Clinical trials: Post-cardiac Surgery
Vasoplegic Syndrome, Vasoplegia
Analysis of miRNAs Expression in Vasoplegic Syndrome After On-pump Coronary Artery Bypass Surgery
This study looks for a correlation between microRNAs (miRNAs) and vasoplegic syndrome after on-pump coronary artery bypass surgery.
- Conditions
- Vasoplegic Syndrome, Vasoplegia, Surgery-Complications, Surgery
- Trial name
- PREVENT (NCT05354193)
- Testing
- vasoplegic syndrome
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- University of Sao Paulo General Hospital
Abdomen, Acute, Myocardial Injury
MINS, AKI and Pulmonary Pathology in Patients Undergoing Acute Abdominal Surgery
Explorative study to investigate potential predictors of myocardial injury, acute kidney injury and pulmonary disorder after acute high-risk abdominal surgery.
- Conditions
- Abdomen, Acute, Myocardial Injury, Acute Kidney Injury, Pulmonary Disease
- Trial name
- NCT04681508
- Testing
- Chest CT without contrast enhancement and chest X-ray
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Nordsjaellands Hospital
Antimicrobial Stewardship, Cardiovascular Surgeries
Evaluation of the Potential Impact of Computerized Antimicrobial Stewardship
This trial is an open-label, two-arm, cluster-randomized, controlled trial with cardiovascular surgical teams as the unit of randomization.
- Conditions
- Antimicrobial Stewardship, Cardiovascular Surgeries, Computerized Decision Support System, Coronary Artery Disease
- Trial name
- EPIC (NCT04328090)
- Testing
- Computer based Antimicrobial stewardship (AMS) intervention system
- Where
- China
- Volunteers
- 2,473 people
- Sponsor
- China National Center for Cardiovascular Diseases
Congenital Heart Disease
The Efficacy of Systematic Oral Feeding Education Program
After the intervention of Systematic Oral Feeding Education Program: 1. The feeding techniques scores of the main caregivers in the experimental group will be higher than those in the control group. 2.
- Trial name
- SOFEP (NCT06763497)
- Testing
- Systematic Oral Feeding Education Program
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Cardiac Surgery
Transversus Thoracis Plane Block Versus Parasternal Intercostal Nerve Plane Block for Cardiac Surgery
Traditionally postoperative pain management after cardiac surgery has been based on opiate analgesics. However, opiates have some undesirable dose-related side-effects such as nausea, constipation, vomiting, dizziness, mental…
- Trial name
- NCT06155097
- Testing
- transversus thoracis muscle plane block (TTP), parasternal intercostal nerve block (PSI block)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Zagazig University
Cardiovascular Disease
Usefulness of Integrative Medicine Tools As Adjunctive Care for Women After Coronary Artery Bypass Grafting
Background: This randomized controlled trial investigates the effectiveness of an Integrative Therapies (IT) health education intervention in improving physical and psychological functioning in female patients after coronary…
- Trial name
- NCT01020227
- Testing
- Integrative Therapies Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Columbia University
Acute Kidney Injury, Renal Insufficiency, Acute
Effects of Levosimendan in Acute Kidney Injury After Cardiac Surgery
Acute kidney injury (AKI) is a common complication after cardiac surgery. Mismatch in renal oxygen demand-supply may be an important pathogenetic factor.
- Trial name
- LEVOAKI (NCT02531724)
- Testing
- Levosimendan
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Sahlgrenska University Hospital
Laryngeal Injury, Swallowing Disorder
Laryngeal Disorders After Childhood Cardiac Surgery
Laryngeal disorders after childhood cardiac surgery is a complication well described in the literature. However, the long term progression of the affected children has never been studied (all the studies stopped before 2 years of…
- Conditions
- Laryngeal Injury, Swallowing Disorder, Voice Disorders in Children, Surgery--Complications
- Trial name
- RECUP-TML (NCT04638361)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Hospices Civils de Lyon
Hypertrophic Obstructive Cardiomyopathy \(HOCM\), Neurologic Evaluation
Neurologic Evaluation of Patients After Transapical Beating-Heart Septal Myectomy
The goal of this prospective cohort study is to evaluate the neurologic changes in patients that received transapical beating-heart septal myectomy.
- Conditions
- Hypertrophic Obstructive Cardiomyopathy \(HOCM\), Neurologic Evaluation, Magnetic Resonance Imaging \(MRI\), Transapical Beating-Heart Septal Myectomy
- Trial name
- NCT06078410
- Testing
- Cardiac surgery
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xiang Wei
Analgesia After Coronary Artery Bypass Graft Surgery
Regional Blocks for CABG Artery Bypass Graft Surgery
Pain control after CABG is an essential step to guard against postoperative complications such as lung atelectasis. This major step can be achieved by opioids or regional blocks.
- Trial name
- NCT05691920
- Testing
- Pectointercostal plane block and external oblique intercostal plane block, Fentanyl infusion
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Coronary Artery Disease, Coronary Stenosis
Enhanced Recovery After Surgery (ERAS) in Coronary Artery Bypass Graft / Off Pump Coronary Artery Bypass (CABG/OPCAB)
It has been assumed that some elements of the ERAS protocol may contribute to the reduction of complications and improve the satisfaction of patients undergoing coronary artery bypass surgery.
- Trial name
- NCT03956420
- Testing
- Premedication visit, Preoperative period, Postoperative period
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Silesian University of Medicine
Cardiac Arrhythmias
Documentation of Cardiac Arrhythmias After Open Heart Surgery
This study aims at recording cardiac arrhythmias in patients after open heart surgery. The arrhythmias will be monitored during the entire first postoperative period, till six weeks after surgery.
- Trial name
- NCT02657590
- Volunteers
- 200 people
- Sponsor
- Ziv Beckerman MD
Myocardial Injury After Non-cardiac Surgery
Preoperative BNP and MINS in AAA Open Repair
The aim of this study was to investigate whether preoperative B-type natriuretic peptides serves as an independent predictor of myocardial injury after non-cardiac surgery (MINS) in abdominal aortic aneurysm open repair.
- Trial name
- NCT06088641
- Testing
- preoperative BNP value
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- Gangnam Severance Hospital
Coronary Artery Disease
Haptoglobin Polymorphism as a Determinant of Adverse Outcome After Cardiac Surgery in Diabetic Patients
Specific aim 1a will test the hypothesis that diabetic patients with 2-2 haptoglobin genotype have higher indices of postoperative myocardial injury (creatine kinase MB isoenzyme , Troponin I ) and renal injury (as indicated by…
- Trial name
- NCT02771808
- Testing
- biomarker samples
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- University of Virginia
Coronary Bypass Graft Stenosis, Valvular Heart Disease
Comparison of Post-operation Cardiopulmonary Capacity of Patients Underwent Conventional and Robot-assisted Coronary Artery Bypass Graft and Valve Replacement Surgery
Robotic surgery is one of the most popular minimally invasive procedures for patients with coronary artery disease or valvular diseases.
- Trial name
- NCT05430568
- Testing
- robot-assisted surgery
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taichung Veterans General Hospital
Cardiac Surgery, Enhanced Recovery After Surgery
The Application of Enhanced Recovery After Surgery (ERAS) for Cardiovascular Surgery in Adult
Among adults, patients undergoing elective extracorporeal circulation for cardiac surgery are included in the ERAS strategy intervention plan, which mainly includes preoperative education, preoperative oral intake of…
- Trial name
- NCT05914090
- Testing
- ERAS
- Where
- 2 sites in China
- Volunteers
- 3,600 people
- Sponsor
- Yan Fuxia
Bypass Complications
Transcutaneous-Arterial Carbon Dioxide and Microcirculatory Dysfunction
Evaluation of the microcirculation is currently limited. Continual assessment of the tissue carbon dioxide-arterial carbon dioxide (PtC02-aCO2) offers a new, novel and noninvasive method of determining the state of the…
- Trial name
- NCT02328846
- Sponsor
- University of Virginia
Fluid Overload, Cardiac Surgery
Fluid Responsiveness in Post-cardiac Surgery
the study aims to examine the validity of combined end-expiratory and end-inspiratory occlusion test and tidal volume challenge test for prediction of fluid responsiveness in immediate post-cardiac surgery patients
- Conditions
- Fluid Overload, Cardiac Surgery, Postoperative Complications
- Trial name
- NCT05957003
- Testing
- Combined end-expiratory occlusion and end-inspiratory occlusion test, Tidal volume challenge test
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Coronary Artery Bypass Grafting, Heart Diseases
The Short Form-36: Pre- Versus Post-Surgical Administration in Cardiac Surgery Patients
The purpose of this study is to determine whether the SF-36 can be administered reliably to cardiac surgery patients (two to three days) post-surgery, with the patient answering the questions of this survey from a pre-surgical…
- Conditions
- Coronary Artery Bypass Grafting, Heart Diseases, Heart Valve Diseases
- Trial name
- NCT00226265
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Weill Medical College of Cornell University
Single Ventricle Heart Disease After Fontan Surgery
Pharmacokinetic/Pharmacodynamic Study of Udenafil in Adolescents
To determine the pharmacokinetic profile and safety of udenafil in adolescents with Fontan physiology and to assess the short-term pharmacodynamic effect of udenafil on pharmacodynamic measures of exercise capacity, ventricular…
- Trial name
- NCT02201342
- Testing
- Udenafil
- Where
- 6 sites in United States, Canada
- Volunteers
- 36 people
- Sponsor
- Mezzion Pharma Co. Ltd