Clinical trials: Post-cardiac Surgery
Postoperative Pain
Analgesic Efficacy of Transversus Thoracic Muscle Plane Block on Post-sternotomy Pain
Patients were randomly allocated to either Tansversus group (T group) and general anesthesia (N group).Patient demographic data, preoperative medical status, left ventricular function, and operative data (total ischemic time…
- Trial name
- NCT04872192
- Testing
- transversus thoracic muscle plane block, general anaesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
URTI, Postoperative Complications
Perioperative Outcomes for Children With Preoperative URTI Symptoms After COVID-19 Pandemic
The goal of this observational study is to investigate the impact of the COVID-19 pandemic on perioperative outcomes in children with preoperative URTI symptoms and to explore whether the COVID-19 pandemic affected the additional…
- Conditions
- URTI, Postoperative Complications, COVID - 19, Elective Non-cardiac Surgery
- Trial name
- URTI (NCT07157111)
- Where
- China
- Volunteers
- 2,392 people
- Sponsor
- aijun xu
Systemic Inflammatory Response Syndrome
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery
The aim of the study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of inflammatory response related complications in patients undergoing heart surgery with use of cardiopulmonary…
- Trial name
- INFLACOR (NCT01020409)
- Testing
- cardiac surgery with CPB use
- Where
- Poland
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Patients Undergoing Open Heart Surgery, Patients Undergoing Lung Surgery
CAM in Post Surgical Management in Cardiothoracic Surgery
This is a randomized controlled clinical trial in which the combination of 4 different CAM modalities (Complementary \& Alternative Medicine) will be applied during the postoperative period to patients undergoing open heart- or…
- Trial name
- NCT01650363
- Testing
- Acupuncture, homeopathy, osteopathy- and reflexology
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Shaare Zedek Medical Center
Coronary Artery Bypass, Thrombosis
Evaluating the Role of Thrombin in Saphenous Vein Graft Failure After Heart Bypass Surgery
Heart bypass surgery, also known as coronary artery bypass graft (CABG) surgery, creates a detour around the blocked part of a heart artery to restore blood supply to the heart muscle.
- Trial name
- NCT00481806
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Arizona
Glycemic Control, Surgical Site Infections
A Quality Initiative to Improve Glycemic Control in Diabetic and Non-Diabetic Insulin Study
The aim of this study is to examine the effect of moderate glucose (blood sugar) control in diabetic and non-diabetic patients undergoing leg bypass surgery (LEB) or open abdominal aortic aneurysm (AAA) repair.
- Conditions
- Glycemic Control, Surgical Site Infections, Cardiac Complications, Length of Stay
- Trial name
- NCT01916733
- Testing
- standard insulin protocol post-op (continuous IV insulin)
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Vermont Medical Center
Anxiety, Postoperative Pain
The Effect of Video-assisted Mobilisation Training on Mobility, Anxiety and Pain After Coronary Artery Bypass Surgery
This study is a Randomized Controlled trial.The aim of this study was to investigate the effect of preoperative routine patient education and video-assisted mobilization training on postoperative mobility, anxiety level and pain…
- Trial name
- NCT06117033
- Testing
- video assisted mobilization training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Namik Kemal University
Postoperative Pain
Parasternal Block and TENS for Cardiac Surgery
the objective of the present study was to compare the efficacy of TENS and parasternal block with local anesthetic infiltration in relieving pain during the first 24 h period following median sternotomy.
- Trial name
- NCT02725229
- Testing
- parasternal block, TENS group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Antalya Training and Research Hospital
Fluid Therapy, Cardiac Surgical Procedures
Internal Jugular Vein Ultrasound Measures and Fluid Responsiveness in Post-Operative Cardiac Surgical Patients
The goal of this study is to evaluate whether measures of the size of the internal jugular vein have clinical utility in predicting whether patients may benefit from treatment with intravenous fluid.
- Trial name
- NCT00500981
- Testing
- Volume challenge, Ultrasound evaluation of internal jugular vein
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Hypotension, Postoperative Complications
Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery
Major adverse cardiovascular events (MACE) are a leading cause of serious complications and death following major noncardiac surgery.
- Conditions
- Hypotension, Postoperative Complications, Acute Coronary Syndrome, Heart Failure
- Trial name
- BBB (NCT02533128)
- Testing
- Liberal blood pressure management, Tight blood pressure management
- Where
- Switzerland
- Volunteers
- 458 people
- Sponsor
- Miodrag Filipovic, Prof. Dr. med.
Atrial Fibrillation, Atrial Flutter
Pericardiotomy in Cardiac Surgery
PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Cardiac Events
- Trial name
- PRINCE (NCT06486636)
- Testing
- Left Posterior Pericardiotomy
- Where
- 19 sites in United States, Austria and 3 more
- Volunteers
- 1,400 people
- Sponsor
- Population Health Research Institute
Thoracic Surgery, Cardiopulmonary Bypass
Variations of the Lung Compliance During Extracorporeal Circulation and Post Operative Pulmonary Complications
the decrease in thoracopulmonary compliance after cardiac surgery is well known . The investigators hypothesize that the major factor determining pulmonary outcome after cardiac surgery is the alteration of pulmonary compliance…
- Trial name
- COMPLI (NCT02654600)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Atrial Fibrillation
Effect of Venous Cannulation on the Incidence of Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass
Context Atrial fibrillation is the most frequent arrhythmia following coronary artery bypass grafting. POAF is associated with worse outcomes following CABG.
- Trial name
- NCT04641611
- Testing
- Bicaval cannulation, Cavoatrial cannulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Dr. Jean-Francois Morin
Myocardial Ischemia, Coronary Artery Bypass Surgery
Humanin Isoforms in Cardiac Muscle and Blood Plasma and Major Complications After Cardiac Operation
Objective of the study is to clarify humanin-like peptide concentration in myocard tissue and in blood and to study if its concentration level is related to early complication occurrence and frequency after cardiac operation.
- Trial name
- NCT03431844
- Where
- 2 sites in Estonia
- Volunteers
- 106 people
- Sponsor
- University of Tartu
Coronary Artery Disease
The MASS COMM Post-Randomization Phase Cohort Study
The primary objective of the Post-Randomization Phase Cohort Study is to continue to assess the safety of non-emergency PCI performed at hospitals without cardiac surgery on-site in patients with myocardial ischemia (other than…
- Trial name
- NCT02072421
- Testing
- PCI
- Where
- 10 sites in United States
- Volunteers
- 2,879 people
- Sponsor
- Baim Institute for Clinical Research
Healthcare Associated Infectious Disease, Sternal Superficial Wound Infection
Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery
Our Aim is to identify patient risk factors and clinical practices associated with healthcare-acquired infections (HAIs) after cardiac surgery.
- Conditions
- Healthcare Associated Infectious Disease, Sternal Superficial Wound Infection, Sepsis, Pneumonia
- Trial name
- HAI (NCT02068716)
- Where
- United States
- Volunteers
- 911,754 people
- Sponsor
- Dr. Donald Likosky
Machine Learning, Acute Kidney Injury
Machine Learning Predict Renal Replacement Therapy After Cardiac Surgery
Cardiac surgery-associated acute kidney injury (CSA-AKI) is a major complication which may result in adverse impact on short- and long-term mortality.
- Conditions
- Machine Learning, Acute Kidney Injury, Renal Replacement Therapy, Prediction Models
- Trial name
- NCT04977687
- Where
- China
- Volunteers
- 2,108 people
- Sponsor
- Chinese PLA General Hospital
Tricuspid Atresia, Hypoplastic Left Heart Syndrome
Biomarker Study for Heart Failure in Children With Single Ventricle Physiology
The purpose of this study is to determine if children with heart disease where there is only one pumping chamber("ventricle") have proteins (biomarkers") in the blood that can be used to monitor the function of their heart.
- Conditions
- Tricuspid Atresia, Hypoplastic Left Heart Syndrome, Unbalanced AV Canal
- Trial name
- BHFSVP (NCT00571233)
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of California, San Francisco
Thrombosis
Risk of Developing Antibodies to Heparin-PF4 After Heart Surgery
Heparin is a drug that is widely used to prevent and treat blood clotting. Individuals undergoing cardiopulmonary bypass surgery are administered high doses of heparin, and some of them develop antibodies to the drug.
- Trial name
- HIT (NCT00237328)
- Testing
- Heparin
- Where
- 4 sites in United States
- Volunteers
- 1,015 people
- Sponsor
- Duke University
Pulmonary Complication, Postoperative Complications
ARISCAT and LAS VEGUS Risk Scores for Predicting Postoperative Pulmonary Complications After Cardiac Surgery
The goal of this observational study is to compare the, ARISCAT and LAS VEGUS scales, for predicting postoperative pulmonary complications in patients undergoing cardiac surgery.
- Conditions
- Pulmonary Complication, Postoperative Complications, Postoperative Pulmonary Complications
- Trial name
- NCT06173583
- Testing
- Detection/screening
- Where
- Pakistan
- Volunteers
- 181 people
- Sponsor
- Aga Khan University