Clinical trials: Post-Extraction Sockets
Alveolar Socket Preservation
Clinical, Histological and Micro-computed Tomographic Evaluation of Neoformed Tissue in Post-extraction Sockets Covered With Platelet-rich Fibrin (PRF) Membrane: a Randomized Controlled Trial
The platelet-rich fibrin (PRF), belongs to a new generation of plasma concentrate with biomechanical processing simplified and without the need for handling blood biochemistry.
- Trial name
- NCT02300246
- Testing
- Platelet-Rich Fibrin
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Marcos de Oliveira Barceleiro
Loss of Teeth Due to Extraction, Alveolar Bone Loss
Relate Tooth Alveolar Extraction Socket Anatomy to Alveolar Remodeling Rate
In patients that are going to be subjected to a tooth extraction in the anterior maxillary (from canine to canine) does the position of the intact alveolar socket related to maxillary basal bone interferes with the rate of…
- Conditions
- Loss of Teeth Due to Extraction, Alveolar Bone Loss, Bone Resorption
- Trial name
- NCT01963884
- Testing
- Tooth Extraction, Cone-Beam technology evaluation, Measure Alveolar Socket Remodeling
- Where
- Portugal
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Pain, Postoperative, Post Operative Swelling
Effect Of Autologous Platelet Rich Fibrin On Post-Operative Complications And Healing Following The Extraction
As post-operative pain, infection inflammation and infections are the main complications after the surgical extraction of the lower third molar the aim of this study is to compare the healing effects of PRF administered…
- Conditions
- Pain, Postoperative, Post Operative Swelling, Trismus, Soft Tissue Healing
- Trial name
- PRF (NCT06609967)
- Testing
- application of PRF, application of conventional surgicel
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Alveolar Osteitis
Efficacy of 0.2 % Digluconate Chlorhexidine Mouthwash for Preventing Alveolar Osteitis After Third Molar Extraction
The purpose of this study is to demonstrate the efficacy of 0.2 % digluconate chlorhexidine mouthwash in the prevention of alveolar osteitis following third molar extraction and to evaluate the safety and local tolerability.
- Trial name
- NCT02382809
- Testing
- DC071
- Where
- 18 sites in Estonia, France and 2 more
- Volunteers
- 414 people
- Sponsor
- Pierre Fabre Medicament
Tooth Extraction, Atrophy of Edentulous Alveolar Ridge
Ridge Preservation With New Class of Osteoplastic Materials
Return to normal life and shortening rehabilitation period of patients after surgical removal of teeth is important and urgent social problem.
- Trial name
- RP (NCT02155764)
- Testing
- Octacalcium phosphate, Bio-Oss, Tricalcium phosphate
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Osteogenesis Imperfecta, Total Absence of Permanent Teeth
Site Preservation After Tooth Extraction
This study is mainly targeted affected teeth which could not be retained, and patients are willing to undergo implant repair at the later stage.
- Conditions
- Osteogenesis Imperfecta, Total Absence of Permanent Teeth, Tooth Socket
- Trial name
- NCT05258019
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Surgery, Oral
Guided Bone Regeneration Using Polydioxanone (PDO) Membrane in Sockets After Tooth Extraction
The goal of this clinical trial is to compare the maintenance of socket volume in the groups treated by a resorbable regenerative membrane (Plenum® Guide) covered or not with mucous tissue, with control without treatment.
- Trial name
- NCT06015906
- Testing
- Plenum® Guide, Plenum® Oss, Tooth extraction
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- M3 Health
Alveolar Osteitis
Assessment of Ozone Therapy for Management of Post-Extraction Localized Alveolar Osteitis
This clinical study investigates the effectiveness of ozone therapy in comparison to conventional treatment for alveolar osteitis (AO), a common painful complication following tooth extraction.
- Trial name
- NCT07106333
- Testing
- Topical Ozone Therapy, Irrigation with saline
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Alveolar Ridge Resorption After Extraction
Alveolar Ridge Changes Post Tooth Extraction With Socket Shield Without Immediate Implant Placement"
This study aimed to evaluate the dimensional changes in the alveolar ridge after tooth extraction using the socket shield technique without immediate implant placement.
- Trial name
- CBCT (NCT06658860)
- Testing
- Modified Socket Shield Technique, Conventional Tooth Extraction
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Soaad Tolba Mohammed Tolba Badawi
Xenograft Model
Effect of Xenogeneic Collagen Matrix on the Peri-implant Tissues of Immediate Implants.
The present clinical trial will try to demonstrate the efficacy of stable xenogeneic collagen matrix in maintaining the vestibular coronal soft tissue volume and the stabilization of mid-buccal margin position in immediate…
- Trial name
- NCT04980313
- Testing
- Xenogenic collagen matrix, Autogenous connective tissue graft
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Loss of Teeth Due to Extraction, Alveolar Bone Loss
Regeneration of Alveolar Sockets With rhBMP-2-loaded Bovine Bone Mineral
Aim of the present investigation will be to evaluate the efficacy and safety of a granulate of rhBMP-2- loaded bovine bone mineral (rhBMP-2-BBM) as alveolar bone regeneration procedure following tooth extraction.
- Conditions
- Loss of Teeth Due to Extraction, Alveolar Bone Loss, Edentulous Alveolar Ridge
- Trial name
- PROTEOGRAFT (NCT05717478)
- Testing
- rhBMP-2-BBM, Bio-Oss+Bio-Gide
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Unrestorable Dentition, Post-Extraction Sockets
An Assessment of Bone Augmentation in Post-Extraction Sockets
When a tooth is extracted the ridge of bone that held the tooth in place begins to heal and over time new bone grows to fill the empty space left by the missing tooth.
- Trial name
- FMD-007 (NCT00641316)
- Testing
- AtraumaticTeeth Extraction, Atraumatic Teeth Extraction/Grafted Extraction Sockets
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Post-extraction Bone Regeneration
Socket Preservation With Er:YAG and Nd:YAG Lasers
Alveolar bone regeneration after laser-assisted extraction will be compared with bone regeneration after standard extraction procedure.
- Trial name
- NCT04232202
- Testing
- Er:YAG and Nd:YAG lasers, Standard extraction
- Where
- Slovenia
- Volunteers
- 29 people
- Sponsor
- Krizaj d.o.o.
Decayed Teeth
Effect of Bone Marrow Mononuclear Cell Layer Seeded on Platelet-rich Fibrin on an Alveolar Socket After Extraction
Bone marrow aspiration from maxillary tuberosity will be centrifuged to separate the bone marrow mononuclear cell layer using the density gradient separation method, then it will be seeded in a platelet-rich fibrin membrane and…
- Trial name
- NCT05465421
- Testing
- bone marrow aspiration from maxillary tuberosity and BMMNCs separation to be seeded on PRF and used for socket preservation
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Socket Preservation, Alveolar Ridge Deficiency, Alveolar Ridge Preservation
Comparison of The Post-Extraction Dimensional Alterations Following Ridge Preservation Using Autogenous Partially and Completely Demineralized Dentin Grafts Versus Autogenous Whole-tooth Graft
For alveolar ridge preservation after extraction of a non-restorable maxillary non-molar tooth, will the use of Autogenous partially or completely demineralized dentin grafts result in similar ridge dimensions compared to…
- Trial name
- NCT05766137
- Testing
- Alveolar ridge preservation
- Volunteers
- 45 people
- Sponsor
- Cairo University
Tooth Loss
Bone Remodeling After Immediate Implant Placement With and Without Bone Grafting
This study compares two ways of placing a dental implant on the day of tooth extraction. One method will place a additional bone graft (derived from bovine bone) and the other group will not have the graft placed.
- Trial name
- NCT02174198
- Testing
- BioOss Collagen at the time of implant placement
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Columbia University
Tooth Loss / Rehabilitation, Tooth Extraction
Ovate Pontic Versus Essix Provisional After Tooth Extraction and Alveolar Ridge Preservation (Pontic-Essix)
This randomized controlled trial compares two provisional socket-sealing concepts following single non-molar tooth extraction and alveolar ridge preservation: a fixed, tooth-supported, 3D-printed ovate pontic provisional…
- Conditions
- Tooth Loss / Rehabilitation, Tooth Extraction, Alveolar Bone Loss, Alveolar Ridge Augmentation
- Trial name
- Pontic-Essix (NCT07748871)
- Testing
- Bio-Oss Collagen, Mucograft Seal, Fixed 3D-printed ovate pontic provisional restoration
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Bern
Tooth Extraction, Tooth Extraction Site Healing
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
The goal of this randomized clinical trial is to assess whether β-TCP (Beta-Tricalcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction.
- Conditions
- Tooth Extraction, Tooth Extraction Site Healing, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- BTCPARPBV (NCT07638319)
- Testing
- Neocement Inject P® (Beta-Tricalcium Phosphate)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Alveolar Bone Preservation, Bone Graft
Clinical Study of Injectable Ceramics Bone Graft Substitute Containing rhBMP-2
This is a prospective, outcomes assessor-blinded, randomized study to evaluate the efficacy and safety of "Inject BMP(Injectable Ceramics Bone Graft Substitute Containing rhBMP-2)" for socket preservation after extraction of a…
- Trial name
- rhBMP-2 (NCT02714829)
- Testing
- Inject BMP, ExcelOS-inject
- Volunteers
- 88 people
- Sponsor
- BioAlpha Inc.
Socket Preservation
Post Extraction Alterations Following Ridge Preservation In The Esthetic Zone Using Partially Demineralized Autogenous Dentine Graft Versus Xenograft
the aim of this study is to establish if there are clinical, radio-graphical and histomorphometrical differences between using Partially Demineralized Dentin graft versus Xenograft in the esthetic zone.
- Trial name
- NCT06552793
- Testing
- autogenous partially demineralized dentin graft, Xenograft
- Where
- Egypt
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cairo University