Clinical trials: Post-Mastectomy
Post-Mastectomy Neuropathic Pain Syndrome
Serratus Plane Block (SPB) Versus Capsaïcine Versus Botox-A for Chronic Neuropathic Pain in Post-mastectomy Syndrome
The goal of this phase II clinical trial is to study the effectiveness of a treatment with Serratus Plane Block (SPB) or Botox-A in comparison with capsaicin for the control of chronic neuropathic pain of post-mastectomy syndrom…
- Trial name
- SERCABOT (NCT06807164)
- Testing
- Capsaicin 8% Patch, Serratus Plane Block, Botulinum Toxin A
- Where
- France
- Sponsor
- Centre Oscar Lambret
Esketamine and the Quality of Recovery
Esketamine Administration on Recovery Quality After Radical Mastectomy
Some studies have reported that intravenous esketamine reduce postoperative pain intensity. The investigators investigated whether esketamine could improve the the quality of recovery after modified radical mastectomy.
- Trial name
- NCT05289440
- Testing
- Low-dose esketamine infusion, High-dose esketamine infusion, Saline infusion
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Anqing Municipal Hospital
Breast Reconstruction
Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants
The purpose of this study is to evaluate the safety and effectiveness of ARTIA in adult participants undergoing immediate, two-stage, implant-based breast reconstruction post-mastectomy.
- Trial name
- NCT06575192
- Testing
- ARTIA Reconstructive Tissue Matrix
- Where
- 23 sites in United States
- Volunteers
- 264 people
- Sponsor
- AbbVie
Breast Neoplasms, Pain, Postoperative
Persistant Post-mastectomy Pain in Breast Cancer : Incidence and Risk Factors
Post Mastectomy Pain Syndrome (PMPS) is a major complication of breast surgery responsible for depression and disability. The project consists of a prospective cohort on patients going for oncological breast surgery at National…
- Conditions
- Breast Neoplasms, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04676438
- Where
- 2 sites in Morocco
- Volunteers
- 722 people
- Sponsor
- Moroccan Society of Surgery
Breast Cancer
Targeted Pain Coping Skills Training (PCST) for Prevention and Treatment of Persistent Post-Mastectomy Pain
This study looks at whether a coping skills training program can help women manage pain and stress after breast surgery, and lower the risk of developing chronic pain.
- Trial name
- NCT02439437
- Testing
- Psychosocial Intervention
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Duke University
Seroma, Breast Cancer
Seroma of the Mammary Gland
The study is designed as international, prospective, minimal interventional study in cooperation with EUBREAST e.V. (European Breast Cancer Research Association of Surgical Trialists).
- Conditions
- Seroma, Breast Cancer, Mastectomy, Breast Implant; Complications
- Trial name
- SerMa (NCT05899387)
- Testing
- Swap collection, Seroma punction, Blood sampling
- Where
- Germany
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Augsburg
Comparison Between Ultrasound Guided Erector Spinae Plane Block and Para-vertebral Block on Acute and Chronic Post Mastectomy Pain
Comparison Between U\S Guided Erector Spinaeblock and Paravertebral Block on Acute and Chronic Post Mastectomy Pain
compare between ultrasound guided erector spinae plane block and ultrasound guided paravertebral block on acute and chronic post mastectomy pain
- Trial name
- NCT04498234
- Testing
- ultrasound guided erector spinae plane block with bupivacaine 0.25% And ultrasound guided Paraveretebral block with bupivacaine 0.25 %
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- South Egypt Cancer Institute
Analgesia
Open Versus Ultrasound Approach for Serratus Anterior Block
Ultrasound-guided Serratus anterior plane (SAP) block is an interventional technique that recently gained popularity in the context of postoperative analgesia after breast surgery.
- Trial name
- NCT04841564
- Testing
- ultrasound approach of serratus anterior block, open approach of serratus anterior block
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Mansoura University
Mastectomy
Kinesio-Taping and Chest Physiotherapy Program After Mastectomy
The modified radical mastectomy (MRM) is a major surgical approach that necessitates the dissection of axillary lymph nodes. As a result, there is more bleeding and the treatment takes longer time.
- Trial name
- NCT06701591
- Testing
- Kinesiotaping, chest physical therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Breast Cancer
A Trial of 15 Fraction vs 25 Fraction Pencil Beam Scanning Proton Radiotherapy After Mastectomy in Patients Requiring Regional Nodal Irradiation
This is a randomized controlled trial to determine the safety of 15 fraction vs 25 fraction pencil beam scanning proton radiotherapy after mastectomy in patients requiring regional nodal irradiation.
- Trial name
- NCT02783690
- Testing
- Hypofractionation
- Where
- 2 sites in United States
- Volunteers
- 88 people
- Sponsor
- Mayo Clinic
Respiratory; Disorder, Functional, Impaired
Dexamethasone and Respiratory Function After Mastectomy
Preoperative dexamethasone reduces symptoms after different surgical procedures including mastectomy in breast cancer, but the effect in the postoperative respiratory function remains unknown.
- Trial name
- Dexa-mama (NCT02305173)
- Testing
- Intravenous Dexamethasone, intravenous salin water
- Where
- Mexico
- Volunteers
- 120 people
- Sponsor
- Instituto Mexicano del Seguro Social
Ketamine, Pecs Block, Topical Wound Instillation , Modefied Radical Mastectomy
Comparative Study of Ketamine Added to Bupivacaine in PECS Block Versus Topical Wound Instillation on Post Operative Analgesia in Modified Radical Mastectomy Surgery
Comparative study of ketamine added to bupivacaine in PECS block versus topical wound instillation on post operative analgesia in modified radical mastectomy surgery
- Trial name
- NCT05410158
- Testing
- Ketamine in PECS block versus topical wound instillation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Lymphedema, Breast Cancer Stage II
EFFECT OF KINESIO TAPING AND LASER THERAPY IN PATIENT WITH LYMPHEDEMA ON GIRTH MEASUREMENT
find out the difference in the effect of kinesio taping and low level laser therapy on 66 patients with post mastectomy lymphedema as regards the following outcomes: 1.girth measurement between the upper limbs 2.) SPADI 3) hand…
- Trial name
- LYMPHEDEMA (NCT06808178)
- Testing
- Low Level Laser Therapy, kinesio taping
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Beni-Suef University
Breast Cancer
Analgesic Effect to Postoperative Pain After Mastectomy: Ultrasound-guided Serratus Anterior Plane Block
Ultrasound guided serratus anterior plane block may decrease acute postoperative pain and consumption of opioid after mastectomy.
- Trial name
- NCT02483923
- Testing
- Ultrasound guided serratus anterior block with ropivacaine, intravenous PCA only
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Chronic Pain
Prediction of Persistent Post-Mastectomy Pain
Chronic pain is devastating both to individuals and society. In an aging population, surgery is an increasing cause of chronic pain, with rates of persistent post-operative pain ranging from 10-65%.In particular, Persistent…
- Trial name
- NCT02329574
- Where
- United States
- Volunteers
- 259 people
- Sponsor
- Brigham and Women's Hospital
Breast Cancer, Chronic Pain
Persistent Pain After Reconstruction Following Mastectomy
A cross sectional study to determine the prevalence of persistent pain after reconstructive surgery after mastectomy for breast cancer, with a comparative analysis of a cohort treated with mastectomy without reconstruction.
- Trial name
- NCT01738048
- Testing
- Reconstruction
- Where
- Denmark
- Volunteers
- 1,352 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lymphedema of Upper Limb
Different Level of ECSWT in Post Mastectomy Lymphedema
to investigate the effectiveness of different dosages of ECSW in the treatment of post mastectomy lymphedema volume and quality of life (Qol)
- Trial name
- NCT06278298
- Testing
- Shockwave, CDT
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Pain, Postoperative
Perioperative Administration of Pregabalin for Pain After Mastectomy
The investigators hypothesize that pregabalin will decrease post-operative pain scores and analgesic use following total mastectomy compared to placebo.
- Trial name
- NCT00938548
- Testing
- Pregabalin
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Severance Hospital
Post-Mastectomy Chronic Pain Syndrome (Disorder)
Cryoablation for Post Mastectomy Pain Syndrome
This is a prospective, randomized, parallel-group, treatment control trial with cross-over options performed at four sites. The purpose of this study is to assess the efficacy and safety of cryoablation therapy for the treatment…
- Trial name
- NCT03293940
- Testing
- Cryoablation, Therapeutic Peripheral Nerve Block (tPNB) Injection
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Emory University
Breast Cancer
Post-Mastectomy Surveillance to Detect Recurrence in Breast Cancer Patients
Currently, there is no standard recommendation for using imaging studies to check patients for breast cancer recurrence who have been treated with mastectomy.
- Trial name
- NCT02688725
- Testing
- post mastectomy ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Providence Health & Services