Clinical trials: Post-anesthesia Recovery
Anesthesia
Optimizing Post-operative Recovery in Bariatric Patients With Obstructive Sleep Apnea Undergoing Outpatient Surgery: A Comparison of Sugammadex and Neostigmine
This study assesses the efficacy of sugammadex against neostigmine for hastening recovery from neuromuscular blockade and optimizing pulmonary function in obese patients with obstructive sleep apnea presenting for outpatient…
- Trial name
- NCT04570150
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, San Diego
Supratentorial Tumors
Opioid-free Anesthesia Protocol for Neurosurgical Supratentorial Tumor Resection
Opioids have many side effects, such as constipation, urinary retention, itchy skin, respiratory depression, and postoperative nausea and vomiting.
- Trial name
- NCT06607029
- Testing
- the opioid-based control group, the opioid-free anesthesia group
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Beijing Tiantan Hospital
General Anesthetics，Emergence Agitation
Advanced Analgesia on the Quality of Recovery After General Anesthesia in Elderly Patients
Recovery period of general anesthesia refers to the period from the end of anesthesia infusion to recovery of the patient after the operation.
- Trial name
- NCT05769530
- Testing
- Nalbuphine，dexmedetomidine
- Where
- 2 sites in China
- Volunteers
- 360 people
- Sponsor
- Lili Jia
Pain
The Effect of Intraoperative Esmolol to Improve Postoperative Quality of Recovery and Pain After Ambulatory Surgery
Seventy percent of surgeries performed in the United States are done in an outpatient setting.Pain Control after ambulatory surgery is very challenging because patients do not have access to fast and potent intravenous…
- Trial name
- NCT01782898
- Testing
- Esmolol administered at a rate of 0.5 mg/kg followed by an infusion of 5-15 mcg/kg/min
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Northwestern University
Colorectal Disorders, Postoperative Ileus
Does Epidural Anesthesia Reduce Postoperative Ileus Following Colorectal Surgery?
The use of epidural analgesia (EA) has been suggested as an integral part of an enhanced recovery program for colorectal surgery. However, the effects of EA on postoperative ileus remain controversial.
- Trial name
- NCT04429425
- Testing
- epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Hyperthermia, Colorectal Neoplasms
Impact of an Optimised Monitored Anesthesia on the Patients' Recovery After Cytoreduction Surgery Plus HIPEC
The objective of our PILOT study is to evaluate the impact of a controlled (monitored) randomized anesthesia during cytoreductive surgery with HIPEC to oxaliplatin in order to treat adenocarcinomas of colorectal origin.
- Conditions
- Hyperthermia, Colorectal Neoplasms, Oxaliplatin
- Trial name
- CHIPNOL (NCT04104334)
- Testing
- Remifentanil infusion, desflurane titration and fluid infusion will be guided by NOL index, BIS index and Flotrac EV1000 system respectively, Remifentanil infusion and desflurane titration will be guided by anesthesia usual practices
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Postoperative Quality of Recovery
Opioid Free Anesthesia and Bariatric Surgery
The morbidly obese bariatric surgery population is susceptible to opioid-induced complications such as respiratory depression and postoperative nausea and vomiting.
- Trial name
- NCT04144153
- Testing
- Opioid Free Total Intravenous Anesthesia, Total Intravenous anesthesia with opioid
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Northwell Health
Pain, Nausea
Quality of Recovery After Day Care Surgery With App Controlled Remote Monitoring: a Randomized Controlled Trial
Non blinded randomized controlled trial with mixed methods design. To assess the experienced quality of recovery after day care surgery between patients provided with remote home monitoring and patients receiving standard…
- Conditions
- Pain, Nausea, Vomiting
- Trial name
- QuReMo (NCT05244772)
- Testing
- Remote monitoring
- Where
- 3 sites in Netherlands
- Volunteers
- 310 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Opioid Free Anesthesia
Intraoperative Retrolaminar Block as Opioid Free Anesthesia After Posterior Lumber Spine Discectomy
Opioid-free intraoperative protocols have been successfully used in specific surgical populations with equal or superior results to classic general anesthetic approaches.
- Trial name
- NCT05312866
- Testing
- Standard analgesia (paracetamol +fentanyl), Retrolaminar block with bupivacaine + magnesium sulfate + dexamethasone
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Emergence Delirium, Emergence Agitation
Remifentanil vs Fentanyl in Children 7-12 After Urologic Surgery: Emergence Delirium and Recovery Quality
Emergence delirium (agitation) is a common complication in children recovering from general anesthesia, especially after sevoflurane.
- Conditions
- Emergence Delirium, Emergence Agitation, Anesthesia Recovery Period, Postoperative Complications
- Trial name
- NCT07800845
- Testing
- Opioids
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Konya City Hospital
Postoperative Pain, Opioid Use
Continuous Serratus Anterior Blockade for Sternotomy
This is a pilot study to assess the feasibility of a full study. The purpose is to assess the analgesic effectiveness of the serratus anterior plane (SAP) block following cardiac surgery.
- Conditions
- Postoperative Pain, Opioid Use, Quality of Life
- Trial name
- Cardiac-SAP (NCT04648774)
- Testing
- Serratus anterior plane (SAP) block
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Postoperative Residual Curarization
Comparison of Train of Four, Tetanus 50 and 100 Hz Recovery After Rocuronium Block Reversed by Neostigmine
Despite neuromuscular transmission monitoring and pharmacological reversal allowing a train of four ratio recovery higher than 0.9, patients receiving neuromuscular blocking agent during general anesthesia have a high risk of…
- Trial name
- DECURATOF 2 (NCT05224648)
- Testing
- TOF scan train of four ratio monitoring, ITF device tetanus stimulation monitoring
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Poitiers University Hospital
Hypoxemia, Postoperative Complications
Heated Humidified Oxygen in PACU Patients
This study aims to determine whether heated and humidified oxygen therapy, compared with conventional room-temperature oxygen therapy, reduces the incidence of early hypoxemia in adult patients recovering from general anesthesia…
- Conditions
- Hypoxemia, Postoperative Complications, Anesthesia Recovery Period
- Trial name
- NCT07778420
- Testing
- Heated and Humidified Oxygen Therapy, Room-Temperature Oxygen Therapy
- Where
- 8 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Pain, Acute
Effects of Transcutaneous Electrical Nerve Stimulation (TENS) Following Hysterectomy
The purpose of this study is to evaluate the effect of Transcutaneous Electrical Nerve Stimulation (TENS) in patients after abdominal hysterectomy surgery.
- Trial name
- NCT03072888
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Tokat Gaziosmanpasa University
Cardiac Surgery Intensive Care Treatment, Delayed Recovery From Anaesthesia
Role of Levothyroxine Supplementation in Delayed Recovery Following Cardiac Surgery
Research indicates that hypothyroidism decreases heart contractility, reduces stroke volume and rate, affects the vascular endothelium, and increases the risk of atherosclerosis, systemic vascular resistance, hypertension…
- Conditions
- Cardiac Surgery Intensive Care Treatment, Delayed Recovery From Anaesthesia, Euthyroid Sick Syndrome, Cardiac Surgery Requiring Cardiopulmonary Bypass
- Trial name
- L-Thyroxine (NCT06660823)
- Testing
- L-thyroxine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Flumazenil Adverse Reaction, Remimazolam
Effects of Flumazenil on Recovery After Total Intravenous Anesthesia With Remimazolam
Remimazolam is a medication that has the advantage of a short half-life and reversibility with flumazenil. In clinical situations, the use of flumazenil for the reversal of sedation is common, but there is no precise indication…
- Conditions
- Flumazenil Adverse Reaction, Remimazolam, Hip Joint, Elderly Patients
- Trial name
- NCT05939674
- Testing
- Flumazenil, normal saline
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Pusan National University Yangsan Hospital
Atelectasis, Pulmonary Infection
Bi-PAP vs Sham Bi-PAP on Pulmonary Function in Morbidly Obese Patients After Bariatric Surgery
The effect of biphasic positive airway pressure (Bi-PAP) at individualized pressures on the postoperative pulmonary recovery of morbidly obese patients (MOP) undergoing open bariatric surgery (OBS) and possible placebo…
- Conditions
- Atelectasis, Pulmonary Infection, Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Disease
- Trial name
- NCT03438383
- Testing
- Bi-PAP
- Volunteers
- 48 people
- Sponsor
- Evangelismos Hospital
Entropy Device and How Will Muscle Relaxants Affect it
Impact of Entropy Monitoring on Anesthetic Consumption and Recovery After Laparoscopic Cholecystectomy
The goal of this clinical trial is to learn if brainwave-guided anesthesia (entropy monitoring) can reduce anesthetic drug consumption and speed up recovery time in adult patients undergoing elective laparoscopic cholecystectomy…
- Trial name
- NCT07847788
- Testing
- Entropy Monitoring-Guided Anesthesia Titration, Standard Clinical Parameter-Guided Anesthesia Titration
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- KRL Hospital, Islamabad
Anesthesia, Anesthesia Recovery Period
Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Radical Prostatectomy.
Postoperative quality of recovery (QoR) could be related to anesthesia and postoperative analgesia. This study is exploring early QoR after radical prostatectomy in the two groups of anesthesia.
- Conditions
- Anesthesia, Anesthesia Recovery Period, Radical Prostatectomy, Patient Satisfaction
- Trial name
- QoR (NCT04587505)
- Testing
- Epidural anesthesia with light general anesthesia, Postoperative epidural analgesia, General anesthesia
- Where
- Croatia
- Volunteers
- 61 people
- Sponsor
- University Hospital of Split
Delayed Recovery From Anaesthesia
Measurement of Psychomotor Recovery After Anesthesia Using 4CRT
The aim of the investigation is to validate the SmartPhone-based 4-Reaction Choice Time Test (4CRT) as a measure for recovery of the psychomotor function in patients after general anesthesia.
- Trial name
- 4CRT (NCT02232139)
- Testing
- Midazolam
- Where
- Germany
- Volunteers
- 124 people
- Sponsor
- University Medicine Greifswald