Clinical trials: Post-Stroke Pain
Chronic Pain, Hemiplegic Shoulder Pain
StimRouter™ for Pain Management in Post-stroke Shoulder Pain
StimRouter Neuromodulation System includes an implanted lead which provides peripheral nerve stimulation for chronic pain. Post-stroke shoulder pain patients will be the focus of this study.
- Trial name
- PSSP (NCT03093935)
- Testing
- StimRouter Neuromodulation System
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Bioness Inc
Hemiplegic Shoulder Pain
Fu's Subcutaneous Needling Treatment for Hemiplegic Shoulder Pain
The post-stroke survivors suffered from shoulder pain are very common. The investigators performed Fu's subcutaneous needling (FSN).
- Trial name
- NCT05085236
- Testing
- Fu's subcutaneous needling (FSN), Rehabilitation
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- China Medical University Hospital
Pain, Intractable, Facial Pain
CONCEPT: Crossover Efficacy Pain Trial in Motor Cortex Stimulation for Intractable Neuropathic Pain
The CONCEPT study has been designed to evaluate the safety and the efficacy of Motor Cortex Stimulation (MCS) with a new cortical lead (circular lead, eight electrodes, Medtronic Inc, Minneapolis, USA) in the treatment of…
- Trial name
- NCT00122915
- Testing
- Cortical lead, 8 electrodes (Model 2976) with Synergy neurostimulator
- Where
- 11 sites in Austria, Belgium and 2 more
- Volunteers
- 104 people
- Sponsor
- MedtronicNeuro
Pain, Spinal Cord Injury
Deep rTMS in Central Neuropathic Pain Syndromes
Pain affects up to 30% of the general population. In particular, neuropathic pain (NeP) is caused by lesion or desease affecting peripheral or central somatosensory pathways and affects 7% of the adult population.
- Conditions
- Pain, Spinal Cord Injury, Post Stroke Pain
- Trial name
- DRTMS (NCT01932905)
- Testing
- deep rTMS
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo
Stroke ( 3 Months After Onset), Stroke in Patients: New Tool to Evaluate the Impact in Their Life
Radiofrequency vs. Ultrasound Therapy for Shoulder Joint in Stroke Patients: A Comparative Clinical Trial
The purpose of the current study is to: Compare between radiofrequency (TECAR) therapy and ultrasound on Shoulder Pain, Range of Motion and Functional Outcome in Patients with stroke.
- Trial name
- TECAR (NCT07131943)
- Testing
- Radiofrequency, Ultrasound, The designed physical therapy program
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Stroke, Neuropathic Pain
Effect of Early Neuromodulation Coupled With Rehabilitation on the Prevention of Post-stroke Pain
This is a prospective clinical study to evaluate the efficacy of tDCS stimulation, coupled with conventional rehabilitation, on the development of post-stroke neuropathic pain.
- Conditions
- Stroke, Neuropathic Pain, Central Post Stroke Pain
- Trial name
- ENADA (NCT07202455)
- Testing
- Active tDCS
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hemiplegia, Stroke
The Effect of Shoulder Problems on Balance in Hemiplegic Patients
Shoulder problems are among the most common complications in hemiplegic patients and may impair shoulder biomechanics, negatively affecting mobility, transfers, and self-care.
- Trial name
- NCT07159178
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Aydın University
Stroke, Rehabilitation
The Kinesio-taping for the Prevention of Painful Shoulder and for the Functional Recovery of Upper Limb After Stroke
This RCT aims to investigate the effectiveness of the early use of Kinesio-taping (KT) together with standard physiotherapy treatment, in the prevention of the shoulder pain of the hemiplegic upper limb following a cerebral…
- Trial name
- NCT05156164
- Testing
- Kinesio Tape Group, Control Group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Stroke, Complex Regional Pain Syndrome I (CRPS I)
Mirror Therapy for Complex Regional Pain Syndrome in Stroke Patients
The goal of this clinical study is to evaluate the effectiveness of mirror therapy in treating complex regional pain syndrome (CRPS) in patients after stroke using clinical assessments, electrophysiological evaluations, and…
- Conditions
- Stroke, Complex Regional Pain Syndrome I (CRPS I), Mirror Therapy
- Trial name
- MT-CRPS-ST (NCT07537465)
- Testing
- Mirror Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Central Post Stroke Pain
Efficacy of Pain Intervention With Deep Brain Stimulation Neuromodulation
The goal of this clinical trial is to learn if deep brain stimulation (DBS) works to treat severe pain following a stroke in adults. It will also learn about the safety of deep brain stimulation.
- Trial name
- EPIONE (NCT06387914)
- Testing
- Stimulation ON, Stimulation Pseudo-ON
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Oxford
Stroke
A Study of Post-Stroke Pain and Fatigue: Clinical Evaluation and Treatment Effect
The investigators anticipate this research will shed light on metric properties of outcome measures of pain and fatigue and the effects of the combined therapy for stroke patients.
- Trial name
- NCT01913509
- Testing
- Combined Therapy of FES and BAT, Conventional Rehabilitation
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Chang Gung University
Chronic Neuropathic Pain, Post-Stroke Pain
Transcranial Magnetic Stimulation for Chronic Neuropathic Pain
Chronic neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system. It is highly prevalent, debilitating, and challenging to treat.
- Conditions
- Chronic Neuropathic Pain, Post-Stroke Pain, Trigeminal Neuralgia, Nerve Injury
- Trial name
- NCT05593237
- Testing
- High Frequency rTMS, Low Frequency rTMS
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Lower Limb Spasticity
RELIEF Study: Lower Limb Pain Relief After Injection Cycles in Adults Suffering From Lower Limb Spasticity Following Stroke
The objective of this study is to demonstrate the effect of intramuscular BoNT-A injections in relieving pain, in a broad population of patients who suffer pain as the primary problem associated with spasticity.
- Trial name
- RELIEF (NCT02020980)
- Testing
- Botulinum toxin type A
- Where
- 28 sites in Spain
- Volunteers
- 186 people
- Sponsor
- Ipsen
Post-Stroke Hemiplegic Shoulder Pain
Ultrasound-Guided Pulsed Radiofrequency Versus Phenol Neurolysis for Post-Stroke Hemiplegic Shoulder Pain
Post-stroke hemiplegic shoulder pain is a common complication that negatively affects upper limb function and quality of life. This randomized controlled trial aims to compare the efficacy and safety of ultrasound-guided pulsed…
- Trial name
- NCT07753759
- Testing
- Pulsed radiofrequency neuromodulation, Ultrasound-guided phenol neurolysis
- Volunteers
- 70 people
- Sponsor
- Assiut University
Spinal Cord Diseases, Spinal Cord Injuries
An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain
The purpose of this study is to assess the safety of the long-term use of pregabalin at doses up to 600 mg/day in patients with central neuropathic pain (post spinal cord injury pain, post stroke pain, and multiple sclerosis…
- Conditions
- Spinal Cord Diseases, Spinal Cord Injuries, Neuralgia, Pain
- Trial name
- NCT01202227
- Testing
- pregabalin
- Where
- 26 sites in Japan
- Volunteers
- 104 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Stroke
Myofascial Dysfunction in Post Stroke Shoulder Pain
Shoulder pain is extremely common after stroke and occurs in 30-70% of patients. The pain may begin as early as one week after stroke, although peak onset and severity occurs around four months, and persists into the chronic…
- Trial name
- NCT06718413
- Testing
- hyaluronidase plus saline, saline
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Johns Hopkins University
Post-stroke Spasticity
Pain During Injection With Botulinum Toxin in Post-stroke Spasticity Treatment
The aim of the study was to analyze which step of the procedure of toxin botulinum injection is the most painful between skin break-in, electric stimulation, injection and needle withdrawal.
- Trial name
- DOLOTOX (NCT03251521)
- Testing
- pain rating during injection with botulinum toxin
- Volunteers
- 46 people
- Sponsor
- University Hospital, Grenoble
Chronic Pain, Post Stroke Pain
Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain
Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but current technology is unable to reliably achieve long-term pain symptom relief.
- Conditions
- Chronic Pain, Post Stroke Pain, Phantom Limb Pain, Spinal Cord Injuries
- Trial name
- NCT03029884
- Testing
- Open-Loop DBS, Closed-Loop DBS
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Prasad Shirvalkar, MD, PhD
Stroke
The Effect of Electrical Stimulation on Impairment of the Painful Post-Stroke Shoulder
Examination of the effects of short-term use of TENS and t-NMES on passive pain-free ROM of the painful post-stroke shoulder. Treatments are compared with no stimulation.
- Trial name
- NCT03683901
- Testing
- TENS, t-NMES, No stimulation
- Volunteers
- 10 people
- Sponsor
- MetroHealth Medical Center
Stroke, Shoulder Pain
Effects of Low Frequency TENS and Therapeutic Ultrasound in Post-stroke Shoulder Pain
Brief Summary: Post-Stroke shoulder pain is a well-known complication and is responsible for the reduction in functional outcomes.
- Trial name
- NCT05931185
- Testing
- low frequency transcutaneous electrical stimulation and Therapeutic Ultrasound, Therapeutic Ultrasound, Low frequency transcutaneous electrical stimulation
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University