Clinical trials: Post-Traumatic Stress Disorder in Adolescence
Depression, Post-traumatic Stress Disorder
Evaluating Implementation Strategies to Scale-up Transdiagnostic Evidence-based Mental Health Care in Zambia
This study utilizes a Hybrid Type 1 multi-arm parallel group randomized control design to compare the effectiveness of an evidence-based treatment (CETA) delivered either in-person or via telephone, compared with a treatment as…
- Conditions
- Depression, Post-traumatic Stress Disorder, Anxiety, Substance Abuse
- Trial name
- NCT03458039
- Testing
- In-person CETA, Telephone CETA, Treatment as Usual (TAU)
- Where
- Zambia
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
HIV, Common Mental Health Problems
Mpata Yathu Trial for Young Women in Zambia
This randomized controlled trial evaluates Mpata Yathu ("Our Space"), a trauma-informed, church-based counseling intervention for adolescent girls and young women in Lusaka, Zambia who have experienced gender-based violence and…
- Conditions
- HIV, Common Mental Health Problems, PTSD - Post Traumatic Stress Disorder, Depression Disorder
- Trial name
- MYT (NCT07132905)
- Testing
- Mpata Yathu ("Our Space")
- Where
- 2 sites in Zambia
- Volunteers
- 180 people
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder, PTSD and Trauma-related Symptoms
TF-CBT for Autistic Youth Pilot Implementation - Open Pilot
Compared to the general population, autistic youth are at increased risk for both exposure to potentially traumatic events and trauma-related symptoms following trauma exposure.
- Conditions
- Autism Spectrum Disorder, PTSD and Trauma-related Symptoms, Autism, Trauma and Stressor Related Disorders
- Trial name
- NCT07420478
- Testing
- Trauma-Focused Cognitive Behavioral Therapy, modified for autistic youth
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
ADHD, PTSD
Trauma-adapted Yoga in Child & Adolescent Psychiatry.
The goal of this randomized clinical trial is to evaluate the efficacy of trauma-adapted yoga as a complementary intervention to care as usual in child and adolescents psychiatry clinics, in the population of adolescents with the…
- Conditions
- ADHD, PTSD, Quality of Life, Self-Control
- Trial name
- TAY-CAP (NCT06330779)
- Testing
- Trauma-adapted yoga
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- University West, Sweden
Stress Disorders, Post-Traumatic
Treatment of Post-Traumatic Stress Disorder (PTSD) in Sexually Abused Children
The purpose of this study is to compare the effectiveness of two psychological therapies used to treat PTSD in children who have recently been sexually abused: Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) vs Child…
- Trial name
- NCT00000383
- Testing
- Trauma-Focused CBT, Child-Centered Therapy
- Where
- 3 sites in United States
- Volunteers
- 229 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Post-Traumatic Stress Disorder in Children, Post-Traumatic Stress Disorder in Adolescence
Video NET With CYP Who Witnessed Domestic Violence
Research suggests that children and young people (CYP) who witness domestic violence are susceptible to develop Post-traumatic stress (PTS).
- Conditions
- Post-Traumatic Stress Disorder in Children, Post-Traumatic Stress Disorder in Adolescence, Post-Traumatic Stress Disorder Complex, Domestic Violence
- Trial name
- NCT04866511
- Testing
- Narrative Exposure Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Nottingham
Posttraumatic Stress Disorder
Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP)
The objectives of this study are to investigate the feasibility, tolerability, and preliminary efficacy of repeated ketamine-assisted psychotherapy sessions in adolescents with severe posttraumatic stress disorder.
- Trial name
- NCT06378528
- Testing
- Ketamine, SmartSleep EEG recording headband
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Wisconsin, Madison
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Symptom Assessment in Adolescents Placed on Child Welfare
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-Traumatic Stress Disorder, PTSD
- Trial name
- PePsAdoTND (NCT07794332)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Posttraumatic Stress Disorder, Attention Deficit Hyperactivity Disorder
Reminder Focused Positive Psychiatry in Adolescents With ADHD and PTSD
This feasibility study investigates the impact of reminder-focused-positive-psychiatry (RFPP) on attention-deficit-hyperactive-disorder (ADHD) and posttraumatic-stress-disorder (PTSD) symptoms, vascular-function, inflammation and…
- Trial name
- NCT04336072
- Testing
- RFPP, TFCBT
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, Los Angeles
Adolescent Behavior, Psychosocial Functioning
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
This study will deploy a scalable secondary prevention program that leverages existing foster youth transition services to improve mental health functioning and service use before and after exiting foster care.
- Conditions
- Adolescent Behavior, Psychosocial Functioning, Coping Behavior, Help-Seeking Behavior
- Trial name
- NCT06019377
- Testing
- Stronger Youth Networks and Coping (SYNC)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Portland State University
Post-Traumatic Stress Disorder in Adolescence, Post Traumatic Stress Disorder
Adolescent PCIP Randomized Feasibility Trial
There are three research questions: (1) whether the Primary Care Intervention for PTSD (PCIP) improves health outcomes; (2) whether and how the PCIP can be sustainably delivered via telehealth; and (3) how PCIP compares to…
- Trial name
- APCIP (NCT05088915)
- Testing
- Primary Care Intervention for PTSD (PCIP), Treatment As Usual
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Post-traumatic Stress Disorder (PTSD), Current Significant Sleep Disturbances
Sleep Disturbances in Children and Adolescents With Post-traumatic Stress Disorder (PTSD): a Randomized Double-blind Placebo-controlled Trial to Investigate the Efficacy of Pediatric Prolonged-release Melatonin
Among the most sensitive and persistent symptoms of post-traumatic stress disorder (PTSD) in children are sleep disturbances in the insomnia spectrum (sleep onset disturbances, fragmented sleep with multiple nocturnal awakening…
- Trial name
- MelatoSomKids (NCT07418554)
- Testing
- pediatric, prolonged released melatonin
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Strasbourg, France
Posttraumatic Stress Disorder
Trauma-Focused Cognitive Behavior Therapy for Youth: Effectiveness in a Community Setting
This effectiveness study is being conducted to determine whether Trauma-Focused Cognitive Therapy (TF-CBT), a treatment model developed in specialty clinics by experts in the treatment of child sexual abuse, can be effectively…
- Trial name
- NCT01649141
- Testing
- Trauma-Focused Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Delaware Division of Prevention and Behavioral Health Services
Grief, Post Traumatic Stress Disorder
Building and Sustaining Interventions for Children: Task-sharing Mental Health Care in Low-resource Settings
The BASIC study will take place in Kanduyi/Bungoma South Sub-County, in western Kenya, and focuses on children orphaned by one or two parents.
- Conditions
- Grief, Post Traumatic Stress Disorder, Depression
- Trial name
- BASIC (NCT03243396)
- Testing
- Trauma-Focused Cognitive Behavioral Therapy
- Where
- Kenya
- Volunteers
- 956 people
- Sponsor
- Duke University
Stress, Emotional, Stress-related Mental Disorders
School-Based Intervention to Enhance Resilience and Stress Coping in Rural Chinese Adolescents
This study aims to evaluate the effectiveness of school-based psychological interventions in improving stress resilience and coping skills among adolescents in rural China.
- Trial name
- EASY (NCT07115186)
- Testing
- Psychoeducation, guided written therapy, wait-list condition
- Where
- China
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Peking University
Posttraumatic Stress Disorder, PTSD
Girls In Recovery From Life Stress (GIRLS) Study
This study will compare treatment outcomes of 90 adolescent girls who are (a) at high risk for delinquency and/or are juvenile justice involved, and (b) who are experiencing symptoms of PTSD: 45 of the girls will receive Trauma…
- Trial name
- GIRLS (NCT00751946)
- Testing
- Trauma Adaptive Recovery Group Education and Therapy, Enhanced Treatment As Usual
- Where
- 7 sites in United States
- Volunteers
- 70 people
- Sponsor
- UConn Health
Pediatric Cancer, Follow-up Care
Coping and Post Traumatic Distress in Children and Adolescents During Cancer Follow-up Care
To explore the presence of post traumatic disorder and its association with coping strategies in children and adolescents during cancer follow-up care.
- Trial name
- NCT04908020
- Testing
- Follow-up patients
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Meyer Children's Hospital IRCCS
PTSD, Post Traumatic Stress Disorder, Adolescents
MDMA-Assisted Psychotherapy for Treatment Resistant PTSD in Adolescents
The primary objective of this study is to determine the safety and feasibility of 3,4-methylenedioxymethamphetamine (MDMA) -assisted psychotherapy to treat resistant post-traumatic stress disorder (PTSD).
- Conditions
- PTSD, Post Traumatic Stress Disorder, Adolescents, Psychotherapy
- Trial name
- NCT06353282
- Testing
- MDMA, Psychotherapy
- Where
- United States
- Sponsor
- University of California, Los Angeles
Depression and Suicide Ideation, Anxiety
Culturally Adapted Psychological Support for Conflict-Affected Afghans: Study Protocol on Mental Health & Violence
This pilot study examines the feasibility and acceptability of a culturally adapted psychological intervention-Problem Management Plus with Emotional Processing (PM+ EP)-for young Afghans aged 16-30 experiencing high…
- Conditions
- Depression and Suicide Ideation, Anxiety, PTSD
- Trial name
- NCT06980441
- Testing
- Problem Management Plus with Emotional Processing module
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Peace of Mind Association (PoMA)
PTSD
TF-CBT for Adjudicated Youth in Residential Treatment
Adjudicated youth often have traumatic stress responses but rarely receive treatment for these problems. This study is a randomized controlled trial to evaluate two alternative implementation strategies for providing an…
- Trial name
- NCT02402205
- Testing
- TF-CBT
- Volunteers
- 210 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)