Clinical trials: Post-Operative Complications
Analgesia, Hip Arthropathy
Pericapsular Nerve Block Versus Intrathecal Morphine for Analgesia After Primary Hip Arthroplasty
The aim of this clinical trial is to compare the analgesic effect of pericapsular nerve block (PENG) with intrathecal morphine in patients scheduled for total hip replacement surgery.
- Conditions
- Analgesia, Hip Arthropathy, Post Operative Pain
- Trial name
- PENGIT (NCT06317870)
- Testing
- Intrathecal morphine, Pericapsular nerve group block (PENG)
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Surgical Site Infection
Efficacy Study of Delayed Primary Closure to Reduce Rate of Wound Infection in Complicated Appendicitis
Research hypothesis: Does delayed primary wound closure after appendectomy in adults with complicated appendicitis reduce postoperative superficial surgical site infection compare to primary wound closure.
- Trial name
- NCT01659983
- Testing
- Primary wound closure
- Where
- 7 sites in Thailand
- Volunteers
- 600 people
- Sponsor
- Ramathibodi Hospital
Surgical Wound Dehiscence, Wound Infection
Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy
Wound complications after Cesarean section (C-section) are common in obese women. Approximately 25% of obese women having a C-section will have a wound complication.
- Trial name
- NCT00654641
- Testing
- Negative pressure wound closure, Standard wound closure
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- West Virginia University
Atrial Fibrillation, Surgery--Complications
Incidence of Post-operative Atrial Fibrillation Secondary to Abdominal Surgery
Background and purpose Post-operative AF (POAF) is considered a phenomenon rather than a definite diagnosis and the current clinical guidelines have no specific recommendations regarding its management.
- Trial name
- SECAFIB-SURG (NCT04090905)
- Testing
- Standard clinical monitoring, Holter monitoring
- Where
- Denmark
- Volunteers
- 466 people
- Sponsor
- Frederiksberg University Hospital
Cardiac Surgery, Coronary Artery Bypass Grafting
Oscillating Positive Expiratory Pressure (OPEP) Therapy in High Risk Patients Following Cardiac Surgery
Respiratory dysfunction following cardiac surgery is well documented and due in part to the location of the incision and nature of the surgery.
- Conditions
- Cardiac Surgery, Coronary Artery Bypass Grafting, Chronic Obstructive Pulmonary Disease (COPD), Older Adults
- Trial name
- NCT02732574
- Testing
- Oscilatory Positive Expiratory Pressure (OPEP) device
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hernia, Umbilical, Clonidine
Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty
This clinical trial aims to evaluate the effectiveness of an ultrasound-guided nerve block technique as the sole anesthetic method for patients undergoing outpatient umbilical hernia surgery.
- Conditions
- Hernia, Umbilical, Clonidine, Pain, Postoperative, Ambulatory Surgical Procedures
- Trial name
- NCT07062497
- Testing
- Rectus Sheath Block, Rectus Sheath Block with Clonidine
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Head and Neck Neoplasms, Drain Site Complication
Ideal Drainage Output of Post-operative Neck Suction Drain
A precautionary measure that is frequently used after a neck surgery is the usage of suction drains, which allow the evacuation or air and fluids accumulated at the site of the surgery using negative pressure.
- Conditions
- Head and Neck Neoplasms, Drain Site Complication, Neck Dissection
- Trial name
- NCT03971760
- Testing
- Suction drain removal
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Endotracheal Intubation, Robotic Esophagectomy
The Association of Intraoperative Oxygen Reserve Index and Postoperative Pulmonary Complications in Robot-assisted Esophagectomy
The World Health Organization (WHO) has proposed the use of 80% high-dose inhalation oxygen (FiO2) during surgery to reduce postoperative infection in adult patients undergoing general anesthesia.
- Conditions
- Endotracheal Intubation, Robotic Esophagectomy, Esophagectomy
- Trial name
- NCT04008420
- Testing
- monitoring of the oxygen reserve index
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Surgical Complications
Impact of Pasireotide on Postoperative Pancreatic Fistulas Following Distal Resections
Between 2000 and 2016 258 distal pancreatectomies were performed at our University Hospital which were included in our analysis. Pasireotide was used in between July 2014 and April 2016.
- Trial name
- NCT04281680
- Testing
- Pasireotide 0.9 MG/ML
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Postoperative Ileus, Anastomotic Leak
SANICS II Trial: Stimulation of the Autonomic Nervous System in Colorectal Surgery by Perioperative Nutrition
The main objective is to investigate the effects of perioperative nutrition on postoperative ileus and anastomotic leakage in patients undergoing colorectal surgery.
- Trial name
- SANICSII (NCT02175979)
- Testing
- enriched enteral nutrition, standard
- Where
- 5 sites in Denmark, Netherlands
- Volunteers
- 280 people
- Sponsor
- Misha D.P. Luyer
Postoperative Pain
Erector Spinae Block With Ropivacaine and Dexmedetomidine on Opioid Consumption After Lumar Spine Surgeries
The aim of this study is to investigate the role of 0.5 micrograms/kg of dexmedetomidine with 0.2 % ropivacaine in erector spinae block in reducing opioid consumption for patients undergoing lumbar spine surgeries.
- Trial name
- NCT05664542
- Testing
- ESPB (regional Block), ropivacaine and dexmedetomidine
- Where
- Saudi Arabia
- Volunteers
- 42 people
- Sponsor
- Security Forces Hospital
Paresthesia, Total Hip Arthroplasty (THA)
Percussive vs. Gentle Massage for Recovery After Hip Replacement
Many people who have hip replacement surgery through a "bikini incision" on the front of the hip (anterior approach) develop numbness, tingling, burning, or tightness in the front and side of the thigh afterward.
- Conditions
- Paresthesia, Total Hip Arthroplasty (THA), Direct Anterior Total Hip Arthroplasty, Lateral Femoral Cutaneous Nerve Injury
- Trial name
- NCT07790705
- Testing
- Percussive Massage Therapy (Toloco or Hyperice Hypervolt GO 2), Gentle Manual Massage
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Zachary M Ricciardelli
Cardiac Arrest
Vitamin C in Post-cardiac Arrest
Only half of the patients suffering from cardiac arrest arrive at the hospital alive. Of these survivors, more than 50% will still die or remain severely disabled.
- Trial name
- VITaCCA (NCT03509662)
- Testing
- Vitamin C, Thiamine
- Where
- Netherlands
- Volunteers
- 270 people
- Sponsor
- Amsterdam UMC, location VUmc
Short Bowel Syndrome, Intestinal Failure
Level of Deprivation Assessment in a Population of Short-bowel Syndrome Patients With Intestinal Failure
The association between social deprivation and chronic disease is regularly examined but there are no data available on patients with intestinal failure due to short bowel syndrome (SBS-IF).
- Conditions
- Short Bowel Syndrome, Intestinal Failure, Deprivation, Psychosocial
- Trial name
- PRECAR-SGC (NCT06391762)
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Central Hospital, Nancy, France
Overall Survival, Postoperative Complications
Clinical Value of Left Colic Artery in Laparoscopic Radical Rectectomy
Colorectal cancer is one of the most common tumors in Asia. According to the recent research, surgical procedure could provide more treatment benefit in rectal cancer.
- Trial name
- NCT03349788
- Testing
- LCA-nP, LCA-P
- Where
- China
- Volunteers
- 354 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Perioperative Myocardial Injury, Myocardial Injury After Non-Cardiac Surgery
Intrahepatic Blood Flow Occlusion and Cardiac Injury Risk in Partial Hepatectomy
The goal of this observational study is to examine whether intrahepatic blood flow occlusion strategies during partial hepatectomy are associated with postoperative cardiac injury in patients undergoing hepatectomy.
- Conditions
- Perioperative Myocardial Injury, Myocardial Injury After Non-Cardiac Surgery, Hypotension, Ischemia Reperfusion Injury
- Trial name
- NCT06753461
- Testing
- intrahepatic blood flow occlusion
- Volunteers
- 2,600 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Gastric Adenocarcinoma, Laparoscopic Gastrectomy
Feasibility of Enhanced Recovery After Surgery Without Prophylactic Abdominal Drainage Tubes After Laparoscopic Distal Gastrectomy For Gastric Cancer
This study aims to compare the effects of using prophylactic abdominal drainage tubes during Enhanced Recovery After Surgery (ERAS) in patients undergoing Laparoscopic Distal Gastrectomy (LDG) for gastric cancer through a…
- Conditions
- Gastric Adenocarcinoma, Laparoscopic Gastrectomy, Complications
- Trial name
- NCT07029269
- Testing
- ERAS-tubeless group, ERAS-tube group
- Where
- 6 sites in China
- Volunteers
- 454 people
- Sponsor
- Zuoyi Jiao
Inguinal Hernia, Postoperative Pain
TENS for Pain and Sleep After Hernia Surgery
This study evaluates whether Transcutaneous Electrical Nerve Stimulation (TENS) improves postoperative pain and sleep quality in adults undergoing inguinal hernia surgery.
- Conditions
- Inguinal Hernia, Postoperative Pain, Sleep Disturbance
- Trial name
- TENS-HERNIA (NCT07319754)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Standard Postoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nigde Omer Halisdemir University
Lung Cancer
Postoperative Pain After Single Port, Two Ports and Three Ports VATS Lobectomy
This single-center, prospective, randomized controlled trial was designed to assess and compare the postoperative pain after VATS lobectomy performed though one, two and three incisions.
- Trial name
- NCT03228056
- Testing
- pain intensity measured in VAS scale
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Pulmonary Hospital Zakopane
General Anesthesia
The Relationship Between the SPI and the Postop ED
Surgical plethysmography index (SPI) is a device that can noninvasively monitor the balance between the nociception and ant-nociception using pulse photoplethysmographic amplitude (PPGA) and heart rate obtained through an oxygen…
- Trial name
- SPI_ED (NCT03328910)
- Testing
- SPI monitor (GE Healthcare, Helsinki, Finland)
- Where
- South Korea
- Sponsor
- Daegu Catholic University Medical Center
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