Clinical trials: Post-Mastectomy
Breast Cancer
Comparison of Different Volumes Spread of Erector Spinae Block in Post Mastectomy Pain Syndrome Management
Cancer breast is one of the most common tumors among women and surgery is still the key for its management and cure. Post-mastectomy pain control is crucial as acute postoperative pain is a significant factor in the development…
- Trial name
- NCT05192278
- Testing
- erector spinae block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Pain, Postoperative
Perioperative Administration of Pregabalin for Pain After Mastectomy
The investigators hypothesize that pregabalin will decrease post-operative pain scores and analgesic use following total mastectomy compared to placebo.
- Trial name
- NCT00938548
- Testing
- Pregabalin
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Severance Hospital
Postoperative Pain, Breast Cancer
RISS Versus SPSIP Block in Modified Radical Mastectomy
This prospective randomized double-blind controlled trial aims to compare the postoperative analgesic efficacy and dermatomal spread of rhomboid intercostal-subserratus plane (RISS) block and serratus posterior superior…
- Trial name
- RSMRM (NCT07659990)
- Testing
- Rhomboid Intercostal-Subserratus Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ferit Yetik
Pain, Postoperative
Comparison of PECS II Block and Combined Serratus Anterior Plane Block to Reduce Acute Pain After Mastectomy
In this study, PECS II block or CSAB will be applied to patients who have had a modified radical mastectomy under general anesthesia for postoperative pain relief by using 30 ml of 0.25% bupivacaine .All patients will receive…
- Trial name
- NCT05961735
- Testing
- PECS II Block, Combined Serratus Anterior Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Mastectomy, Breast Reconstruction
Evaluation of a Human Acellular Dermal Matrix in Post Mastectomy Reconstruction
Use of a HADM and implant in post-mastectomy breast reconstruction.
- Trial name
- NCT02263261
- Testing
- Flex HD Pliable Perforated HADM
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Musculoskeletal Transplant Foundation
Post Mastectomy
Impact of Proximal Motor Control Exercise on Scapular Muscles Activation Pattern in Breast Cancer Survivors Following Mastectomy
This prospective, single-center, assessor-blinded, parallel-group randomized controlled trial investigated whether adding proximal motor control exercises (PMCE) to conventional physiotherapy treatment (CPT) improved shoulder…
- Trial name
- NCT07103109
- Testing
- Proximal Motor Control exercises, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ahram Canadian University
Breast Cancer, Breast Cancer Female
Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial
The LOLIPOP Trial is a large (n=4,300 patients) pragmatic, international, multicentre, prospective, randomised, double blind, placebo-controlled, parallel assessment, safety and effectiveness superiority study.
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Conserving Surgery, Mastectomy
- Trial name
- LOLIPOP (NCT05072314)
- Testing
- lidocaine 2% and 10%
- Where
- 49 sites in Australia, Hong Kong and 2 more
- Volunteers
- 4,300 people
- Sponsor
- Monash University
Pain, Postoperative
Flexibility of Cognition And Persistent Pain
This observational study aims to determine the association between preoperative cognitive flexibility and the risk of developing PPSP by preoperative administration of cognitive tests.
- Trial name
- FlexCAPP (NCT02579538)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Ketamine, Pecs Block, Topical Wound Instillation , Modefied Radical Mastectomy
Comparative Study of Ketamine Added to Bupivacaine in PECS Block Versus Topical Wound Instillation on Post Operative Analgesia in Modified Radical Mastectomy Surgery
Comparative study of ketamine added to bupivacaine in PECS block versus topical wound instillation on post operative analgesia in modified radical mastectomy surgery
- Trial name
- NCT05410158
- Testing
- Ketamine in PECS block versus topical wound instillation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Mastectomy; Lymphedema
Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Postoperative Pain After Mastectomy
Breast cancer is the most common type of cancer in women. Removal of the breast, called "mastectomy", is performed either when there is cancer-or an increased risk of cancer-in the breast.
- Trial name
- NCT05444361
- Testing
- Cryoneurolysis
- Where
- 5 sites in United States
- Volunteers
- 216 people
- Sponsor
- University of California, San Diego
Lymphedema Arm, Breast Cancer Lymphedema
Preoperative Indocyanine Green Lymphography and High-Frequency Ultrasound as Predictors of Lymphaticovenous Anastomosis Outcome in Post-Mastectomy Upper Limb Lymphedema
This study aims to evaluate the predictive value of preoperative indocyanine green (ICG) lymphography and high-frequency ultrasound in determining the outcomes of lymphaticovenous anastomosis (LVA) in patients with…
- Trial name
- NCT07614815
- Testing
- lymphatic-venous anastamosis
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Local Anesthetic
Infusion of a Local Anaesthetic in the Surgical After Modified Radical Mastectomy With Expander
Background: The use of local anesthetics as a supplement to conventional techniques in breast surgery is widely reported in the literature.
- Trial name
- NCT01389934
- Testing
- levo-bupicaine
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Basque Health Service
Breast Cancer, Lumpectomy
Treatment of Benign Breast Deformities and Post-Segmental Mastectomy Breast Deformities With Autologous Fat Grafting (AFT)
The investigators will assess changes in breast appearance, graft retention and quality of life over one year in patients who have received direct autologous adipose tissue injection for the treatment of objectionable…
- Conditions
- Breast Cancer, Lumpectomy, Mastectomy, Segmental
- Trial name
- NCT01756092
- Testing
- Autologous Fat Graft
- Where
- United States
- Sponsor
- University of Pittsburgh
Dexmedetomidine, Lidocaine
Dexmedetomidine Versus Lidocaine Infusions as Adjuvants to General Anesthesia for Chronic Pain Management After Mastectomy
This study aims to compare dexmedetomidine and lidocaine infusions as adjuvants to general anesthesia for chronic pain management after mastectomy.
- Conditions
- Dexmedetomidine, Lidocaine, Infusion, Adjuvants
- Trial name
- NCT06910644
- Testing
- Dexmedetomidine, Lidocaine, Isotonic saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Lymphedema of Upper Limb
Comparative Effects of KT and PG on UE Lymphedema and Functional Disability After Mastectomy
To compare the effects of Kinesio taping and compression garmets on the upper extremity lymphedema,functional disability and quality of life after mastectomy.
- Trial name
- NCT05762224
- Testing
- Effect of kinesio taping on upper limb lymphedema
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Breast Cancer, Chronic Pain
Persistent Pain After Reconstruction Following Mastectomy
A cross sectional study to determine the prevalence of persistent pain after reconstructive surgery after mastectomy for breast cancer, with a comparative analysis of a cohort treated with mastectomy without reconstruction.
- Trial name
- NCT01738048
- Testing
- Reconstruction
- Where
- Denmark
- Volunteers
- 1,352 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post Operative Pain
Erector Spinae Catheter Versus Paravertebral Catheter for Postoperative Analgesia in Cancer Patients Post Mastectomies
All patients admitted in National Cancer institute, Cairo University for breast surgeries will be investigated for inclusion criteria in the current study.
- Trial name
- NCT05771116
- Testing
- ERECTOR SPINAE PLANE BLOCK and PARAVERTEBRAL BLOCK:, PARAVERTEBRAL BLOCK:
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- National Cancer Institute, Egypt
Breast Cancer
Evaluating Mepitel in Post-mastectomy Patients and the Role of the Skin Microbiome in Radiation Dermatitis
The aim of this study is to examine alterations in the skin microbiome that occur during radiation therapy. The study design will examine changes secondary to ionizing radiation, and correlate these changes with the development…
- Trial name
- NCT03519438
- Testing
- Mepitel
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Seroma, Breast Cancer
Seroma of the Mammary Gland
The study is designed as international, prospective, minimal interventional study in cooperation with EUBREAST e.V. (European Breast Cancer Research Association of Surgical Trialists).
- Conditions
- Seroma, Breast Cancer, Mastectomy, Breast Implant; Complications
- Trial name
- SerMa (NCT05899387)
- Testing
- Swap collection, Seroma punction, Blood sampling
- Where
- Germany
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Augsburg
Mastectomy; Lymphedema, Chronic Pain
Erector Spinae Block Versus Paravertebral Block on Chronic Pain After Mastectomy
The goal of this clinical trial is to learn if the erector spinae block can reduce the incidence of chronic pain compared to the paravertebral block in adult patients undergoing total mastectomy.
- Conditions
- Mastectomy; Lymphedema, Chronic Pain, Regional Anesthesia Morbidity, Opioid Use
- Trial name
- NCT07561411
- Testing
- Paravertebral block, Erector Spinae block
- Where
- Lebanon
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center