Clinical trials: Post-cardiac Surgery Patients
Coronary Artery Disease
GUARD-AKI: Validation of AKI-Sapere in Cardiac Surgery Patients
Cardiac surgery associated acute kidney injury (CSA-AKI) has been recognized as the second most common cause of hospital acquired AKI.
- Trial name
- NCT03635606
- Where
- 3 sites in United States
- Volunteers
- 370 people
- Sponsor
- Sapere Bio
Elective Cardiac Surgical Patients
Ventilatory Strategies After Cardiopulmonary Bypass Evaluated by Electrical Impedance Tomography
Pulmonary complications after cardiac surgeries are common. It is one of the most crucial concerns of cardiac surgeons and anesthesiologists.
- Trial name
- NCT04813250
- Testing
- ventilation mode setting
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Defense Medical Center, Taiwan
Myocardial Injury, Non-cardiac Surgery
The Effect of Remote Ischemic Preconditioning on Myocardial Injury After Noncardiac Surgery
This is a multicentre, parallel-group, randomised, sham-controlled, observer blinded trial, assessing the efficacy of remote ischemic preconditioning on preventing myocardial injury after noncardiac surgery.
- Conditions
- Myocardial Injury, Non-cardiac Surgery, Remote Ischemic Preconditioning
- Trial name
- NCT05733208
- Testing
- Remote ischemic preconditioning
- Where
- China
- Volunteers
- 766 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Major Abdominal Surgery
Preoperative Measurement of Heart Rate Variability as a Predictor of Postoperative Outcome
The purpose of the study is to confirm the hypothesis that a dysfunction of the autonomic nervous system could complicate the postoperative course in the patient undergoing surgery.
- Trial name
- NCT02375412
- Testing
- Pre-operative measurement of heart rate variability
- Where
- Czechia
- Volunteers
- 65 people
- Sponsor
- University Hospital Ostrava
Cardiac Complication
Fluid Responsiveness in Post Cardiac Surgery Patients
The aim of the study is to compare end expiratory occlusion test to passive leg raising test for prediction of fluid responsiveness in post cardiac surgery mechanically ventilated patients.
- Trial name
- Cardiac (NCT06583200)
- Testing
- End Expiratory Occlusion Test, Passive Leg Raising Test
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cardiac Complication, Postoperative Complications
Remote Electrocardiographic (ECG) ST-Monitoring (PROSE 3)in Post-op Patients
In moderate to high risk patients, cardiovascular complications after surgery account for almost 60% of death after surgery. This study will randomize 140 patients into routine postop care with Holter monitoring versus routine…
- Trial name
- PROSE 3 (NCT01423136)
- Testing
- Remote ECG monitoring Spacelab SL 1050
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- Ottawa Hospital Research Institute
Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery
ESPB vs SPSIP for Postoperative Analgesia After CABG
This prospective, randomized, active-controlled, double-blind, parallel-group study compares the postoperative analgesic efficacy and safety of ultrasound-guided bilateral Erector Spinae Plane Block (ESPB) versus bilateral…
- Conditions
- Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery, Postoperative Pain Management
- Trial name
- ESP-SPSIP-CABG (NCT07388745)
- Testing
- Ultrasound-guided Erector Spinae Plane Block (ESPB), Ultrasound-guided Serratus Posterior Superior Intercostal Plane Block (SPSIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Kutahya Health Sciences University
Cardiac Surgery, Inflammation
Impact of Ascorbic Acid on Post-Cardiothoracic Surgery Inflammation
The purpose of this study is to see if ascorbic acid (Vitamin-C) therapy will reduce inflammation following heart surgery.
- Trial name
- AFIST (NCT00519337)
- Testing
- Ascorbic acid
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Hartford Hospital
Coronary Heart Disease, Mindfulness
Mindfulness-based Interventions on Psychophysiological Recovery and Physical Functioning After Coronary Heart Surgery
The purpose of this study is to explore the effect of mindfulness on the physical and mental recovery and physical function of patients after coronary heart surgery.
- Conditions
- Coronary Heart Disease, Mindfulness, Recovery, Psychological, Physical Functioning
- Trial name
- NCT06637969
- Testing
- mindfulness-based
- Where
- Taiwan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Congenital Heart Defect
The Effects of Inhaled Nitric Oxide After Fontan Operation
Pleural effusions continue to be a post-operative complication seen after Fontan operation. This study will examine the use inhaled nitric oxide (iNO) given for 54 hours after Fontan operation to improve fluid balance.
- Trial name
- NCT00945529
- Testing
- inhaled nitric oxide (iNO)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Ellen Spurrier
Heart Disease, Aging
Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement.
Background: The prevalence of both senile cardiac amyloidosis (CA) and aortic stenosis (AS) markedly increases with age. Aortic stenosis increases left ventricular pressure overload.
- Conditions
- Heart Disease, Aging, Amyloidosis, Aortic Valve Stenosis
- Trial name
- AMYLOCARTESIAN (NCT02260466)
- Testing
- a basal LV septum biopsy
- Where
- 5 sites in France
- Volunteers
- 186 people
- Sponsor
- French Cardiology Society
Post Operative Pain, Bradycardia
Comparison of EOSP Between Usg Guided S-FICB vs USG Guided PENG Block in Pts Undergoing Femur Fracture Surgery
To compare the immediate and postoperative analgesic efficacy of S-FICB and PENG block will be the objective. The use of ultrasonography in anesthesia has helped the anesthetist to see the nerve, needle and the distribution of…
- Conditions
- Post Operative Pain, Bradycardia, Hypotension, Femur Fracture
- Trial name
- NCT06568770
- Testing
- USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK, PERICAPSULAR NERVE BLOCK
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Sahiwal medical college sahiwal
Coronary Artery Disease, Pain, Postoperative
Parasternal Nerve Block in Cardiac Patients
Exparel is a new local analgesic (numbing medication) that is intended to be longer acting than currently available local analgesics.
- Trial name
- NCT01826851
- Testing
- Exparel
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Peter A Knight
Cardiac Surgery, Cardiopulmonary Bypass
Low-dose Dexmedetomidine and Postoperative Delirium After Cardiac Surgery
Delirium is an acutely occurred and fluctuating cerebral dysfunction characterized with inattention, altered consciousness, cognitive decline and/or abnormal perception.
- Conditions
- Cardiac Surgery, Cardiopulmonary Bypass, Dexmedetomidine, Delirium
- Trial name
- NCT03624595
- Testing
- Dexmedetomidine
- Where
- 2 sites in China
- Volunteers
- 504 people
- Sponsor
- Dong-Xin Wang
Postoperative Complications, Surgical Wound Infection
Acupuncture and Post-Surgical Wound Healing
The purpose of this study is to determine if acupuncture improves wound healing. Since we, the investigators at the University of California, San Francisco (UCSF), know that how much oxygen is delivered to tissue is the best…
- Conditions
- Postoperative Complications, Surgical Wound Infection, Surgical Wound Dehiscence
- Trial name
- NCT00260494
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, San Francisco
Cardiac Surgery Requiring Cardiopulmonary Bypass
Vancomycin Concentration Analysis in Post-Cardiac Surgery Patients
The benefits of antimicrobial prophylaxis for cardiac surgery have been clearly demonstrated in placebo-controlled studies. Prophylactic intravenous antibiotics are therefore administered, with agent selection directed against…
- Trial name
- NCT07087301
- Testing
- subtherapeutic concentration risk group
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Pengqiang Du
Post Operative Atrial Fibrillation
The Impact of Oral Vitamin C in Prevention for Post Operative Atrial Fibrillation (POAF) in Coronary Artery Bypass Surgery (CABG) Patients
Post operative atrial fibrillation (POAF) is one of the most common complications that takes place worldwide after coronary artery bypass surgeries (CABG).
- Trial name
- NCT06074367
- Testing
- Vitamin C 500 MG Oral Capsule(High dose 2g daily), Vitamin C 500 MG Oral Capsule(Low-dose 1g daily)
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Helwan University
Focus of Study, Coagulation Status of Cardiac Surgery Patient
Thromboelastography-derived Functional Fibrinogen Levels
This study hopes to determine if thromboelastography-derived functional fibrinogen (TEG-FF or FLEV) levels obtained during the rewarming phase of cardiopulmonary bypass can provide information on coagulation status sooner…
- Conditions
- Focus of Study, Coagulation Status of Cardiac Surgery Patient, Reducing Excess Blood Transfusion
- Trial name
- TEG-FF (NCT01992757)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Pennsylvania
Acute Kidney Injury
Study to Prevent Acute Kidney Injury After Cardiac Surgery Involving Cardiopulmonary Bypass
The objective of the study is to assess the safety and efficacy of ANG-3777 in preventing AKI compared to placebo when administered to patients at risk for developing acute kidney injury (AKI) following cardiac surgical…
- Trial name
- NCT02771509
- Testing
- ANG-3777
- Where
- 40 sites in United States, Brazil and 2 more
- Volunteers
- 275 people
- Sponsor
- Angion Biomedica Corp
Respiratory Acidosis in ICU Patients, Right Ventricular (RV) Dysfunction
Right Ventricular Function and Respiratory Acidosis After Cardiac Surgery
Right heart dysfunction remains a frequent cause of morbidity and mortality after cardiac surgery. Respiratory acidosis, particularly when accompanied by hypoxemia, plays a significant role in right heart failure, primarily by…
- Conditions
- Respiratory Acidosis in ICU Patients, Right Ventricular (RV) Dysfunction, Hemodynamic Changes, Mechanical Ventilation
- Trial name
- NCT07619274
- Testing
- Not applicable- observational study
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Laval University