Clinical trials: Post-Operative Atrial Fibrillation
Post-operative Atrial Fibrillation (POAF)
Pilot-Tart Cherry, Mitral Transcriptome, and POAF Incidence
Assess impact of Tart Cherry Concentrate in cardiac surgical patients on POAF and related clinical and economic outcomes. Measure inflammation gene transcripts in cardiac tissue.
- Trial name
- NCT03793465
- Testing
- tart cherry concentrate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Mitral Regurgitation, Computed Tomography
Atrial Fibrillation Risk After Miniinvasive Mitral Valve Repair
This retrospective cohort study investigates how CT-derived tissue quality parameters, serving as markers of metabolic status, predict post-operative atrial fibrillation risk in patients undergoing minimally invasive mitral valve…
- Conditions
- Mitral Regurgitation, Computed Tomography, Atrial Fibrillation
- Trial name
- NCT06707506
- Volunteers
- 114 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Esophagectomy, Pneumonectomy
Stellate Ganglion Block
The purpose of this study is to determine if the addition of an ultrasound guided left sided stellate ganglion block with bupivacaine in patients undergoing esophagectomy, pneumonectomy, or lobectomy will result in lower rates of…
- Conditions
- Esophagectomy, Pneumonectomy, Lobectomy
- Trial name
- NCT06271707
- Testing
- 0.5% bupivacaine, Saline
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Minnesota
Atrial Fibrillation (AF), Hypomagnesemia
Postoperative Incidence of Atrial Fibrillation Following Cardiac Surgery
Introduction: Postoperative atrial fibrillation is one of the most frequent complications in cardiac surgery, with an expected incidence of more than 50% following valve surgery.
- Conditions
- Atrial Fibrillation (AF), Hypomagnesemia, Cardiac Surgery
- Trial name
- NCT06855550
- Where
- Colombia
- Volunteers
- 435 people
- Sponsor
- Fundación Cardioinfantil Instituto de Cardiología
Chronic Coronary Syndrome, Atrial Fibrillation
SGLT2 Inhibitor TrEatment iN Patients Awaiting cOronary arTery bYpass Surgery to Reduce Post-opErative AF
The goal of this randomized, double-blinded, controlled clinical trial is to investigate if treatment with an sodium-glucose cotransporter-2 inhibitor (SGLT2) during the unique time window before coronary artery bypass surgery…
- Trial name
- STENOTYPE (NCT05852704)
- Testing
- Dapagliflozin 10mg Tab
- Where
- 8 sites in Czechia, Denmark and 1 more
- Volunteers
- 800 people
- Sponsor
- Region Örebro County
Post-operative Atrial Fibrillation, CABG
Empagliflozin to Prevent Post-Operative Atrial Fibrillation
This is an interventional, double-blind, placebo controlled, multicenter, randomized clinical trial with allocation sequence concealment and blinded endpoint adjudication.
- Trial name
- EMPOAF (NCT06124937)
- Testing
- Empagliflozin 10 MG
- Where
- 2 sites in Iran
- Volunteers
- 492 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
Heart Diseases, Atrial Fibrillation
Clinical Value of Remote Ischemic Preconditioning
Objectives: Despite utilization of available means for cardioprotection during cardiac surgery, myocardial injury still occurs. Further improvement of cardioprotection is therefore necessary.
- Trial name
- NCT01740102
- Testing
- RIPC
- Where
- Norway
- Volunteers
- 92 people
- Sponsor
- Norwegian University of Science and Technology
Postoperative Delirium (POD), Postoperative Bleeding
GENECARD - the Use of Genetic, Epigenetic, Metabolomic, Proteomic and Microbiotic Markers, Image and Voice Biomarker Analyses, and Pre- and Intraoperative Clinical Data - to Predict Early Complications After Cardiac Surgery.
The goal of this observational cohort study is to prove whether genetic, epigenetic, transcriptomic, proteomic, metabolomic, imaging, voice, and clinical markers can improve prediction of early complications after cardiac surgery…
- Conditions
- Postoperative Delirium (POD), Postoperative Bleeding, Acute Kidney Injury, Atrial Fibrillation (AF)
- Trial name
- GENECARD (NCT07345403)
- Testing
- Multi-Omics Data and Clinical Data Collection
- Where
- Poland
- Volunteers
- 3,000 people
- Sponsor
- Medical University of Gdansk
Lung Cancer, Atrial Fibrillation
Continuous Ambulatory ECG Monitoring for Detection of Postoperative Atrial Fibrillation Following Thoracic Surgery
Atrial fibrillation (AF) is a common and serious complication after lung resection. The incidence is likely underestimated, and risk may persist after leaving hospital.
- Trial name
- NCT04325269
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Manitoba
Atrial Fibrillation
Study of T3 on the Incidence of Atrial Fibrillation in Patients Undergoing Cardiac Surgery
The purpose of this project is to see whether treatment with a thyroid hormone, called triiodothyronine or T3, following open heart surgery reduces the risk of developing atrial fibrillation.
- Trial name
- NCT00289367
- Testing
- Triiodothyronine
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Northwell Health
Atrial Fibrillation
Temporary Autonomic Blockade to Prevent Atrial Fibrillation After Cardiac Surgery
In this study, the investigators aim to determine whether injecting botulinum toxin into epicardial fat pads is efficacious and safe for decreasing postoperative atrial fibrillation (POAF) after cardiac surgery.
- Trial name
- NCT02498769
- Testing
- Botulinum Toxin Type A
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Joseph Mathew, M.D.
Atrial Fibrillation, Atrial Fibrillation, Persistent
Electrical Cardioversion As a Predictor in Postoperative Preservation of Sinus Rhythm
The aim of this study is to evaluate benefits of electric cardioversion in the early and long-term postoperative period in patients after radiofrequency catheter isolation of pulmonary veins.
- Trial name
- NCT06654401
- Testing
- Transthoracic echocardiography, 24-hour ECG Monitor, Electroanatomic mapping
- Where
- Russia
- Volunteers
- 125 people
- Sponsor
- Saint Petersburg State University, Russia
Disorder; Heart, Functional, Postoperative, Cardiac Surgery, Cardiac Insufficiency Following Cardiac Surgery
Statin Therapy In Atrial Refractoriness and Reperfusion Injury
Patients with coronary artery disease are often prescribed drugs called statins because research has shown that, by lowering cholesterol, they reduce the risk of having a heart attack or other complications in the long-term.
- Conditions
- Disorder; Heart, Functional, Postoperative, Cardiac Surgery, Cardiac Insufficiency Following Cardiac Surgery, Atrial Fibrillation, Ischaemia-reperfusion Injury
- Trial name
- STARR (NCT01780740)
- Testing
- Atorvastatin
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Oxford
Atrial Fibrillation New Onset
A Pharmaco-surgical Approach to Reduce Postoperative Atrial Fibrillation After Cardiac Surgery
Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery with an estimated incidence around 35%.
- Trial name
- NCT05780320
- Testing
- Prophylactic amiodarone and posterior pericardiotomy
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Massachusetts General Hospital
Atrial Fibrillation New Onset
Evaluation Of New Onset Postoperative Atrial Fibrillation
This is a multi-center, prospective, randomized and controlled clinical trial comparing the safety and efficacy of the CorMatrix ECM for Pericardial Closure to reduce the incidence of new onset postoperative atrial fibrillation…
- Trial name
- NCT01247974
- Testing
- CorMatrix ECM for Pericardial Closure
- Where
- 16 sites in United States
- Volunteers
- 439 people
- Sponsor
- Elutia Inc.
Atrial Fibrillation
Treatment of Postoperative Atrial Fibrillation - Comparison of Amiodarone and Placebo.
Post-operative atrial fibrillation (POAF) is the most common complication encountered after cardiac surgery; reports show POAF to occur in ~ 35% of patients after CABG.
- Trial name
- NCT02715687
- Testing
- Amiodarone
- Volunteers
- 400 people
- Sponsor
- Rambam Health Care Campus
Atrial Fibrillation (AF), Cardiac Events
Prevention of Atrial Fibrillation After Cardiac Surgery by Pericardiotomy
PRINCE-CH is a multicentre, randomized controlled trial which evaluates the effectiveness and safety of posterior pericardiotomy in preventing POAF after cardiac surgery in Chinese population.
- Conditions
- Atrial Fibrillation (AF), Cardiac Events, Pericardial Effusion
- Trial name
- PRINCE-CH (NCT06728826)
- Testing
- Posterior pericardiotomy
- Where
- China
- Volunteers
- 650 people
- Sponsor
- Changhai Hospital
AKI, Neurocognitive Disorders
El DORADO STUDY (Evaluation of Delivery of Oxygen on Renal, Arrhythmia and Delirium Outcomes Study)
The study aims to develop a novel perioperative noninvasive delivery of oxygen (DO2) and hemodynamic index in the prediction of postoperative outcomes including post-operative acute kidney injury (POAKI), perioperative…
- Conditions
- AKI, Neurocognitive Disorders, Atrial Fibrillation
- Trial name
- NCT04895384
- Testing
- Edwards ClearSight and Masimo SET
- Where
- 2 sites in Singapore
- Volunteers
- 600 people
- Sponsor
- National University Hospital, Singapore
Coronary Artery Disease, Atrial Fibrillation New Onset
Effect of Left Posterior Pericardiotomy for the Prevention of POAF
This study is planned to evaluate the effect of left posterior pericardiotomy for the prevention of postoperative atrial fibrillation after coronary artery bypass grafting.
- Conditions
- Coronary Artery Disease, Atrial Fibrillation New Onset, Pericardial Effusion
- Trial name
- ELIMINATE-AF (NCT06159985)
- Testing
- left posterior pericardiostomy
- Where
- South Korea
- Volunteers
- 270 people
- Sponsor
- Seoul National University Hospital
Atrial Fibrillation
Tragus Stimulation to Prevent Atrial Fibrillation After Cardiac Surgery
Patients undergoing cardiac surgery, specifically a coronary artery bypass graft and/or heart valve replacement surgery, are at a higher risk for post-procedure atrial fibrillation (AF).
- Trial name
- TraP-AF (NCT03392649)
- Testing
- Parasym
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of Chicago