Clinical trials: Post-Acute Sequelae of COVID-19
Post-COVID-19 Syndrome
Balneotherapy for Patients With Post-acute Coronavirus Disease (COVID) Syndrome
The goal of this randomized controlled study is to evaluate the effects of balneotherapy (BT) and aquatic exercises in patients with post-acute COVID syndrome (PACS).
- Trial name
- NCT05765591
- Testing
- Balneotherapy and aquatic exercises
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Parc de Salut Mar
Post-COVID-19 Syndrome, Lung Fibrosis
Anti-Inflammatory and Anti-Fibrotic Drugs in Post COVID-19 Pulmonary Fibrosis
In this study we aim to evaluate the radiological and functional changes in post-acute covid-19 pulmonary fibrosis patients in relation to anti-inflammatory and/or antifibrotic drugs prescribed during and after covid-19 pneumonia.
- Trial name
- NCT05648734
- Testing
- Corticosteroids alone, Corticosteroids + Colchicine, Corticosteroids + Pirfenidone
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mansoura University
Long COVID
Lithium Long COVID Dose-finding Study
This open-label study will assess if lithium dosages of 30-45mg/day are associated with greater symptomatic benefit than dosages of 10-15mg/day previously assessed among 50 patients with long COVID.
- Trial name
- NCT06108297
- Testing
- Lithium
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- State University of New York at Buffalo
Post Covid-19 Condition
Functional Ability, Symptoms and Quality of Life in Patients With Post Covid-19 Condition
Up to 20% of patients with Covid-19 develop symptoms that last more than 3 months, which is known as long Covid or Post-Covid-19 condition.
- Trial name
- LC-cohort (NCT05699512)
- Testing
- Multiprofessional, tailored rehabilitation
- Where
- Finland
- Volunteers
- 400 people
- Sponsor
- Helsinki University Central Hospital
Long Covid19
Effectiveness of Testofen Compared to Placebo on Long COVID Symptoms
This is a double blind, randomised, placebo-controlled trial to evaluate orally-dosed Testofen (a specialised extract of Trigonella foenum-graecum (Fenugreek) seed) compared to placebo on post COVID-19 symptoms in otherwise…
- Trial name
- NCT05795816
- Testing
- Testofen, Microcrystalline cellulose
- Where
- Australia
- Volunteers
- 150 people
- Sponsor
- RDC Clinical Pty Ltd
Post Acute COVID 19 Syndrome, Memory Impairment
HOBSCOTCH for People With Post Acute COVID-19 Syndrome (PACS)
The goal of this pilot study is to assess the feasibility of adapting and delivering the existing home-based epilepsy self-management intervention, HOBSCOTCH, for people with Post Acute Covid Syndrome (PACS).
- Conditions
- Post Acute COVID 19 Syndrome, Memory Impairment, Memory Dysfunction, Cognitive Dysfunction
- Trial name
- NCT06391489
- Testing
- HOBSCOTCH-PACS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Long COVID
Tele-exercise Training Program for Long COVID
Patients with long coronavirus disease (COVID-19) experience multisystem symptoms and reduced quality of life (QOL). Proactive interventions are needed to enhance health outcomes.To investigate the effects of a 12-week…
- Trial name
- NCT07553897
- Testing
- Telehealth exercise training program, Education and self-exercise
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Long COVID, Sars-CoV-2 Infection
Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID
The overarching goal of this study is to determine if baricitinib, as compared to placebo, will improve neurocognitive function, along with measures of physical function, quality of life, post-exertional malaise, effect of…
- Conditions
- Long COVID, Sars-CoV-2 Infection, Coronavirus Infections, COVID-19
- Trial name
- REVERSE-LC (NCT06631287)
- Testing
- Baricitinib
- Where
- 17 sites in United States
- Volunteers
- 550 people
- Sponsor
- Wes Ely
Post-Concussion Syndrome, COVID Long-Haul
Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)
The purpose of this study is to test the effect of Auricular Percutaneous Electrical Nerve Field Stimulation (a Neurostim device) on children with pain and Post Concussion symptoms.
- Conditions
- Post-Concussion Syndrome, COVID Long-Haul, COVID-19
- Trial name
- NCT04978571
- Testing
- percutaneous electrical nerve-field stimulation, PENFS, percutaneous electrical nerve-field stimulation, PENFS (COVID active device)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Children's Hospital of Orange County
Asthma, COPD
MUlti-nuclear MR Imaging Investigation of Respiratory Disease-associated CHanges in Lung Physiology
Lung magnetic resonance imaging (MRI) with proton and inhaled inert gases has demonstrated a clinical ability to provide valuable structural and functional information in lung disease.
- Conditions
- Asthma, COPD, Covid19, Long COVID
- Trial name
- MURDOCH (NCT04872309)
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Coronavirus Disease, COVID-19
The Effect of Smart Sensor Combined With APP for Individualized Precise Exercise Training in Long Covid-19
The coronavirus (COVID -19) has rapidly turned into a global pandemic. For patients diagnosed with COVID-19, it caused severe damage in the upper respiratory system and systemic complications, including the cardiovascular…
- Conditions
- Coronavirus Disease, COVID-19, Long Covid-19, Telerehabilitation
- Trial name
- NCT05922865
- Testing
- KNEESUP smart knee assistive device + KNEESUP care APP, Healthy consulation
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shang-Lin Chiang
Long COVID, Myocardial Injury
The Efficacy of Aerobic Exercise in the Rehabilitation of Patients With COVID-19-Related Myocardial Injury
A study of the efficacy of aerobic exercise based on cardiopulmonary exercise test in the rehabilitation of patients with COVID-19-related myocardial injury
- Trial name
- NCT06404411
- Testing
- Assigned interventions, conventional rehabilitation
- Volunteers
- 40 people
- Sponsor
- Chengdu Sport University
Long COVID Fatigue
A Trial of Shengmai Liquid for Long COVID Fatigue.
The goal of this clinical trial is to learn if Shengmai liquid works to treat Long Covid fatigue. It will also learn about the safety of Shengmai liquid.
- Trial name
- Shengmai LOFT (NCT06980636)
- Testing
- Shengmai Liquid
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing University of Chinese Medicine
SARS-CoV-2 Infection, COVID-19
An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID.
Following an infection with Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV2), one in ten people will experience persisting symptoms, or develop symptoms which can last for months and even years.
- Trial name
- ERASE-LC (NCT05911906)
- Testing
- Remdesivir
- Where
- 4 sites in United Kingdom
- Volunteers
- 73 people
- Sponsor
- University of Derby
Post-COVID-19 Syndrome, Fatigue Post Viral
Yoga Versus Health Education for the Treatment of Persistent Fatigue in Patients With Post COVID-19 Syndrome
Evaluation of the short- and medium-term effect of a yoga intervention in addition to routine care compared to health education in addition to routine care on fatigue in patients with post covid syndrome.
- Trial name
- YoFaPoCo (NCT05890599)
- Testing
- Yoga Therapy, Health Education
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Tuebingen
COVID-19, Long COVID-19
Effects of Physiotherapy Via Telerehabilitation in Patients With COVID-19
This study aims to evaluate the effects of Physiotherapy Via Video Calls on Cardiopulmonary Functions, Physical Function, Cognitive Function, Activity Daily Livings, and Quality of Life in Patients With COVID-19.
- Conditions
- COVID-19, Long COVID-19, Cardiopulmonary Function, Physical Function
- Trial name
- NCT06251011
- Testing
- Exercise training
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Chulabhorn Hospital
Post COVID-19 Condition
Prospective Multidisciplinary Post-COVID-19 Registry Tyrol
Longitudinal, prospective observational cohort study enrolling patients with persisting symptoms (> 12 weeks) after COVID-19 in a multidisciplinary care model.
- Trial name
- PRECISE (NCT05545332)
- Where
- Austria
- Volunteers
- 600 people
- Sponsor
- Medical University Innsbruck
COVID-19, COVID Long
Burden of Care of Long COVID Patients After Hospital Discharge
Since March 2020, 3.5 million people have been infected with SARS-COV2 in France, and about 250 000 patients have been hospitalized and successfully discharged.
- Trial name
- BLOC (NCT05073328)
- Testing
- COVID-19 required hospitalisation
- Where
- France
- Volunteers
- 68,822 people
- Sponsor
- Mikhail Dziadzko, MD, PhD
Post-COVID-19 Syndrome, Long COVID
ImPROving Quality of LIFe in the Long COVID Patient
The purpose of this study is to investigate the efficacy of orally administered nirmatrelvir/ritonavir compared with placebo/ritonavir to improve quality of life in non-hospitalized adult participants suffering from post-acute…
- Conditions
- Post-COVID-19 Syndrome, Long COVID, Long Covid19, COVID-19
- Trial name
- PROLIFIC (NCT05823896)
- Testing
- Nirmatrelvir/ritonavir
- Where
- Sweden
- Volunteers
- 219 people
- Sponsor
- Karolinska Institutet
Post-Acute COVID-19 Syndrome
Care for Veterans Post-COVID-19
The evidence-based Concordant Care approach involves engaging in processes that: 1) validate the patient's experience, 2) develop a shared understanding of the condition, and 3) create a patient-centered, whole health-oriented…
- Trial name
- NCT05787379
- Testing
- Concordant Care Training, Education Packet Training
- Where
- United States
- Volunteers
- 348 people
- Sponsor
- VA Office of Research and Development