Clinical trials: Post-Treatment
B-cell Lymphoma Refractory
Thiotepa, Busulfan and Fludarabin for pt With Refractory/Early Relapsed Aggressive B-cell Non Hodgkin Lymphomas
The purpose of this study is to evaluate progression free survival, transplant-related morbidity (TRM) at day +100 and at +365, overall survival and incidence of acute and chronic GVHD in refractory/early relapsed aggressive…
- Trial name
- TBF (NCT01786018)
- Testing
- Thiotepa, Busulfan, Fludarabin
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Pain, Postoperative
Intraoperative Ketamine and Magnesium Therapy for Control of Postoperative Pain After a Liposuction and Lipoabdominoplasty
Lipoabdominoplasty and liposuction are one of the most common plastic surgeries. The management of postoperative pain is complex.
- Trial name
- KEMPLA (NCT02450214)
- Testing
- Saline, Ketamine, Ketamine + magnesium
- Where
- Chile
- Volunteers
- 63 people
- Sponsor
- University of Chile
Ophthalmopathy, Wet Macular Degeneration
Reading Speed Improvements in Wet-AMD Patients After Ranibizumab Treatment
AMD (age-related macular degeneration), is the leading cause of blindness in individuals over the age of 55. There is no cure for wet-AMD but anti-VEGF treatments significantly minimize the vision loss over time.
- Trial name
- PAMER (NCT04982484)
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Patient Reported Outcome Measure
Safer Personalised Cancer Treatment Digital Follow-up
The goal of this clinical trial is to investigate patient harm/ adverse events, overall survival and health related quality of life under treatment with immunotherapy medication in cancer patients when they are followed up by a…
- Trial name
- SPecT (NCT06476158)
- Testing
- Kaiku Health
- Where
- Norway
- Volunteers
- 900 people
- Sponsor
- Nordlandssykehuset HF
Stress Disorders, Post-Traumatic; Mental Disorders
PTSD Treatment for Veterans With Serious Mental Illness to Improve Functional Outcomes
PTSD is common among Veterans with serious mental illness (SMI). Co-occurring PTSD and SMI lead to poorer mental health and physical functioning than either diagnosis alone.
- Trial name
- NCT05674617
- Testing
- Written Exposure Therapy, PTSD Education
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- VA Office of Research and Development
Post-mastectomty Seroma
Predictive Factors Affecting the Efficacy of Local Tetracycline Injection for Treatment of Post-mastectomy Seroma.
female patients with established diagnosis of post-mastectomy seroma following modified radical mastectomy, were treated by local injection of tetracycline after the seroma fluid was aspirated, then a crepe bandage was applied…
- Trial name
- NCT04730674
- Testing
- tetracycline mixed with xylocaine
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Zagazig University
Breast Cancer, Lymphedema
Hyperbaric Oxygen Therapy Compared With Standard Therapy in Treating Chronic Arm Lymphedema in Patients Who Have Undergone Radiation Therapy for Cancer
RATIONALE: Hyperbaric oxygen therapy may be effective in repairing damaged tissue and reducing lymphedema caused by radiation therapy for cancer.
- Conditions
- Breast Cancer, Lymphedema, Perioperative/Postoperative Complications, Radiation Fibrosis
- Trial name
- NCT00077090
- Testing
- hyperbaric oxygen
- Where
- 5 sites in United Kingdom
- Volunteers
- 63 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Cerebrovascular Accident, Perceptual Disorders
Effectiveness of Rehabilitation on the Recovery of Patients Post Right Stroke With Unilateral Spatial Neglect
Unilateral spatial neglect (USN) is believed to be a disorder of attention, characterized by impairment in the ability to perceive or respond to stimuli presented to the contralesional space, and which is not attributable to…
- Trial name
- NCT00305513
- Testing
- The phasic alerting treatment
- Where
- Israel
- Volunteers
- 6 people
- Sponsor
- Hadassah Medical Organization
Stroke, Healthy
fNIRS Study of Effort-dependent Brain Activations During Pointing Movements of the Upper Limb in Post-stroke Patients and Healthy Subjects
Background: Following a stroke, as part of neurorehabilitation, the intensity of effort is important to promote neural changes and stimulate motor recovery.
- Trial name
- BIROBONIRS (NCT06116006)
- Testing
- Upper limb pointing movements in 3 experimental conditions
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Clinique Les Trois Soleils
Chronic Myeloproliferative Disorders, Graft Versus Host Disease
Stem Cell Transplantation in Treating Patients With Hematologic Cancer
RATIONALE: Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy and radiation therapy used to kill tumor cells.
- Conditions
- Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma
- Trial name
- NCT00004904
- Testing
- anti-thymocyte globulin, filgrastim, cladribine
- Where
- United States
- Sponsor
- Northwestern University
Migraine
Positron Emission Tomography (PET) Study of Brain Calcitonin Gene-Related Peptide (CGRP) Receptor Occupancy After Telcagepant Administration (MK-0974-067)
The purpose of this study is to determine the receptor occupancy (RO) associated with telcagepant (MK-0974) administration based on displacement of [11C]MK-4232 from the CGRP receptors in the brain using PET.
- Trial name
- NCT01315847
- Testing
- telcagepant, [11C]MK-4232
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Temporomandibular Disorders (TMD), Temporomandibular Dysfunction (TMD)
Emotional Release After Trigger Point Needling to Treat Myofascial Pain of the Head and Neck - Prospective Study
Temporomandibular Dysfunction (TMD) as classified by the DC-TMD has a significant psychosocial component referred to as "Axis II".
- Conditions
- Temporomandibular Disorders (TMD), Temporomandibular Dysfunction (TMD), Temporomandibular Joint and Muscle Disorder
- Trial name
- NCT06912438
- Testing
- Fill out questionnaire
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cataract
Tobramycin-Dexamethasone Versus Tobramycin-Dexamethasone Plus Ketorolac After Phacoemulsification Surgery
This randomized controlled trial compares two regimens of topical therapy: tobramycin 0.3% - dexamethasone 0.1% (TobraDex®, Alcon), one drop four times/day combination of tobramycin 0.3% - dexamethasone 0.1% (TobraDex®, Alcon)…
- Trial name
- NCT00992355
- Testing
- Tobramycin 0.3% - Dexamethasone 0.1%, Tobramycin 0.3% - Dexamethasone 0.1% plus Ketorolac tromethamine 0.5%
- Where
- Greece
- Volunteers
- 97 people
- Sponsor
- Veroia General Hospital
Paroxysmal Nocturnal Hemoglobinuria
Efficacy and Safety of HRS-5965 in Patients With PNH Who Are Still Anemia After Anti-C5 Antibody Treatment
This trial is a multi-center, single-arm, open-label phase III clinical trial. A total of approximately 35 patients with paroxysmal nocturnal hemoglobinuria who remained anemic despite stable use of C5 complement inhibitor…
- Trial name
- NCT06715943
- Testing
- HRS-5965 capsule
- Where
- 2 sites in China
- Volunteers
- 39 people
- Sponsor
- Chengdu Suncadia Medicine Co., Ltd.
Acute Myeloid Leukemia (AML)
Pevonedistat and Azacitidine as Maintenance Therapy After Allogeneic Stem Cell Transplantation for Non-Remission AML
This research is being done to find out the toxicity and efficacy of a combination of Pevonedistat and Azacitidine as post allogeneic hematopoietic stem cell transplant maintenance therapy for non-remission AML and to see the…
- Trial name
- NCT03709576
- Testing
- Pevonedistat, transplant, Azacitidine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Milton S. Hershey Medical Center
Breast Cancer
Acute Post-Radiation Hyperbaric Oxygen (HBO2) for Breast Cancer Patients Who Have Recently Completed Radiation Therapy
This study aims to compare patients that receive hyperbaric oxygen or Trental and Vitamin E immediately after completion of radiation therapy to evaluate which treatment best reduces radiation fibrosis.
- Trial name
- NCT03916068
- Testing
- Hyperbaric Oxygen Therapy, Trental Pill, Vitamin E
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Legacy Health System
Trauma Centers, Trauma Patients
Assess the Efficacy of Tailored Patient Information and Voluntary Patient-managed Outpatient Digital Follow-up (I-POD) as an Adjunct to Standard Treatment According to National Guidelines in the National Trauma Plan Among Adult Trauma Patients in Norway.
The POSTRAUMA trial is a clinical trial at The Regional trauma centre of Western Norway, Haukeland University Hospital. Trauma is the leading cause of death worldwide in patients aged 1-45 years.
- Conditions
- Trauma Centers, Trauma Patients, Trauma (Including Fractures), Trauma Injury
- Trial name
- POSTRAUMA (NCT07268716)
- Testing
- The intervention is a tailored patient Information and Patient-managed Outpatient Digital follow-up treatment
- Where
- Norway
- Volunteers
- 256 people
- Sponsor
- Haukeland University Hospital
Hyperinsulinemic Hypoglycemia
Evaluating Exenatide for the Treatment of Postprandial Hyperinsulinemic Hypoglycemia
The purpose of the study is to evaluate the effectiveness of exenatide in adults experiencing episodes of hyperinsulinemic hypoglycemia following Roux-en-Y bariatric surgery.
- Trial name
- NCT02685852
- Testing
- Exenatide, Acarbose
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
Multiple Sclerosis, Relapsing
Prospective Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) After Initiation and During Treatment With Ocrelizumab
Open-label, prospective, single-arm, multi-center study to assess disease activity and biomarker of neuronal damage in minority patients (self-identified Black or African American (AA) and Hispanic/Latino (HA) patients with…
- Trial name
- NCT04377555
- Testing
- Ocrelizumab
- Where
- 28 sites in United States, Kenya and 1 more
- Volunteers
- 179 people
- Sponsor
- Genentech, Inc.
Non-small Cell Lung Cancer
Dose Escalation Of Icotinib In Previously Treated Patients With Routine Dose
To determine whether dose escalation can provide a better survival to patients who failed with icotinib at routine dose.
- Trial name
- NCT01465243
- Testing
- Icotinib
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Betta Pharmaceuticals Co., Ltd.