Clinical trials: Post-Treatment
Uterine Endometrial Cancer
Study of TUB-040 in Patients With Recurrent or Progressive Uterine Cancer After Chemotherapy and Immune Therapy
The goal of this clinical study is to learn more about the study drug TUB-040, safety, tolerability, pharmacokinetics (PK), and effectiveness in treating patients with recurrent or progressive uterine endometrial cancer after…
- Trial name
- NAPISTAR 1-03 (NCT07743541)
- Testing
- TUB-040 - Dose escalation, TUB-040 - RP2D
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Gilead Sciences
Type2 Diabetes
Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of Evogliptin 5mg and Glimepiride 4mg
A randomized, open-label, multiple dosing, three treatment, three period, two sequence clinical trial to investigate the pharmacokinetic/pharmacodynamic drug-drug interaction of evogliptin 5 mg and glimepiride 4 mg after oral…
- Trial name
- NCT02954822
- Testing
- Evogliptin→Evogliptin+Glimepiride→Glimepiride, Glimepiride→Evogliptin→Evogliptin+Glimepiride
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dong-A ST Co., Ltd.
Prostate Cancer - Recurrent, Prostate Cancer (Diagnosis)
Analysis of the Performance of PSMA Emission Tomography in Patients With Prostate Cancer Treated With HIFU
There would appear to be a strong interest in functional nuclear imaging for assessing the response to focal PaC treatment. Investigator team hypothesise that the diagnostic performance of PSMA PET is noninferior to that of MRI…
- Trial name
- ECETEP (NCT07766122)
- Testing
- Nuclear imaging (PSMA PET) with intravenous injection of a radiotracer one year after treatment (focal therapy)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Crohn's Disease
A Study of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection
The purpose of this study is to evaluate the effectiveness of guselkumab treatment compared with placebo (an inactive substance with no medicine) in preventing recurrence of Crohn's disease in participants after surgery.
- Trial name
- PROGRESS (NCT05784129)
- Testing
- Guselkumab
- Where
- 11 sites in United States, Poland
- Volunteers
- 4 people
- Sponsor
- Janssen Research & Development, LLC
Menopause
Efficacy Study of Progesterone Tablet in Post-menopausal Women
This is a phase II study intended to determine the effect of progesterone 5, 10 and 20 mg tablets compared to progesterone 100 mg capsules on the endometrial thickness of post-menopausal women under hormone therapy with estradiol.
- Trial name
- NCT02841137
- Testing
- Progesterone
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- IBSA Institut Biochimique SA
Stroke Patient
Mirror Therapy Versus Repetitive Facilitation Exercise on Upper Limb Function
The objective of the study is to determine the effects of Mirror therapy on upper limb function in a post-stroke patient, To determine the effects of Repetitive Facilitation Exercise on upper limb function in a post-stroke…
- Trial name
- NCT04468945
- Testing
- mirror box therapy, Repetitive Facilitation Exercise
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Fibromyalgia, Sexual Dysfunction
Fibromyalgia and Sexual Functıonal Dısorder and Sexual Therapy
investigators aim to re-evaluate the findings of Fibromyalgia in patients whose FSFI scores return to normal levels after sexual therapy, by identifying patients with sexual dysfunction according to the FSFI scale applied in…
- Trial name
- NCT05272345
- Testing
- sexual therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Postmenopausal Female Patients, Vasomotor Symptoms
Exercise Training Intensity and Nitrate Supplementation in Post-Menopausal Females on Hormone Therapy
This study is examining whether short-term supplementation with inorganic nitrate in the form of beetroot juice can enhance vascular function in postmenopausal females taking hormone therapy compared to placebo.
- Conditions
- Postmenopausal Female Patients, Vasomotor Symptoms, Menopausal Hormone Therapy
- Trial name
- BEET-MHT (NCT07871396)
- Testing
- Moderate Intensity Exercise (MIE), High intensity exercise (HIE), Control (No exercise)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
Atrial Fibrillation
Patient-reported Outcome Follow-up Based on the Northern Shanghai Community Chronic Disease Management System
Influence of patient-reported outcome follow-up based on the northern Shanghai community chronic disease management system on the follow-up compliance and satisfaction of patients with atrial fibrillation after cryoablation.
- Trial name
- NCT05511662
- Testing
- PRO follow up
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Shanghai 10th People's Hospital
Blood and Lymphatic Diseases
Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.
Primary Objectives: Long-term safety of BIVV003 in participants with severe sickle cell disease (SCD) and ST- 400 in participants with transfusion-dependent beta-thalassemia (TDT) Secondary Objectives: Long-term efficacy of the…
- Trial name
- NCT05145062
- Testing
- BIVV003, ST-400
- Where
- 7 sites in United States
- Volunteers
- 8 people
- Sponsor
- Sangamo Therapeutics
Non-Small Cell Lung Cancer
A Study of Chemotherapy and Ramucirumab Versus Chemotherapy Alone in Second Line Non-Small Cell Lung Cancer (NSCLC) Participants Who Received Prior First Line Platinum-based Chemotherapy
The purpose of the study is to compare the survival of participants who receive chemotherapy and ramucirumab versus chemotherapy alone as second line treatment for NSCLC after prior first line platinum-based chemotherapy.
- Trial name
- NCT01168973
- Testing
- Ramucirumab, Docetaxel
- Where
- 231 sites in United States, Argentina and 25 more
- Volunteers
- 1,253 people
- Sponsor
- Eli Lilly and Company
Non Hodgkin Lymphoma
Golcadomide and Nivolumab in Patients With Non-Hodgkin Lymphoma With Refractory Disease After Chimeric Antigen T-cell Therapy
In this combined phase I/II, open label, single arm trial to study, the safety and efficacy of combination Golcadomide and nivolumab in patients with non-Hodgkin lymphoma (NHL) who have experienced refractory/residual disease, at…
- Trial name
- NCT06767956
- Testing
- GOLCADOMIDE, Nivolumab
- Sponsor
- University of Pittsburgh
Breast Cancer
Comparing the Efficacy and Tolerability of Fulvestrant 500 mg Versus 250 mg in Advanced Breast Cancer Women
The purpose of this study is to evaluate the efficacy of a new dose of 500mg Fulvestrant with the standard dose of 250mg in Chinese postmenopausal women with oestrogen receptor positive advanced breast cancer who have failed a…
- Trial name
- NCT01300351
- Testing
- Fulvestrant
- Where
- 15 sites in China
- Volunteers
- 249 people
- Sponsor
- AstraZeneca
Post Traumatic Stress Disorder
Trauma Treatment in Norwegian Child Advocacy Centers
Norwegian child and advocacy centers´ core activities include both forensic services (e.g., forensic interviews) and follow-up services (e.g., treatment), aiming to coordinate the different services involved in each case to…
- Trial name
- NCT05314829
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT)
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Atrial Fibrillation
Anticoagulation After RFCA
The anticoagulation therapy is needed when rhythm control strategy is applied in atrial fibrillation patients but adverse events such as major bleeding exist.
- Trial name
- Reducible (NCT03573037)
- Testing
- Oral anticoagulant
- Where
- South Korea
- Volunteers
- 246 people
- Sponsor
- Yong Seog Oh
Lung Non-Small Cell Carcinoma, Positive Surgical Margin
Single Fraction Stereotactic Body Radiation Therapy After Surgery in Treating Patients With Non-small Cell Lung Cancer
This trial studies the side effects of single fraction stereotactic body radiation therapy after surgery in treating patients with non-small cell lung cancer.
- Conditions
- Lung Non-Small Cell Carcinoma, Positive Surgical Margin, Resected Mass, Stage III Lung Cancer AJCC v8
- Trial name
- NCT04073745
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Roswell Park Cancer Institute
Hypercholesterolemia
Injection Site Tolerability, Safety, Pharmacokinetics and Pharmacodynamics Study After a Single Dose Subcutaneous Treatment of Alirocumab SAR236553 (REGN727)
Primary Objective: Injection Site Tolerability Secondary Objectives: To assess the safety profile of alirocumab SAR236553 (REGN727) To assess the pharmacokinetic-pharmacodynamic relationship of alirocumab SAR236553 (REGN727)
- Trial name
- NCT01448239
- Testing
- alirocumab SAR236553 (REGN727)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sanofi
Locally Advanced Head and Neck Squamous Cell Carcinoma
Toripalimab Maintenance for Locally Advanced Head and Neck Squamous Cell Carcinoma
The guidelines for locally advanced head and neck squamous cell carcinoma currently recommend surgery / radiotherapy / chemotherapy / targeted therapy.
- Trial name
- NCT05773079
- Testing
- Toripalimab
- Volunteers
- 28 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Covid19, Cancer
Antibodies Production After Covid-19 Vaccination Among Patients With Medical History of Cancer and Anti-CD-20 Treatment
This is a Phase II study designed to investigate if the Covid 19 vaccines are capable of eliciting production of antibodies against S protein of Sar-S-Cov-2 virus among patients with medical history of cancer previously treated…
- Conditions
- Covid19, Cancer, HIV Infections
- Trial name
- NCT04779996
- Testing
- Laboratory Samples
- Where
- Puerto Rico
- Volunteers
- 250 people
- Sponsor
- Auxilio Mutuo Cancer Center
Major Depressive Disorder, Bipolar Disorder
Chart Review of Patients Undergoing Ketamine Infusions
The Canadian Rapid Treatment Center of Excellence (CRTCE) is a healthcare facility principally focused on providing best practices of intravenous ketamine treatment to adult patients suffering from mental health conditions.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder
- Trial name
- NCT04209296
- Testing
- Ketamine Hydrochloride
- Where
- Canada
- Volunteers
- 891 people
- Sponsor
- Brain and Cognition Discovery Foundation