Clinical trials: Post-Operative Complications
Osteo Arthritis Knee, Pain, Postoperative
Comparing Single Dose and Multiple Dose of Dexamethasone Post TKA
The goal of this clinical trial is to investigate the efficacy of single dose and double dose of dexamethasone after primary total knee replacement.
- Trial name
- NCT06339151
- Testing
- Dexamethasone before surgery, Dexamethasone before and 12 hours after surgery, Dexamethasone before and 24 hours after surgery
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Thammasat University Hospital
Peripheral Nerve Block Procedure
Prospective Post-market Evaluation of an Echogenic Catheter
Patients scheduled for mastectomy and suitable for paravertebral block will be randomized to one of 2 groups. Group 1 will have the nerve block performed using a standard non-echogenic needle and catheter under ultrasound…
- Trial name
- EchoCath (NCT02136446)
- Testing
- EchoGlo Nerve Block Catheter, Pajunk® Nerve Block Catheter
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Smiths Medical, ASD, Inc.
Postoperative Pulmonary Complications
Effect of Ascorbic Acid on Postoperative Pulmonary Complications in Patients Undergoing Cardiac Surgery
Postoperative pulmonary complications(PPCs) including, but not limited to ,hypoxemia, pneumonia, ventilator-induced lung injury, and acute respiratory distress syndrome (ARDS),atelectasis,pleural effusion .PPCs may result in…
- Trial name
- NCT03756727
- Testing
- Ascorbic Acid, Saline
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Xuzhou Medical University
Emergency Colorectal Surgery in Ultra 80 Patients
Colorectal Emergencies in Elderly Patients.
Colon diseases can turn in a clinical emergency with the onset of some important complications. Some critical conditions are more common in aged patients because they are more frails.
- Trial name
- NCT05443386
- Testing
- colorectal surgery
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- University of Foggia
Staphylococcal Skin Infections, Diabetic Foot Infections
A Complicated Skin and Soft-tissue Infection Patient Registry
The purpose of this registry is to better understand (1) complicated skin and soft-tissue infections requiring hospitalization, and (2) clinical and economic outcomes in hospitalized patients receiving intravenous antibiotic…
- Conditions
- Staphylococcal Skin Infections, Diabetic Foot Infections, Surgical Wound Infection, Abscess
- Trial name
- NCT00737269
- Volunteers
- 1,081 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Pancreatic Diseases
The Effect of Preoperative Long Period Octreotide Combined With Postoperative Short Period Octreotide on the Complications After Pancreatectomy. A Prospective, Multicenter Clinical Trial
The Effect of Preoperative Long Period Octreotide Combined With Postoperative Short Period Octreotide on the Complications After Pancreatectomy. A Prospective, Multicenter Clinical Trial
- Trial name
- NCT03398941
- Testing
- Preoperative Long Period Octreotide Combined With Postoperative Short Period Octreotide
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chengfeng Wang
Cervical Cancer, Endometrial Cancer
Postoperative Hypofractionated Radiation in Cervical and Endometrial Tumours: Phase II Study
The primary aim of the trial is to investigate the late effects of hypofractionated external radiation (39 Gy in 13 fractions) in patients requiring post-operative radiation for early-stage cervical and endometrial cancers.
- Trial name
- PARCERII (NCT05857631)
- Testing
- Hypofractionated Image guided External Beam Radiation Therapy (EBRT), Cisplatin, Vaginal brachytherapy
- Where
- 2 sites in India
- Volunteers
- 90 people
- Sponsor
- Tata Memorial Centre
Pain, Postoperative, Surgery, Oral
Licorice Versus Sugar-water Gargling for Pain in Patients Recovering From Ear-Nose-Throat and Maxilla-Facial Surgery
Our primary aim is to determine whether licorice gargling provides meaningful analgesia after oral surgery. Specifically, we propose to test the primary hypothesis that gargling with licorice solution reduces pain after oral…
- Trial name
- NCT02968823
- Testing
- Licorice, Sugar water
- Where
- Austria
- Volunteers
- 127 people
- Sponsor
- Medical University of Vienna
Postoperative Complications
Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?
the investigators aim is to investigate and explore the effect 10 mg morphine added to local anesthetics in serratus anterior plane block for post mastectomy pain management after modified radical mastectomy in patients with…
- Trial name
- NCT02962024
- Testing
- Morphine Sulfate, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fatma Adel El sherif,MD
Postoperative Pain
Rhomboid Intercostal Block Versus Serratus Anterior Plane Block
evaluate and compare the impact of ultrasound guided rhomboid intercostal block versus serratus anterior plane block for analgesia after thoracodorsal artery perforator flap following partial mastectomy
- Trial name
- NCT05661279
- Testing
- general anesthesia, general anesthesia plus Rhomboid intercostal block, Serratus anterior plane block
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Post Operative Pain
Caudal Block vs Retrolaminar Block on Analgesic Consumption in Undescended Testis Surgeries
This study compares the postoperative analgesic effectiveness of Caudal Block (CB) and Retrolaminar Block (RLB) in pediatric patients undergoing undescended testis surgeries.
- Trial name
- NCT06725862
- Testing
- Retrolaminar Block (RLB), Caudal Block (CB)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Surgical Site Infections
PHMB-based Antiseptic Use in Full-thickness Surgical Wounds
To study the effect of applying a PHMB-based antiseptic solution to tie-over dressings in full-thickness surgical wounds in dermatologic surgery in order to minimise the development of surgical site infections.
- Trial name
- NCT02253069
- Testing
- Applying Prontosan antiseptic solution to tie-over dressings
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Region Skane
Acute Postoperative Pain
Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of HYR-PB21 in Healthy Volunteers
This study is the first time into human study (FTIH) for HYR-PB21 for injection. The study will evaluate the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending and single subcutaneous dose of HYR-PB21 for…
- Trial name
- NCT04169256
- Testing
- HYR-PB21, Liposomal bupivacaine, Normal Saline
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fruithy Medical Pty Ltd
Bladder Tumors, Spinal Anesthesia
Magnesium vs. Dexmedetomidine in TURBT Under Spinal Anesthesia
This randomized controlled trial evaluated the effects of intraoperative intravenous magnesium sulfate versus dexmedetomidine on postoperative pain, analgesic consumption, hemodynamic stability, and respiratory function in…
- Conditions
- Bladder Tumors, Spinal Anesthesia, Postoperative Pain, Magnesium Sulfate
- Trial name
- TURBT (NCT07445451)
- Testing
- magnesium sulfate, Dexmedetomidine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Obesity, Postoperative Bariatric Surgery
Lung Ultrasound Evaluation of the Effects of PEEP and Recruitment Strategies Adjusted for Intraoperative Dynamic Compliance on Postoperative Respiratory Complications in Obese Patients Planned for Laparoscopic Surgery
This study aims to investigate the effects of the personalized application of respiratory pressures applied to patients undergoing laparoscopic bariatric surgery when they are connected to a ventilator under general anesthesia…
- Conditions
- Obesity, Postoperative Bariatric Surgery, Laparoscopic Surgery, Individualized PEEP Treatment Strategy
- Trial name
- NCT06994780
- Testing
- dynamic compliance guided PEEP titration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Mild Cognitive Impairment
The Effect of Nimodipine on the Postoperative Cognitive Dysfunction
The calcium channel blocker nimodipine dilates cerebral blood vessels and can pass through the blood-brain barrier, providing neuroprotective effects by selectively improving cerebral blood flow and inhibiting neuronal necrosis…
- Trial name
- NCT02537080
- Testing
- Nimodipine group, Control group
- Where
- Czechia
- Volunteers
- 15 people
- Sponsor
- University Hospital Hradec Kralove
Pain, Pain Syndrome
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06071988
- Testing
- Adezunap (AP707)
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Laparoscopic Cholecystectomy, Optic Nerve Sheath Diameter Measurement
Effects of Bolus Versus Infusion Ketamine During Laparoscopic Cholecystectomy
This prospective, randomized, controlled study evaluated the effects of different ketamine administration strategies in adult patients undergoing elective laparoscopic cholecystectomy under general anesthesia.
- Conditions
- Laparoscopic Cholecystectomy, Optic Nerve Sheath Diameter Measurement, Ketamine, Postoperative Pain
- Trial name
- ketamine (NCT07900854)
- Testing
- ketamine bolus, ketamin infusion, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Albumin; Double
Determination of Albumina as an Early Predictor of Postoperative Infections in Colorectal Surgery
Colorectal surgery has traditionally been associated with significant morbidity and prolonged hospital stay. Overall complication rates have been reported to be 26-35%.
- Trial name
- ALB-CIR (NCT03643523)
- Testing
- Albumine detection
- Volunteers
- 70 people
- Sponsor
- Corporacion Parc Tauli
Rotator Cuff Tear, Postoperative Pain
Interscalene Block With and Without Liposomal Bupivacaine in Shoulder Surgery
The purpose of this study is to examine the difference in perioperative pain after shoulder surgery with a standard bupivacaine nerve block compared to liposomal bupivacaine enhanced nerve block alone in TSA and ARCR.
- Trial name
- NCT03728946
- Testing
- Liposomal Bupivacaine
- Where
- 6 sites in United States
- Volunteers
- 100 people
- Sponsor
- Orthopaedic & Neurosurgery Specialists
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