Clinical trials: Post-cardiac Surgery Patients
Atrial Fibrillation
Study of T3 on the Incidence of Atrial Fibrillation in Patients Undergoing Cardiac Surgery
The purpose of this project is to see whether treatment with a thyroid hormone, called triiodothyronine or T3, following open heart surgery reduces the risk of developing atrial fibrillation.
- Trial name
- NCT00289367
- Testing
- Triiodothyronine
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Northwell Health
Post Cardiac Surgery Patients
Measurement of Cardiac Output and Blood Volumes Using Transonic Ultrasound Dilution Technology
Measurement of the amount of blood pumped by the heart (cardiac output) and blood volumes in sick patients is important for doctors to better treat these patients.
- Trial name
- NCT00756119
- Where
- Russia
- Volunteers
- 26 people
- Sponsor
- Transonic Systems Inc.
Cardiac Valve Disease, Coronary Artery Disease
Telehealth Interventions for Cardiac Surgery
The goal of this clinical trial is to compare telehealth monitoring at home against usual care in patients undergoing planned heart surgery. The main questions it aims to answer are: 1.
- Conditions
- Cardiac Valve Disease, Coronary Artery Disease, Surgical Complication
- Trial name
- TICS (NCT05621954)
- Testing
- Telehealth Monitoring
- Where
- United Kingdom
- Volunteers
- 318 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Coronary Artery Disease, Anemia
Clinical and Chemical Outcomes Following Cardiac Surgery: The Post-Operative Effects of MUF
It is hypothesized that on-line modified ultrafiltration (MUFF) post-cardiopulmonary bypass will result in improved patient outcomes over the 12-hour post-operative period as compared to control and off-line MUFF.
- Trial name
- MUF (NCT01864395)
- Testing
- Centrifugation Method, Online MUF, Offline MUF
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Saskatchewan
Atrial Fibrillation, Subclinical Hyperthyroidism
Is a Low Thyreotropin Level Predictive of Recurrent Arrhythmia After Catheter Ablative Surgery?
Overt hyperthyroidism (so-called "goiter" in lay language) is a hormonal disturbance that is known to increase the risk of atrial fibrillation (a common heart arrhythmia with potentially severe consequences) in some patients.
- Trial name
- TABLAS (NCT01789541)
- Where
- 2 sites in Sweden
- Volunteers
- 327 people
- Sponsor
- Karolinska Institutet
Cardiac Surgery, Inflammation
Impact of Ascorbic Acid on Post-Cardiothoracic Surgery Inflammation
The purpose of this study is to see if ascorbic acid (Vitamin-C) therapy will reduce inflammation following heart surgery.
- Trial name
- AFIST (NCT00519337)
- Testing
- Ascorbic acid
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Hartford Hospital
Fluid Therapy, Cardiac Surgical Procedures
Internal Jugular Vein Ultrasound Measures and Fluid Responsiveness in Post-Operative Cardiac Surgical Patients
The goal of this study is to evaluate whether measures of the size of the internal jugular vein have clinical utility in predicting whether patients may benefit from treatment with intravenous fluid.
- Trial name
- NCT00500981
- Testing
- Volume challenge, Ultrasound evaluation of internal jugular vein
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Aortic Valve Disease
Health Status of Patients After Surgically Implanted Biological and TAVI: a Population-based Retrospective Analysis
The overall project aim is to study outcomes following aortic valve replacement with surgically implanted bioprostheses or TAVI by retrieving data from the main social security carriers in Austria for the years 2010-2020.
- Trial name
- NCT05912660
- Testing
- Aortic Valve Replacement
- Volunteers
- 18,882 people
- Sponsor
- Medical University of Vienna
Telehealth, Coronary Artery Bypass Surgery
The Effectiveness of a Telehealth Program on Cardiac Symptom Distress, Self-care and Quality of Life of Patients With Coronary Artery Disease After Coronary Artery Bypass Surgery: A Randomized Study
The goal of this randomized trial is to compare the outcomes of a telehealth program with conventional discharge care for patients aged 18 years and older with coronary artery disease following coronary artery bypass surgery.
- Trial name
- NCT06648291
- Testing
- QOCA EKG Device, Usual Care
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Acute Respiratory Distress Syndrome
Extravascular Lung Water and Pulmonary Vascular Permeability After Minimally Invasive Cardiac Surgery
The use of cardiopulmonary bypass (CPB) combined with one lung ventilation (OLV) allows to perform minimally invasive cardiac surgery (MICS) through small incisions.
- Trial name
- NCT02155387
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Freiburg
Post-discharge Outcomes
Retrospective Observational Study of Patients Who Have Undergone Coronary Artery Bypass Graft (CABG) and/or Cardiac Valve Surgery
This study is a retrospective chart abstraction for subjects who were enrolled in REN-004. As a retrospective study, all data will be abstracted from the medical records.
- Trial name
- NCT07009340
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Renibus Therapeutics, Inc.
Hemostatic Disorders
Blood Products Transfusion in Cardiac Surgery After the Implementation of a Coagulation Monitoring System at Patient Bedside: Thromboelastometry Versus Standard Transfusion Protocol
Main objective: Determine whether by introducing thromboelastograph, the investigators reduced the number of packed red cells received by each patient (median) compared to the usual protocol, in which the indication for…
- Trial name
- ROTEM-2010 (NCT01919840)
- Testing
- Group ROTEM, Group C
- Volunteers
- 49 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Gut Microbiota, Postoperative Pulmonary Complications
Gut Microbiota and Pulmonary Complications After Non Cardiac Elective Surgery in Elderly Patients
An observational cohort was established using preoperatively collected biospecimens and prospectively ascertained postoperative outcomes.
- Trial name
- NCT06513416
- Testing
- Elective abdominal surgery
- Where
- China
- Volunteers
- 265 people
- Sponsor
- Peking Union Medical College Hospital
Post-operative Delirium, Major Non-cardiac Surgery
MIND After Surgery
Delirium is the most common neurological adverse outcome in elderly surgical patients. It is associated with an increased mortality and morbidity, including need for prolonged hospital stay and institutional care.
- Trial name
- MIND (NCT03785158)
- Testing
- Liquid Melatonin
- Where
- 2 sites in Canada
- Volunteers
- 88 people
- Sponsor
- McMaster University
Post-Op Complication
Perioperative Smart Device Monitoring to Predict Complications
This is a prospective, single-center, observational study designed to to quantify complications following non cardiac intermediate and high-risk surgery, and to identify digital biomarkers (collected pre, and post-operatively by…
- Trial name
- PreSmart (NCT06156033)
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Peak Expiratory Flow Rate, Coronary Artery Bypass Graft Surgery
Additional Effects of Flutter With Conventional Chest Physiotherapy on Peak Expiratory Flow Rate and Chest Expansion in Post CABG Patients With COPD
Flutter therapy is an oscillating positive expiratory pressure (OPEP) technique that combines positive expiratory pressure with airway oscillations to facilitate mobilization and clearance of respiratory secretions.
- Conditions
- Peak Expiratory Flow Rate, Coronary Artery Bypass Graft Surgery, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT07875049
- Testing
- Conventional Chest Physiotherapy, Flutter device with conventional chest physiotherapy
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Foundation University Islamabad
After Cardiac Surgery, Diuretic Resistance
Evaluation of the Efficacy of rhBNP in Patients With Diuretic Resistance After Cardiac Surgery
evaluation of the efficacy of recombinant human brain natriuretic peptide in patients with diuretic resistance after cardiac surgery: a prospective single-center single-blind randomized controlled study
- Trial name
- rhBNP (NCT07086287)
- Testing
- rhBNP and standard basic treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Coronary Artery Bypass Grafting (CABG) Surgery
Individualized Orem-Based Nursing Intervention After Coronary Artery Bypass Grafting
This randomized controlled trial will evaluate the effectiveness of an individualized self-care and nursing intervention program based on Orem's Self-Care Theory among patients following coronary artery bypass grafting (CABG).
- Trial name
- CABG-OREM (NCT07839598)
- Testing
- Individualized Nursing Intervention Program Based on Orem's Self-Care Theory, Usual postoperative care
- Where
- Jordan
- Volunteers
- 440 people
- Sponsor
- Jerash Private University
Heart Valve Diseases
Bedside Cycling Exercises Post Heart Valve Surgeries
The aim of this clinical trial is to assess the effect of early bedside cycling exercises post heart valve surgeries. the main question aims to answer: whether adding an early bedside cycling exercise will have an effect on…
- Trial name
- NCT05893433
- Testing
- Bedside cycling, control
- Where
- Egypt
- Volunteers
- 41 people
- Sponsor
- Cairo University
Cardiac Surgery, Mechanical Ventilation After Surgery
Prevalence and Clinical Impact of Airway Opening Pressure in Post-Cardiac Surgery Patients
Airway opening pressure is a key parameter in assessing respiratory mechanics. Current practice primarily relies on indirect assessments of lung mechanics, but growing evidence suggests that direct airway opening pressure…
- Trial name
- NCT07189026
- Testing
- Airway opening pressure
- Where
- Canada
- Volunteers
- 196 people
- Sponsor
- Laval University