Clinical trials: Post-Extraction Sockets
Socket Preservation
Bone Material's Histomorphometric Analysis In Socket Preservation
This is a prospective, multicentre, parallel-group, randomized controlled, single blinded (participant) trial aims to compare the investigational medical device with standard of care in dental treatment addressing the…
- Trial name
- BM-HIS-SP (NCT06740110)
- Testing
- Tooth extraction and GBR procedure
- Where
- 4 sites in Poland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Medical Inventi S.A.
Socket Perservation
Clinical Comparison of Xenograft With Hydrogel Versus Xenograft Alone in the Socket Preservation After Tooth Extraction: A Randomized Controlled Clinical Trial
Clinical Comparison of xenograft with hydrogel versus xenograft alone in the socket preservation After tooth extraction: A Randomized controlled Clinical Trial The ideal scaffolds used for alveolar ridge preservation are supposed…
- Trial name
- NCT06957197
- Testing
- Hydrogel with xenograft, Xenograft
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Socket Preservation
Study on Platelet-Rich Fibrin for Preserving Jawbone After Tooth Extraction Using CBCT Imaging in Adults
The goal of this clinical trial is to learn if platelet-rich fibrin (PRF), a substance made from a person's own blood, helps preserve the bone in the jaw after tooth extraction in adults.
- Trial name
- NCT07022860
- Testing
- Platelet-rich fibrin (PRF)
- Where
- Iran
- Volunteers
- 12 people
- Sponsor
- Zahedan University of Medical Sciences
Tooth Loss
Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft
To compare dimensional changes in extraction socket of single rooted teeth, 6 months post extraction, when grafted with xenograft versus allograft.
- Trial name
- PilotXenAllo (NCT04550689)
- Testing
- Bone graft
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- UConn Health
Dry Socket, Postoperative Infections
The Effect of Chlorhexidine + Hyaluronic Acid on Postoperative Wound Healing After Lower Third Molar Removal
Our aim is to evaluate chlorhexidine-hyaluronic acid containing gel on postoperative wound healing regarding impacted lower third molar surgery.
- Trial name
- NCT07044219
- Testing
- Third molar surgery
- Where
- Hungary
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Impacted Mandibular Third Molar Extraction
Hyaluronic Acid Gel After Impacted Mandibular Third Molar Surgery
Surgical removal of impacted lower wisdom teeth can cause pain, facial swelling, difficulty opening the mouth, and discomfort during wound healing.
- Trial name
- NCT07890272
- Testing
- 0.2% Hyaluronic Acid Gel
- Where
- Vietnam
- Volunteers
- 25 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Dental Implant, Tooth Extraction
Soft Tissue Volume Changes After Immediate Implants With Two Different Techniques
The aim is to comparatively evaluate the soft tissue volume changes that occur after tooth extraction and immediate dental implant placement using two different surgical techniques.
- Conditions
- Dental Implant, Tooth Extraction, Bone Resorption
- Trial name
- NCT04803110
- Testing
- Dental implant placement after tooth extraction
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Aula Dental Avanzada
Tooth Extraction, Dental Implantation
Immediate Implant Placement in Fresh Extraction Sockets and Delayed Implants in Healed Sockets.
The purpose of this prospective clinical study was to compare in delayed and immediately placed implants, the marginal vertical bone loss at 4 sides of the implant (buccal, palatal, mesial and distal), as well as the buccal and…
- Conditions
- Tooth Extraction, Dental Implantation, Bone Remodeling
- Trial name
- NCT04346706
- Testing
- Extraction and Implant insertion (test), Implant insertion (control)
- Where
- Lebanon
- Volunteers
- 24 people
- Sponsor
- Saint-Joseph University
Tooth Loss
Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®
The purpose of this study is to clinically, radiographically and histologically evaluate the healing sequence of post-extraction sockets grafted with Bio-Oss Collagen® at 3, 6 and 9 months following tooth extraction in…
- Trial name
- NCT03659617
- Testing
- xenograft (BioOss Collagen)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Stem Cell, Third Molar
Effect of Dental Pulp Stem Cells and L-PRF After Impacted Third Molar Extraction
The purpose of this study is to compare the clinical and radiographic effectiveness of Leukocyte-Platelet Rich Fibrin (L-PRF) and L-PRF combined with dental pulp stem cell (DPSC) application to the extraction socket of mandibular…
- Conditions
- Stem Cell, Third Molar, Periodontal Pocket
- Trial name
- NCT04641533
- Testing
- L-PRF + DPSC, L-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Baskent University
Bone Healing, Implant Stability
ISQ Differences Between Different Implants in Post-extraction Sockets
Two different implants will be used in post-extraction sockets and ISQ will be recorded monthly from insertion moment to 12 months of follow up to understand if ISQ can be affected by implant macro design
- Trial name
- NCT06711744
- Testing
- Implant stability quotient
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
Endodontic Issue, Periodontal Issues
Post-Extraction Healing: microRepair vs Chlorhexidine
This randomized clinical trial evaluates the efficacy of a microRepair ABX mouthwash mousse compared to 0.20% chlorhexidine in promoting wound healing following tooth extraction.
- Trial name
- NCT07555366
- Testing
- microRepair ABX Mousse, CHX mouthwash 0.20%
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Roma La Sapienza
Photodynamic Therapy, Third Molar Extraction
The Effect of Photodynamic Therapy on Post-extraction Third Molar
The extraction of lower third molars is one of the most frequent procedures in oral surgery. For this reason, the extraction of these teeth generally requires a surgical approach involving the elevation of a mucoperiosteal flap…
- Conditions
- Photodynamic Therapy, Third Molar Extraction, Antimicrobial Photodynamic Therapy
- Trial name
- NCT06964178
- Testing
- Experimental: antimicrobial photodynamic therapy (aPDT) after extraction of third molar
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Alveolar Osteitis, Impacted Lower Third Molar
Chlorhexidine Versus Normal Saline Socket Irrigation for Prevention of Dry Socket After Lower Wisdom Tooth Extraction
Dry socket, also called alveolar osteitis, is a painful complication that can occur after tooth extraction, particularly following removal of impacted lower wisdom teeth.
- Trial name
- NCT07814430
- Testing
- Chlorhexidine Socket Irrigation, Normal Saline Socket Irrigation
- Where
- Pakistan
- Volunteers
- 174 people
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Bone Loss
The Use of CoreBone Coral Particles vs. Cones for Preservation of Alveolar Bone
Normally, dentists do not graft the socket after extraction of teeth. When they do graft they use particulate graft devices. The purpose of this study is to examine whether coral particles of 300-450um in comparison to coral…
- Trial name
- CoreBone (NCT02632734)
- Testing
- CoreBone Cone device, CoreBone 500 device
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Socket Preservation
Post Extraction Changes Following Ridge Preservation Using Allogenis Dentin Vs Autogenous Partially Demineralized Dentin
Research question: In patients with unrestorable anterior teeth, will the use of allogenic dentin matrix be more effective than autogenous partially demineralized dentine matrix (APDDM) in reducing hard tissue changes after…
- Trial name
- NCT06477887
- Testing
- Allogeneic Dentin Matrix, Autogenous Partially Demineralized Dentine Matrix
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabete Mellitus
Application of Growth Factors Derived From Platelets to Accelerate Healing and Reduce Post-extraction Complications in Diabetic Individuals
To evaluate soft tissue closure in diabetic extraction sockets using digital scans. To compare healing between sockets treated with Advanced Platelet Rich Fibrin (A-PRF) vs. untreated control sites.
- Trial name
- NCT07287475
- Testing
- Platelet rich fibrin
- Where
- Saudi Arabia
- Volunteers
- 7 people
- Sponsor
- King Abdulaziz University
Post-Extraction Socket Hemostasis, Post-Extraction Socket Pain Relief
Comparison of A-PRF vs Bone Wax in Hemostasis, Pain Relief and Healing Following Exodontia
The goal of this clinical trial is to compare the pain relief and healing effect of A-PRF and Bone-wax in patients having mandibular tooth-extractions.
- Conditions
- Post-Extraction Socket Hemostasis, Post-Extraction Socket Pain Relief, Post-Extraction Socket Healing
- Trial name
- NCT05744726
- Testing
- A-PRF, Bone-wax
- Where
- Pakistan
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Bio-Oss; Mucograft
Bone Volume Changes After Socket Preservation Using Geistlich Bio-Oss Collagen and Mucograft Seal
Evaluation of Bone volume Changes after socket preservation using Geistlich Bio-Oss® Collagen and Geistlich Mucograft® Seal compared to natural healing after tooth extraction
- Trial name
- NCT03395145
- Testing
- Geistlich Bio-Oss® Collagen and Geistlich Mucograft® Seal
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Smoke Exposure
Platelet-Derived Growth Factors to Enhance Healing and Reduce Post-Extraction Complications in Smokers
This study is a randomized controlled clinical trial with a split-mouth design to evaluate the effect of Advanced Platelet-Rich Fibrin (A-PRF) application on socket healing following dental extractions in smokers.
- Trial name
- NCT07364890
- Testing
- A- PRF
- Where
- Saudi Arabia
- Volunteers
- 12 people
- Sponsor
- King Abdulaziz University