Clinical trials: Post-cardiac Surgery Patients
Sepsis, Post Cardiac Surgery Low Output Syndrome Requiring Inotropic/Vasopressor Therapy
Comparison of Central Venous Oxygen Saturation Measurements by Non-invasive Mespere Venous Oximeter and Central Venous Catheter
The intent of this study is to validate the venous blood oxygenation measurements of the Mespere VA Oximeter compared to the saturations measured by venous blood sampling through an inserted central vein catheter, which is…
- Conditions
- Sepsis, Post Cardiac Surgery Low Output Syndrome Requiring Inotropic/Vasopressor Therapy, Cardiogenic Shock Post Myocardial Infarction, Hypoxemic Respiratory Failure.
- Trial name
- NCT01788956
- Testing
- Mespere Venous Oximeter, Co-Oximeter
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Mespere Lifesciences Inc.
Analgesia
Bilateral Transversus Thoracic Muscle Plane Block as Analgesic in Open Heart Surgeries by US.
OPEN CARDIAC SURGERY may cause severe postoperative pain and promote a high risk of chronic pain if not treated adequately, that is caused by multiple factors; sternotomy, costotransverse and costovertebral joint distensions…
- Trial name
- NCT04116554
- Testing
- 0.25% bupivacaine., 0.9%saline
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Patients Undergoing Valvular Heart Surgery
A Prediction Model for 1-year Mortality After Valvular Heart Surgery
The investigators aimed to develop a predictive model for mortality incorporating nutritional, inflammatory, and perioperative factors in patients undergoing valvular heart surgery.
- Trial name
- NCT05833256
- Where
- South Korea
- Volunteers
- 2,046 people
- Sponsor
- Yonsei University
Respiratory Failure
Comparison of Non-invasive Methods of Lung Ventilation in Patients With Respiratory Failure After Cardiac Surgery
Comparison of the effectiveness of three methods of non-invasive ventilation in patients with mild and moderate respiratory failure in the early postoperative period after cardiac surgery
- Trial name
- NCT04787666
- Testing
- Using of non-invasive mask ventilation, high-flow oxygen therapy through a nasal cannula (high-flow nasal oxygenation) and non-invasive ventilation with a helmet
- Where
- Russia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Petrovsky National Research Centre of Surgery
Cardiac Surgery, Extracorporeal Circulation
RRI Compared With NephroCheckTM to Predict Acute Renal Failure After Cardiac Surgery.
Postoperative acute renal failure is a frequent complication after cardiac surgery. The current practice cannot predict Acute Kidney Injuries (AKI) early enough to reduce a significant kidney assault and prevent an organic…
- Conditions
- Cardiac Surgery, Extracorporeal Circulation, Nephrocheck, Renal Failure
- Trial name
- NCT02325726
- Testing
- Renal Resistive Index compared with NephroCheckTM
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Bordeaux
Post Operative Atrial Fibrillation
Prevention of Post-OP AFib Using Combination of CardiaMend and Amiodarone
The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing isolated cardiac arterial bypass…
- Trial name
- CAMP POAF (NCT05681182)
- Testing
- CardiaMend with the Addition of Amiodarone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- WakeMed Health and Hospitals
Post Induction Hypotension, Postoperative Morbidity
Preoperative Carotid Doppler Ultrasound Parameters for Prediction of Post-Induction Hypotension in Elective Non-Cardiac Surgery
This prospective observational study aims to evaluate the predictive value of preoperative carotid Doppler ultrasound parameters, including carotid velocity-time integral (carotid VTI) and corrected carotid flow time (ccFT), for…
- Trial name
- NCT07488182
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Necmettin Erbakan University
Post Operative Patient, Patients Requiring PCA
Evaluation of EverOn™ System in Medical / Surgical Ward
The EverOn™ system developed by EarlySense, Ltd., the sponsor of this study, is intended to assist hospitals to better address and improve recognition and response to changes in a patient's condition.
- Conditions
- Post Operative Patient, Patients Requiring PCA, Respiratory Patients, Patients in Risk of Fall
- Trial name
- NCT00640718
- Where
- United States
- Sponsor
- EarlySense Ltd.
Hemodynamic Instability
Hemodynamic Effect of Dexmedetomidine Alone With Dexmedetomidine Plus Ketamine Combination in CABG
In post cardiac surgery, many cardiovascular and other complications may occur that lead to increase in mortality and hospital stays. Meticulous perioperative management is important to avoid these adverse events.
- Trial name
- NCT05218161
- Testing
- Dexmedetomidine alone
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Chaudhry Pervaiz Elahi Institute of Cardiology
Limb Edema, Surgical Site Infections
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients.
- Conditions
- Limb Edema, Surgical Site Infections, Leg Swelling, Compression Bandages
- Trial name
- PEACCE (NCT06603961)
- Testing
- CPG-EB group
- Where
- 2 sites in Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Pulmonary Atelectasis, Morbid Obesity
Use of Airway Pressure Release Ventilation in Morbidly Obese Patients Undergoing Open Heart Surgery
The goal of this Randomized Clinical trial is to to investigate if the use of Air Pressure Release Ventilation in morbidly obese patients undergoing open heart surgery will improve post operative pulmonary outcomes 60 Patients…
- Conditions
- Pulmonary Atelectasis, Morbid Obesity, Pulmonary Complication
- Trial name
- NCT05670483
- Testing
- Use Of APRV mode of Ventilation, Use of conventional Synchronized Intermittent Mandatory Ventilation (SIMV) volume control mode
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Arrythmia
Effect of Sedative Agent on Reducing the Frequency of Arrhythmia in the Patients After Cardiac Surgery
Arrhythmias early in the recovery period after cardio thoracic surgery are common they develop in 11 to 40 percent of patients after coronary-artery bypass grafting.
- Trial name
- NCT05450497
- Testing
- Propofol, Dexmedetomidine, Dexmedetomidine and propofol
- Where
- Ukraine
- Volunteers
- 356 people
- Sponsor
- Anesthesia Research Group UA
Surgery--Complications, Cardiac Valve Disease
Prevention of Acute Kidney Injury by N-Acetylcystein in Patients Undergone Cardiac Valve Replacement
This is a randomized clinical trial, double-blind, placebo-controlled study with the goal to assess the influence of using N-AcetylCysteyn (NAC) for prevention of AKI (Acute Kidney Injury) in post operatory of valve replacement…
- Conditions
- Surgery--Complications, Cardiac Valve Disease, Acute Kidney Injury, Oxygen Radical Damage
- Trial name
- NCT03440268
- Testing
- N Acetyl Cysteine
- Where
- Brazil
- Volunteers
- 154 people
- Sponsor
- University of Sao Paulo General Hospital
Postoperative Atrial Fibrillation, Cardiac Tamponade
Posterior Pericardiotomy for Prevention of POAF After Cardiac Surgery: RCT in Yemen
A single-center, randomized controlled trial in Yemen evaluating whether posterior pericardiotomy (PP) reduces postoperative atrial fibrillation (POAF) after open-heart surgery.
- Trial name
- PP-POAF (NCT07266935)
- Testing
- Posterior Pericardiotomy, Standard Care
- Where
- Yemen
- Volunteers
- 210 people
- Sponsor
- Taiz University - Faculty of Medicine
Heart Valve Surgery
Effect Of Bioelectric Therapy On Sternal Instability In Patients With Median Sternotomy After Heart Valve Surgery
The aim of this study is to investigate the effect of bioelectric therapy on sternal instability in patients with median sternotomy after heart valve surgery.
- Trial name
- SI (NCT04949581)
- Testing
- bioelectric therapy, cardiac rehabilitation program
- Volunteers
- 40 people
- Sponsor
- Cairo University
Aortic Valve Disease
Health Status of Patients After Surgically Implanted Biological and Mechanical Aortic Valves: a Population-based Retrospective Analysis (2010-2018)
The overall project aim is to study outcomes following aortic valve replacement with either mechanical valves or bioprostheses by retrieving data from the main social security carriers in Austria for the years 2010-2018.
- Trial name
- NCT04900909
- Testing
- Aortic Valve Replacement
- Volunteers
- 13,993 people
- Sponsor
- Medical University of Vienna
Coronary Artery Disease
SAPT Versus DAPT in Incomplete Revascularization After CABG
The study aims to compare the efficacy of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) in patients with incomplete revascularization after coronary artery bypass graft surgery (CABG).
- Trial name
- SDAT-IRC (NCT03789916)
- Testing
- Ticagrelor, acetylsalicylic acid
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Campus Bio-Medico University
Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
A Comparison Between 5% Albumin and 6% Hydroxyethyl Starch 130/0.4 in Priming Solution for Cardiopulmonary Bypass and Post-bypass Maintenance Fluid in High-risk Patients
It is advantageous to use 5% human albumin (HA) in patients undergoing cardiopulmonary bypass (CPB), because preexposure of the synthetic surfaces of the CPB circuit to albumin decreases coagulopathy, platelet aggregation, immune…
- Trial name
- NCT01644084
- Testing
- Hydroxyethyl starch 130/0.4
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Yonsei University
Hemodynamics, Patient Monitoring
Assessment of Fluid Responsiveness in Patients After Cardiac Surgery
To overcome the limited accuracy of functional hemodynamic parameters such as stroke volume and pulse pressure variation (SVV and PPV) during spontaneous breathing, a Passive Leg Raising (PLR) manoeuvre has been suggested as a…
- Trial name
- POP (NCT02571465)
- Testing
- Passive leg raising test and fluid challenge
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Triemli Hospital
Acute Kidney Injury, Heart Transplant Surgery
Humanin's Value for Early Diagnosis and Short-term Prognosis in Patients With AKI After Heart Transplantation
The goal of this observational study is to explore the value of Humanin for early diagnosis and short-term prognosis of AKI patients after heart transplantation.
- Trial name
- NCT06125249
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Li zhilian