Clinical trials: Post-Operative Atrial Fibrillation
Atrial Fibrillation
Human Amniotic Membrane to Decrease Post Operative Atrial Fibrillation
This study will evaluate the application of hAM at the time of cardiac surgery to decrease inflammation and the subsequent substrate to reduce incidence of post-operative atrial fibrillation.
- Trial name
- NCT04130061
- Testing
- Human Amniotic Membrane
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Utah
Lung Cancer, Atrial Fibrillation
PREvention of Atrial Fibrillation in patientS Undergoing thorAcic surGEry for Lung Cancer
The aim of this study is to assess whether prophylactic treatment with metoprolol or losartan is able to reduce the incidence of atrial fibrillation (AF) in patients undergoing thoracic surgery for lung cancer, showing elevated…
- Trial name
- PRESAGE (NCT01281787)
- Testing
- Metoprolol, Losartan
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- European Institute of Oncology
Atrial Fibrillation, Postoperative, Postoperative Complications
Transcutaneous Autonomic Modulation in Thoracic Surgery
In this study, the investigators aim to determine whether non-invasive autonomic modulation decreases inflammation and complications after thoracic surgery.
- Conditions
- Atrial Fibrillation, Postoperative, Postoperative Complications, Inflammation
- Trial name
- TON-POINTS (NCT02783157)
- Testing
- Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Duke University
Atrial Fibrillation Rapid, Postoperative Complications
Preoperative Carbohydrate Load and Intraoperative w3-PUFA in CAGB Surgery
Omega-3 polyunsaturated fatty acids (w-3-PUFA) may have a potential role in enhance the postoperative balance of host immunity and reduce the incidence of postoperative atrial fibrillation (POAF).
- Trial name
- NCT03017001
- Testing
- CHO (carbohydrate), intravenous w-3 PUFA, CHO (carbohydrate) plus intravenous w3-PUFA
- Volunteers
- 60 people
- Sponsor
- Federal University of Mato Grosso
Post Operative Atrial Fibrillation
Evaluation and Monitoring of the Protocol Post Operative Atrial Fibrillation
Objectives The aims of this study is to evaluate the efficacy and tolerance of our post-operative AF management protocol after cardiac surgery, including beta-blockers, digoxin, amiodarone.
- Trial name
- ETOFIB (NCT05165862)
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Brest
Post Operative Arrythmia
Impact of Ligament of Marshall Resection on Atrial Fibrillation Occurrence in Patients Undergoing Coronary Artery Bypass Grafting: A Randomized Controlled Trial
Background: 20-40% of patients with ischemic heart disease managed with coronary artery bypass grafting (CABG) surgeries face the risk of postoperative atrial fibrillation (POAF), which is a known hazardous outcome.
- Trial name
- NCT07492901
- Testing
- A standard on-pump coronary artery bypass grafting (ON-CAB), adjunctive LoM resection
- Where
- 2 sites in Egypt
- Volunteers
- 220 people
- Sponsor
- Kasr El Aini Hospital
Valve Heart Disease, Coronary Artery Disease
Post-Operative Myocardial Incident & Atrial Fibrillation
To explore predictors of major cardio-vascular events after cardiac surgery and trans-catheter valve implantation with a specific interest in studying mechanisms linking pre-operative leukocyte, fat and myocardial phenotypes with…
- Trial name
- POMI-AF (NCT03376165)
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Lille
Atrial Fibrillation
Effect of Venous Cannulation on the Incidence of Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass
Context Atrial fibrillation is the most frequent arrhythmia following coronary artery bypass grafting. POAF is associated with worse outcomes following CABG.
- Trial name
- NCT04641611
- Testing
- Bicaval cannulation, Cavoatrial cannulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Dr. Jean-Francois Morin
Atrial Fibrillation
Postoperative Atrial Fibrillation Suppression By Nerve Stimulation
The current study will evaluate the potential of stimulating the R.auricularis of the vagus nerve located at the Fossa triangularis to ameliorate or suppress AF in the study Population!
- Trial name
- NCT03533140
- Testing
- DUCEST Neurostimulator V Group A, DUCEST Neurostimulator V Group B
- Volunteers
- 42 people
- Sponsor
- Medical University of Vienna
Atrial Fibrillation
Estimation of Average and Beat-to-beat Heart Rate With a Novel Wrist-worn PPG Device in Surgery Patients
The aim of the study is to the reliability and feasibility of a novel optical heart rate monitor in hospital patients. Especially patients with atrial fibrillation are included.
- Trial name
- NCT03081793
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Tampere University Hospital
Post-operative Atrial Fibrillation
Postoperative Atrial Fibrillation in Cardiac Surgery
This multicenter observational study aims to investigate the incidence and identify risk factors associated with postoperative atrial fibrillation (POAF) in patients undergoing cardiac surgery at three medical centers in…
- Trial name
- POAF (NCT06958029)
- Testing
- Cardiac surgery
- Where
- Thailand
- Volunteers
- 275 people
- Sponsor
- Khon Kaen University
Anticoagulant-induced Bleeding, Dental Diseases
Intra- and Post- Operative Bleeding After Simple Dental Extraction in Direct Oral Anticoagulant Therapy
Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral…
- Trial name
- NOADB (NCT03124030)
- Testing
- simple dental extraction
- Where
- Italy
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Atrial Fibrillation, Catheter Ablation
Electroacupuncture Intervention in Catheter Ablation of Atrial Fibrillation
This is a randomized control trial to determine whether electroacupuncture(EA) intervention with Morphine can reduce the intraoperative pain and early post-operative complications in patients undergoing catheter ablation of…
- Trial name
- NCT05575544
- Testing
- Acupuncture plus morphine
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital
CABG, Atrial Fibrillation (AF)
Drainage Technique in CABG
aims to compare the efficacy of the posterior pericardial window versus retro-cardiac drain in preventing postoperative atrial fibrillation and pericardial complications following CABG, while assessing their impact on hospital…
- Trial name
- NCT07194798
- Volunteers
- 122 people
- Sponsor
- Assiut University
Cardiothoracic Surgery, Post-operative Atrial Fibrillation
Intensive Statin Therapy Effect on Post-Operative Atrial Fibrillation (POAF)
This study will compare the effects of 20 mg of atorvastatin to 80 mg of atorvastatin for the prevention of atrial fibrillation after cardiothoracic surgery.
- Trial name
- NCT02029534
- Testing
- Atorvastatin 20 mg, Atorvastatin 80 mg
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Creighton University
Atrial Fibrillation New Onset
Peri-Operative Magnesium Infusion to Prevent Atrial Fibrillation Evaluated.
Post-operative atrial fibrillation (POAF) is commonly observed in patients post cardiac surgery without a previous history of atrial fibrillation (AF) or other arrythmias.
- Trial name
- POMPAE (NCT05669417)
- Testing
- Magnesium sulfate
- Where
- Netherlands
- Volunteers
- 265 people
- Sponsor
- HagaZiekenhuis
Atrial Fibrillation New Onset, Postoperative Cardiovascular Complications
Intelligent Monitoring to Predict Atrial Fibrillation
Atrial Fibrillation (AF) is the commonest arrhythmia worldwide, affects 5% of people over the age of 65 and increases the risk of stroke and heart failure.
- Conditions
- Atrial Fibrillation New Onset, Postoperative Cardiovascular Complications, Atrial Fibrillation
- Trial name
- NOTE-AF (NCT06600620)
- Testing
- Monitoring patients heart rythms with a wireless patch device
- Where
- 2 sites in United Kingdom
- Volunteers
- 1,200 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Atrial Fibrillation
Home Monitoring for Thoracic Surgery Patients
Background and Importance: When patients transition from hospital to home following surgery, perceived complications or poorly controlled pain can result in emergency department visits and readmissions.
- Trial name
- NCT04340960
- Testing
- Home Monitoring
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Western University, Canada
Pulmonary Embolism, Atrial Fibrillation
Study to Find Out the Appropriate Initial Dose of the Anticoagulant Drug Phenprocoumon
Oral anticoagulation is often initiated in hospitalized patients. Although the therapeutic range of phenprocoumon is narrow, the individual drug demands unfortunately vary greatly between persons.
- Conditions
- Pulmonary Embolism, Atrial Fibrillation, Hip Replacement Postoperative, Knee Replacement Postoperative
- Trial name
- NCT00586287
- Testing
- Algorithm for phenprocoumon, Phenprocoumon
- Where
- Switzerland
- Volunteers
- 302 people
- Sponsor
- Cantonal Hospital of St. Gallen
Atrial Fibrillation
The Safety of Non-vitamin K Oral Anticoagulants Compared to Warfarin Early After Cardiac Surgery
A small pilot study comparing different blood thinners (non-vitamin K oral anticoagulants [NOACs] and warfarin) will be conducted in people at risk for blood clots after open-heart surgery.
- Trial name
- NCT05006287
- Testing
- Non-vitamin K oral anticoagulants (NOACs), Warfarin
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- St. Paul's Hospital, Canada