Clinical trials: Post-Op Complication
Post-operative Pain
Intrathecal Opioid Study
This is an interventional drug trail to evaluate the effect of different intrathecal opioids on post-operative pain experiences in women who have undergone caesarean section surgery.
- Trial name
- NCT02577809
- Testing
- Morphine100, Morphine50, Fentanyl
- Where
- South Africa
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Witwatersrand, South Africa
Postoperative Pain, Total Knee Arthroplasty
Comparing ACB+IPACK and ACB+BiFeS Block Combinations for Analgesia in Total Knee Arthroplasty
Total knee arthroplasty (TKA) is associated with severe postoperative pain that delays mobilization, prolongs hospital stay, and reduces patient satisfaction.
- Trial name
- NCT07561333
- Testing
- ACB+IPACK Group, ACB+BiFeS Group
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Hitit University
Chronic Postoperative Pain
Low Dose Peri-operative IV Ketamine for Chronic Post-surgery Pain Prevention
This study will test the null hypothesis that low-dose ketamine given peri-operatively will have no effect on the development of chronic post-surgical pain, in patients undergoing thoracotomy or video assisted thoracic surgery…
- Trial name
- NCT01296347
- Testing
- Ketamine
- Where
- United Kingdom
- Volunteers
- 77 people
- Sponsor
- Imperial College Healthcare NHS Trust
Pain, Postoperative
Transversus Abdominis Plane Block and Quadratus Lumborum Block in Pediatric Patients
In the pediatric age group, postoperative pain is very important for the children to have a comfortable and problem-free postoperative period.
- Trial name
- NCT04209478
- Testing
- Tramadol hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Pain, Postoperative
Comaprison Between QLB and ESPB in Patients for PCNL Operation
comparing the subcostal oblique Quadratus Lumborum block and the Erector Spinae plane block in patients undergoing percutaneous nephrolithotomy operation to get the best and longest postoperative analgesic effect.
- Trial name
- NCT04277611
- Testing
- Subcostal Oblique Quadratus Lumborum Block and Erector Spinae Plain Block.
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Assiut University
Surgical Wound Infection
48 Hours After Surgery Shower Patient's Wound Infection Rate, Pain Score, Patient Satisfaction and Cost.
Background and Purpose:The level of the surgical wound healing of the epidermis takes 6-12 hours, and the peak period of 48 hours to achieve healing.The traditional postoperative wound care was every 1-3 days clean with saline…
- Trial name
- NCT01846598
- Where
- Taiwan
- Volunteers
- 444 people
- Sponsor
- National Taiwan University Hospital
Neoplasms Malignant, Rectal Cancer
Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection
The goal of this clinical trial is to compare the efficacy of using polypropylene mesh for hernia prevention after stoma closure in patients with colorectal cancer and non-mesh repair.
- Conditions
- Neoplasms Malignant, Rectal Cancer, Hernia Incisional, Surgery
- Trial name
- ProMeLAR (NCT05939687)
- Testing
- mesh, non-mesh
- Where
- Russia
- Volunteers
- 142 people
- Sponsor
- Blokhin's Russian Cancer Research Center
Post Operative Delirium, Post Operative Pain
Peritonsillar Bupivacaine Infiltration After Tonsillectomy In Children
To evaluate the effect of peritonsillar bupivacaine infiltration on the development of postoperative delirium in pediatric patients undergoing tonsillectomy or adenotonsillectomy.
- Trial name
- NCT06863714
- Testing
- peritonsillar bupivacaine injection
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Gallstone Disease, Gallstone; Colic
A Randomized Controlled Trial Comparing Fat-free Versus Balanced (WHO) Diet in Gallstone Disease
The goal of this trial is to assess the effect on the quality of life (QoL) of recommending a fat-free diet versus a balanced WHO diet in symptomatic patients with gallstones and in patients undergoing cholecystectomy for…
- Conditions
- Gallstone Disease, Gallstone; Colic, Gallstone; Cholecystitis, Acute, Cholelithiases
- Trial name
- RADIGAL (NCT06405906)
- Testing
- Fat-free diet, Balanced WHO diet
- Where
- Greece
- Volunteers
- 242 people
- Sponsor
- University Hospital of Crete
Surgical Site Infections
PVP Iodine vs Chlorhexidine in Alcohol for Disinfection of the Surgical Site
Prospective cluster-randomized multicenter cross-over trial to prove non-inferiority of PI compared to CHX in preoperative skin antisepsis
- Trial name
- PICASSo (NCT03685604)
- Testing
- CHX disinfection, PI Disinfection
- Where
- 3 sites in Switzerland
- Volunteers
- 3,321 people
- Sponsor
- University Hospital, Basel, Switzerland
Diaphragm Injury, Postoperative Complications
High Flow Nasal Cannula and Diaphragmatic Function
Prospective randomized study investigating the effect of postoperative oxygen delivery on diaphragmatic function. Two different modalities of oxygen delivery will be compared: high flow nasal cannula versus standard oxygen…
- Trial name
- NCT05532033
- Testing
- High flow nasal cannula, Facial mask
- Where
- Italy
- Volunteers
- 116 people
- Sponsor
- Università degli Studi di Ferrara
Post Operative Pain
Study to Compare Reduction in Pain After Surgery With and Without Local Anesthesia During Laparoscopy
This study will help to answer the question, "Does injecting local anesthetic before laparoscopic instrument ports are placed decrease pain after surgery?" Patients participating will be randomly assigned to receive local…
- Trial name
- NCT01452633
- Testing
- 0.25% bupivicaine will be injected at the study port site prior to incision, Saline will be injected at the study port site prior to incision, Saline will be in injected into the port site prior to closure
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Cognitive Decline, Urinary Bladder Cancer
Association of POCD With Circulating Biomarkers in Patients Undergoing TUR of Bladder Tumor
Bladder tumor is one of the most widespread tumors in the world, with increasing prevalence at the global level. One of the procedures in patients with bladder tumors is transurethral resection of the bladder (TURM) most often…
- Conditions
- Cognitive Decline, Urinary Bladder Cancer, Frail, Biomarker
- Trial name
- NCT07165236
- Where
- Croatia
- Volunteers
- 42 people
- Sponsor
- Osijek University Hospital
Hypotension
PeRsonalized Blood prEssure Management on Postoperative Complications and Mortality in hIgh-risk Patients Undergoing Major Non-cardiac Surgery
High-risk populations, particularly elderly individuals and patients with cardiovascular comorbidities, exhibit markedly elevated incidences of postoperative myocardial injury (MINS), acute kidney injury (AKI), and mortality.
- Trial name
- PREMIUM (NCT06952387)
- Testing
- Personalized blood pressure management, Routine blood pressure management
- Where
- 7 sites in China
- Volunteers
- 1,624 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Rectal Cancer, Low Anterior Resection Syndrome
Percutaneous Tibial Nerve Stimulation in the Treatment of Anterior Resection Syndrome After Rectal Cancer Surgery
The study aims to evaluate the efficacy of percutaneous tibial nerve stimulation (PTNS) associated with conservative therapy (arm A) for the treatment of low anterior resection syndrome (LARS) compared with only conservative…
- Trial name
- NCT02177084
- Testing
- PTNS
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Necrotic Pulp With Symptomatic Apical Periodontitis
Assessment of Postoperative Pain After Using Two Formulations of Calcium Hydroxide Intracanal Medication .
Calcium hydroxide is advocated as an intracanal medication for various purposes, including prevention of post-treatment symptoms.
- Trial name
- NCT05021809
- Testing
- Calcium hydroxide intracanal medication application
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Postoperative Pain
Adjuvants With Intrathecal Bupivacaine for Postoperative Analgesia
The aim of this study is to compare the postoperative analgesic effect of intrathecal dexmedetomidine combined with bupivacaine and midazolam combined with bupivacaine in high tibial osteotomy.
- Trial name
- NCT06082232
- Testing
- Dexmedetomidine, Midazolam, Bupivacain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anastomotic Leak
Predictors of Intestinal Anastomosis Leakage, Application of New Predictors and New Scores
Aim of the work This study aims at; Early detection of disruption and leakage of intestinal anastomotic sites whether small or large intestine by using biochemical markers as predictors and indicators of leakage with application…
- Trial name
- NCT04422106
- Testing
- Predictors of intestinal anastomosis leakage, application of new predictors and new scores
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Mansoura University
Incisional Hernia
Incisional Hernia Repair With Mesh at Waitemata District Health Board - A 15 Year Retrospective Cohort Study'
A retrospective review of all incisional hernia repairs at North Shore Hospital (NSH), Auckland, NZ was performed between January 2004 and July 2019.
- Trial name
- NCT05482139
- Testing
- Incisional hernia repair with mesh
- Volunteers
- 718 people
- Sponsor
- Waitemata District Health Board
the Incidence of Complications Related to Rectal Anastomosis After Neoadjuvant Therapy
Extended Resection for Rectal Cancer With Neoadjuvant Radiotherapy
Preoperative neoadjuvant therapy has become the guideline-recommended standard treatment for patients with locally advanced or mid-to-low rectal cancer with suspected regional lymph node metastasis.
- Trial name
- NCT05267275
- Testing
- extended resection with splenic flexure mobilization
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Qilu Hospital of Shandong University