Clinical trials: Post-Stroke Cognitive Impairment (PSCI), open to volunteers
Stroke, Ischemic Stroke
Detecting and Predicting Post-stroke Cognitive Impairment Using the Oxford Cognitive Screen
Cognitive problems are common after a stroke and must be identified early so that rehabilitation can be initiated to improve outcome.
- Conditions
- Stroke, Ischemic Stroke, Hemorrhagic Stroke, Intracerebral, Cognitive Dysfunction
- Trial name
- OCS-PRECISE (NCT07897916)
- Where
- 2 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- University of Copenhagen
Stroke, Cognitive Decline
Association Between Blood Pressure and Risk of PSCI
This retrospective cohort study was designed to explore the relationship between blood pressure and cognitive impairment after stroke
- Conditions
- Stroke, Cognitive Decline, Blood Pressure
- Trial name
- NCT06730711
- Where
- China
- Volunteers
- 600 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Stroke, Post-Stroke Cognitive Impairment (PSCI)
Immersive Virtual Reality in Cognitive Rehabilitation of Patients With Post-Stroke Cognitive Impairment
This pilot study aims to evaluate the feasibility of implementing immersive virtual reality (VR) in cognitive rehabilitation for adults with post-stroke cognitive impairment receiving outpatient therapy.
- Conditions
- Stroke, Post-Stroke Cognitive Impairment (PSCI), Cognitive Dysfunction, Virtual Reality Therapy
- Trial name
- NCT07125170
- Testing
- Kinesix XR on Meta Quest 3
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Post-stroke Cognitive Impairment
Edaravone Dexborneol Sublingual Tablet for the PSCI in Acute Ischemic Stroke Patients
This is a multicenter, randomized, double-blind, placebo-controlled, exploratory Phase II clinical trial. The goal of this clinical trial is to assess the safety and efficacy of edaravone dexborneol sublingual tablets for…
- Trial name
- NCT06315231
- Testing
- Edaravone dexborneol sublingual tablet
- Where
- 21 sites in China
- Volunteers
- 226 people
- Sponsor
- Simcere Pharmaceutical Co., Ltd
Post-Stroke Cognitive Impairment (PSCI), Ischemic Stroke
Evaluation of Clinical Efficacy and Mechanism of Hand Jing-Well Acupoint Transcutaneous Electrical Stimulation in Improving Post-Stroke Cognitive Impairment
This study evaluates a non-invasive electrical stimulation therapy applied to specific acupoints on the fingers (called Jing-Well points) to improve thinking and memory problems after stroke.
- Conditions
- Post-Stroke Cognitive Impairment (PSCI), Ischemic Stroke, Cognitive Dysfunction, Cognitive Disorder, Hemorrhagic Strokes
- Trial name
- NCT07736885
- Testing
- Transcutaneous Electrical Stimulation at Jing-Well Acupoints
- Where
- China
- Volunteers
- 70 people
- Sponsor
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Post-Stroke Cognitive Impairment (PSCI), Stroke
Artificial Intelligence-Based Cognitive Training in Patients With Stroke
This study would answer the following question:Does AI application-based training improve cognitive function in Patients with Stroke? The aims of this study: To investigate the efficacy of AI application-based training on…
- Conditions
- Post-Stroke Cognitive Impairment (PSCI), Stroke, Artifical Intelligence
- Trial name
- AICoRe-Stroke (NCT07452276)
- Testing
- cognifit Mobile Application for Cognitive Training, Conventional Cognitive Rehabilitation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Omima Alaa Eldin Hussein
Post-Stroke Cognitive Impairment (PSCI), Repetitive Transcranial Magnetic Stimulation (rTMS)
High-Frequency Repetitive Transcranial Magnetic Stimulation for Cognitive Improvement in Patients With Post-Stroke Cognitive Impairment
To clarify the clinical efficacy of high-frequency rTMS on patients with post-stroke cognitive impairment, fNIRS and EEG techniques were used to observe the changes in brain functional activities of patients with post-stroke…
- Conditions
- Post-Stroke Cognitive Impairment (PSCI), Repetitive Transcranial Magnetic Stimulation (rTMS), Stroke
- Trial name
- NCT07546877
- Testing
- repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Qilu Hospital of Shandong University
Stroke, Post-stroke Cognitive Impairment (PSCI)
Effect of Butyphthalide on Cognitive Level Change After Cerebral Vascular Event-a Randomized Control Trial (Be-CLEVER)
Post-stroke cognitive impairment (PSCI) refers to a clinical syndrome characterized by cognitive impairment that occurs after a stroke event and persists for at least 24 weeks.
- Trial name
- Be-CLEVER (NCT05976152)
- Testing
- dl-3-butylphthalide
- Where
- China
- Volunteers
- 3,200 people
- Sponsor
- Fudan University
Post-Stroke Cognitive Impairment (PSCI)
Electroacupuncture Treatment for Post-stroke Cognitive Impairment
Stroke is a global public health issue, and it has become a leading cause of death and disability in China. With the rapid aging of the Chinese population, its incidence rate is continuously rising.
- Trial name
- NCT07208019
- Testing
- Acupuncture
- Where
- 5 sites in China
- Volunteers
- 340 people
- Sponsor
- Ruijie Ma
Ischemic Stroke
Efficacy and Safety of Sodium Oligomannate in the Prevention of PSCI
Post-stroke cognitive impairment (PSCI) is a common complication of stroke, and seriously affect the quality of survival and the survival time in patients with stroke, PSCI is still lack of effective prevention and treatment…
- Trial name
- NCT05545605
- Testing
- Sodium oligomannate
- Where
- 2 sites in China
- Volunteers
- 116 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Stroke, Cognitive Decline
Biomarkers Related to PSCI: An fNIRS Study
This is an fNIRS study performed to identify biomarkers related to post-stroke cognitive impairment.
- Trial name
- NCT06703307
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dingqun Bai
Stroke
the Clinical Effect of TCM Sniffing Therapy Combined With Electroacupuncture in PSCI
The patients with cognitive impairment after stroke were divided into control group, electroacupuncture group, olfactory therapy group, electroacupuncture combined with olfactory therapy group, and sham group with 35 people in…
- Trial name
- NCT06313866
- Testing
- control, Electronuchal acupuncture group treatment, Smell therapy group treatment
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Hangzhou Medical College
Ischemic Stroke, Diabete Mellitus
DPP4 Inhibitor Intervention on Post-stroke Cognitive Impairment in Ischemic Stroke Patients With Type 2 Diabetes
Post-stroke cognitive impairment (PSCI) increases the risk of disability and mortality in stroke patients, thereby exacerbating the disease burden of stroke.
- Trial name
- NCT07241897
- Testing
- Sentagliptin Phosphate - single dose
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Second Affiliated Hospital of Soochow University