Clinical trials: Post-Mastectomy
Post-mastectomy Pain Syndrome
Ultrasound-Guided Serratus Plane Block Vs Paravertebral Block For Chronic Post-mastectomy Pain.
compare the analgesic efficacy between ultrasound paraverbral block and serratus block in post mastectomy pain.
- Trial name
- NCT04317898
- Testing
- serratus plane block by ultra-sound, paravertebral block by ultra-sound
- Volunteers
- 50 people
- Sponsor
- Assiut University
Breast Cancer
Continues Cicatricial Perfusion of Ropivacaine Versus Placebo After Mastectomy : Rehabilitation After Treatment
The acute pain care, in particular after breast cancer surgery must be early and quickly effective, because a severe postoperative pain increases the risk of chronic pain and exposes to a risk of important embarrassment for the…
- Trial name
- NCT02525211
- Testing
- Ropivacaine, physiological saline
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Institut Paoli-Calmettes
Erector Spinae Plane Block
Effect of Adding Dexmedetomidine As Adjuvant to Bupivacaine in US Guided ESPB for Post MRM Pain Management
The aim of the study is to assess the effect of adding dexmedetomidine to bupivacaine in US guided erector spinae plane block in modified radical mastectomy surgeries , Using visual analogue score and post-operative narcotics…
- Trial name
- NCT06022614
- Testing
- Use Bupivacaine 0.25% Injectable Solution, Bupivacaine 0.25% Injectable Solution plus Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abanoub Habib
Breast Cancer
Brass Mesh Bolus in Rotational Post-Mastectomy Radiation Therapy
The hypothesis is that the daily use of brass mesh bolus achieves a comparable dose to every-other-day use of Superflab bolus (current standard of care) in chest wall post-mastectomy patients treated with rotational 6 MV photon…
- Trial name
- NCT05483712
- Testing
- Brass Mesh Bolus
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Nova Scotia Cancer Centre
Mastectomy, Breast
A Bionic Breast Project Using Neuroprosthesis to Reduce Chronic Pain After Mastectomy
This trial seeks to establish whether or not touch sensation can be restored to the breast via neural stimulation. Data will also be obtained to inform future feasibility (including safety), efficacy, and acceptability trials.
- Conditions
- Mastectomy, Breast, Chronic Pain
- Trial name
- NCT06382272
- Testing
- Bionic Breast implant
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Chicago
ESPB, Mg Sulfate,Post Mastectomy
Efficacy of Magnesium Sulfate as an Adjuvant in Erector Spinae Plane Block as an Anesthetic Post Operative After Modified Radical Mastectomy
efficacy of magnesium sulfate as an adjuvant in erector spinae plane block as an anesthetic post-operative after modified radical mastectomy
- Trial name
- NCT05976464
- Testing
- Magnesium sulfate in erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Pain, Chronic Pain
Levobupivacaine Prolonged Wound Infusion for Postoperative Pain Relief After Breast Surgery
The aim of the study is to evaluate efficacy and safety of long term (14 days) wound infusion with levobupivacaine in patients with breast cancer undergoing mastectomy with immediate breast reconstruction: this is a double blind…
- Conditions
- Acute Pain, Chronic Pain, Wound Infusion, Mastectomy
- Trial name
- NCT02035904
- Testing
- Levobupivacaine PCIA (Patient Controlled Intrawound Analgesia), saline, Levobupivacaine continuous infusion
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Pain
Analgesia by Single or Dual Acupoints Stimulation After Radical Mastectomy
The purpose of this study is to compare the effects of dual acupoints and single acupoint transcutaneous electrical acupoint stimulation (TEAS) pretreatment on incidence of Post-Mastectomy Pain Syndrome(PMPS) in patients…
- Trial name
- ASDAS (NCT02741726)
- Testing
- acupoint stimulation, no stimulation
- Where
- 6 sites in China
- Volunteers
- 593 people
- Sponsor
- Zhihong LU
Breast Cancer
Prospective Cohort Study of Local Recurrence After Radical Breast Cancer Resection
The goal of this observational study is to analyze clinicopathological characteristics and identify independent prognostic risk factors, as well as compare treatment outcomes in female patients aged ≥18 years with pathologically…
- Trial name
- NCT07668362
- Testing
- Individualized therapy
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Post Mastectomy Lymphedema
Kinesiology Taping Technique in Post-mastectomy Breast Cancer Related Lymphedema
Generally, Breast cancer related to lymphedema is commonly found in the female population after mastectomy. It has many complications which affects the normal functions of an individual and quality of life.
- Trial name
- NCT05178797
- Testing
- Kinesiology taping technique with exercise therapy, Compression decongestive therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Dow University of Health Sciences
Patients Undergoing Modified Radical Mastectomy
Comparative Study Between the Efficacy of The Serratus Anterior Plane Block and Lumbar Intrathecal Fentanyl Injection for Postoperative Analgesia After Modified Radical Mastectomy
Modified radical mastectomy (MRM) is one of the most common surgeries performed, and one that may be associated with significant acute postoperative pain in breast surgery.
- Trial name
- NCT05352282
- Testing
- Serratus Anterior Plane Block, Lumbar Intrathecal Fentanyl Injection
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Breast Reconstruction Surgery
Tissue Reinforcement for Breast Reconstruction (TRBR) Pivotal Clinical Study (REDEFINE)
The GORE Tissue Reinforcement for Breast Reconstruction (TRBR) research study will look at breast reconstruction during mastectomy procedures.
- Trial name
- NCT06556654
- Testing
- TRBR Device
- Where
- 20 sites in United States
- Volunteers
- 180 people
- Sponsor
- W.L.Gore & Associates
Horner's Syndrome
Horner's SD After Thoracic Epidural Block
This study prospectively evaluates the incidence of Horner's syndrome after thoracic epidural anesthesia following continuous thoracic epidural analgesia for mastectomy.
- Trial name
- NCT02130739
- Testing
- thoracic epidural anesthesia, mastectomy, Ropivacaine
- Where
- South Korea
- Volunteers
- 450 people
- Sponsor
- Soonchunhyang University Hospital
Breast Cancer, Recurrent Disease
Safety of Omitting Axillary Surgery in Breast Cancer Patients With Isolated Chest Wall Recurrence
The axillary management of breast cancer patients with operable isolated chest wall recurrence after mastectomy is unclear. We aim to determine if axillary restaging surgery can be safely omitted with no increased recurrences in…
- Trial name
- NCT06088719
- Testing
- axillary surgery
- Where
- Singapore
- Volunteers
- 300 people
- Sponsor
- KK Women's and Children's Hospital
Serratus Plane Block, Chronic Pain
Serratus Plane Block in Preventing Postoperative Pain of Mastectomy
A prospective, double-blinded randomized controlled, 1-year follow-up study was designed to compare the analgesic effect of serratus plane block (SPB) after breast cancer surgery.
- Conditions
- Serratus Plane Block, Chronic Pain, Breast Cancer
- Trial name
- NCT03615430
- Testing
- serratus plane block with local anesthetic, serratus plane block with saline
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Feng Xia
Mastectomy, Segmental, Regional Anesthesia
Post-discharge Pain After Breast-surgery Treated by Paravertebral Block
Breast surgery is known being associated to a high risk of persistent post-operative pain, which has been related, among other factors, to a poorly treated acute pain.
- Trial name
- NCT03618459
- Testing
- Phone questionnaire
- Where
- Switzerland
- Volunteers
- 244 people
- Sponsor
- Samuele Ceruti
Wound Complication, Surgical Wound Infection
Cosmetic Outcome of Electrocautery, Scalpel and PEAK PlasmaBlade for Surgical Breast Incisions
This study will compare the cosmetic scar result from the use of scalpel, electrocautery, and pulsed electron avalanche knife (PEAK) PlasmaBlade (PPB) for the initial skin incision for total mastectomy procedures without…
- Conditions
- Wound Complication, Surgical Wound Infection, Post-operative Pain, Postoperative Complications
- Trial name
- SCPPB (NCT06191159)
- Testing
- Scalpel and standard electrocautery or PEAK PlasmaBlade, PEAK PlasmaBlade, Standard Electrocautery
- Where
- Canada
- Volunteers
- 186 people
- Sponsor
- University of British Columbia
Post-mastectomy Pain Syndrome
Stellate Ganglion Destruction With Alcohol Versus Thermal Ablation for Chronic Post Mastectomy Pain
Group A: SGB with alcohol injection by ultrasound guidance and C7 level confirmation by fluoroscopy. Group B: Thermal RF; thermal RF neurolysis will be applied with a time of 60 seconds at 80º C, and then will be repeated twice .
- Trial name
- NCT05771103
- Testing
- thermal Radiofrequency neurolysis of Stellate ganglion
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Peripheral Nerve Block Procedure
Prospective Post-market Evaluation of an Echogenic Catheter
Patients scheduled for mastectomy and suitable for paravertebral block will be randomized to one of 2 groups. Group 1 will have the nerve block performed using a standard non-echogenic needle and catheter under ultrasound…
- Trial name
- EchoCath (NCT02136446)
- Testing
- EchoGlo Nerve Block Catheter, Pajunk® Nerve Block Catheter
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Smiths Medical, ASD, Inc.
Breast Cancer
Drain Removal on Postoperative Safety and Patient Satisfaction in R-E-NSM With Prepectoral DIBR
Breast cancer is a malignant tumor that seriously threatens the health of women, with an increasing incidence rate. The current main treatment methods include multidisciplinary diagnosis and treatment such as surgery…
- Trial name
- DRAIN (NCT07237828)
- Testing
- Drain Removal Timing After Endoscopic Breast Reconstruction Surgery
- Where
- China
- Volunteers
- 379 people
- Sponsor
- Du Zhenggui