Clinical trials: Post-Dural Puncture Headache
Postdural Puncture Headache, Sphenopalatine Ganglion Block
The Effect of Ganglion Sphenopalatine Block (GSP-block) Versus Placebo on Postdural Puncture Headache
The purpose of this study is to evaluate the effect of the ganglion sphenopalatine block (GSP block) on postdural puncture headache.
- Trial name
- NCT03652714
- Testing
- Ganglion sphenopalatine block with local anesthetic
- Where
- 5 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Postdural Puncture Headache
Effect of Coffee on Postdural Puncture Headache After Cesarean Section
The purpose of this study is to investigate the effects of postoperative coffee consumption on postdural puncture headache (PDPH) and analgesic use in women undergoing cesarean section with spinal anesthesia.
- Trial name
- NCT07410741
- Testing
- Coffee Consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Pain Score (VAS)
Nebulized Dexmedetomidine or Lidocaine for Treatment of Post Dural Puncture Headache in Parturients Undergoing Elective Cesarean Section Under Spinal Anesthesia
Post-dural puncture headache (PDPH) is a well-recognized and potentially serious complication of subarachnoid block. While advancements in spinal needle design have reduced its incidence in recent years, PDPH still affects a…
- Trial name
- NCT06607861
- Testing
- saline group, dexmedetomidine group, lidocaine group
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Minia University
Postdural Puncture Headache
Role of Prophylaxis by Oral Fluid Supplementation in Prevention of Postdural Puncture Headache
Postdural puncture headache (PDPH) is defined, according to the International Headache Society, as any headache develops within 5 days after a lumbar puncture.
- Trial name
- PROPHYDRA (NCT02859233)
- Testing
- Lack of hyperhydration
- Where
- 4 sites in France
- Volunteers
- 554 people
- Sponsor
- Nantes University Hospital
Post-Dural Puncture Headache
Comparison of Nebulized Neostigmine/Atropine Versus Lignocaine in Treating Acute Post-dural Puncture Headache Following Subarachnoid Block in Parturient Undergoing Elective Cesarean Section. A Randomized, Clinical Trial.
Post-dural puncture headache (PDPH) is a common and debilitating complication of spinal anesthesia in pregnant patients undergoing cesarean sections, with an incidence ranging from 0.5% to 2% (1).
- Trial name
- NCT06824025
- Testing
- lidocaine group ( nebulized lidocaine + saline) total volume 4 ml
- Where
- Egypt
- Volunteers
- 111 people
- Sponsor
- Minia University
Hypotension in Pregnant Women, Headache in Pregnant Women
Prediction of Hypotension and Postdural Puncture Headache by Carotid Artery Corrected Flow Time
Anesthesia for cesarean delivery can be provided through general or neuraxial anesthesia (spinal or epidural). Hypotension is a common complication of both methods.
- Trial name
- NCT07372313
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University
Post-Dural Puncture Headache
Is Theophylline More Effective Than Sumatriptan in the Treatment of Post-dural Puncture Headache
Objectives: To compare the safety and efficacy of oral theophylline versus oral sumatriptan in the treatment of post-dural puncture headache (PDPH).
- Trial name
- NCT04257851
- Testing
- Theophylline Anhydrous Oral Tablet, Sumatriptan Succinate Oral Tablet
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
PDPH, Post Dural Puncture Headache
Efficacy of Sphenopalatine Block Compared to Blood Patch in the Management of Post-dural Puncture Headaches
Post-dural puncture headache (PDPH) is an iatrogenic complication following a dural puncture, which may occur after lumbar puncture, spinal or epidural anesthesia.
- Trial name
- BRECHE (NCT07354464)
- Testing
- Sphenopalatine Ganglion Block, Blood patch
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hypotension After Neuraxial Anesthesia, Cesarean Section
Comparing Spinal, Epidural, and Dural Puncture Epidural Anesthesia for Cesarean Delivery: Hemodynamics and Block Quality
The goal of this clinical trial is to compare three regional anesthesia techniques (spinal, epidural, and dural puncture epidural anesthesia) in healthy pregnant women undergoing planned (elective) cesarean delivery.
- Conditions
- Hypotension After Neuraxial Anesthesia, Cesarean Section, Anesthesia, Obstetrical, Post-Dural Puncture Headache
- Trial name
- NCT07883733
- Testing
- Spinal Anesthesia, Epidural Anesthesia, Dural Puncture Epidural Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Post-Dural Puncture Headache
Nebulized Dexmedetomidine Versus Oral Sumatriptan in Treatment of Post Dural Puncture Headache in Cesarean Section
comparison between oral sumatriptan and Nebulized Dexmedetomidine in Post Dural Puncture Headache in Cesarean Section
- Trial name
- NCT06514040
- Testing
- Precedex, Sumatriptan 25 mg
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Cesarean Section, Postoperative Nausea and Vomiting (PONV)
Restrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section
Spinal anesthesia for elective cesarean section is frequently associated with hemodynamic instability and postoperative complications such as postoperative nausea and vomiting (PONV) and delayed gastrointestinal recovery.
- Conditions
- Cesarean Section, Postoperative Nausea and Vomiting (PONV), Postdural Puncture Headache (PDPH), Postoperative Ileus
- Trial name
- NCT07440667
- Testing
- Restrictive intraoperative crystalloid fluid strategy (≤3 mL/kg/h), Liberal intraoperative crystalloid fluid strategy (>3 mL/kg/h)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Nigde Omer Halisdemir University
Central Nervous System Infections, Pseudotumor Cerebri
A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control
This study will compare the VerTouch device to the conventional palpation technique for performing diagnostic and therapeutic neuraxial procedures.
- Conditions
- Central Nervous System Infections, Pseudotumor Cerebri, Neurological Disorder, Cancer
- Trial name
- NCT04796935
- Testing
- Tactile Imaging (VerTouch), Control (palpation)
- Where
- 3 sites in United States
- Volunteers
- 95 people
- Sponsor
- IntuiTap Medical, Inc
Theophylline, Sumatriptan
Theophylline, Versus Sumatriptan and Gabapentin in The Treatment of Post-Dural Puncture Headache
The aim of this study is to compare the safety and efficacy of theophylline, sumatriptan, and gabapentin in the treatment of post-dural puncture headache.
- Conditions
- Theophylline, Sumatriptan, Gabapentin, Post-Dural Puncture Headache
- Trial name
- NCT07515456
- Testing
- Theophylline, Sumatriptan, Gabapentin
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University
Post-Dural Puncture Headache
Contribution of Ondansetron to Preventing Post-Dural Puncture Headaches Following Spinal Anesthesia
A prospective, bicentric, randomized, double-blind controlled study including parturients scheduled for elective caesarean delivery under spinal anaesthesia and randomized and assigned to one of the two groups: Group O…
- Trial name
- OPDPH (NCT06444737)
- Testing
- Intravenous ondansetron, Intravenous normal saline
- Where
- Tunisia
- Volunteers
- 300 people
- Sponsor
- Mongi Slim Hospital
Headache
Comparison Of Different Doses Of Intrathecal Neostigmine In Prevention Of Post-Dural Puncture Headache
We hypothesized that; intrathecal administration of neostgmine in spinal anesthesia may have a beneficial role in reduction of the incidence or severity of PDPH.
- Trial name
- NCT04905953
- Testing
- Neostigmine
- Where
- Egypt
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Cairo University
Leukemia, Lymphoma
A Randomized Study Evaluating the Incidence of Post Lumbar Puncture Headache With Atraumatic Needles in Hematology
Lumbar punctures are implemented for the diagnosis of patients with hematologic symptoms as well as for the intrathecal chemotherapy injections.
- Trial name
- SPPLAASH (NCT03126045)
- Testing
- Standard needle, Atraumatic needle
- Where
- 2 sites in France
- Volunteers
- 68 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Post-Dural Puncture Headache, Sphenopalatine Ganglion Block
Effectiveness of Sphenopalatine Ganglion Block for Post-Dural Puncture Headache
The objective of the study is to determine the effectiveness of Spheno-Palatine (SP) ganglion block to alleviate the pain of post-dural puncture headache (PDPH).
- Trial name
- NCT03430531
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Milton S. Hershey Medical Center
Post-Dural Puncture Headache
Sphenopalatine Block Versus Greater Occipital Nerve Block in PDPH
Management of postdural puncture headache (PDPH) has always been challenging for anesthesiologists. PDPH not only increases the misery of the patient, but the length of stay and overall cost of treatment in the hospital also…
- Trial name
- NCT05235256
- Testing
- bilateral sphenopalatine ganglion block, bilateral greater occipital nerve block, lidocaine plus dexamethasone
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Post-Lumbar Puncture Headache
A Prospective Study of a Modified Lumbar Puncture (LP) Procedure That Reduces Post-Lumbar Puncture Headaches (PLPH) in Patients
The purpose of this study is to o determine whether the modified LP procedure reduces the incidence of PLPH to 5% or lower, to determine whether the modified LP procedure reduces the frequency of epidural blood patch (EBP) usage…
- Trial name
- NCT06062446
- Testing
- Modified Lumbar Puncture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston