Clinical trials: Post-cardiac Surgery Patients
Intensive Care Unit Delirium, Cardiac Surgery
Delirium After Cardiac Surgery in Intensive Care Units
STUDY SUMMARY STUDY DESIGN The study will be conducted over twelve months in the Cardiac Intensive Care Unit (ICU) at Hammersmith Hospital, Imperial College Healthcare NHS Trust (ICHT).
- Conditions
- Intensive Care Unit Delirium, Cardiac Surgery, Post Operative Delirium
- Trial name
- DaCsi-ICU (NCT06355570)
- Testing
- Personal Pictures, Family Videos, Family Videos - Intervention as required
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College Healthcare NHS Trust
Postoperative Delirium (POD), Postoperative Sleep Disturbance
Effects of Esketamine on the Incidence of Postoperative Delirium and Postoperative Sleep Disturbance in Elderly Patients After Major Non-cardiac Surgery
Postoperative delirium (POD) is a common surgical complication.It is associated with a range of negative outcomes such as delayed postoperative recovery,prolonged hospitalization,additional medical expenditures and higher…
- Trial name
- EPISODE (NCT06900205)
- Testing
- Esketamine, 0.9 % saline
- Where
- China
- Sponsor
- RenJi Hospital
Frailty, Surgery
Cardiac Rehabilitation and Frailty Physical Training Program in Elderly Patients After Open Heart Surgery
The aim of the research - to evaluate the impact of interactive physical therapy tools for functional capacity, fear of falls, motivation and quality of life after open heart surgery due to ischemic heart disease and frailty in…
- Trial name
- NCT06385041
- Testing
- Multicomponent training group, Computer-based interactive training group
- Where
- Lithuania
- Volunteers
- 153 people
- Sponsor
- Vitalija Stonkuvienė
Post Coronary Artery Bypass Grafting, Post-Cardiac Surgery Patients
Effect of Respiratory Trainer on Cardiopulmonary Functions in Patients with Upper Cross Syndrome Post-Cardiac Surgery
The purpose of this study is to investigate if there is any effect of the respiratory training on cardiopulmonary functions in patients with upper cross syndrome post-cardiac surgery.
- Conditions
- Post Coronary Artery Bypass Grafting, Post-Cardiac Surgery Patients, Upper Cross Syndrome, Respiratory Muscle Weakness
- Trial name
- NCT06673953
- Testing
- Respiratory Muscle Training by (The Breather), Traditional physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Postoperative Ileus (Post Cardiac Surgery Constipation)
Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery
Postoperative ileus, defined as the transient postoperative functional inhibition of propulsive bowel activity, commonly occurs in patients after cardiac surgery and contributes to postoperative morbidity.
- Trial name
- TRANSIT (NCT04433390)
- Testing
- Naloxegol, inert tablet
- Where
- France
- Volunteers
- 305 people
- Sponsor
- CMC Ambroise Paré
Aortic Aneurysm and Dissection, Coronary Artery Disease (CAD)
Effects of Myofascial Release on Cardiac Patients After Median Sternotomy
After deciding to join this study and signing the informed consent form, participants will undergo the following interventions: All participants will receive a preoperative assessment (Tp) before surgery.
- Conditions
- Aortic Aneurysm and Dissection, Coronary Artery Disease (CAD), Valve Heart Disease
- Trial name
- NCT07649330
- Testing
- myofascial release+Routine Physical Therapy, Routine Physical therapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Siou-Pin Huang
Open Heart Surgery
Early Evaluation After Cardiac Surgery
The aim of this study is to examine the changes in respiratory function, respiratory muscle strength and functional capacity markers and the relationship between them in patients who have undergone open heart surgery and are at…
- Trial name
- NCT05932368
- Testing
- evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- University of Beykent
Left Atrial Appendage Thrombosis
The Left Atrial Appendage Closure by Surgery and the Incidence of Stroke in Patients Undergoing Open-heart Surgery.
This study aims to assess the efficacy and safety of prophylactic surgical closure of the left atrial appendage for stroke and cardiovascular death prevention in patients undergoing open heart surgery, regardless of their…
- Trial name
- NCT06172738
- Testing
- the left atrial appendage closure through surgery.
- Volunteers
- 100 people
- Sponsor
- Assiut University
Neonatal Patients Undergoing Major Non-cardiac Surgery, Congenital Anomaly
Neonatal Enhanced Recovery After Surgery (ERAS) Outcomes Study
The goal of this observational study is to improve the way newborn babies are cared for before, during, and after major surgery. Surgery can be very stressful on a baby's body.
- Trial name
- NEO (NCT07771478)
- Testing
- Pre-nERAS Guideline Implementation Intervention, Multifaceted Implementation of nERAS Guideline Intervention
- Where
- 3 sites in Canada, United Kingdom
- Volunteers
- 400 people
- Sponsor
- The Hospital for Sick Children
Hyperoxia, Cardiac Surgery
Oxygenation Targets in Cardiac Surgery Patients - a Before-and-after Study
During surgery high concentrations of supplementary oxygen are routinely administrated. However, there is increasing evidence of potential harm with liberal oxygen therapy.
- Conditions
- Hyperoxia, Cardiac Surgery, Cardiopulmonary Bypass, Acute Lung Injury
- Trial name
- NCT04133740
- Testing
- Oxygen
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Aalborg University Hospital
Surgical Site Infection After Major Surgery, Surgical Site Infections
Assessing the Effect of the Silver Dressing on Surgical Site Infections in Adult Patients Post Cardiac Surgery: a Single Center Randomized Control Trial
RCT on post-cardiac surgery patients using silver dressings vs. standard care. Conducted in ICU, CCU, telemetry units. Outcomes assessed via checklist \& modified Parsonnet Score.
- Trial name
- NCT07008040
- Testing
- Silver dressing
- Where
- Saudi Arabia
- Volunteers
- 145 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Congenital Heart Disease
Use of a Predictive Analytics Algorithm to Optimize Weaning of Inotropes Following Pediatric Cardiac Surgery
The objective of this study is to determine the effectiveness of a real time continuous risk analytics algorithm in the successful de-escalation of vasoactive and inotropic support in pediatric patients following cardiac surgery.
- Trial name
- NCT04600700
- Testing
- Clinical Decision support system (CDSS) for inotrope weaning
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston Children's Hospital
Coronary Artery Bypass, Off-Pump, Minimally Invasive Cardiac Surgery
MInithoraCotomy vs Sternotomy for Multivessel Coronary Artery Bypass Grafting: A Partially Randomized Patient Preference Trial Assessing Quality of Life and Patency Outcomes
This trial will address essential questions of the efficacy and safety of MICS-CABG in addition to the quality of life and patency rate of the grafts.
- Trial name
- NCT04795193
- Testing
- Minimal invasive coronary surgery, Off-pump coronary artery bypass surgery
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Peking University Third Hospital
Congenital Heart Disease
Ocular and Vision Problems in Patients After Fontan Operation
The purposes of this study are to identify indicators of vision problems and ocular abnormalities in patients with a Fontan circulation through a standardized questionnaire and to correlate the intraocular pressure measured with…
- Trial name
- NCT03170778
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Stanford University
Pulmonary Hypertension
Does Oral Sildenafil (Viagra) Decrease Mean Pulmonary Artery Pressure After Cardiac Surgery?
Post-operative pulmonary hypertension is a risk factor for right ventricular failure and an increasing cause of morbidity and mortality in patients undergoing high-risk cardiac surgery.
- Trial name
- NCT00334490
- Testing
- Sildenafil
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Unity Health Toronto
Acute Kidney Injury (AKI)
Acute Kidney Injury as a Risk Factor for Myocardial Injury After Non Cardiac Surgery
The incidence of acute kidney injury (AKI) postoperatively has been identified to be 21.6% in adults and 18.3% in hospitalized individuals.
- Trial name
- NCT05068167
- Testing
- Kidney function test
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- South Egypt Cancer Institute
Breathing Exercises, Cardiac Surgery
The Effect of Breathing Exercise Applied With Incentive Spirometer
It was conducted as a single-center, prospective, randomized controlled experimental study. Data were collected with the Introductory Information Form, Numerical Rating Scale, Physiological Parameters Follow-up Form and General…
- Conditions
- Breathing Exercises, Cardiac Surgery, Incentive Spirometry
- Trial name
- NCT06507163
- Testing
- The post-surgical breathing exercise group, The pre- and post- surgical breathing exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- TC Erciyes University
Cardiac Output
Total-body 13N-NH3 PET/CT to Study the Blood Perfusion in Severe AS Patients Pre- and Post-TAVR in Whole Body
The aim of our study is to analyze and quantitate whole-body blood perfusion by total-body 13N-NH3 PET/CT(uEXPLORER), and evaluate the influence to other organs in severe AS patients and the impact of TAVR surgery.
- Trial name
- NCT04941248
- Testing
- total-body PET/CT(uEXPLORER , United Imaging Healthcare, China)
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Thoracic Surgery
Positive Expiratory Pressure With Blow-bottle Device Versus EPAP After Postoperative Cardiac Surgery
Cardiac surgery is a recommended therapeutic option as a form of secondary prevention for the treatment of cardiovascular diseases, but may present postoperative alterations such as reduction of pulmonary volumes and flows…
- Trial name
- NCT03639974
- Testing
- PEP in a blow-bottle device, EPAP, conventional physiotherapy
- Where
- Brazil
- Volunteers
- 163 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Post Cardiac Surgery Systemic Inflammatory Response
Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery
Protocol Summary STUDY DESIGN A pilot, prospective, double blind, randomized, placebo controlled study. STUDY POPULATION Patients assigned to elective CABG with cardiopulmonary bypass (CPB) at the Department of Cardiothoracic…
- Trial name
- NCT02191839
- Testing
- Alpha 1-Antitrypsin
- Volunteers
- 20 people
- Sponsor
- Soroka University Medical Center