Clinical trials: Post-COVID-19
Long COVID
Utilizing Novel Blood RNA Biomarkers as a Diagnostic Tool in the Identification of Long COVID-19
The Primary objective of this study is to determine, using unblinded samples, if it is possible to develop an algorithm for the classification of specific blood RNA from patients with long COVID together and separately from the…
- Trial name
- NCT06311435
- Testing
- RNA Biomarker Blood Test
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- MaxWell Clinic, PLC
Covid19, Critical Illness
REmotely Monitored, Mobile Health-Supported High Intensity Interval Training After COVID-19 Critical Illness (REMM-HIIT-COVID-19)
REmotely Monitored, Mobile Health-Supported High Intensity Interval Training after COVID-19 critical illness (REMM-HIIT-COVID-19)
- Conditions
- Covid19, Critical Illness, High Intensity Interval Training, ICU
- Trial name
- REMMHIIT-COVID (NCT04664101)
- Testing
- REmotely Monitored, Mhealth (REMM) supported High Intensity Interval Training (HIIT), Comparator
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Duke University
Post COVID-19 Anosmia (Loss of Smell)
Investigating the Potential Role of Aerosolized Retinoic Acid, a Potent Vitamin A Metabolite for Treating COVID-19 Anosmia and Retinoic Acid Insufficiency .A Novel Approach for Regaining Sense of Smell.
Investigating the potential role of Aerosolized retinoic acid, a potent Vitamin A metabolite for treating COVID-19 Anosmia and retinoic acid insufficiency .A novel approach for regaining Sense of Smell.
- Trial name
- NCT05002530
- Testing
- Aerosolized 13 cis retinoic acid plus Vitamin D, Aerosolized All trans retinoic acid plus Vitamin D, Standard therapy
- Where
- 3 sites in China, Egypt and 1 more
- Volunteers
- 10,000 people
- Sponsor
- Kafrelsheikh University
Post COVID-19 Condition
Pilot Open Label Use of the Hi-OXSR for the Treatment of Post COVID-19 Cognitive Dysfunction
During the worldwide COVID-19 pandemic a large number patients reported different functional complaints one month or later after recovery from the acute infection.
- Trial name
- Hi-OXSR (NCT06379620)
- Testing
- Hi-OxSR Sequential Rebreathing mask (oxygen concentrator)
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- University Health Network, Toronto
Post-Acute COVID-19 Syndrome, Post-Acute COVID-19
Safety and Efficacy of Anakinra Treatment for Patients With Post Acute Covid Syndrome
The PRECISION is a proof-of-concept, phase II randomized clinical trial aiming to evaluate the efficacy and safety of anakinra in patients with Post-Acute COVID Syndrome (PACS) of the pro-inflammatory respiratory phenotype.
- Conditions
- Post-Acute COVID-19 Syndrome, Post-Acute COVID-19, Long COVID
- Trial name
- PRECISION (NCT05926505)
- Testing
- Anakinra 149 MG/ML Prefilled Syringe [Kineret]
- Where
- 24 sites in Germany, Greece and 2 more
- Volunteers
- 182 people
- Sponsor
- Hellenic Institute for the Study of Sepsis
COVID-19
Respiratory Function 3 Months After Hospital Discharge in Critically Ill COVID-19 Patients
The objective of this single-center retrospective observational study is to describe spirometric abnormalities and their impact on 6-minute walk test (6MWT) and the physical component summary (PCS) of the SF-36 quality of life…
- Trial name
- NCT05249842
- Testing
- Spirometric evaluation, Physical component summary, 6MWT
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital Sao Domingos
Close Contact Transmission
Exploratory Study of Aerosol Inhalation of FB2001 for Post-exposure Prophylaxis of COVID-19 Close Contacts
This is a single-arm, open-label, dose ramp-up exploratory clinical trial to evaluate the efficacy, safety and tolerance of aerosol inhalation of FB2001 as post-exposure prophylaxis among close contacts of COVID-19 patients.
- Trial name
- NCT05415241
- Testing
- FB2001
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
SARS-CoV2 Infection, Hip Fractures
Hip Fracture and COVID-19
Hip fracture in the elderly is a worldwide public health issue and a medical challenge for early postoperative rehabilitation. More than 2 million people are treated annually with an annual incidence between 100 and 300/100,000…
- Conditions
- SARS-CoV2 Infection, Hip Fractures, Surgery
- Trial name
- COLCOVID (NCT04944329)
- Testing
- Hip fracture surgery
- Where
- France
- Volunteers
- 73,661 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
COVID-19, Cancer
SARS-CoV-2 Specific Immune Response After COVID-19 Vaccination in Cancer Patients
Our study highlights a low degree of neutralization-afforded protection mounted by CoronaVac in cancer patients when compared with healthy volunteers, especially patients who received chemotherapy.
- Trial name
- NCT05313074
- Testing
- CoronaVac vaccine
- Where
- Thailand
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Thailand
Parosmia
Stellate Ganglion Block With Lidocaine for the Treatment of COVID-19-Induced Parosmia
Chronic olfactory dysfunction, both hyposmia and parosmia, from the COVID-19 pandemic is a growing public health crisis, affecting up to 1.2 million people in the United States.
- Trial name
- Stella (NCT06055270)
- Testing
- Stellate Ganglion Block
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Long COVID Syndrome
Effectiveness of a Personalized In-home Telerehabilitation Program on Self-Care in Patients With Long COVID
The goal of this clinical trial is to evaluate whether a 12-week tele-rehabilitation programme roduces medium-term improvements in self-management, fatigue and quality of life in patients affected by persistent COVID.
- Trial name
- RESPICARE (NCT06822179)
- Testing
- Education for self-management, Personalised exercise program, Usual Care
- Where
- Spain
- Volunteers
- 57 people
- Sponsor
- CEU San Pablo University
Long Covid19
Chronic-disease Self-management Program in Patients Living With Long-COVID in Puerto Rico
This is a pilot non-randomized-controlled trial to evaluate the impact of "Tomando control de su salud", an evidenced-based intervention for chronic disease self-management in the quality of life of patients living with…
- Trial name
- NCT06208696
- Testing
- "Tomando control de su salud" (Spanish Chronic Disease Self-Management)
- Where
- Puerto Rico
- Volunteers
- 47 people
- Sponsor
- University of Puerto Rico
Post ICU Syndrome, Chronic Pain
Early Care Program for the Management of Post-ICU Syndrome and Chronic Pain After COVID-19 Infection.
COVID-19 (coronavirus 2019) disease has led to a large number of hospital admissions, many of which require admission to intensive care (ICU).
- Conditions
- Post ICU Syndrome, Chronic Pain, Covid-19
- Trial name
- PAIN-COVID (NCT04394169)
- Testing
- Intervention program
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Hospital Clinic of Barcelona
Covid19
The Effect of Virtual Reality Exercises on Patients With Post-COVID-19 Condition
This study aims to investigate (I) the effectiveness of motion-controlled video game-based VR exercises on pain, fatigue, functional capacity, mood, and quality of life in patients with PCC, and (II) to determine whether they are…
- Trial name
- NCT04983394
- Testing
- Virtual Realty Exercises, conventional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people
- Sponsor
- Cumhuriyet University
Post-Acute COVID-19 Syndrome
Stem Cell Study for Long COVID-19 Neurological Symptoms
The purpose of this research study is to test the safety and benefit of a human cord blood derived stem cell infusion as a treatment for individuals with post COVID-19 neurological problems.
- Trial name
- COVID-19 (NCT06156241)
- Testing
- Stem Cell
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Charles Cox
COVID-19
ECMO Braile Biomédica® in COVID-19 Patients
Retrospective data collection to evaluate the gas transfer capacity of the Braile Biomédica® OxyPrime® ECMO BRCoating® Membrane Oxygenator in COVID-19 patients during the pandemic.
- Trial name
- ECMO_COVID (NCT06086405)
- Testing
- Patients underwent cardiorespiratory support
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Braile Biomedica Ind. Com. e Repr. Ltda.
Nurse, Student
Psychological Impact of the Covid-19 Pandemic on Student Nurses
The World Health Organization (WHO) declared in early 2020 the emergence of a new highly contagious SARS-CoV-2 coronavirus responsible for a global public health emergency.
- Conditions
- Nurse, Student, Post Traumatic Stress Disorder, COVID-19
- Trial name
- StudentCov (NCT04402229)
- Where
- 2 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Versailles Hospital
Opioid Use Disorder
Remote Methadone Ingestion Surveillance Trial (RMIST)
The Remote Methadone Ingestion Surveillance Trial (RMIST) will explore a potential method of methadone ingestion surveillance that may mitigate patient safety risks of take-home methadone treatment regimens while minimizing the…
- Trial name
- NCT05259501
- Testing
- RMIST
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Texas Southwestern Medical Center
COVID-19
Symptoms ,Signs and Complications That Appear After Infection With Covid 19 Virus
1. Raise awareness for persistent post-COVID syndrome (PPCS). 2. Rising tide of physical and psychological disabilities that have been described in post-COVID patients.
- Trial name
- NCT05185700
- Testing
- post covid 19 symtoms
- Volunteers
- 180 people
- Sponsor
- Assiut University
Long COVID, Post COVID-19 Condition
Taurine Supplementation in Adolescents With Post-COVID Condition
The COVID-19 pandemic has swept across the globe, affecting millions of individuals with varying degrees of severity. While many individuals recover from the acute phase of the infection, a significant proportion continue to…
- Conditions
- Long COVID, Post COVID-19 Condition, PASC Post Acute Sequelae of COVID 19
- Trial name
- TaurineLCPeds (NCT07682402)
- Testing
- Taurine
- Volunteers
- 30 people
- Sponsor
- University of Alberta
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