Clinical trials: Post-Tonsillectomy
Obstructive Sleep Apnea, Tonsillitis
Pediatric Pain Optimization After Tonsillectomy
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery.
- Conditions
- Obstructive Sleep Apnea, Tonsillitis, Pain, Procedural
- Trial name
- NCT05244226
- Testing
- Fentanyl/Hydromorphone, Methadone
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Duke University
Postoperative Pain
Tramadol Infiltration for Tonsillectomy
The purpose of this study is to evaluate the analgesic effect and IL-6 after tramadol infiltration or intravenous for tonsillectomy.
- Trial name
- NCT01636700
- Testing
- Tramadol 2mg/kg, Saline solution
- Where
- Brazil
- Sponsor
- Federal University of São Paulo
Pain
Does Montelukast Decrease Post Adenotonsillectomy Pain in Children
Objective: The purpose of the present study is to evaluate the effectiveness of preoperative Montelukast as an analgesic for adenotonsillectomy Study Design: Randomized controlled double blinded clinical trial.
- Trial name
- Montelukast (NCT02793375)
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pediatric Adenotonsillectomy, Post Operative Analgesia
Dexmedetomidine in Pediatric Tonsillectomy
The hypothesis of this study is that the administration of an intra-operative dose of dexmedetomidine will result in adequate analgesia without respiratory depression thereby resulting in an early discharge from the post…
- Trial name
- NCT01057381
- Testing
- Dexmedetomidine 0.75 mcg/kg, Morphine 50 mcg/kg, Morphine 100 mcg/kg
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Pain
Efficacy of a Nurse Telephone Follow-up on Pain Intensity After Removal of Tonsils in Children
The purpose of this study is to determine if a nurse telephone follow-up to parents of children who underwent a removal of their tonsils would be effective in reducing pain intensity, complications and resort to other healthcare…
- Trial name
- NCT01568372
- Testing
- Telephone follow-up
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Pain, Postoperative, Postoperative Hemorrhage
Effect of Bupivacaine-infused Fibrin Sealant Application on Post-tonsillectomy Pain & Hemorrhage
The purpose of this study is to evaluate the effect of combining two interventions already in use at some institutions for reducing post-operative pain following tonsillectomy or adenotonsillectomy.
- Trial name
- NCT02343263
- Testing
- Bupivacaine, Fibrin Sealant
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pain, Acute
Comparative Study Between the Effect of Diclofanic and Ketorolac in Post Tonsillectomy Pain Management
Compare between the analgesic efficacy of diclofenac sodium and ketorolac tromethamine in post-tonsillectomy pain management.and Compare between the effect of diclofenac sodium and ketorolac tromethamine on post-tonsillectomy…
- Trial name
- NCT03178539
- Testing
- diclofenac, ketorolac
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Post-tonsillectomy Analgesia, Levobupivacaine
Levobupivacaine vs Levobupivacaine + Dexmedetomidine Infiltration for Post-tonsillectomy Analgesia and Laryngospasm in Pediatric Patients
Tonsillectomy is one of the most common surgical performed procedures in children. Adenotonsillectomy surgery in pediatrics is commonly managed as an ambulatory surgery.
- Trial name
- NCT04113720
- Testing
- Levobupivacaine hydrochloride, Levobupivacaine Hydrochloride + Dexmedetomidine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Adenoid Hypertrophy, Tonsillar Hypertrophy
Metabolomic Profiling of Racial Disparity
Tonsillectomy ± adenoidectomy (T\&A) is one of the most common surgical operations with over 500,000 pediatric T\&As performed annually in the United States.
- Conditions
- Adenoid Hypertrophy, Tonsillar Hypertrophy, Surgery
- Trial name
- NCT06266429
- Testing
- Blood collection
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Nationwide Children's Hospital
Tonsillectomy
Tonsillectomy and Risk of Post-Tonsillectomy Hemorrhage
Post-tonsillectomy hemorrhage (PTH) is a feared complication to tonsillectomy. Tonsillectomy may be performed using different surgical techniques, which include both "cold" and "hot" dissection and hemostasis - but the technique…
- Trial name
- NCT05161754
- Testing
- Hemostasis
- Where
- 2 sites in Denmark
- Volunteers
- 358 people
- Sponsor
- Nordsjaellands Hospital
Stress Response
Effect of Nebulized Lignocaine on the Stress Response of Endotracheal Intubation in Pediatrics Undergoing Tonsillectomy Operation Monitored by Rise in Serum Cortisol Level Post Intubation
This randomized clinical trial aims to is examining the effect of preoperative nebulized lidocaine on the stress response to intubation, monitored by rise in serum cortisol level post intubation
- Trial name
- NCT07139730
- Testing
- Lignocaine 2% concentration solution
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Swallowing Impairment After Tonsillectomy
Evaluation of Swallowing Impairment After Tonsillectomy
the investigator will evaluate the swallowing pattern of the patients pre-operative and will follow them up at day 15 after tonsillectomy by using Careful history taking and Fiberoptic endoscopic evaluation of swallowing (FEES).
- Trial name
- NCT06927427
- Testing
- fiberoptic endoscopic evaluation of swallowing (FEES)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obstructive Sleep Apnea Syndrome
Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy
The study will evaluate the post-operative morphine-sparing effect, pain reduction, and side effects of a continuous ketamine infusion after tonsillectomy in pediatric patients.
- Trial name
- KOSATA (NCT02425202)
- Testing
- Ketamine, Saline infusion
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Suprazygomatic Maxillary Nerve Block
Ultrasound-Guided Suprazygomatic Maxillary Nerve Block as A Part of Multimodal Analgesic Regimens
Inadequate peri-operative analgesia may contribute to an increased risk of bleeding, suture dehiscence and unacceptable surgical outcomes.
- Trial name
- NCT05023239
- Testing
- UG-SZM Group
- Volunteers
- 52 people
- Sponsor
- Cairo University
Sleep Apnea, Obstructive, Child
Effect of CPAP and Adenotonsillectomy in Upper Airway Volume of Children With OSAS
Obstructive sleep apnea syndrome (OSAS) in children has high prevalence and severe complications, and its first line of treatment (adenotonsillectomy) has risk of complications.
- Conditions
- Sleep Apnea, Obstructive, Child, Continuous Positive Airway Pressure, Adenoidectomy
- Trial name
- NCT03169491
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
Pain
Intravenous Lidocaine for Post-Tonsillectomy Pain in Pediatric Patients
The purpose of this study is to determine whether giving lidocaine intravenously during and after a tonsillectomy surgery is effective in decreasing postoperative pain.
- Trial name
- NCT02595463
- Testing
- Lidocaine, Saline
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Post Surgical Pain, Analgesia
HONEY for the Treatment of POst-Tonsillectomy Pain
Double-blind, randomised, placebo controlled, single-site trial in adults to compare the effect of Manuka honey with standard of care compared to placebo with standard of care on post-tonsillectomy pain and postoperative…
- Trial name
- HONEY-POT (NCT06275698)
- Testing
- Manuka honey MGO 1000, Sugar-based syrup, thickened with sodium alginate and flavoured with honey flavouring
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- East and North Hertfordshire NHS Trust
Sleep Apnea, Obstructive
Study to Evaluate Recovery From Postoperative Pain After Sleep Apnea Surgery
The purpose of this study is to assess whether tonsillectomy and UPPP performed using the study device to treat Obstructive Sleep Apnea (OSA) symptoms in adults is associated with less postoperative pain during the 21-day…
- Trial name
- NCT00380458
- Testing
- Coblation (radiofrequency-based device)
- Where
- United States
- Sponsor
- ArthroCare Corporation
Postoperative Pain
The Efficacy of Honey on Improving the Post Surgical Course After Tonsillectomy in Children-prospective Study
The aim of this study is to investigate the effect of honey administration on pain following pediatric tonsillectomy or adenotonsilectomy.
- Trial name
- NCT03296020
- Testing
- HONEY
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel