Clinical trials: Post-Partum Hemorrhage
Postpartum Hemorrhage
Hayman's Haemostatic Suture to Treat Severe Post-partum Haemorrhage
Post-partum haemorrhage continues to be a leading cause of maternal mortality and morbidity, accounting for more than 125 000 deaths per year across the world.
- Trial name
- HAYMAN-1 (NCT03442491)
- Testing
- Hayman's Haemostatic Suture
- Volunteers
- 90 people
- Sponsor
- Università degli Studi dell'Insubria
Postpartum Hemorrhage, Vaginal Lacerations
Tranexamic Acid for Postpartum Vaginal Laceration Hemorrhage
The necessary information was provided to the patients included in the study and their written consent was obtained.
- Trial name
- NCT07094399
- Where
- Turkey (Türkiye)
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Harran University
Postpartum Hemorrhage, Carbetocin
Timing of Carbetocin Administration in Postpartum Hemorrhage
Postpartum haemorrhage (PPH) is one of the major contributors to maternal mortality and morbidity worldwide. Active management of the third stage of labour has been proven to be effective in the prevention of PPH.
- Trial name
- NCT06776926
- Testing
- Carbetocin
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mehmet Mete Kırlangıç
Postpartum Hemorrhage
Comparing Misoprostol and Oxytocin in Uniject for Postpartum Hemorrhage (PPH) Prevention in Senegal
This is a large, community-based, cluster-randomized trial to compare routine prophylactic use of 600 mcg oral misoprostol and 10 IU oxytocin delivered by UnijectTM intramuscularly during the third stage of labor
- Trial name
- NCT01713153
- Testing
- Misoprostol, UnijectTM
- Where
- Senegal
- Volunteers
- 1,365 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Postpartum Hemorrhage, Ligation
Uterine Artery Color Doppler Parameters After Bilateral Uterine Artery Ligation
The aim of this study is to assess Uterine artery color doppler parameters after bilateral uterine artery ligation (BUAL) for Postpartum Hemorrhage.
- Conditions
- Postpartum Hemorrhage, Ligation, Color Doppler, Uterine Artery
- Trial name
- NCT05584995
- Testing
- Control group, BUAL group
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Postpartum Hemorrhage
Comparison of IV Ergonovine With IM Carboprost, With Oxytocin IV, During Cesarean Section for Failure to Progress
Patients having Cesarean section after they have been in labor for many hours bleed much more, in average twice as much, as compared with patients having an elective Cesarean section.
- Trial name
- NCT01869556
- Testing
- Oxytocin, Ergot, Carboprost
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Uterine Atony, Postpartum Hemorrhage
Oxytocin Regimen to Prevent Atony and Postpartum Hemorrhage During Vaginal Delivery: 3-arm RCT
This is a double-blind 3-arm randomized clinical trial to determine whether higher dose oxytocin regimens (compared to the standard regimen) reduce the frequency of uterine atony and postpartum hemorrhage after vaginal delivery.
- Trial name
- NCT00790062
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 1,798 people
- Sponsor
- University of Alabama at Birmingham
Labor Complication
Comparison of Routine Versus Restrictive Episiotomy in Primigravida Women at Term.
The ongoing debate over routine versus selective episiotomy in primiparous term women underscores the necessity for updated local data.
- Trial name
- NCT07796685
- Testing
- Routine Episiotomy, Restrictive Episiotomy
- Where
- Pakistan
- Volunteers
- 466 people
- Sponsor
- Muhammad Aamir Latif
Postpartum Hemorrhage (Primary)
Effect of Extracellular Calcium on Carbetocin Mediated Contractility in Human Myometrium
Postpartum hemorrhage (PPH) continues to be an increasing problem globally. Uterotonics play an essential role in the pharmacological management of uterine atony.
- Trial name
- NCT06930391
- Testing
- Oxytocin, Carbetocin, Calcium
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Cesarean Section Complications
Sublingual Misoprostol and Tranexamic Acid in Pregnant Women With Twin Pregnancy Undergoing Cesarean Section
Purpose to evaluate the effects of sublingual misoprostol with or without intravenous tranexamic acid (TA) in comparison with placebo on reducing post-partum hemorrhage in pregnant women with twin pregnancy undergoing an elective…
- Trial name
- NCT03774524
- Testing
- Misoprostol, TA
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Aswan University Hospital
Hemorrhage, Gastrointestinal Hemorrhage
HISTOACRYL® Used for Embolization of Thoracoabdominal Artery Bleeding
This observational study will collect information from adult patients in Japan who are treated with Histoacryl® to stop bleeding from arteries in the chest or abdomen, in order to better understand how well the treatment works…
- Conditions
- Hemorrhage, Gastrointestinal Hemorrhage, Hemoptysis, Postpartum Hemorrhage
- Trial name
- HEAL (NCT07753005)
- Testing
- Embolization therapy
- Where
- 11 sites in Japan
- Volunteers
- 176 people
- Sponsor
- Aesculap AG
Other Immediate Postpartum Hemorrhage, With Delivery
Inferior Vena Cava Diameter and Postpartum Hemorrhage
Excessive bleeding after normal birth or cesarean section is defined as blood loss of 1000 mL or more (clinically estimated) within 24 hours after birth. It occurs in about 5% among postpartum women.
- Trial name
- NCT03732079
- Testing
- Ultrasound
- Volunteers
- 108 people
- Sponsor
- HaEmek Medical Center, Israel
Post Partum Hemorrhage
Bilateral Uterine Artery Ligation in Reducing Incidence of Postpartum Hemorrhage in Cesarean Section
The patients were recruited from women attending labor ward to undergo cesarean section.
- Trial name
- NCT03591679
- Testing
- Oxytocin, bilateral uterine artery ligation
- Where
- Egypt
- Volunteers
- 1,070 people
- Sponsor
- Assiut University
Cesarean Section Complications
Topical Tranexamic Acid for the Prevention of Postpartum Hemorrhage in Women Undergoing Elective Cesarean Section
In hypertensive women having an elective cesarean section, the effectiveness and safety of temporary uterine packing coupled with topical tranexamic acid as an adjuvant for decreasing blood loss during delivery were compared to…
- Trial name
- NCT05072860
- Testing
- Topical tranexamic acid, : normal saline
- Volunteers
- 150 people
- Sponsor
- Aswan University Hospital
Postpartum Hemorrhage (PPH), Placental Dysfunction
Risk Factors for Postpartum Hemorrhage in Patients With Histologically Verified Placenta Accreta
This retrospective, monocentric study aims to examine risk factors for postpartum hemorrhage in women with histologically verified placenta accreta.
- Trial name
- NCT05542043
- Testing
- Data collection
- Where
- Switzerland
- Volunteers
- 2,348 people
- Sponsor
- University Hospital, Basel, Switzerland
Placenta Previa
Balloon Tamponade Vs B-Lynch In Placenta Previa
Patients were allocated to group A and B. In group A, balloon tamponade (using Foley catheter 28 Fr) was used intra-operatively to prevent post-partum hemorrhage.
- Trial name
- NCT05133167
- Testing
- Balloon Tamponade or B-Lynch
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CMH Jhelum
Anemia, Ferritin
Effect of Timing of Umbilical Cord Clamping on Haematological and Clinical Outcomes of Infants
In developing countries up to 50% of children become anemic by 12 months of age(1. Iron deficiency anemia is a major risk factor for neonatal and infantile mortality and morbidity in Pakistan.
- Conditions
- Anemia, Ferritin, Complications, Hemorrhage
- Trial name
- NCT01081977
- Testing
- Early Cord Clamping, Delayed Cord Clamping
- Where
- Pakistan
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Postpartum Complication, Postpartum Hemorrhage
Carbetocin vs Misoprostol for Postpartum Hemorrhage Prevention
Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality worldwide, particularly among women with known risk factors.
- Trial name
- NCT07353281
- Testing
- Carbetocin 100 Microgram/mL Solution for Injection, Misoprostol
- Volunteers
- 146 people
- Sponsor
- Western Galilee Hospital-Nahariya
Postpartum Hemorrhage
Tranexamic Acid and Ethamsylate For Preventing PPH in Patient Undergoing LSCS at High Risk For PPH
The aim of this study is to compare the effect of low dose of Tranexamic acid (1gm) and Ethamsylate (1gm) after prophylactic oxytocin administration versus placebo with prophylactic oxytocin given in the 2 minutes after child…
- Trial name
- NCT02604719
- Testing
- Tranexamic Acid and Ethamsylate
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ahmed Alanwar
Postpartum Fever, Ileus
Comparison of Extraperitoneal and Intraperitoneal Cesarean Technique
Cesarean section will performed via intraperitoneally and extraperitoneally. During postoperative period pain, need for analgesia, respiratory function tests, ileus, bowel movement, discharged time will be compared.
- Conditions
- Postpartum Fever, Ileus, Hemorrhage, Pain
- Trial name
- NCT02760290
- Testing
- Extraperitoneal cesarean section, Intraperitoneal cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital