Clinical trials: Post-Traumatic Stress Disorder, open to volunteers
PTSD - Post Traumatic Stress Disorder
Transcranial Magnetic Stimulation in Veterans With PTSD
With this research investigators hope to begin to understand how rTMS can improve posttraumatic stress disorder (PTSD) symptoms.
- Trial name
- NCT07336251
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- White River Junction Veterans Affairs Medical Center
Post Traumatic Stress Disorder
People Bereaved by Violent Death : Negative Event Biases and Temporal Perception
A violent death is defined by its brutality, unexpectedness and is secondary to an external cause (suicide, homicide, accident).
- Trial name
- PrEVENT (NCT05874362)
- Testing
- Diagnosis of depressive episode or post traumatic stress disorder, No diagnosis of depressive episode or post traumatic stress disorder
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Hôpital le Vinatier
Post Traumatic Stress Disorder PTSD
FUS Neuromodulation for PTSD
The purpose of this study is to see if a focused ultrasound neuromodulation can be safely and effectively used to treat symptoms of PTSD
- Trial name
- NCT07900841
- Testing
- Focused Ultrasound
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- West Virginia University
Psychiatric Disorders, Depression - Major Depressive Disorder
Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital
Psychiatric conditions are each defined by different set of symptoms, however, they often share common characteristics such as impairments in cognitive and social functioning.
- Conditions
- Psychiatric Disorders, Depression - Major Depressive Disorder, Schizophrenia and Other Psychotic Disorders, Anxiety and Mood Disorders
- Trial name
- NCT07506070
- Testing
- Action-Based Cognitive Remediation
- Volunteers
- 160 people
- Sponsor
- The Royal Ottawa Mental Health Centre
PTSD - Post Traumatic Stress Disorder, Substance Use Disorder (SUD)
Mechanisms of Written Exposure Therapy in Residential SUD Treatment
The goal of this clinical trial is to learn how Written Exposure Therapy (WET), a brief treatment for PTSD, works among individuals with substance use disorders (SUD) engaged in residential SUD treatment and how biology may…
- Trial name
- NCT07397507
- Testing
- Written Exposure Therapy, Neutral Writing
- Volunteers
- 108 people
- Sponsor
- Mclean Hospital
Psychosocial Functioning, Stress Disorders, Post-Traumatic
A Mobile Health Intervention to Improve Psychosocial Functioning in Veterans With Posttraumatic Stress Disorder and Depression Symptoms
Posttraumatic stress disorder (PTSD) and depression are the two most common mental health conditions among Veterans. When Veterans experience both, there is a negative impact on their functioning, making it difficult to function…
- Conditions
- Psychosocial Functioning, Stress Disorders, Post-Traumatic, Depressive Disorder, Major
- Trial name
- NCT06689787
- Testing
- Self-Guided STAIR Coach with Real-Time Assessment, Real-Time Assessment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
PTSD
Psilocybin-Assisted Therapy
This pilot study will examine the safety, tolerability, acceptability, and efficacy of combination psilocybin + psychotherapy to decrease PTSD symptoms.
- Trial name
- NCT07332143
- Testing
- psilocybin, Supportive Therapy, Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Emory University
Thyroid Neoplasms, Neoplasm
EMDR Integrative Group Protocol and Individual Treatment for Patients With Cancer: A Pilot Study
The main aim of the present process-outcome study is to evaluate the feasibility and the effects of an EMDR-IGTP-OTS group intervention on a sample of people with cancer, by using a process-outcome study design, with repeated…
- Conditions
- Thyroid Neoplasms, Neoplasm, Post-traumatic Stress Disorder (PTSD), Psychological Distress
- Trial name
- NCT07447089
- Testing
- EMDR-IGTP-OTS
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Università Cattolica di Milano
Diagnoses of Depression, Anxiety
Improving Mental Healthcare Outcomes for Minoritized Veterans Through a Peer-led, Patient Navigation Program (PARTNER-MH 2.0)
The proposed project is a randomized controlled trial that seeks to test the effectiveness of a peer-facilitated, patient navigation program to improve mental healthcare experiences and outcomes for under-supported Veterans from…
- Conditions
- Diagnoses of Depression, Anxiety, PTSD
- Trial name
- PARTNER-MH (NCT07645274)
- Testing
- PARTNER-MH, Educational Brochure
- Where
- 2 sites in United States
- Volunteers
- 268 people
- Sponsor
- VA Office of Research and Development
PTSD, Military Activity
Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms
Art therapy is used across the Military Health System for treatment of posttraumatic symptoms, but there is limited research on how art therapy is able to restore emotional expression and regulation in service members.
- Conditions
- PTSD, Military Activity, Post-Traumatic Headache, Posttraumatic Stress Disorder
- Trial name
- NCT05414708
- Testing
- Art Therapy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Walter Reed National Military Medical Center
Brain Diseases, Epilepsy
Amygdala Memory Enhancement
The objective is to understand how amygdala activation affects other medial temporal lobe structures to prioritize long-term memories.
- Conditions
- Brain Diseases, Epilepsy, Memory Disorders, Traumatic Brain Injury
- Trial name
- NCT05065450
- Testing
- Intracranial Stimulation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Washington University School of Medicine
Dissociation
Mechanistic Interventions and Neuroscience of Dissociation
The purpose of this study is to test the neurophysiological mechanisms of an intervention to reduce symptoms of dissociation in traumatized people.
- Trial name
- MIND (NCT04670640)
- Testing
- Vibration, Breath Focus, No Distractions
- Where
- 2 sites in United States
- Volunteers
- 350 people
- Sponsor
- Emory University
Amputation, PTSD
Evacuation Time and Tourniquet Use as Risk Factors for PTSD in Combat-Related Amputation
This study aims to evaluate the relationship between evacuation time, tourniquet use, and the development of post-traumatic stress disorder (PTSD) in patients with combat-related amputations.
- Conditions
- Amputation, PTSD, Combat Posttraumatic Stess Disorder, Combat Trauma
- Trial name
- EVAC-PTSD Stud (NCT07502313)
- Where
- Ukraine
- Volunteers
- 300 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD)
Suvorexant for Treatment of AUD and PTSD
This study is to determine if suvorexant (SUV) will reduce insomnia in 76 men and women veteran and non-veterans between the ages 21-65 with posttraumatic stress disorder (PTSD) symptoms and alcohol use disorder (AUD).
- Conditions
- Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD), Insomnia
- Trial name
- SUV (NCT06679062)
- Testing
- Suvorexant
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Acute Myeloid Leukemia
Effect of Hypnosis and Virtual Reality on Anxiety During Treatment for Acute Myeloid Leukemia
This is a pilot study comparing 3 arms (standard care with hypnosis / standard care with virtual reality / standard care alone), aimed at measuring the effect on anxiety during the induction treatment.
- Trial name
- HYPNO-RV LAM (NCT07386392)
- Testing
- Hypnosis, Virtual Reality
- Where
- France
- Volunteers
- 99 people
- Sponsor
- University Hospital, Toulouse
Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms
Personalizing Treatment Delivery
Anxiety and anxiety-related disorders frequently co-occur with alcohol use problems resulting in an enormous humanitarian and economic cost to society.
- Conditions
- Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms, Alcohol; Use, Problem; Alcohol Use Disorder
- Trial name
- NCT05821634
- Testing
- Personalized intervention condition: Cognitive behavioral therapy skills, Therapeutic control condition: Cognitive behavioral therapy skills, Tracking control condition: Supportive counseling
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Rutgers, The State University of New Jersey
Schizophrenia, Psychosis
Enhancing Rehabilitation for Veterans With Serious Mental Illness
This study addresses the critical need for innovative therapeutic interventions in Veterans with serious mental illnesses (SMI) receiving care in VA Psychosocial Rehabilitation and Recovery Centers (PRRCs).
- Conditions
- Schizophrenia, Psychosis, Serious Mental Illness, PTSD
- Trial name
- NCT06586164
- Testing
- Targeted Cognitive Training
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
Moral Distress, Moral Injury
Coping and Adaptation for Recovery From Moral Injury: A Group Intervention for Clinical Psychology Residents
Moral distress may arise when health care professionals are unable to act in accordance with their professional values or believe that they have participated in, witnessed, or been unable to prevent situations that conflict with…
- Trial name
- CARE-MI (NCT07887581)
- Testing
- CARE-MI Group Intervention
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Depression, Anxiety, Post-traumatic Stress Symptoms
Predictors and Process Moderators of EMDR Therapy for Depressive Symptoms
The goal of this clinical trial is to evaluate which factors influence the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) therapy for depressive symptoms in real-world settings in Italy.
- Conditions
- Depression, Anxiety, Post-traumatic Stress Symptoms, Dissociation, Psychotherapy Research and Outcome Measures
- Trial name
- PROCESS-EMDR (NCT07033741)
- Testing
- EMDR
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Post-traumatic Stress Disorder, Prehypertension
Sympathetic Overactivity in Post-traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a highly prevalent anxiety disorder that is associated with an increased risk of cardiovascular (CV) disease and hypertension.
- Trial name
- SO-PTSD (NCT01627301)
- Testing
- Device-Guided Breathing (DGB), Transcutaneous Vagal Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Emory University