Clinical trials: Post-Traumatic Stress Disorder
Post-Intensive Care Syndrome, Anxiety
Family and Patient Outcomes After Pediatric Intensive Care (FOREVER)
This study aims to evaluate in the Brazilian context, the impact of the implementation of a diary program on patient and family-centered outcomes after PICU discharge.
- Conditions
- Post-Intensive Care Syndrome, Anxiety, Depression, Stress Disorders, Post-Traumatic
- Trial name
- FOREVER (NCT04961697)
- Testing
- Hospital diaries
- Where
- Brazil
- Volunteers
- 431 people
- Sponsor
- D'Or Institute for Research and Education
Depressive Disorder, Major, Post Traumatic Stress Disorder
Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
The proposed study will assess the combined effect of perampanel and ketamine on the anti-depressant response in individuals with treatment resistant depression.
- Trial name
- NCT05915013
- Testing
- Ketamine, Perampanel
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Borderline Personality Disorder, Stress Disorders, Post-Traumatic
Narrative Exposure Therapy in Women With Borderline Personality Disorder and Posttraumatic Stress Disorder
Narrative Exposure Therapy (NET) is an evidence-based trauma-focussed treatment, suitable for survivors of prolonged and repeated exposure to traumatic stress and childhood adversity.
- Trial name
- NCT02517723
- Testing
- Narrative Exposure Therapy, Dialectical Behavior Therapy, Standard Inpatient Care
- Where
- Germany
- Volunteers
- 67 people
- Sponsor
- Evangelisches Krankenhaus Bielefeld gGmbH
PTSD, PTSD Symptoms
Virtual Reality Treatment for Trauma Related to COVID-19 Infection
This clinical trial aims to develop and evaluate the effectiveness of virtual reality (VR)-based exposure therapy for trauma symptoms related to COVID-19 infection.
- Trial name
- NCT07213596
- Testing
- VR Exposure Therapy, Cognitive Behavioral Therapy (CBT), Supportive Psychotherapy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Posttraumatic Stress Disorder, Insomnia
Stress, Sleep and Cardiovascular Risk
We are evaluating a model where trauma exposure and threatening environments elicit nocturnal vigilance and sleep-related fears that compromise the healthy reduction of autonomic arousal during sleep which in turn stimulates…
- Trial name
- NCT03487991
- Testing
- Personalized sleep intervention
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Howard University
Grief, Post Traumatic Stress Disorder
Building and Sustaining Interventions for Children: Task-sharing Mental Health Care in Low-resource Settings
The BASIC study will take place in Kanduyi/Bungoma South Sub-County, in western Kenya, and focuses on children orphaned by one or two parents.
- Conditions
- Grief, Post Traumatic Stress Disorder, Depression
- Trial name
- BASIC (NCT03243396)
- Testing
- Trauma-Focused Cognitive Behavioral Therapy
- Where
- Kenya
- Volunteers
- 956 people
- Sponsor
- Duke University
Cancer of Ovary, Endometrium Cancer
The Effect of Logotherapy on Mental Health in Gynecological Cancer Patients
Gynecological cancers negatively affect women's sexuality, fertility, body image, and self-perception, resulting in deterioration in their psychological health.
- Conditions
- Cancer of Ovary, Endometrium Cancer, Cervix Cancer
- Trial name
- NCT05246462
- Testing
- Logotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
PTSD - Post Traumatic Stress Disorder, taVNS
Dexmedetomidine Combined With Transcutaneous Vagus Nerve Stimulation (taVNS) Can Reduce the Incidence of PTSD in Trauma Patients After Surgery
Emergency trauma surgery patients, due to the dual stress effects of sudden trauma events (such as car accidents, falls, engineering accidents) and surgical trauma, have a significantly higher incidence of post-traumatic stress…
- Conditions
- PTSD - Post Traumatic Stress Disorder, taVNS, Dexmedetomidine
- Trial name
- NCT07813962
- Testing
- Dexmedetomidine 0.1μg/kg/h, tavns
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Affiliated Hospital of Nantong University
Critical Care
Prediction of the Post-intensive Care Syndrome
The goal of this observational study is to assess whether a screening of patients at discharge from the intensive care unit (ICU) can predict psychological and physical problems three months later.
- Trial name
- PREPICS (NCT05690438)
- Where
- 4 sites in Sweden
- Volunteers
- 773 people
- Sponsor
- Region Stockholm
Anxiety, Depression
Improving Obesity Self-Care Among Mentally Ill Veterans
The purpose of this study is to find out which of two programs, MH MOVE! or the enhanced usual care MOVE! program is most effective in improving participation in and completion of MOVE! among Veterans with depression, anxiety…
- Conditions
- Anxiety, Depression, PTSD, Obesity
- Trial name
- MH MOVE! (NCT02642536)
- Testing
- MH MOVE, Enhanced Usual Care
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- VA Office of Research and Development
Stress Disorders, Post-Traumatic
A Cognitive Behavioral Therapy and Yoga Program for Trauma Symptoms
The purpose of the proposed study is to evaluate the effectiveness of a cognitive behavioral therapy (CBT) and yoga program for improving posttraumatic stress disorder (PTSD) symptoms and sleep quality in people who have…
- Trial name
- NCT02368444
- Testing
- Cognitive Behavioral Therapy and Yoga
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Acute Stress Disorder, Post Traumatic Stress Disorder PTSD
Assessment of the Preventive Effect of Defusing on Traumatic Kindling
The exposure to a potential traumatic event (PTE) is common in the general population. This exposure may lead to psychiatric disorders such as acute stress disorder (ASD) and post-traumatic stress disorder (PTSD).
- Trial name
- PREDEKIT (NCT07850193)
- Testing
- Defusing, Psychological First Aid (PFA)
- Where
- 4 sites in France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Schizophrenia, Bipolar Disorder
Dental Status of Patients With Severe Mental Illness
The investigators aim to assess the dental status of psychiatric patients suffering from severe mental illness (schizophrenia, bipolar disorder, ptsd, resistant depression).
- Conditions
- Schizophrenia, Bipolar Disorder, PTSD, Depression
- Trial name
- SMI-DENTAL (NCT01315509)
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Hadassah Medical Organization
Psychological Distress, Quality of Life
Bright IDEAS for Pediatric Palliative Care: A Problem-Solving Skills Intervention to Empower Parent Resilience
The goal of this or clinical trial is to test in the feasibility, acceptability and preliminary efficacy of the bright IDEAS problem solving skills training for parents of children in palliative care.
- Trial name
- NCT05899998
- Testing
- Bright IDEAS
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital Los Angeles
Stress Disorders, Post-Traumatic, Mood Disorders
Preventing Long Term Psychiatric Disability Among Those With Major Burn Injuries
The purpose of this study is to determine whether a newly developed, brief cognitive behavioral intervention, relative to supportive counseling, is effective in reducing acute stress disorder (ASD) and preventing post traumatic…
- Conditions
- Stress Disorders, Post-Traumatic, Mood Disorders, Sleep Disorders
- Trial name
- SMART (NCT00988104)
- Testing
- Cognitive Behavioral Therapy, Supportive Counseling
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
PTSD, Post Traumatic Stress Disorder
High-Frequency Repetitive Transcranial Magnetic Stimulation of the Right Dorsolateral Prefrontal Cortex in PTSD
The purpose of this study is to compare two slightly different methods of transcranial magnetic stimulation (TMS) to treat Post Traumatic Stress Disorder (PTSD)
- Trial name
- rTMS (NCT02873299)
- Testing
- 10 Hz rTMS of the right dorsolateral prefrontal cortex, 20 Hz rTMS of the right dorsolateral prefrontal cortex
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Stress Disorders, Post-Traumatic
Cerebral GABA and Fear Conditioning in PTSD
Posttraumatic stress disorder (PTSD) is a common and debilitating neuropsychiatric disorder in which an acute fear response to a traumatic event does not abate.
- Trial name
- NCT01800383
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Isabelle Rosso
Posttraumatic Stress Disorder
Randomized Placebo-controlled Study of MDMA-assisted Therapy in People With PTSD - Israel
The goal of this clinical trial is to learn if MDMA-assisted therapy can treat PTSD in participants with PTSD. Researchers will compare two sessions of MDMA-assisted therapy with two sessions of low dose (active placebo)…
- Trial name
- NCT00402298
- Testing
- Full Dose Midomafetamine HCl, Low Dose Midomafetamine HCl
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- Resilient Pharmaceuticals
Posttraumatic Stress Disorder
Efficacy of Reboxetine and Methylphenidate Treatment on Attentional, Sensory and Emotional Dysregulation in Adults With PTSD
Up-to-date, no studies have examined the attentional, sensory and emotional processing (difficulties) among patients diagnosed with Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT05133804
- Testing
- Methylphenidate, Reboxetine
- Where
- 3 sites in Israel
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Posttraumatic Stress Disorder
Study of 3,4-Methylenedioxymethamphetamine-assisted Psychotherapy in People With Posttraumatic Stress Disorder
This study will examine MDMA-assisted psychotherapy in individuals aged 18 years or older diagnosed with PTSD, with PTSD symptoms not improving after trying at least one treatment.
- Trial name
- NCT00353938
- Testing
- 3,4-methylenedioxymethamphetamine (125 mg), 3,4-methyelendioxymethamphetamine (25 mg), Therapy
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- Resilient Pharmaceuticals