Clinical trials: Post-Acute Sequelae of COVID-19
Conscripts, Military Induction Board
Prevalence of ENT Diseseas
The aim of the present study will be to evaluate in conscripts at the military induction board the prevalence of rhinosinusitis, the prevalence of HPV vaccinations, the prevalence of hearing impairments and the prevalence of…
- Conditions
- Conscripts, Military Induction Board, ENT Disease, Rhinosinusitis Chronic
- Trial name
- PrENT (NCT06105346)
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Post COVID-19 Condition (PCC)
Pilot Randomized Study of RD-X19 Tx Device in Subjects With PCC (Long Covid) in the Outpatient Setting
Duration of Treatment: 7 days, 2 times per day. Following Randomization on Week 1 Day 1, Subjects will continue to have televisits and rate symptoms and upright activity weekly during a 5 week follow up.
- Trial name
- EB-PCC-01 (NCT06113679)
- Testing
- RDX-19
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- EmitBio Inc.
COVID - 19
Effect of Pulmonary Rehabilitation and Physical Activity on COVID-19 Long-Term Symptoms (PuReCOVID)
This single-center, observational, longitudinal, retrospective and prospective study investigates the impact of Active Cycle of Breathing Technique (ACBT) and moderate daily physical activity on symptoms associated with long…
- Trial name
- PuReCOVID (NCT07046442)
- Testing
- Pulmonary Rehabilitation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Parma
Long COVID
Clinical and Biological Characterization of Post COVID-19 Syndrome
The goal of this observational study is to describe the symptoms that persist for more than 12 weeks after the acute episode in participants who had COVID-19, and compare the functional, socioeconomic and occupational effects…
- Trial name
- NCT05735782
- Testing
- Clinical, mental health and psychosocial profile of Post-COVID-19 syndrome, Diagnostic performance of echocardiographic and biological markers in Post-COVID-19 syndrome
- Where
- Argentina
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Arturo Jauretche National University
COVID-19, Post-COVID-19 Syndrome
Retinal Neurovascular Coupling in Patients Previously Infected With COVID-19
The Study objective is to measure retinal neurovascular coupling and blood flow parameters in patients previously infected with COVID-19, long COVID-19 and healthy age- and sex- matched control subjects
- Trial name
- NCT05650905
- Testing
- Dynamic Vessel Analyzer (DVA), Fourier domain optical coherence tomography (FDOCT), Optical coherence tomography (OCT)
- Where
- Austria
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Long COVID-19 Syndrome, Long COVID Symptoms
Epigenetic Changes in Long COVID Patients
The goal of this observational study is to improve the understanding of the biological mechanisms underlying long COVID and to identify molecular biomarkers that may support its diagnosis, prognosis, and future precision medicine…
- Trial name
- ECLIPSE (NCT07757620)
- Where
- 3 sites in Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Long COVID Symptoms
Vagal Approaches on Long COVID-19
The purpose of this study is to explore whether two general wellness products, alone or combined, can support individuals experiencing Long COVID symptoms.
- Trial name
- NCT07190105
- Testing
- Sonocea Sonic Augmentation Technology (SAT), Truvaga Electrical Vagus Nerve Stimulator
- Where
- United States
- Volunteers
- 546 people
- Sponsor
- Leidos Life Sciences
Long COVID, Vagus Nerve Stimulations
Vagus Nerve Stimulation for Post-COVID Syndrome
The aim of this study is to increase parasympathetic activity and decrease the severity of symptoms by providing vagal stimulation with the t-VNS method in order to suppress the increased sympathetic activity in patients with…
- Conditions
- Long COVID, Vagus Nerve Stimulations, Heart Rates, Autonomic Nervous System Disorders
- Trial name
- NCT05679505
- Testing
- Auricular transcutaneous vagus nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Neurocognitive Disorders, Cognitive Dysfunction
A Pilot Randomized Controlled Trial: CoINTEGRATE
The purpose of this study is to examine the feasibility of comprehensive multimodal individually tailored Cognitive Behavioral Therapy (CBT), Cognitive Rehabilitation Therapy (CRT), and modifiable lifestyle sessions.
- Conditions
- Neurocognitive Disorders, Cognitive Dysfunction, Traumatic Brain Injury, Multiple Sclerosis
- Trial name
- CoINTEGRATE (NCT05732285)
- Testing
- CRT, CBT, Modifiable lifestyle factors
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Long COVID, Post COVID-19 Condition
Effect of Hi-OxSR for the Treatment of Post COVID Condition
The RECLAIM study platform will be used to explore whether the use of the Hi-OxSR device improves the symptoms of post covid cognitive dysfunction.
- Conditions
- Long COVID, Post COVID-19 Condition, Post Acute Sequelae of COVID-19
- Trial name
- RECLAIM-HiOxSR (NCT06928506)
- Testing
- Hi-OxSR device, Hi-Ox device
- Where
- 3 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Long COVID
Optimising General Practice Long COVID Care - an Educational Intervention.
This trial will evaluate the feasibility of a pilot educational intervention for GPs that aims to enhance care and care outcomes among patients with long COVID at six general practices in the Ireland East region.
- Trial name
- GP-COV-ED (NCT06765421)
- Testing
- Intervention Group
- Volunteers
- 72 people
- Sponsor
- University College Dublin
Post-acute Covid-19 Syndrome
Homeopathic Treatment of Post-acute COVID-19 Syndrome
To determine whether an individually prescribed homeopathic medicine has an effect greater than a placebo and is a viable treatment option to improve fatigue and quality of life for patients suffering from the symptoms of…
- Trial name
- NCT05104749
- Testing
- Homeopathic Medication
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Southwest College of Naturopathic Medicine
COVID-19, Long-COVID
Symptom-based Rehabilitation Compared to Usual Care in Post-COVID - a Randomized Controlled Trial
Inpatient, multimodal rehabilitation represents one of the most important interventions in the disease management of post/long COVID.
- Trial name
- RELOAD (NCT05172206)
- Testing
- symptom-focused rehabilitation, usual care
- Where
- 8 sites in Germany
- Volunteers
- 132 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Long COVID
Effects of Sodium Pyruvate Nasal Spray in COVID-19 Long Haulers.
There are approximately 12 million Americans with COVID-19 Long Hauler Symptoms, including athletes. The symptoms include hypoxemia (low SaO2), fatigue, coughing/sneezing, dyspnea, trouble breathing, body aches, headaches.
- Trial name
- NCT04871815
- Testing
- sodium pyruvate nasal spray
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Cellular Sciences, inc.
Adjustment Reaction With Physical Symptoms
Use of Homeopathy in Patients Suffering From Long COVID-19
In some patients, coronavirus (COVID-19) can cause symptoms that last weeks or even months after the infection has gone. The aim of this study was to describe the effect of adjunctive individualized homeopathic treatment…
- Trial name
- LONGCOVIHOM (NCT06002230)
- Testing
- Homeopathic medicines
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- Michael Frass
Long COVID
Health-related Quality of Life and Long COVID
Background: Long COVID is estimated to affect 1.7 million people in the UK. One way of assessing the impact of long COVID is to measure quality-of-life through a standard questionnaire, which can then be used to understand the…
- Trial name
- OpenPROMPT (NCT05552612)
- Where
- United Kingdom
- Volunteers
- 7,574 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Post-COVID-19 Syndrome, Long COVID
Magnesium and Vitamin D Combination for Post-COVID Syndrome
The goal of this double-blind randomized controlled clinical trial is to determine the efficacy of the administration of magnesium chloride + vitamin D as an adjuvant in the treatment of post-Coronavirus Disease (COVID) syndrome.
- Conditions
- Post-COVID-19 Syndrome, Long COVID, Vitamin D Deficiency, Magnesium Deficiency
- Trial name
- NCT05630339
- Testing
- Magnesium chloride, Vitamin D
- Where
- Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Asthma, COPD
MUlti-nuclear MR Imaging Investigation of Respiratory Disease-associated CHanges in Lung Physiology
Lung magnetic resonance imaging (MRI) with proton and inhaled inert gases has demonstrated a clinical ability to provide valuable structural and functional information in lung disease.
- Conditions
- Asthma, COPD, Covid19, Long COVID
- Trial name
- MURDOCH (NCT04872309)
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
COVID-19, Post-COVID-19 Syndrome
Covid-19, Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) and Influenza Treatment System With Machine Learning
This is an open-tabled, one-arm observatory trial to assess the effectiveness and safety of the Autonomous Treatment System Based on Machine Learning in patients with Covid-19, Post-Acute Sequelae of SARS-CoV-2 infection and…
- Conditions
- COVID-19, Post-COVID-19 Syndrome, Influenza
- Trial name
- NCT06052527
- Testing
- Autonomous Treatment System for Covid-19, Post-Acute Sequelae of SARS-CoV-2 Infection and Influenza Based on Machine Learning
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Lizora LLC
Long COVID
Development of Voice Biomarkers of Frequent COVID-19 and Long Covid-related Symptoms Based on Data From Users of the Long COVID Companion App
The LIH DDP research team focuses its research topics on vocal biomarkers and Long COVID, among others. Voice is indeed a promising tool to monitor health, as it contains many information on our health and is easy to collect.
- Trial name
- EVO-LC (NCT07156994)
- Testing
- No Intervention: Observational Cohort
- Where
- Luxembourg
- Volunteers
- 300 people
- Sponsor
- Luxembourg Institute of Health