Clinical trials: Post-ERCP Acute Pancreatitis.
Abdominal Pain, Post-ERCP Acute Pancreatitis
A Trial of 0.025 Wire Guided Cannulation Versus Current Practice 0.035 Wire Guided Cannulation
The aim of this study is to determine whether using a smaller wire results in a higher success rate at endoscopic retrograde cholangiopancreatography (ERCP), and lower incidence of adverse events
- Trial name
- NCT01408264
- Testing
- Conventional 0.035 guidewire, Olympus Visiglide 0.025 guidewire
- Where
- China
- Volunteers
- 184 people
- Sponsor
- Chinese University of Hong Kong
Post-ERCP Pancreatitis, Pancreatitis, Acute Necrotizing
The Efficacy of Pancreatic Duct Stenting With Rectal Indomethacin in Preventing Post-ERCP Pancreatitis
With the development of endoscopic technology, ERCP has been widely used in the diagnosis and treatment of pancreatobiliary diseases, and has become the first treatment for most of the biliary and pancreatic diseases.
- Trial name
- NCT03643900
- Testing
- pancreatic duct stenting, rectal indomethacin
- Where
- China
- Volunteers
- 618 people
- Sponsor
- First People's Hospital of Hangzhou
Pancreatitis Biliary, Pancreatitis Acute Biliary
Indomethacin for Biliary ERCP Patients
This study is a randomized clinical trial evaluating the efficacy of rectal indomethacin in preventing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis in patients undergoing biliary ERCP who have a history…
- Conditions
- Pancreatitis Biliary, Pancreatitis Acute Biliary, Pancreatitis, Post-ERCP Pancreatitis
- Trial name
- NCT07661498
- Testing
- indomethacin
- Where
- United States
- Volunteers
- 860 people
- Sponsor
- University of California, San Francisco
Post ERCP Pancreatitis, Acute Pancreatitis (AP)
Cold Water Papillary Irrigation Plus Rectal NSAIDs vs Rectal NSAIDs Alone for Post-ERCP Pancreatitis (COLD)
Post-ERCP pancreatitis is the most frequent complication of endoscopic retrograde cholangiopancreatography (ERCP). Rectal non-steroidal anti-inflammatory drugs (NSAIDs) are the current standard prophylaxis.
- Trial name
- COLDHUVN (NCT07885852)
- Testing
- Cold water irrigation of the papilla, Rectal NSAID (diclofenac 100 mg)
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- University Hospital Virgen de las Nieves
Post-ERCP Acute Pancreatitis
Trial of Aggressive Hydration Versus Rectal Indomethacin for Prevention of Post-ERCP Pancreatitis
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a commonly performed endoscopic procedure used to treat pancreato-biliary pathology.
- Trial name
- AHRI-PEP (NCT03629600)
- Testing
- Lactated Ringer, Rectal Form Indometacin
- Where
- India
- Volunteers
- 352 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Post-ERCP Acute Pancreatitis
Study of Effectiveness of Thoracic Epidural Analgesia for the Prevention of Acute Pancreatitis After ERCP Procedures
For 40 years, the post-ERCP (endoscopic retrograde cholangiopancreatography) pancreatitis has been the most frequent adverse effect of endoscopic transpapillary interventions.
- Trial name
- NCT01964066
- Testing
- ERCP, Thoracic epidural analgesia, Premedication
- Where
- Russia
- Volunteers
- 491 people
- Sponsor
- Volgograd State Medical University
Pancreatitis, Acute, ERCP
Post-ERCP Pancreatitis - Prophylactic Measures Implementation Study (PEP-PROMIS)
This is a prospective, observational (non-interventional), multicenter study that will look at how often inflammation of the pancreas (called post-ERCP pancreatitis, or PEP) occurs after an endoscopic procedure known as ERCP.
- Conditions
- Pancreatitis, Acute, ERCP, Prophylaxis
- Trial name
- PEP-PROMIS (NCT07244432)
- Where
- 13 sites in Czechia, Slovakia
- Volunteers
- 1,135 people
- Sponsor
- Branislav Kuncak
Post-ERCP Acute Pancreatitis
Oral Losartan in Prevention of Post-ERCP Paancreatitis
Oral losartan given in the dose of 50 mg one hour before ERCP was studied in the prevention of post ERCP pancreatitis in 50 patients indicated for ERCP in comparison with another 50 patients underwent ERCP without receiving oral…
- Trial name
- NCT04049734
- Testing
- oral losatan
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Cholangitis, Post-ERCP Acute Pancreatitis
Optimal Placement Duration of Pancreatic Duct Stent
A randomized controlled trial to determine the optimal placement duration of pancreatic duct stents (PDS) inserted during ERCP: 2 vs 4 weeks
- Conditions
- Cholangitis, Post-ERCP Acute Pancreatitis, Stent Dislodgement
- Trial name
- NCT04691674
- Testing
- Endoscopy
- Where
- South Korea
- Volunteers
- 122 people
- Sponsor
- DongGuk University
Post-ERCP Acute Pancreatitis
An European Multi-centre Cohort Study for Unravelling Pharmacokinetic and Genetic Factors Underlying Post-ERCP Pancreatitis
Endoscopic retrograde cholangiopancreatography (ERCP) comes with a risk for post-ERCP pancreatitis (PEP), which accounts for considerable morbidity, high healthcare expenditure, and death.
- Trial name
- G-PEP (NCT05267379)
- Testing
- Take blood samples
- Where
- Netherlands
- Volunteers
- 700 people
- Sponsor
- Radboud University Medical Center
Pancreatitis, Acute
Epinephrine Sprayed on the Papilla Versus Sterile Water Sprayed on the Papilla for Preventing Pancreatitis After Endoscopic Retrograde Cholangiopancreatography
This multicentre randomised controlled trial included patients aged >18 years with an indication for ERCP and naive major papilla.
- Trial name
- NCT02959112
- Testing
- Epinephrine, Sterile water, Indomethacin Rectal Suppository
- Where
- Mexico
- Volunteers
- 548 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Post-ERCP Acute Pancreatitis
Papillary Epinephrine Injection vs Rectal Indomethacin
Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is the most common and one of the most undesirable major adverse events after endoscopic retrograde cholangiopancreatography (ERCP), causing significant…
- Trial name
- PEIR-PEP (NCT07173179)
- Testing
- Epinephrine injection, Indomethacin
- Where
- Turkey (Türkiye)
- Volunteers
- 504 people
- Sponsor
- Duzce University
Post-ERCP Acute Pancreatitis
Epinephrine Sprayed on the Papilla for the Prevention of Post-ERCP Pancreatitis
Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) has been a well-recognized complication with significant morbidity and even mortality.
- Trial name
- NCT02839356
- Testing
- epinephrine, normal saline
- Where
- China
- Volunteers
- 670 people
- Sponsor
- Anhui Provincial Hospital
Endoscopic Retrograde Cholangiopancreatography (ERCP), Choledocholithiasis
Role of Prophylactic Aggressive Hydration to Prevent Post-ERCP Pancreatitis
Endoscopic Retrograde Cholangiopancreatography, also called ERCP, is a procedure used to diagnose and treat disorders of the bile ducts and pancreas.
- Conditions
- Endoscopic Retrograde Cholangiopancreatography (ERCP), Choledocholithiasis, Bile Duct Disorder, Biliary Obstruction
- Trial name
- NCT07417020
- Testing
- Aggressive intravenous hydration with lactated Ringer's solution, Standard intravenous hydration with lactated Ringer's solution
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Lahore General Hospital
Post-ERCP Acute Pancreatitis
Rectal Indomethacin vs Intravenous Ketorolac
Endoscopic retrograde cholangiopancreatography (ERCP) is an essential procedure that can be complicated by post-ERCP pancreatitis (PEP). Indomethacin and ketorolac are two medications used to prevent PEP.
- Trial name
- NCT05664074
- Testing
- Rectal indomethacin, IV ketorolac
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- David Vitale MD
Post-ERCP Acute Pancreatitis
Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
Acute pancreatitis is the most common and feared complication of ERCP, occurring after 1% to 30% of procedures. Since 2012, a multicenter RCT was published in NEJM, indomethacin use in high risk patients was considered a…
- Trial name
- Indomethacin (NCT02002650)
- Testing
- Pre-ERCP rectal Indomethacin, Post-operational Rectal Indomethacin
- Where
- 6 sites in China
- Volunteers
- 2,600 people
- Sponsor
- Air Force Military Medical University, China
Post-ERCP Acute Pancreatitis
7 cm vs. 5 cm Pancreatic Stents for the Prevention of Post-ERCP Pancreatitis in High-risk Patients
Acute pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). The incidence of post-ERCP pancreatitis (PEP) is estimated to be 10% to 15% in high-risk patients.
- Trial name
- NCT04145336
- Testing
- 5cm 5-Fr PDS, 7cm 5-Fr PDS, Indomethacin
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Air Force Military Medical University, China
Post-ERCP Acute Pancreatitis
Randomized Trial of Rectal Indomethacin and Papillary Spray of Epinephrine Versus Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
This research is being done to see if using a combination of rectal indomethacin and epinephrine spray during endoscopy, can prevent pancreatitis that may occur after ERCP (a type of gastrointestinal endoscopy).
- Trial name
- INDIEH (NCT02116309)
- Testing
- Rectal Indomethacin, Epinephrine
- Where
- 4 sites in United States, India
- Volunteers
- 948 people
- Sponsor
- Johns Hopkins University
Post-ERCP Acute Pancreatitis
The Prophylactic Effect of Stilamin on Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis
Pancreatitis are one of the most common complications of post-ERCP (Endoscopic Retrograde Cholangiopancreatography), the incidence rate is 5\&-10%, how to prevent PEP and hyperamylasemia is an important issue, somatostatin is…
- Trial name
- NCT01431781
- Testing
- Stilamin+common daily treatment, Common daily practice
- Where
- 15 sites in China
- Volunteers
- 908 people
- Sponsor
- Changhai Hospital
Post-ERCP Acute Pancreatitis
ENBD After Endoscopic Sphincterotomy Plus Large-balloon Dilation for Preventing PEP
Endoscopic retrograde cholangiopancreatography (ERCP) has become one of the most important techniques in the treatment of bile duct stones.
- Trial name
- NCT02830984
- Testing
- EST+LBD+ENBD, EST+LBD
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Anhui Provincial Hospital