienced a SARS-CoV-2 infection still experience one or more symptoms, such as exercise intolerance, fatigue and/or muscle pains in addition to other COVID-related…
- Trial name
- UNLOCK (NCT05254301)
- Testing
- Intervention group
- Where
- Belgium
- Volunteers
- 65 people
- Sponsor
- Universitair Ziekenhuis Brussel