Clinical trials: Post-Mastectomy
BREAST-Q
Validity and Reliability of Arabic Version of Breast Questionnaire
To test validity and reliability of the translated Arabic version of breast questionnaire .
- Trial name
- NCT05415033
- Testing
- BREAST-Q
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Cancer
Laser Speckle Imaging During Breast Reconstruction
Around 3500 women a year have surgery to reconstruct a breast/s after cancer. Breast reconstruction can have a positive impact on their lives, but unfortunately 3 or 4 in 10 women have problems with healing after their operation.
- Trial name
- SIMBAR (NCT06523452)
- Testing
- Laser Speckle Imaging
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Post Mastectomy Lymphedema
Effect of Thera-Band Versus Swiss Ball Exercises on Postural Stability in Post Mastectomy Lymphedema
The purpose of the study is to determine the effect of Thera-band exercises versus Swiss ball exercises on postural stability in unilateral post mastectomy lymphedema.
- Trial name
- NCT07019311
- Testing
- Thera-Band exercises, Swiss ball exercises, Traditional physical therapy program
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Pulsed Radiofrequency, Shoulder Individual Nerves Brachial Plexus
Pulsed Radiofrequency of Shoulder Individual Nerves Versus Brachial Plexus in Management of Chronic Post Mastectomy Shoulder Pain
this study aims to assess the role of pulsed radiofrequency of the brachial plexus or pulsed radiofrequency of shoulder individual nerves in the management of post-mastectomy shoulder pain.
- Conditions
- Pulsed Radiofrequency, Shoulder Individual Nerves Brachial Plexus, Chronic, Post Mastectomy
- Trial name
- NCT07002944
- Testing
- Brachial plexus pulsed radiofrequency, Sholder individual nerves pulsed radiofrequency, Control
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Other Reconstructive Surgery
Use of Pulsed Electromagnetic Fields (PEMF) After Breast Reconstruction Surgery
Pedicled transverse rectus abdominus myocutaneous (TRAM) flaps are the most common post-mastectomy breast reconstructive surgeries that utilize the patient's tissue.
- Trial name
- NCT01262599
- Testing
- Ivivi Torino II PEMF Device
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Columbia University
Neuropathic Pain, Sensation Disorders
Photobiomodulation on Neuropathic Pain and Sensation Post-mastectomy
The goal of this case study is to examine the effects of Photobiomodulation (PBM) on neuropathic pain and sensation post-mastectomy in one female participant.
- Trial name
- NCT06194136
- Testing
- PBM light therapy
- Where
- United States
- Sponsor
- Tufts University
Neuropathic Pain Induced by Mastectomy
Lidocaine IV Injection With Different Doses for Patients With Neuropathic Pain After Mastectomy
cancer has become the most common malignancy affecting women worldwide, and its incidence is increasing annually. According to the Global Cancer Observatory (GLOBOCAN) 2020 published by the International Agency for Research on…
- Trial name
- NCT07475520
- Testing
- Lidocaine 2%, Lidocaine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Breast Cancer, Postoperative Pain
Comparison of Pre-op and Post-op Pectoralis Nerve Block
The investigators will compare whether patients will have better pain control if they were to receive (PEC I/II block) before surgery or after mastectomy.
- Conditions
- Breast Cancer, Postoperative Pain, Anesthesia, Nerve Block
- Trial name
- NCT03653988
- Testing
- PEC I/II blocks by anesthesiologist - pre-operative, PEC I/II blocks by surgeon - intra-operative
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Melinda Seering
Chronic Postoperative Pain
Preoperative Erector Spinae Plane Block Versus Paravertebral Plane Block in Decreasing Post Mastectomy Pain Syndrome
Breast cancer is considered the commonest malignancy affecting women with an incidence exceeding one million cases per year. Although it has a favorable prognosis with improved lines of treatment, some complications may still…
- Trial name
- NCT06036979
- Testing
- Paravertebral plane block, Erector spinae plane block, Intravenous morphine, ketorlac and paracetamol
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Pain, Breast Diseases
T3AI-Pain After Breast Surgery
Current standard of care for post-operative analgesia after breast surgery in CDHA is Tylenol #3® (300 mg acetaminophen, 30 mg codeine, 15 mg caffeine per tablet).
- Trial name
- T3AI (NCT00299039)
- Testing
- acetaminophen plus codeine, acetaminophen plus ibuprofen
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Nova Scotia Health Authority
Breast Cancer Females
"Topical Tranexamic Acid With Flap Fixation: A Novel Approach to Minimize Post-operative Drainage and Surgical Site Infection in Patients Undergoing Modified Radical Mastectomy"
Seroma (a collection of fluid under the skin) is a common problem after breast cancer surgery, especially after modified radical mastectomy (MRM), where lymph nodes from the armpit are also removed.
- Trial name
- NCT07434453
- Testing
- Tranexamic Acid (Topical Application in Mastectomy Wound), flap fixation
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Noor ul Ain
Stellate Ganglion, Radiofrequency Ablation
Combining Stellate Ganglion and T2 and T3 Radiofrequency Ablation on Post-mastectomy Complex Regional Pain Syndrome
The aim of this study is to evaluate the efficacy of the combination of Ultra Sound (US) guided radiofrequency stellate ganglion block (SGB) and radiofrequency Thoracic Paravertebral block (TPVB) comparing to US-guided SGB or…
- Conditions
- Stellate Ganglion, Radiofrequency Ablation, Complex Regional Pain Syndromes, Mastectomy
- Trial name
- NCT06033456
- Testing
- Radiofrequency stellate ganglion block using ultrasound guidance (SGB), Radiofrequency thoracic (T2, T3) paravertebral block under fluoroscopic guidance (TPVB), Combined radiofrequency of stellate ganglion block plus thoracic T2, T3 paravertebral block
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- National Cancer Institute, Egypt
Breast Cancer, Mastectomy; Lymphedema
Same-Day Discharge After Nipple-sparing Mastectomy or Skin-sparing Mastectomy With Breast Reconstruction
This novel study will assess the feasibility and outcomes of same-day discharge following mastectomy with implant-based pre-pectoral reconstruction.
- Conditions
- Breast Cancer, Mastectomy; Lymphedema, Same Day Surgery, Nipple-sparing Mastectomy
- Trial name
- NCT04596683
- Testing
- Same-day NSM or SSM
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Georgetown University
Acute Post-mastectomy Pain Treatment
Adding Morphine to ESP Block in Management of Acute PMP
The aim of the study is to determine the efficacy of adding morphine in two doses (3mg, 5mg) to erector spinae plane block in relieving acute post mastectomy pain
- Trial name
- NCT06175741
- Testing
- erector spinae plane block
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Breast Reconstruction Following Mastectomy
Does Nerve Grafting Improve Sensation After Nipple-Sparing Mastectomy With Implant Reconstruction?
The goal of this clinical trial is to learn if adding an allogeneic (donor) nerve graft during breast reconstruction can improve recovery of breast and nipple sensation in women undergoing bilateral nipple-sparing mastectomy with…
- Trial name
- NCT07819357
- Testing
- Allogeneic Nerve Grafting
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Endeavor Health
Mastectomy; Lymphedema
Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Postoperative Pain After Mastectomy
Breast cancer is the most common type of cancer in women. Removal of the breast, called "mastectomy", is performed either when there is cancer-or an increased risk of cancer-in the breast.
- Trial name
- NCT05444361
- Testing
- Cryoneurolysis
- Where
- 5 sites in United States
- Volunteers
- 216 people
- Sponsor
- University of California, San Diego
Mammaplasty, Mastectomy
Breast Reconstruction and Augmentation With Brava Enhanced Autologous Fat Micro Grafting
The primary objectives of this study is to determine whether use of a negative pressure external soft-tissue expansion system pre-operatively and post-operatively improves and secures graft survival in autologous fat micro…
- Conditions
- Mammaplasty, Mastectomy, Lumpectomy
- Trial name
- NCT00466765
- Testing
- Brava Autologous Fat Transfer System
- Where
- 2 sites in United States
- Volunteers
- 589 people, healthy volunteers welcome
- Sponsor
- Brava
Locoregional Analgesia in Breast Surgery
Double-blind Study to Assess effectIveness of Pectoral Nerves Block After Breast Surgery on Piritramide Consumption
The aims of this study is to compare the effectiveness of pecs block associated to a general anesthesia in terms of Piritramide consumption compared with a general anaesthesia alone and the chronic pain incidence in patients that…
- Trial name
- DESIGN (NCT02655965)
- Testing
- Ropivacaine, Clonidine, Sodium Chloride
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- Jules Bordet Institute
Implant Based Breast Reconstruction
Post-market Surveillance Study to Evaluate the Quality of Life and the Safety and Effectiveness of the TIGR® Matrix After Reconstructive Breast Surgery
The goal of this observational study is to evaluate the quality of life of participants who have undergone implant-based breast surgery. This will be done using the BREAST-Q questionnaire.
- Trial name
- TIGR-Matrix (NCT06511167)
- Testing
- TIGR® Matrix
- Where
- 5 sites in Germany
- Volunteers
- 135 people
- Sponsor
- AWOgyn
Post Mastectomy
Sensorimotor Training Exercises for Shoulder Position Sense
Forty-six female patients aged 35-55 years who were suffering from shoulder dysfunction following mastectomy surgeries participated in this study.
- Trial name
- NCT07316283
- Testing
- Sensorimotor Training Exercises, Traditional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University