Clinical trials: Post-Operative Complications
Disorder; Mental, Sedative, Pain, Postoperative
Comparison of Hemodynamics Between Dexmedetomidine and Propofol for Sedation in Patients With Abdominal Surgery
This is a single-blind randomized clinical trial. Patients undergoing abdominal tumor surgery were recruited to participate in the study.
- Conditions
- Disorder; Mental, Sedative, Pain, Postoperative, Surgery
- Trial name
- NCT02393066
- Testing
- Propofol, Dexmedetomidine
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Wound Healing and Prevention, Oral Inflammation
Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation.
- Conditions
- Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management
- Trial name
- NCT07095556
- Testing
- Low-level laser therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Postoperative Pain, Postoperative Nausea
Postoperative Pain Control Following Hysteroscopy
Intraoperative lidocaine infusion is a frequently preferred method in surgical procedures due to its reducing the need for opioids, providing better postoperative pain control, reducing postoperative nausea and vomiting and…
- Conditions
- Postoperative Pain, Postoperative Nausea, Analgesia
- Trial name
- NCT06423456
- Testing
- Lidocaine IV, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Reperfusion Injury
Effect of Pneumoperitoneum on Human Ovary
Laparoscopic surgery has played a pivotal role in all surgical fields in modern medicine. It has some well known advantages over open surgery.
- Trial name
- NCT02731651
- Testing
- open hysterectomy, laparoscopic assisted vaginal hysterectomy
- Volunteers
- 20 people
- Sponsor
- Ege University
Postoperative Bleeding, Patient Satisfaction
Reducing Postoperative Bleeding After Hysterectomy Via Independent Closure of Vaginal Cuff Angles
The investigators propose prospectively evaluating if adding separate sutures to the angles of the vaginal cuff before running barbed suture reduces the incidence of patient's perception of bleeding after surgery.
- Conditions
- Postoperative Bleeding, Patient Satisfaction, Complications, Operative Time
- Trial name
- NCT05174988
- Testing
- Angle stitch
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Fluid Overload, Postoperative Complications
Crystalloids Versus Colloids During Surgery
The purpose of the study is to test whether colloid-based goal-directed intraoperative fluid management leads to less perioperative morbidity compared to crystalloid-based goal-directed intraoperative fluid management.
- Trial name
- CC (NCT00517127)
- Testing
- Lactated Ringer's Solution, Hydroxyethylstarch 6% 130/0.4
- Where
- Austria
- Volunteers
- 1,109 people
- Sponsor
- Medical University of Vienna
Anesthesiology, General Surgery
The Effect of Enhanced Recovery After Surgery (ERAS) in Gastric Cancer Surgery
The investigators aimed to clarify the clinical relevance of the ERAS protocol by evaluating the perioperative course in patients undergoing laparoscopic gastric cancer surgery.
- Trial name
- NCT06209983
- Testing
- ERAS, Conventional care
- Where
- Taiwan
- Volunteers
- 38 people
- Sponsor
- National Taiwan University Hospital
Radius Fracture Distal, Pain, Postoperative
Auricular Acupuncture As Part Of A Multimodal Regimen After Distal Radius Open Reduction and Internal Fixation
This randomized controlled trial will test the hypothesis that patients receiving an intraoperative auricular acupuncture protocol will require less postoperative opioid analgesic use compared to those who do not receive…
- Trial name
- NCT05974254
- Testing
- Acupuncture
- Where
- United States
- Sponsor
- Baylor College of Medicine
Postoperative Pain, Shoulder Pain
Comparative Efficacy of Buprenorphine Transdermal Patch Versus Tramadol in Postoperative Analgesia for Shoulder Arthroscopy
This study compares the efficacy, safety, and patient satisfaction of the Buprenorphine 10 mg transdermal patch versus Tramadol for postoperative analgesia in shoulder arthroscopic surgery.
- Conditions
- Postoperative Pain, Shoulder Pain, Opioid Analgesia, Tramadol
- Trial name
- NCT06742554
- Testing
- Buprenorphine transdermal patch, Tramadol
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- medina medical center
Postoperative Pain, Postoperative Analgesia
Serratus Posterior Superior Intercostal Plane Block for Analgesia in Off-Pump Minimally Invasive CABG
Postoperative pain after cardiac surgery is commonly moderate to severe due to sternotomy, thoracotomy, internal mammary artery harvesting, and chest tube placement, and may contribute to adverse systemic and pulmonary outcomes…
- Trial name
- CABG (NCT07412522)
- Testing
- Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Bupivacaine, Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kartal Kosuyolu High Speciality Training and Research Hospital
Postoperative Pain
Combined Intrathecal Morphine and Dexmedetomidine Analgesia
The current study investigated the effect of adding dexmedetomidine to intrathecal morphine for postoperative analgesia in cancer patients undergoing major abdominal surgery.
- Trial name
- ITMandDEX (NCT02435537)
- Testing
- Dexmedetomidine (Precedex), Bupivacaine, Morphine
- Volunteers
- 90 people
- Sponsor
- Assiut University
Postoperative Pulmonary Complications
Mechanical Power and Driving Pressure Exposure in Laparoscopic Surgery
Postoperative pulmonary complications (PPCs) remain an important cause of morbidity after abdominal surgery. Intraoperative mechanical ventilation may contribute to lung injury through the mechanical load applied to the…
- Trial name
- NCT07431242
- Testing
- Intraoperative Ventilatory Load Exposure (Mechanical Power and Driving Pressure)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istinye University
Postoperative Pain
Comparison of Pain Relief Post Knee Arthroscopy Using IPACK + Adductor Canal Block Vs. Adductor Canal Block Alone
In this study, the invistigators aim to compare postoperative analgesia effectiveness between combined interspace between the popliteal artery and posterior capsule of the knee block (IPACK) and Adductor canal block vs.
- Trial name
- NCT06265441
- Testing
- Group A will receive adductor canal block after spinal anesthesia under a high-frequency ultrasound guidance in which the adductor canal is identified and 20 ml of 0.25% bupivacaine will be injected, Group B will receive adductor canal block under ultrasound guide 20 ml bupivacaine 0.25% and IPACK block under direct visualization of ultrasound of 20 ml bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Lumbar Disc Herniation, Pain, Postoperative
mTLIP vs. ITP Blocks in Lumbar Disc Surgery
to compare ultrasonography (USG)-guided intertransverse process block and modified thoracolumbar interfascial plan (mTLIP) block in the treatment of postoperative pain in patients undergoing lumbar disc herniation surgery under…
- Conditions
- Lumbar Disc Herniation, Pain, Postoperative, Regional Aneshesia
- Trial name
- NCT06391541
- Testing
- modified thoracolumbar interfacial plan block (mTLIP), Intertransverse process block (ITP)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Post Operative Pain, Opioid Use
Ultrasound-guided Erector Spinae Plane Block Using Catheter for Video-assisted Thoracoscopy
Different modalities ranging from patient controlled analgesia (PCA) to different regional blocks have been used to control postoperative pain after thoracic surgeries.
- Trial name
- NCT05337956
- Testing
- Erector spinae plane block catheter
- Where
- Saudi Arabia
- Volunteers
- 34 people
- Sponsor
- Security Forces Hospital
Endometrial Cancer
a SIngle Center Study of Post-operative STEReotactic RAdiotherapY for Endometrial Cancer
The primary endpoint of the present prospective study is to assess the outcomes in terms of acute toxicity of post-operative stereotactic radiotherapy for endometrial cancer
- Trial name
- SISTER-RAY (NCT06360653)
- Testing
- Stereotactic Post-operative Radiotherapy for Endometrial Cancer
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- ARNAS Civico Di Cristina Benfratelli Hospital
Colorectal Cancer, Wound Infection
Comparing PP and PVDF Meshes in Midline Laparotomy Closure for High-risk Colorectal Surgery. Impact on Incisional Hernia and Surgical Wound Infection.
In the latest guidelines for abdominal wall closure in emergency surgery published in the World Journal of Emergency Surgery (WJES) in 2023, no specific recommendations are made in this regard.
- Conditions
- Colorectal Cancer, Wound Infection, Hernia Incisional
- Trial name
- PROFIMESH (NCT06220045)
- Testing
- Polyvinylidene fluoride mesh, Prophylactic polypropylene mesh
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Postoperative Pain, Ultrasound
Ultrasound Guided Anterior Quadratus Lumborum Block
Percutaneous nephrolithotomy (PNL) is frequently used today for renal stones. percutaneous nephrolithotomy (PNL) procedure has become the treatment of choice for many patients with symptomatic renal stones .
- Trial name
- NCT03425162
- Testing
- Morphine Sulfate, Group P, Group A
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Cesarean Section Pain, Diclofenac
Intramuscular Versus Rectal Diclofenac for Pain Relief After Cesarean Section in Women
The goal of this clinical study is to find out which way of giving diclofenac sodium provides better pain relief after a planned cesarean section: an injection into the muscle or a suppository given through the rectum.
- Conditions
- Cesarean Section Pain, Diclofenac, Suppository, Postoperative Pain
- Trial name
- NCT07379762
- Testing
- Diclofenac 75mg, Diclofenac 50mg
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- CMH Multan Institute of Medical Sciences
Incisional Hernia
RCT Comparing Lightweight vs. Heavyweight Meshes in Incisional Hernia Repair
In this randomized, controlled, prospective multicentre clinical trial with a parallel group design a large-pore, lightweight polypropylene mesh (Ultrapro®) is compared to a small-pore, heavyweight polypropylene mesh…
- Trial name
- NCT04961346
- Testing
- Ultrapro® mesh, Premilene® mesh
- Where
- Germany
- Volunteers
- 188 people
- Sponsor
- RWTH Aachen University
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