Clinical trials: Post-Operative Complications
Injury of Foot, Shoulder or Knee, Perineural Analgesia
Postoperative Patient-controlled Perineural Analgesia After Orthopedic Surgery by "Remote Control" Versus "Bedside Care"
Perineural injection of local anesthesic is currently the reference method for the treatment of post operative pain in a patient undergoing major orthopedic surgery. Postoperative pain is a dynamic phenomena in every patient.
- Conditions
- Injury of Foot, Shoulder or Knee, Perineural Analgesia, Pain, Postoperative
- Trial name
- MICREL (NCT02018068)
- Testing
- Remote control, At bedside care
- Where
- 4 sites in France, Netherlands and 1 more
- Volunteers
- 72 people
- Sponsor
- University Hospital, Montpellier
Postoperative Pain, Hysterectomy
Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery
This study will be investigating the efficacy and safety administration of multiple doses of intravenous (IV) acetaminophen (IVAPAP) in the 48 hour period following Gynecologic Surgery.
- Trial name
- NCT00399568
- Testing
- IV Acetaminophen
- Where
- 27 sites in United States
- Volunteers
- 331 people
- Sponsor
- Mallinckrodt
Emergence Agitation
Propofol Versus Dexmedetomidine Effect on Prevention Emergence Agitation
The goal of this clinical trial is to compare Propofol versus Dexmedetomidine in children undergoing squint surgery. The main question it aims to answer is: Which drug is more effective in preventing the appearance of Emergence…
- Trial name
- NCT06312618
- Testing
- Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Acute Myocardial Infarction (AMI)
Stellate Ganglion Morphine Infiltration on Myocardial I/R Injury
The goal of this clinical trial is to investigate whether morphine modulates the functions of the stellate ganglion to reduce myocardial ischemia/reperfusion (I/R) injury in AMI patients.
- Trial name
- tSGM-AMI (NCT07023679)
- Testing
- Morphine
- Where
- 2 sites in China
- Volunteers
- 2,588 people
- Sponsor
- The Second Hospital of Anhui Medical University
Rectal Cancer
Selective sPlenic flExure Mobilization for Low colorEctal Anastomosis After D3 lYmph Node Dissection (Speedy Trial)
In the Low Anterior Resection of rectum for cancer, the section level of IMA and the need of SFM is still debated. The aim of this study is to explore the different impacts of high and low ligation with peeling off vascular…
- Trial name
- SpeeDy (NCT03895255)
- Testing
- Paraaortic lymph node dissection, IMA high ligation, TME, routine splenic flexure mobilization, Paraaortic lymph node dissection, IMA low ligation, TME, selective splenic flexure mobilization
- Where
- Russia
- Volunteers
- 142 people
- Sponsor
- Russian Society of Colorectal Surgeons
Postoperative Delirium, PD
Perioperative Cognitive Function - Dexmedetomidine and Cognitive Reserve
Elderly patients who undergo anesthesia and non-cardiac surgery are subject to deterioration of brain function including the development of postoperative delirium (PD) and postoperative cognitive dysfunction (POCD).
- Conditions
- Postoperative Delirium, PD, Postoperative Cognitive Dysfunction, POCD
- Trial name
- NCT00561678
- Testing
- Precedex (Dexmedetomidine)
- Where
- 10 sites in United States
- Volunteers
- 404 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Amputation, Surgical, Amputation, Traumatic
Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation
When a limb is severed, pain perceived in the part of the body that no longer exists often develops and is called "phantom limb" pain.
- Conditions
- Amputation, Surgical, Amputation, Traumatic, Phantom Limb Pain, Phantom Pain Following Amputation of Lower Limb
- Trial name
- NCT06071715
- Testing
- ACTIVE cryoneurolysis
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Diego
Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum
Human Intestinal Microbiome and Surgical Outcomes in Patients Undergoing Colorectal Cancer Surgery
Intro: Recent studies on colorectal cancer surgery have been focusing on the role of intestinal microbiome on surgical outcomes.
- Trial name
- Microbiota (NCT04005118)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Surgery, Stoma Ileostomy
Trans Abdominal Plane Block (TAP Block) in Surgery of Stoma Reversal and Its Effect on Post Operative Recovery: a Prospective, Randomized, Muticenter Study
The primary purpose of TAPAS study is to demonstrate the superiority of analgesic effect of trans abdominal plane block (TAP block) performed at the beginning of stoma reversal, compared to standard of care.
- Trial name
- Tapas (NCT03971513)
- Testing
- Trans abdominal plane
- Where
- 2 sites in France
- Volunteers
- 149 people
- Sponsor
- University Hospital, Clermont-Ferrand
Postoperative Pain
Comparison of the Quadratus Lumborum Block With the Transversus Abdominis Plan Block
In this study, investigators aimed to compare the Quadratus Lumborum Block and the Transversus Abdominis Plan Block for postoperative pain control after laparoscopic cholecystectomy
- Trial name
- NCT03112915
- Testing
- quadratus lumborum block, Transversus abdominis plan block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kecioren Education and Training Hospital
Respiratory Failure, Respiratory Infection
Avoiding Neuromuscular Blockers to Reduce Complications
The goal of this study to evaluate whether eliminating the use of non-depolarizing neuromuscular blocking agents (NMBA) for maintenance of general anesthesia reduces postoperative pulmonary complications in higher risk patients.
- Conditions
- Respiratory Failure, Respiratory Infection, Aspiration Pneumonia, Pneumonitis
- Trial name
- NCT03962725
- Testing
- Neuromuscular Blocking Agents, Anesthetic Adjuncts
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Beth Israel Deaconess Medical Center
Gingival Bleeding, Prosthesis Failure, Dental
Comparison of Effectiveness of Gingival Displacement Using Retraction Cord and Aluminum Chloride Gel
This study aims to compare the horizontal gingival displacement by using a retraction cord and aluminum chloride gel, and also to determine the time taken for placement and hemorrhage after the procedure by using a retraction…
- Conditions
- Gingival Bleeding, Prosthesis Failure, Dental, Tissue Injury
- Trial name
- NCT07255976
- Testing
- knitted cotton retraction cord, aluminum chloride gel
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Anemia, Surgery
Anemia and Red Blood Cells Transfusion in Oncological Surgery
Oncologic patients experience anemia and anemia is associated with poor prognosis. Transfusion is associated with adverse events, and equipoise remains on the optimal transfusion strategy in oncologic patients in surgical…
- Conditions
- Anemia, Surgery, Oncology
- Trial name
- IMPACT (NCT04101240)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Delirium, Awakening, Post-Anesthesia Delayed
Validation and Reliability of the Turkish 4AT Scale for Post-Anesthesia Awakening Delirium
Background: Delirium is a common and serious condition in hospitalized patients that often leads to extended hospital stays and increased healthcare costs. Accurate and timely detection is essential for optimal patient outcome.
- Conditions
- Delirium, Awakening, Post-Anesthesia Delayed, Delirium, Postoperative, Nurse's Role
- Trial name
- NCT06187389
- Testing
- 1 Grups
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Postoperative Wound Infection
Efficacy Study of Antiseptic Preoperative Scrubs in Prevention of Postoperative Infections
Most cases of infection of clean-contaminated wounds (wounds without gross spillage of organisms from the gastrointestinal tract) are thought to originate from the skin.
- Trial name
- NCT00290290
- Testing
- chlorhexidine-alcohol, Povidone-Iodine
- Where
- 6 sites in United States
- Volunteers
- 849 people
- Sponsor
- Baylor College of Medicine
Breast Neoplasms, Breast Reconstruction
DIEP-MDS for Risk Stratification of Flap Vascular Compromise and Failure in Breast Reconstruction
This multicenter retrospective observational study will develop and validate a CTA-based quantitative risk score-the DIEP Morphological Deviation Score (DIEP-MDS)-to estimate the risk of flap-related vascular compromise and flap…
- Conditions
- Breast Neoplasms, Breast Reconstruction, Postoperative Complications
- Trial name
- DIEP-MDS (NCT07761390)
- Where
- 20 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Zhuliling
Brain Ischemia, Postoperative Confusion
Impact of Remote Ischemic Preconditioning Preceding Coronary Artery Bypass Grafting on Inducing nEuroprotection
Coronary artery disease (CAD) is the leading cause of death worldwide. Patients with severe CAD are often treated with coronary artery bypass grafting (CABG).
- Trial name
- RIPCAGE (NCT02177981)
- Testing
- Remote ischemic preconditioning, Control
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- University of Zagreb
Acute Appendicitis, Perforated Gastroduodenal Ulcer
Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures
Aim of prospective randomized a placebo controlled study is to prove that in case of acute surgical procedure due to appendicitis, ileus of small bowel and perforation of small bowel and stomach appropriately administered…
- Conditions
- Acute Appendicitis, Perforated Gastroduodenal Ulcer, Small Bowel Obstruction
- Trial name
- NCT01524081
- Testing
- Metronidazole, Cefuroxime, Amoxicillin (+ clavulanic acid) and Fluconazole
- Where
- Czechia
- Volunteers
- 187 people
- Sponsor
- The Faculty Hospital Na Bulovce
Postoperative Analgesia, Hand Strength
Long-term Outcomes of Breast Cancer Patients After Wound Infiltration Analgesia
In the study that was conducted from 05.01.2009 - 31.12.2012. 120 patients were examined. By drawing random numbers, the patients were randomized into 3 groups for postoperative analgesia: 1. Diclofenac 2 mg/kg/day - control, 2.
- Conditions
- Postoperative Analgesia, Hand Strength, Health Related Quality of Life, Chronic Shoulder Pain
- Trial name
- NCT05829707
- Testing
- Diclofenac Sodium, Levobupivacaine bolus analgesia, Levobupivacaine PCA group
- Volunteers
- 120 people
- Sponsor
- Osijek University Hospital
Pain, Postoperative
Pain Evaluation of Venous Cannulation to Predict Postoperative Pain
The investigators have recently reported a relationship between pain induced by peripheral venous cannulation and postoperative pain.
- Trial name
- NCT02982109
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Lund University
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