Clinical trials: Post-Operative Delirium
Postoperative Delirium, Preoperative Anxiety
Music Intervention to Reduce Anxiety and Prevent Delirium in Older Adults Undergoing Cardiac Surgery
The goal of this clinical trial is to evaluate the effectiveness of the music intervention in preventing postoperative delirium (POD) in older patients undergoing elective cardiac surgery.
- Conditions
- Postoperative Delirium, Preoperative Anxiety, Cardiac Surgery
- Trial name
- MELODY (NCT07851194)
- Testing
- Music Intervention Group
- Where
- Belgium
- Volunteers
- 256 people
- Sponsor
- KU Leuven
Delirium, Anesthesia; Adverse Effect
Assessment of Immediate Postoperative Delirium (IPD) in Adult Patients: Incidence and Etiologic Factors
Delirium is considered to be acute failure of central nervous system. It is acute confusional state characterized by decline from baseline mental level, attention deficit and disorganized thinking.
- Trial name
- AIPDAP (NCT03967496)
- Testing
- Types of Anesthesia, Access of Surgery, Comorbidities
- Where
- Oman
- Volunteers
- 402 people
- Sponsor
- Sultan Qaboos University
Post-operative Delirium
A Placebo Controlled Trial Of L-Tryptophan In Post-Operative Delirium
Post-operative delirium is a common and deleterious complication in elderly patients. The investigators have previously found lower levels of serum tryptophan in post-operative elderly patients who developed delirium in…
- Trial name
- NCT00865202
- Testing
- L-tryptophan supplementation
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- University of Colorado, Denver
Emergence Agitation, Pain
Can Acetaminophen Given 1-2 Hours to Children Before Ear Tube Surgery Reduce Agitation After Anesthesia?
Emergence agitation (EA) occurs in up to 67% of pediatric patients after anesthesia for bilateral myringotomy tubes (BMT, "ear tubes").
- Trial name
- NCT01737593
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Dexmedetomidine, Delirium
Effect of Dexmedetomidine on Postoperative Delirium After Awake Craniotomies
Postoperative delirium (POD) is a common complication, and the incidence of POD ranges from 10% to 60%. Previous studies suggested that frontal approach and tumor located at the temporal lobe were independent risk factors for POD…
- Conditions
- Dexmedetomidine, Delirium, Awake Craniotomy
- Trial name
- NCT05195034
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Beijing Tiantan Hospital
Insomnia, Postoperative Delirium
Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients
The Sleep Optimization for Brain Health Outcomes in Older Surgical Patients (SLEEP-BOOST) is a pilot randomized, controlled, singled-blinded (participant) trial in major orthopedic joint surgery patients that will build on a…
- Conditions
- Insomnia, Postoperative Delirium, Delayed Neurocognitive Recovery, Postoperative Neurocognitive Disorder
- Trial name
- SLEEP-BOOST (NCT06375265)
- Testing
- digital Cognitive Behavioral Therapy for Insomnia (dCBT-I), Sleep Health Education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Anesthesia, Hip Osteoarthritis
The Assessments of the Postoperative Recovery on Elderly Patients Received General Anesthesia or Peripheral Nerve Blocks
Postoperative recovery is always worrisome to the elder patients undergoing Total Hip Replacement (THR). Peripheral Nerve Blocks (PNBs), lumbar plexus block combined with sciatic nerve blocks, may be alterative anaesthesia style…
- Trial name
- NCT01782612
- Testing
- Multimodal analgesic techniques, Total uni-Hip Replacement
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Junle Liu
Emergence Delirium, Post-Operative Cognitive Dysfunction
Post Operative Cognitive Dysfunction and Delirium After Spinal Surgery
Aim of this trial is to define if Post-Operative Cognitive Dysfunction and Delirium, detected analyzing changes between pre-operative and post-operative Neurocognitive Test, relate to concentration of effector's site…
- Trial name
- NCT03950557
- Volunteers
- 200 people
- Sponsor
- University of Padova
Emergence Agitation
Propofol Versus Dexmedetomidine Effect on Prevention Emergence Agitation
The goal of this clinical trial is to compare Propofol versus Dexmedetomidine in children undergoing squint surgery. The main question it aims to answer is: Which drug is more effective in preventing the appearance of Emergence…
- Trial name
- NCT06312618
- Testing
- Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Delirium
The Neuro-epigenetics Biomarkers of Postoperative Delirium in Elderly Patients Undergoing Hip/Knee Replacement
Introduction: Postoperative delirium (POD), an acute, transient, fluctuating disturbance in attention, cognition, and level of consciousness, is a common (15-53%) postoperative complication, and it is associated with longer…
- Trial name
- NCT04923243
- Testing
- hip/knee replacement
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhongnan Hospital
Delirium in Old Age
Erector Spinae Block and Incidence of Postoperative Delirium After Hip Fracture Surgeries
Postoperative pain is a significant risk factor for delirium. This clinical trial will search whether analgesia produced by erector spinae block in elderly patients undergoing hip fracture surgeries reduces delirium or not!
- Trial name
- NCT05819723
- Testing
- CAM score
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Delirium, Postoperative Cognitive Dysfunction
Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial
The purpose of this study is to determine whether preoperative administration of Rivastigmine prevents the incidence of postoperative delirium in patients undergoing major surgery as well as postoperative cognitive dysfunction.
- Trial name
- NCT00835159
- Testing
- Rivastigmine Patch
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Delirium - Postoperative, Sleep Problems
Metabolomics and Biomarker Research on the Mechanism of Preoperative Sleep Disorders Affecting Postoperative Outcomes in Cardiac Surgery Patients
This study is titled "Metabolomics and Biomarker Research on the Mechanism of Preoperative Sleep Disorders Affecting Postoperative Outcomes in Adult Cardiac Surgery".
- Trial name
- NCT07588178
- Testing
- This is a observational study and there is no intervention.
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Yan Fuxia
Postoperative Delirium
The Effect of Transcutaneous Electrical Acupoint Stimulation Combined With Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Surgery
The aim of this clinical trial is to study the effect of transcutaneous electrical acupoint stimulation combined with auricular vagus nerve stimulation on postoperative delirium in elderly patients undergoing gastrointestinal…
- Trial name
- NCT07045090
- Testing
- Transcutaneous electrical acupoint stimulation, Transcutaneous electrical acupoint stimulation combined with auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Affiliated Hospital of Nantong University
Postoperative Delirium
Naples Prognostic Score for Predicting Postoperative Delirium
Naples Prognostic Score (NPS) originally developed to predict outcomes in inflammatory and malignant conditions; we asked if it can effectively predict postoperative delirium (POD) in elderly patients undergoing hip surgery? NPS…
- Trial name
- NCT07297017
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- South Valley University
Delirium - Postoperative, Sleep Problems
Effect of Preoperative Sleep Intervention on Postoperative Delirium in Adult Patients Undergoing Cardiac Surgery
This is a multicenter, randomized, controlled clinical trial aimed to determine whether preoperative sleep interventions could reduce the incidence of adverse outcomes, such as postoperative delirium, in adult patients undergoing…
- Conditions
- Delirium - Postoperative, Sleep Problems, CABG, Valve Surgery
- Trial name
- NCT06777342
- Testing
- Cognitive behavioral therapy intervention, Melatonin intervention
- Volunteers
- 1,281 people
- Sponsor
- Yan Fuxia
Postoperative Delirium
Modified Tian Wang Bu Xin Dan Hydrogel Patch in Preventing Postoperative Delirium in Elderly Patients
The purpose of this study is to determine whether preoperative administration of Modified Tian Wang Bu Xin Dan Hydrogel Patch prevents the incidence of postoperative delirium in elderly patients undergoing major surgery.
- Trial name
- NCT04947761
- Testing
- modified Tian Wang Bu Xin Dan hydrogel patch
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Delirium, Elderly Patient
Diagnosis, Incidence and Consequences of PACU-Delirium
This study aims to 1. determine sensitivity and specificity of the Confusion Assessment Method for Postanesthesia Care Unit (CAM-PACU) 2.
- Conditions
- Postoperative Delirium, Elderly Patient, Cognitive Decline
- Trial name
- PADE-DIC (NCT04978870)
- Where
- Germany
- Volunteers
- 450 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Postoperative Delirium
The Role of Remazolam in Reducing the Incidence of Postoperative Delirium in Elderly Patients
This study is a prospective, randomized, controlled trial.The selected patients were randomly divided into remazolam general anesthesia group and propofol + midazolam general anesthesia control group according to computer…
- Trial name
- NCT05466279
- Testing
- remazolam, Propofol, Midazolam
- Where
- China
- Volunteers
- 131 people
- Sponsor
- Fang Jun
Emergence Delirium
Dexmedetomidine-Midazolam vs. Ketamine-Midazolam on Emergence Delirium
Fifty children undergoing heart catheterization without local anesthesia in the skin will be randomly divided into two groups. Group DM (Dexmedetomidine + Midazolam) and Group KM (Ketamine + Midazolam)
- Trial name
- NCT07427446
- Testing
- Dexmedetomidine and Midazolam, Ketamine and Midazolam
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital