Clinical trials: Post-Operative Nausea and Vomiting (PONV)
Nausea, Postoperative
Does Aromatherapy Decrease Postoperative Nausea and Vomiting?
Aromatherapy has been proven to be effective for treating patients with postoperative nausea and vomiting (PONV) after surgery, but few studies analyze its effect on preventing PONV.
- Trial name
- NCT03577496
- Testing
- Peppermint oil
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Artificial Abortion, PONV(Post Operative Nausea and Vomiting)
The Time Point of Carboprost Methylate Administration and Perioperative Complications
Artificial abortion is the most widely used procedure in termination of first-trimester pregnancy. Cervical ripening before the operation guarantees operative convenience and decreases complications.
- Trial name
- NCT05834361
- Testing
- early vaginal administration of carboprost methylate, delayed vaginal administration of carboprost methylate
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Postoperative Nausea and Vomiting
Dexamethasone and Ondansetron Versus Placebo for Postoperative Nausea and Vomiting
The investigators want to test if it is indicated to associate dexamethasone and ondansetron in obese patients having bariatric surgery under total intra-venous closed-loop anesthesia.
- Trial name
- Loop-NVPO (NCT01876290)
- Testing
- Dexamethasone and Ondansetron
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Hopital Foch
Pain, Postoperative, Postoperative Nausea and Vomiting
Large-scale Prospective Double-blind Randomized Controlled Trial of Pecs II Block for Breast Surgery
In this prospective trial, Stage 1-3 patients having mastectomies or isolated lumpectomy with axillary node dissection will be randomly assigned to general anesthesia with opioids combined with a Pecs II block or to general…
- Trial name
- NCT02544282
- Testing
- Levobupivacaine, NaCl 0.9%, Sevoflurane
- Where
- Belgium
- Volunteers
- 140 people
- Sponsor
- GZA Ziekenhuizen Campus Sint-Augustinus
Postoperative Nausea and Vomiting
Efficacy Study of Antiemetics to Reduce Postoperative Nausea and Vomiting
We randomized patients who received laparoscopic surgery for benign gynecologic disease into double dose (Experimental Group) or single dose (Control Group) of antiemetics.
- Trial name
- NCT01806948
- Testing
- Ramosetron
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Seoul National University Hospital
Quality of Recovery, Urology
Postoperative Recovery and Comfort in Patients Undergoing Urologic Robotic Surgery
Previously published studies show that adding intrathecal morphine to general anesthesia can reduce the postoperative pain and length of stay (LOS) in varies types of surgery.
- Conditions
- Quality of Recovery, Urology, Pain, PONV
- Trial name
- NCT04694950
- Testing
- Usual care
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Linkoeping University
Postoperative Nausea, Postoperative Vomiting
Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
In the present study, midazolam and palonosetron in combination were more effective than palonosetron alone in lowering the incidence and severity of postoperative nausea and vomiting in the initial 2 h after laparoscopic…
- Trial name
- NCT03933605
- Testing
- midazolam and palonosetron group, palonosetron group
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Yeungnam University College of Medicine
Postoperative Nausea and Vomiting (PONV)
An Evaluation the Effect of Superhydration Versus Dextrose 10% for Prevention of Post Operative Nausea and Vomiting After Laparoscopic Cholecystectomy (Prospective Randomised Controlled Study)
The goal of this clinical trial is to learn if Dextrose 10% or superhydration works to prevent postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. .
- Trial name
- NCT06847594
- Testing
- ringer lactate (20ml/kg), Dextrose 10%
- Where
- Egypt
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cholelithiasis, Postoperative Nausea and Vomiting
A Randomized Controlled Trial Comparing the Effects of Different Anesthetic Sedatives on PONV in Laparoscopic Cholecystectomy
This study is designed to compare three sedative medications used during general anesthesia for gallbladder removal surgery (laparoscopic cholecystectomy) and their effects on nausea and vomiting after surgery.
- Trial name
- NCT07758803
- Testing
- Propofol, Ciprofol, Remimazolam
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Xi'an Aerospace General Hospital
Bariatric Surgery Candidate, Postoperative Nausea and Vomiting
Prevention of Postoperative Nausea and Vomiting After Bariatric Surgery
Postoperative nausea and vomiting are common occurrences following bariatric surgery, occurring in up to 80% of patients and contributing to increased healthcare utilization and delays in discharge.
- Conditions
- Bariatric Surgery Candidate, Postoperative Nausea and Vomiting, Morbid Obesity
- Trial name
- NCT04644445
- Testing
- Bariatric Full Liquid Diet
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Postoperative Nausea
Aprepitant for Post-operative Nausea
Anesthesia, especially for laparoscopic surgery, can cause post-operative nausea and vomiting. Most patients are given two drugs, decadron and ondansetron, to try to minimize this.
- Trial name
- NCT01020903
- Testing
- Aprepitant
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Northwell Health
Opioid Use, Pain, Postoperative
Outcome of Multimodal Anesthesia Bern
In the context of the ongoing opioid crisis in the USA and Europe, reducing perioperative opioid use is a growing priority. Multimodal anesthesia (MMA) offers a patient-centered alternative to opioid-free anesthesia, combining…
- Conditions
- Opioid Use, Pain, Postoperative, Postoperative Complications, Postoperative Nausea
- Trial name
- NCT06985069
- Testing
- General anesthesia applying multimodal anesthesia, General anesthesia using conventional opioid-based regimen
- Where
- Switzerland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Postoperative Nausea and Vomiting
Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery; Association With ABCB1 Polymorphism
Opioid-based intravenous patient-controlled analgesia (IV-PCA) offers excellent pain control, however, its use inevitably increases the incidence of postoperative nausea and vomiting (PONV).
- Trial name
- NCT02480088
- Testing
- Ramosetron, Palonosetron
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Yonsei University
Postoperative Pain, Postoperative Nausea and Vomiting
Comparison of Thoracolumbar Interfascial and Erector Spinae Plane Block on Analgesic Efficiency of After Spinal Surgery
Spinal surgery is typically associated with severe postoperative pain. Although the number of spinal surgeries has increased day by day, postoperative pain management have been limited.
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Opioid Use
- Trial name
- TALIPES (NCT03931343)
- Testing
- Bilateral 20 ml 0.25 % Bupivacaine with 2mg preservative free dexametasone and 5mcg/ml epinephrine injected between multifidus and longissimus muscle with USG guidance, Bilateral 20 ml 0.25 % Bupivacaine with 2mg preservative free dexametasone and 5mcg/ml epinephrine injected between the erector spinae muscles and transverse process with USG guidance
- Volunteers
- 60 people
- Sponsor
- Bezmialem Vakif University