Clinical trials: Post-acute COVID-19 Syndrome
Post Acute COVID-19 Syndrome
Effects of Immulina TM Supplements With PASC Patients
This is a multi-site study that will try to determine the effects of Immulina ™, a natural dietary supplement, on blood chemicals associated with inflammation that are often increased in patients with long COVID (also called…
- Trial name
- NCT05524532
- Testing
- Immulina TM
- Where
- 9 sites in United States, Puerto Rico
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Post-Acute COVID19 Syndrome, Long COVID
Exercise Intervention Using mHealth in Patients With Post-Acute COVID-19 Syndrome: a Randomized Clinical Trial
Post-Acute Syndrome COVID-19 is a disease resulting from infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Conditions
- Post-Acute COVID19 Syndrome, Long COVID, Post COVID-19 Condition
- Trial name
- COVIDReApp (NCT05725538)
- Testing
- COVIDReApp Group, Control Group
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Cadiz
Post COVID-19 Condition
Prospective Multidisciplinary Post-COVID-19 Registry Tyrol
Longitudinal, prospective observational cohort study enrolling patients with persisting symptoms (> 12 weeks) after COVID-19 in a multidisciplinary care model.
- Trial name
- PRECISE (NCT05545332)
- Where
- Austria
- Volunteers
- 600 people
- Sponsor
- Medical University Innsbruck
Robotic Exoskeleton, Post-acute Covid-19 Syndrome
Robotic Assisted Hand Rehabilitation Outcomes in Adults After COVID-19
Prolonged hospitalization in severe COVID-19 cases can lead to substantial muscle loss and functional deterioration. While rehabilitation is vital, conventional approaches encounter capacity constraints.
- Conditions
- Robotic Exoskeleton, Post-acute Covid-19 Syndrome, Rehabilitation Outcome, Physical And Rehabilitation Medicine
- Trial name
- NCT06137716
- Testing
- Training with a Robotic Hand Exoskeleton
- Where
- Spain
- Volunteers
- 13 people
- Sponsor
- University of Valladolid
Fatigue, Post-Acute COVID-19 Syndrome
Immunoadsorption vs. Sham Treatment in Post COVID-19 Patients With Chronic Fatigue Syndrome
The complex clinical symptoms of post COVID syndrome, especially chronic fatigue, pose a major challenge to patients and to the health care system and are frequently refractory to therapeutic intervention.
- Trial name
- NCT05954325
- Where
- Germany
- Volunteers
- 63 people
- Sponsor
- Hannover Medical School
Post COVID Condition
SuperCAP Program to Improve Cognition and Daily Functioning in Post-COVID-19 Condition
The goal of this study is to determine whether the SuperCAP intervention program is superior to control in reducing disability from baseline to the post-intervention assessment in people with Post-COVID-19 Condition.
- Trial name
- NCT07530757
- Testing
- SuperCAP intervention program, Psychoeducational intervention
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Long COVID-19 Syndrome, Post COVID Syndrome Long Covid
Inspiratory Muscle Pressure and Diaphragmatic Strength in Women With Long COVID-19: A Pressure Biofeedback-Guided Training Study
COVID-19 is an infectious disease that can cause long-term health problems even after the acute infection has resolved. Many people who have recovered from COVID-19 continue to experience breathing difficulties, fatigue, and…
- Conditions
- Long COVID-19 Syndrome, Post COVID Syndrome Long Covid, Post COVID-19 Syndrome
- Trial name
- NCT07397130
- Testing
- Pressure Biofeedback Unit
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- RSUP Persahabatan
Long COVID, Major Depressive Disorder
Presynaptic Imaging in Major Depressive Episodes After COVID-19
The goal of this observational study focuses on understanding and addressing a subset of persistent neuropsychiatric symptoms occurring within 3 months after mild to moderate COVID-19 infection (COVID-DNP).
- Conditions
- Long COVID, Major Depressive Disorder, Major Depressive Episode
- Trial name
- PCOV (NCT06086366)
- Testing
- [11C]DTBZ PET scan, [18F]SDM8 PET scan, MRI scan
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Long COVID
Qigong for Post Acute Sequelae of COVID-19 Infection
The purpose of this study is to conduct a pilot feasibility study of a combination of external and internal qigong on health-related quality of life in individuals with prolonged symptoms following COVID-19 infection.
- Trial name
- NCT05675995
- Testing
- Qigong
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Davis
COVID-19
Long-term Impact on Cardiopulmonary Function and Quality of Life in Patients Recovered From COVID-19.
FUNCTION is an observational cohort study conducted by researchers from the Instituto de Medicina Tropical Alexander von Humboldt at Universidad Peruana Cayetano Heredia and Cayetano Heredia Hospital.
- Trial name
- FUNCTION (NCT05386485)
- Testing
- None intervation
- Where
- Peru
- Volunteers
- 162 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Post-Acute COVID-19 Vaccination Syndrome, Postviral Fatigue
Clinical Laboratory Evaluation, Assessment of Symptoms and Recovery in Patients With Post-COVID-19-Vaccination Syndrome
Some people report persistent health problems after receiving the COVID-19 vaccine. These symptoms persist well beyond typical short-term vaccine side effects and are not attributable to any other known medical conditions.
- Trial name
- CLEAR (NCT07400848)
- Testing
- Blood sampling and analysis, The continuous Reactive Hyperemia Index (InRHI) measured by EndoPAT
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Bern
Post-Acute COVID-19, Post-Acute COVID-19 Infection
68Ga-FAPI PET/CT to Detect Ongoing Fibroblast Activity in Post-acute COVID-19
The goal of this observational study is to investigate the role fibroblasts play in the persistent respiratory complaints after a COVID-19 infection.
- Conditions
- Post-Acute COVID-19, Post-Acute COVID-19 Infection, Post-Acute COVID-19 Syndrome, Pulmonary Fibrosis
- Trial name
- FAPI CLIMATE (NCT05981885)
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- University Medical Center Groningen
Long Covid19, Neuropsychiatric Symptoms
Electro-acupuncture for Long Covid Neuropsychiatric Symptoms
In this study, a 16-week randomized, sham-controlled, double-blinded clinical trial will be conducted to to investigate the efficacy and safety of electro-acupuncture compared to sham acupuncture for treatment of long covid…
- Conditions
- Long Covid19, Neuropsychiatric Symptoms, Electro-acupuncture
- Trial name
- NCT05890508
- Testing
- Acupuncture
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- Hong Kong Baptist University
SARS-CoV Infection, COVID-19
Mitoquinone/Mitoquinol Mesylate as Oral and Safe Postexposure Prophylaxis for Covid-19
Adults who do not have major health, kidney, gastrointestinal disease will be randomized to receive oral mitoquinone/mitoquinol mesylate (Mito-MES) versus placebo to prevent the development and progression of COVID-19 after…
- Trial name
- NCT05886816
- Testing
- Mitoquinone/mitoquinol mesylate
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Post-Acute COVID-19 Syndrome
Probiotic Use for Recovery Enhancement From Long COVID-19
The goal of this clinical trial is to learn if probiotics can improve symptoms and quality of life in participants with Long COVID.
- Trial name
- PURE-LC (NCT06643299)
- Testing
- Probiotic Agent
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- Rush University Medical Center
Tachycardia, Dyspnea
Post-Acute Sequelae of Coronavirus-19 (COVID-19) With Dyspnea on Exertion And Associated TaChycardia TrEatment Study
Most patients with acute COVID-19 (Coronavirus 19) recover within weeks, however a significant number of individuals will develop the post-acute COVID 19 syndrome (PASC).
- Conditions
- Tachycardia, Dyspnea, COVID-19
- Trial name
- PEACE (NCT05096884)
- Testing
- Metoprolol Succinate
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Hackensack Meridian Health
Post COVID Condition
RECLAIM Adaptive Platform Trial for PCC Treatments
RECLAIM is a Phase III, multi-domain, randomized, controlled, adaptive platform trial, designed to evaluate efficacy and safety of repurposed medications in patients with post-COVID condition (PCC).
- Trial name
- RECLAIM (NCT07280572)
- Testing
- Metformin, colchicine
- Where
- Netherlands
- Volunteers
- 1,250 people
- Sponsor
- Janneke van de Wijgert
Kidney Transplant Recipients, Liver Transplant Recipients
COVID Protection After Transplant-Immunosuppression Reduction
This study will enroll individuals who have: Completed primary series of mRNA COVID-19 vaccine, and An antibody response ≤ 2500 U/mL measured at least 30 days after the last dose of vaccine.
- Trial name
- CPAT-ISR (NCT05077254)
- Testing
- Pfizer-BioNTech COVID-19 Vaccine 2023-2024, Moderna COVID-19 Vaccine 2023-2024, SOC IS Regimen
- Where
- 15 sites in United States
- Volunteers
- 48 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Post-acute COVID-19 Syndromes
The Roles of Vitamin D and Microbiome in Children With Post-acute COVID-19 Syndromes (PACS) and Long COVID
A double-blind study to evaluate the role of human microbiome and vitamin D in the development of long COVID and PACS in children.
- Trial name
- NCT05633472
- Testing
- Vitamin D
- Where
- Taiwan
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Severe COVID-19
Impact of Post-ARDS Covid-19 Sedation on Persistent Neuroinflammation
ICU Patients admitted after ARDS due to COVID infection should be weaned from invasive mechanical ventilation as quickly as possible.
- Trial name
- PET-DEXDOCOVID (NCT05233605)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris