Clinical trials: Post-Operative Complications
Asymptomatic Apical Periodontitis
Sonic Irrigation Activation for Postoperative Pain After Root Canal Treatment
This randomized controlled clinical trial will evaluate whether sonic activation of the root canal irrigant using the EndoActivator system reduces postoperative pain after root canal treatment compared with conventional syringe…
- Trial name
- VAS (NCT07847333)
- Testing
- Sonic Irrigation Activation Using EndoActivator, Conventional Syringe Irrigation
- Volunteers
- 176 people
- Sponsor
- Saidu College of Dentistry
Low Anterior Resection Syndrome
The Effect of Melatonin in Patients With Low Anterior Resection Syndrome
The primary objective of the study is to investigate whether treatment with melatonin has an alleviating effect on Low Anterior Resection Syndrome (LARS) symptoms.
- Trial name
- MELLARS (NCT05042700)
- Testing
- Melatonin
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Ismail Gögenur
Post Operative Pain, Apical Periodontitis
Influence of Sonic Activation of Root Sealers on Post-Operative Pain
Aim: This clinical study aims to compare post-operative pain after single-visit root canal treatment of teeth with asymptomatic apical periodontitis using epoxy-resin based AH Plus and calcium silicate based Endosequence BC…
- Trial name
- NCT06403293
- Testing
- Root canal treatment (AH Plus-NA), Root canal treatment (AH Plus-EA), Root canal treatment (BC-NA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Postoperative Pain
Factors Predicting Postoperative Cesarean Section Pain
In spite of identical analgesic protocols, parturients suffer different levels of pain postoperative lay. In this study we hope to identify factors which influence the perception of pain including preoperative anxiety, sleep…
- Trial name
- NCT02033304
- Where
- 2 sites in Israel
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Pain, Postoperative, Premature Infant
Postoperative Pain Control & Relief in Neonates
Pain control for newborns has made significant improvements over the last 30 years. The use of narcotics remains the standard of care for neonates undergoing minor and major surgeries.
- Conditions
- Pain, Postoperative, Premature Infant, Opioid Use
- Trial name
- POPCORN (NCT03677830)
- Testing
- Acetaminophen, Saline
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Post Operative Pain, Acute, Sedation Score
Patient Control Epidural Versus Conventional Epidural.
As one of the complications of THR is post operative pain, which usually requires epidural catheter insertion. We are comparing the effect of patient control epidural versus conventional epidural for patient's satisfaction.
- Conditions
- Post Operative Pain, Acute, Sedation Score, Degree of Motor Block, Length of Hospital Stay
- Trial name
- NCT06721000
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Hand Hygiene, Surgical Wound Infection
Surgical Handwashing: Drying With One or Two Surgical Towels
This study aims to determine whether the use of two sterile towels for drying after surgical handwashing results in fewer contamination events compared to the use of only one towel among healthcare personnel.
- Conditions
- Hand Hygiene, Surgical Wound Infection, Healthcare Associated Infection, Medical Errors
- Trial name
- NCT06420934
- Testing
- Drying procedure after surgical handwashing
- Where
- Colombia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Instituto de Ortopedia Infantil Roosevelt
Blood Loss, Surgical, Blood Loss, Postoperative
Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine Atony
This research study is being done to learn what effect a single dose of calcium gluconate will have on blood loss at the time of cesarean delivery in pregnancy patients at high risk for uterine atony.
- Conditions
- Blood Loss, Surgical, Blood Loss, Postoperative, Uterine Atony
- Trial name
- NCT07217899
- Testing
- Calcium Gluconate, Saline
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Michigan
Post Operative Pain, Chronic Pain
Performance and Safety of the ANTALGEEK® Thess Monitoring Medical Device in the Outpatient Management of Acute Pain and Postoperative Recovery
Acute postoperative pain (APOP) is a major public health problem, affecting nearly 10 million patients in France each year. Effective analgesic therapy in the first postoperative week is a key factor in reducing early…
- Trial name
- TRACE (NCT07680998)
- Testing
- Post-operative follow-up using the Thess Telemonitoring device in conjunction with the ANTALGEEK® protocol
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hypospadias
Caudal vs Local Anesthesia in Hypospadias
Hypospadias is one of the most common congenital malformations of the genitalia in boys, and is typically managed by surgical intervention.
- Trial name
- CLASH (NCT02512887)
- Testing
- Caudal Block Anesthesia, Dorsal Penile Block Anesthesia
- Where
- 4 sites in Canada
- Volunteers
- 224 people
- Sponsor
- McMaster University
Phantom Limb Pain
Incidence of Phantom Limb Pain and Method of Anesthesia After Lower Extremity Amputation
Phantom limb pain (pain originating from where an amputated limb once was) is a common occurrence after lower extremity amputations, with some sources noting incidence to be as high as 60-80% six months after surgery.
- Trial name
- NCT01003704
- Testing
- Lower extremity amputation
- Where
- United States
- Sponsor
- North Texas Veterans Healthcare System
Pain, Postoperative
Prediction of Pain in Total Knee Arthroplasty
In this consecutive, prospective cohort study trial the investigators evaluate if preoperative pain response upon heat stimulation is predictive for acute and subacute postoperative pain after total knee arthroplasty.
- Trial name
- NCT01179204
- Testing
- Preoperative heat stimulation
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Hvidovre University Hospital
Abscess, Wound Infection
Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections
The primary object is to compare the early clinical efficacy (after 48-72 hours of therapy) of dalbavancin to the comparator regimen (vancomycin with the option to switch to oral linezolid) for the treatment of patients with a…
- Conditions
- Abscess, Wound Infection, Surgical Site Infection, Cellulitis
- Trial name
- NCT01431339
- Testing
- IV Dalbavancin, Vancomycin/Linezolid
- Where
- 137 sites in United States, Bulgaria and 12 more
- Volunteers
- 739 people
- Sponsor
- Durata Therapeutics Inc., an affiliate of Allergan plc
Incisional Hernia
Incisional heRnia dIgestion Sexuality
After an operation on the abdomen, some patients present with an incisional hernia(incisional hernia) which causes a permanent exteriorization of the vicera. This situation is at the origin of postural problems.
- Trial name
- IRIS (NCT05596357)
- Testing
- questionnaires
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Anesthesia, Postoperative Complications
D-FAB-POUR Trial: Dexmedetomidine vs Fentanyl as Adjuvants to Bupivacaine on Postoperative Urinary Retention
This study aims to compare two medications, dexmedetomidine and fentanyl, when used alongside a commonly used spinal anesthetic called bupivacaine in patients undergoing lower limb surgery.
- Conditions
- Spinal Anesthesia, Postoperative Complications, Dexmedetomidine, Fentanyl
- Trial name
- D-FAB-POUR (NCT07117565)
- Testing
- Intervention 1: Intrathecal Dexmedetomidine with Bupivacaine, Intervention 2: Intrathecal Fentanyl with Bupivacaine
- Where
- Nepal
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Circadian Rhythm, Postoperative Pain
The Effect of Circadian Rhytm on Postoperative Pain Undergoing Pediatric Surgery
These circadian rhythms are self-sustained, endogenous oscillations generated by circadian clocks that persist with a period of around 24 -h under constant conditions.
- Trial name
- NCT05379192
- Testing
- Group 1, Group 2, Group 3, Group 4
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Faruk Cicekci
Varicocele
Assessing the Rates of Major Complications in Combined Mini-incision Microscopic Varicocelectomy
The purpose of this study is to determine the rates of major post-varicocelectomy complications (Recurrence, Hydrocele and Testicular Atrophy) in patients operated with a new method named Combined Mini-incision Microscopic…
- Trial name
- CMMV (NCT02092311)
- Testing
- Combined Microscopic Varicocelectomy, Inguinal and Subinguinal varicocelectomy
- Where
- Iran
- Volunteers
- 570 people
- Sponsor
- Omid Fertility Center
Short Bowel Syndrome
Safety and Immunogenicity of Rotavirus Vaccine (RotaTeq(R)) in Infants With Short Bowel Syndrome
Rotavirus infection is a common pediatric illness and is the leading cause of severe acute gastroenteritis (vomiting and diarrhea) in infants and young children.
- Trial name
- NCT00767364
- Testing
- Oral, live, pentavalent rotavirus vaccine; RotaTeq(R)
- Where
- 3 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Michigan
Pain, Postoperative
Benefit of Acupuncture Combined to Regional Analgesia for Post Operative Pain Relief After Hysterectomy
Since the 90's, the quality of the post operative pain relief is a main concern in most of the healthcare systems in the world. An efficient pain relief improves the quality of recovery after surgery [Level 1A], reduces the risk…
- Trial name
- RAACU (NCT06002464)
- Testing
- Acupuncture, Bilateral ESP catheter
- Where
- Vietnam
- Volunteers
- 72 people
- Sponsor
- Vinmec Healthcare System
Pain, Postoperative, Ropivacaine
Effect of Nervus Cutaneous Femoris Lateralis-Blockade on Moderate Pain Responders After Total Hip Arthroplasty
The patients will be included the 1. or 2. day after surgery. All THA patients will be screened. Those reporting VAS > 40 during active 30 degrees hip flexion will be asked to participate.
- Conditions
- Pain, Postoperative, Ropivacaine, Therapeutic Use, Arthroplasty, Replacement, Hip
- Trial name
- NCT02344264
- Testing
- Ropivacaine, Saline
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Daniel Hägi-Pedersen
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