Clinical trials: Post-Partum Hemorrhage
Post Partum Hemorrhage
Cervical Traction vs. Active Management of 3rd Stage of Labor
306 patients will be divided randomly in to 2 GROUPS: control group: 153 patients will receive Oxytocin 10 IU I.V shot administered at the time of delivery of the anterior shoulder of the baby for both groups in prevention of…
- Trial name
- NCT04747015
- Testing
- Oxytocin, cervical traction
- Where
- Egypt
- Volunteers
- 306 people
- Sponsor
- Cairo University
Post Partum Haemorrhage
Clinical Study to Assess the Equivalence of Tranexamic Acid vs Oxytocin in Reducing the PPH
The purpose of this study was to evaluate that the tranexamic acid (TXA)Intravenous and oral, is equivalent oxytocin (OXY),intramuscularly, in reducing the blood loss in post partum period (mL) in patients at the end of pregnancy…
- Trial name
- TRANOXY2016 (NCT02775773)
- Testing
- Tranexamic Acid, Oxytocin
- Where
- Italy
- Volunteers
- 256 people
- Sponsor
- Azienda U.S.L. 1 di Massa e Carrara
Postpartum Hemorrhage, Cesarean Section Complications
Tranexamic Acid in Patients for Caesarian Delivery.
This is a prospective, double-blinded, randomized placebo-controlled trial. The study will be approved by the DUHS institutional review board (IRB) and the trial will be registered at clinical trial registry.
- Conditions
- Postpartum Hemorrhage, Cesarean Section Complications, Obstetric Anesthesia Problems
- Trial name
- TXA; CD (NCT05759156)
- Testing
- Tranexamic acid injection
- Where
- Pakistan
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Postpartum Hemorrhage
A Program to Evaluate Riastap® and FIBTEM® for the Early Control and Treatment of Postpartum Hemorrhage (PERFECT PPH)
In this prospective, single-center, randomized, placebo-controlled, double-blind clinical trial, parturients with primary PPH are eligible for treatment with fibrinogen concentrate following both vaginal delivery and cesarean…
- Trial name
- PERFECT PPH (NCT02528708)
- Testing
- fibrinogen concentrate
- Sponsor
- Yale University
Postpartum Hemorrhage
Tranexamic Acid in Preventing Postpartum Hemorrhage in High Risk Pregnancies During Elective Cesarean Section
postpartum hemorrhage (PPT) represents one of the major causes of maternal mortality . Tranexamic acid is used in many studies in management of PPH in combination with ecobolics.
- Trial name
- NCT03351686
- Testing
- Tranexamic Acid
- Volunteers
- 140 people
- Sponsor
- Mansoura University
Post-partum Hemorrhage, Blood Transfusion
Risk Factors, Management and Complications of Severe Post-partum Hemorrhage
The incidence of severe post-partum hemorrhage has been increasing in developed countries. The reason for this is at least partially unknown.
- Trial name
- PPH-REG (NCT02815605)
- Where
- Finland
- Volunteers
- 9,000 people
- Sponsor
- Tampere University Hospital
Postpartum Hemorrhage, Postpartum Depression
Postpartum Video Education in High Risk Populations
This is a prospective, single-center, randomized control study to determine if video education at the time of postpartum discharge improves patient knowledge on the warning signs for the top three causes of severe maternal…
- Conditions
- Postpartum Hemorrhage, Postpartum Depression, Postpartum Sepsis, Postpartum Preeclampsia
- Trial name
- NCT06310720
- Testing
- Video Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Postpartum Hemorrhage, Obstetric Care
Effect of Simulation-Based Education on Knowledge, Skills, and Self-Efficacy in Postpartum Hemorrhage Management
Postpartum hemorrhage is an important obstetric emergency that requires early recognition and timely management. Midwifery students may have limited opportunities to practise postpartum hemorrhage management repeatedly in real…
- Conditions
- Postpartum Hemorrhage, Obstetric Care, Simulation Based Medical Education
- Trial name
- NCT07618442
- Testing
- Simulation-Based Postpartum Hemorrhage Management Education, Traditional Theoretical Postpartum Hemorrhage Education
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ömercan Aksoy
Postpartum Haemorrhage
Towards Better Prognostic and Diagnostic Strategies for Haemostatic Changes During Major Obstetric Haemorrhage
Major obstetric haemorrhage (MOH) remains a cause of significant maternal morbidity and mortality worldwide. By identifying women with a higher a priori risk of major haemorrhage during their pregnancy or early during postpartum…
- Trial name
- TeMpOH-2 (NCT02149472)
- Where
- Netherlands
- Volunteers
- 1,649 people, healthy volunteers welcome
- Sponsor
- Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research
Postpartum Hemorrhage
Uterine Tamponade for Treatment of Primary Postpartum Hemorrhage
Postpartum hemorrhage (PPH) is responsible for around 25% of maternal mortality worldwide reaching as high as 60% in some countries.
- Trial name
- NCT02568657
- Testing
- Celox group, Bakri Balloon
- Volunteers
- 66 people
- Sponsor
- Assiut University
Hemorrhage, Postpartum
Intrauterine Misoprostol Versus Rectal Misoprostol in Reducing Blood Loss During Cesarean Section
98 pregnant women attending for CS will be randomized into 2 groups. Rectal misopristol group who will receive 400 microgram misoprostol rectally preoperatively with urinary catheter insertion and intrauterine misopristol group…
- Trial name
- NCT03723031
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Cairo University
Blood Loss, Surgical, Postpartum Hemorrhage
Ideal Time of Oxytocin Infusion During Cesarean Section
This study will evaluate if the timing of oxytocin administration in cesarean deliveries will affect the amount of maternal blood loss.
- Conditions
- Blood Loss, Surgical, Postpartum Hemorrhage, Bleed Pregnancy, Pregnancy Related
- Trial name
- I-TOPICS (NCT03246919)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Loyola University
Postpartum Hemorrhage, Nursing Education
The Effect of Using Virtual Simulation on Students' Knowledge and Skill Levels Regarding Postpartum Hemorrhage Management
The purpose of this study is to find out whether virtual simulation helps nursing students learn how to manage postpartum hemorrhage (heavy bleeding after childbirth).
- Conditions
- Postpartum Hemorrhage, Nursing Education, Virtual Simulation
- Trial name
- NCT07912021
- Testing
- Virtual Simulation, Case Study
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Uludag University
Postpartum Hemorrhage
Prevention of Postpartum Hemorrhage With Tranexamic Acid
Postpartum hemorrhage is a significant contributor to maternal morbidity and mortality and is worldwide. TXA has recently been proven to reduce mortality when given to women in setting of diagnosed PPH.
- Trial name
- NCT03287336
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- George Washington University
Postpartum Haemorrhage
Fibrinogen Concentrate as Initial Treatment for Postpartum Haemorrhage: A Randomised Clinically Controlled Trial
Severe maternal bleeding is a serious complication of birth and causes 125.000 deaths worldwide each year. The investigators aim to investigate if early treatment with fibrinogen concentrate versus saline can reduce the incidence…
- Trial name
- FIB-PPH (NCT01359878)
- Testing
- Fibrinogen Concentrate, Isotonic Saline
- Where
- 4 sites in Denmark
- Volunteers
- 249 people
- Sponsor
- Copenhagen University Hospital at Herlev
Postpartum Hemorrhage
In-vitro Myometrial Contractility After Oxytocin Pre-exposure in Women With Advanced Maternal Age and Morbid Obesity
Women with advanced maternal age and morbid obesity, have a higher incidence of labor induction/ augmentation and cesarean section (CS), and are at a greater risk for postpartum hemorrhage (PPH).
- Trial name
- NCT01865669
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Post Partum Hemorrhage
Misoprostol Versus Oxytocin for Prevention of Post Partum Hemorrhage
Post partum Hemorrhage (PPH) is one of three main causes of death in pregnant women. Oxytocin is widely used for prevention of PPH. Some studies suggested misoprostol as an alternative treatment when Oxytocin isn't available.
- Trial name
- NCT01863706
- Testing
- Misoprostol, Oxytocin
- Where
- Iran
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hormozgan University of Medical Sciences
Postpartum Hemorrhage
Comparative Study Between the Roles of Intrauterine Misoprostol Versus the Sublingual Route for Prevention of Postpartum Blood Loss in Elective Cesarean Sections
Study design: A prospective randomized control trial was carried out at labor and delivery unit at Kasr Al Aini Hospital, Cairo University.
- Trial name
- NCT06364098
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postpartum Hemorrhage
THUMB: Multi-centre Cluster Trial for Caesarean Section Haemorrhage
The quality improvement project evaluating the delivery of a perioperative care complex intervention to improve haemorrhage-related outcomes in patients undergoing caesarean section.
- Trial name
- NCT07005349
- Testing
- Quality improvement program
- Where
- South Africa
- Volunteers
- 2,400 people
- Sponsor
- Bruce Biccard
Postpartum Hemorrhage
The Foley's Catheter Balloon to the Bleeding From Placenta Previa
Post-partum haemorrhage due to placenta previa is usually from the placental bed at the lower uterine segment and it occurs after the placenta separation.
- Trial name
- NCT02640885
- Testing
- Foley's cather ballon
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University