Clinical trials: Post-COVID-19
Covid19
EVALUATING THE EFFICIENCY OF BREATHING EXERCISES PERFORMED BY POST-COVID TELEMEDICINE: Randomized Controlled Study
As an important non-drug intervention in the treatment of respiratory tract diseases, respiratory rehabilitation training is increasingly accepted in clinical practice.
- Trial name
- NCT04771598
- Testing
- Breathing exercise with the phone application, Breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Tokat Gaziosmanpasa University
COVID-19, Sleep Apnea
CPAP Efficacy in Post-COVID-19 Patients With Sleep Apnea
This is a prospective, observational study evaluating the relationship between severity of sleep apnea with severity of cognitive fog and if treatment of sleep apnea with CPAP improves cognitive fog in a cohort of post COVID…
- Trial name
- BreathePA (NCT06052514)
- Testing
- Continuous positive airway pressure
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Venkatesh Krishnamurthy
Covid19
Prevention and Treatment of Patient Before, During, and After Covid-19 Infection
AntiCov-220 prevents and treats before, during, and after infection with SARS-CoV-2. The composition is fractionally extracted from herbs (Ascorbic Acid, L-Arginine hydrochloride, Adenosma glutinosum extract, Eclipta prostrata…
- Trial name
- AntiCov-220 (NCT05043324)
- Testing
- AntiCov-220
- Where
- 2 sites in United States, Vietnam
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Nguyen Thi Trieu, MD
SARS-CoV-2 Infection, COVID-19
An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID.
Following an infection with Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV2), one in ten people will experience persisting symptoms, or develop symptoms which can last for months and even years.
- Trial name
- ERASE-LC (NCT05911906)
- Testing
- Remdesivir
- Where
- 4 sites in United Kingdom
- Volunteers
- 73 people
- Sponsor
- University of Derby
Long COVID
Utilizing Novel Blood RNA Biomarkers as a Diagnostic Tool in the Identification of Long COVID-19
The Primary objective of this study is to determine, using unblinded samples, if it is possible to develop an algorithm for the classification of specific blood RNA from patients with long COVID together and separately from the…
- Trial name
- NCT06311435
- Testing
- RNA Biomarker Blood Test
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- MaxWell Clinic, PLC
COVID-19
Effects of Aerobic Exercise in Patients With Post COVID-19
Many structures and organs are adversely affected after COVID-19. The most obvious and common problem is lung involvement. In the pathology report of the patients, it has been shown that there are changes such as diffuse alveolar…
- Trial name
- NCT05231408
- Testing
- High-intensity interval aerobic exercise training, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gazi University
PostCovid
Interprofessional Rehabilitation for Patients With Post-COVID Condition
Since 2020, millions of individuals have been infected with SARS-CoV-2 virus and a substantial proportion continue to experience persistent symptoms that impair functional capacity, limit daily activities, and negatively affect…
- Trial name
- Post-COVID (NCT07821385)
- Testing
- Interprofessional cognitive group rehabilitation
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Danderyd Hospital
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Multisystem Inflammatory Syndrome in Children (MIS-C)
COVID-19: Pediatric Research Immune Network on SARS-CoV-2 and MIS-C
The primary objectives of this study are: To determine the proportion of children with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) related death, rehospitalization or major complications after infection with…
- Conditions
- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Multisystem Inflammatory Syndrome in Children (MIS-C), Coronavirus Disease 2019 (COVID-19)
- Trial name
- PRISM (NCT04588363)
- Testing
- SARS-CoV-2 and/or MIS-C Exposure
- Where
- 20 sites in United States
- Volunteers
- 244 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid19, Corona Virus Infection
Clinical, Functional, Immunological and Genetic Factors on the Severity of the Course of Coronavirus Infection
The purpose of the program. To determine the clinical, functional, immunological, and genetic factors affecting the severity of the course of acute coronavirus infection COVID-19 and PostCovid syndrome, in order to develop…
- Trial name
- NCT04987853
- Testing
- Clinical and functional analysis, Neurological analysis, Immunological analysis:
- Where
- Kazakhstan
- Volunteers
- 300 people
- Sponsor
- National Research Center for Cardiac Surgery, Kazakhstan
COVID-19
Phase 3 Study of Novavax Vaccine(s) as Booster Dose After mRNA Vaccines
This is an open-label Phase 3 study evaluating the immunogenicity and safety of Novavax vaccine(s) with Matrix-M™ adjuvant (ancestral strain NVX-CoV2373 and an alternative strain and/or multivalent Novavax vaccine) as booster…
- Trial name
- NCT05875701
- Testing
- NVX-CoV2373, SARS-CoV-2 rS antigen/Matrix-M Adjuvant
- Where
- 5 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Novavax
Covid19
Physical Activity Post COVID-19
THis study aims to examine PA trajectory, and potential behaviour-change factors least 12 months after COVID-19, across different levels of acute disease severity, and specifically in people with and without Long COVID.
- Trial name
- PA-COVID19 (NCT04768257)
- Testing
- Physical activity
- Where
- Spain
- Volunteers
- 148 people
- Sponsor
- University of Alcala
Post COVID-19 Condition (PCC)
Basel Long COVID-19 Cohort Study and Digital Long COVID Substudy
The Basel Long COVID Cohort Study (BALCoS) is a registry-based cohort study that focuses on the patients' present health status, symptoms, the course of these symptoms, and potential mechanisms involved.
- Trial name
- BALCoS/DiLCoS (NCT05781893)
- Testing
- Digital intervention (DiLCoS), Data collection
- Where
- Switzerland
- Volunteers
- 196 people
- Sponsor
- University Hospital, Basel, Switzerland
Aspergillosis
Immune Regulation in Chronic Aspergillus Infection After COVID-19 Infection
This study aims to collect clinical cases and follow-up data from patients with chronic pulmonary aspergillosis, post-COVID-19 aspergillosis, and post-COVID-19 patients without aspergillosis.
- Trial name
- NCT06135597
- Testing
- This is a blood test without regarding to intervention nor diagnostic tests
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Post-Acute COVID-19 Syndrome, Long COVID-19
Synbiotic Therapy for NP-PASC
Gut microbiome dysbiosis has been noted in patients with Post-acute sequelae (PASC) of Severe Acute Respiratory Syndrome-CoronaVirus -2 (SARS-CoV-2).
- Trial name
- NCT06620406
- Testing
- Synbiotic IVS-1, Maltodextrin
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Columbia University
COVID-19, Post COVID-19
Virtual Physical Rehabilitation for Patients Living with Long COVID
The purpose of this study is to investigate whether a timely, virtual home-based physical rehabilitation program for patients living with long COVID can improve functional mobility compared to usual care.
- Conditions
- COVID-19, Post COVID-19, Long COVID
- Trial name
- NCT05298878
- Testing
- Intervention Group: Virtual home-based rehabilitation plus usual outpatient care
- Where
- 2 sites in Canada
- Volunteers
- 132 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Anosmia, Covid19
Olfactory Disfunction and Co-ultraPEALut
Olfactory dysfunction is common among patients with Corona-Virus-Infection-Disease (COVID)-19, and up to 30% of patients may report persistent disorders of smell or taste as a long-term sequelae.
- Conditions
- Anosmia, Covid19, Hyposmia, Parosmia
- Trial name
- NCT04853836
- Testing
- co-ultraPEALut, Olfactory Rehab, PEA-LUT 1 sachet
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Of Perugia
Long COVID-19 Syndrome, Chronic Fatigue Syndrome
A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial
IRB approval date 14-APR-2024 and public at https://plataformabrasil.saude.gov.br/login.jsf since IURB approval Long COVID is a multi-systemic condition comprising often severe and persistent symptoms (longer than 12 weeks) that…
- Trial name
- REVIVE (NCT06128967)
- Testing
- Fluvoxamine Maleate 100 MG, Metformin Extended Release Oral Tablet
- Where
- 6 sites in Brazil
- Volunteers
- 399 people
- Sponsor
- Cardresearch
Coping Behavior, Mental Health Issue
The Changes of Coping With Stressful Events Among Adolescents Under the COVID-19 Pandemic.
This study aims to describe the changes in coping strategies used by adolescents for stressful life events under the background of epidemic normalization; and explore the causes of coping strategy changes of stressful life events…
- Trial name
- NCT05435469
- Testing
- Questionnaires
- Where
- China
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
COVID-19
Low-intensity Aerobic Training Associated With Global Muscle Strengthening in Post-COVID-19
The study called "Effect of low-intensity aerobic training associated with global muscle strengthening in post-COVID-19 individuals" wants to check if doing easy workouts and strengthening muscles can make breathing problems…
- Trial name
- NCT06161740
- Testing
- muscle strengthening
- Where
- Brazil
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Centro Universitário Augusto Motta
Long COVID
Tele-exercise Training Program for Long COVID
Patients with long coronavirus disease (COVID-19) experience multisystem symptoms and reduced quality of life (QOL). Proactive interventions are needed to enhance health outcomes.To investigate the effects of a 12-week…
- Trial name
- NCT07553897
- Testing
- Telehealth exercise training program, Education and self-exercise
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Tri-Service General Hospital (TSGH)
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