Clinical trials: Post-cardiac Surgery Patients
Coronary Artery Disease
Home-Based Versus Center-Based Cardiac Rehabilitation After CABG Surgery
This randomized controlled trial was designed to compare the efficacy of a 12-week home-based telerehabilitation (HBTCR) program against traditional center-based cardiac rehabilitation (CBCR) and usual care in patients who have…
- Trial name
- NCT07243444
- Testing
- Structured Exercise Program, Standard Health Education
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The First Hospital of Hebei Medical University
Coronary Bypass Graft Stenosis, Valvular Heart Disease
Comparison of Post-operation Cardiopulmonary Capacity of Patients Underwent Conventional and Robot-assisted Coronary Artery Bypass Graft and Valve Replacement Surgery
Robotic surgery is one of the most popular minimally invasive procedures for patients with coronary artery disease or valvular diseases.
- Trial name
- NCT05430568
- Testing
- robot-assisted surgery
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taichung Veterans General Hospital
Stress Hyperglycemia
Metabolic Phenotyping During Stress Hyperglycemia in Cardiac Surgery Patients
This study is a prospective randomized study to examine the effects of exposure to dulaglutide on the prevention of stress-hyperglycemia and the metabolic inflammatory response in the perioperative period.
- Trial name
- NCT03743025
- Testing
- Dulaglutide Injection, Saline Injection
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- Emory University
Cardiac Toxicity, Sarcoma
Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy before surgery may shrink the tumor so that it can be removed during surgery.
- Trial name
- NCT00019864
- Testing
- filgrastim, cisplatin, dexrazoxane hydrochloride
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Cancer Institute (NCI)
Delirium
Incidence, Severity and Treatment of Delirium in Cardiac Surgery Patients: A Before-after Study
Delirium is a common yet under diagnosed condition in hospitalized patients, and the incidence have not previously been described in Danish cardiac surgery patients.
- Trial name
- NCT01774240
- Testing
- systematic screening and treatment of delirium
- Where
- Denmark
- Volunteers
- 230 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Artery Disease
Impact of Three Body Positioning Strategies in the Drainage Fluids After Coronary Artery Bypass Surgery
To investigate different strategies of body positioning associated to early corporal mobilization and verify the impact int the time and quantification of thoracic and mediastinal drainage, pulmonary complications and time of…
- Trial name
- positioning (NCT02525289)
- Testing
- Bed Rotation Group, Orthostatic Group
- Volunteers
- 101 people
- Sponsor
- University of Sao Paulo General Hospital
Patients Waiting for Coronary Artery Bypass Graft Surgery, Patients Waiting for Aortic Valve Repair or Replacement
Pre-operative Rehabilitation for Reduction of Hospitalization After Coronary Bypass and Valvular Surgery.
The PREHAB study is a clinical trial where frail patients waiting for heart surgery are randomly chosen to either receive the current standard of care or to participate in an 8-week exercise/education program at a community-based…
- Conditions
- Patients Waiting for Coronary Artery Bypass Graft Surgery, Patients Waiting for Aortic Valve Repair or Replacement, Patients Waiting for Mitral Valve Repair or Replacement, Patients Waiting for Combined Procedures. (CAGB and Valve)
- Trial name
- PREHAB (NCT02219815)
- Testing
- Prehab Intervention
- Where
- 5 sites in Canada
- Volunteers
- 89 people
- Sponsor
- St. Boniface Hospital
Periodontitis, Chronic Periodontitis (Disorder)
Cofilin-2 (rs80358250) and Lactoferrin (rs1126478) Polymorphism and Protein Levels With Non Surgical Periodontal Therapy in Periodontitis Patients With and Without CHD
Periodontitis is a chronic multifactorial inflammatory disease associated with the accumulation of dental plaque and characterized by progressive destruction of the teeth-supporting apparatus, including the periodontal ligament…
- Conditions
- Periodontitis, Chronic Periodontitis (Disorder), Coronary Heart Disease
- Trial name
- NCT07353606
- Testing
- Scaling and root planing
- Where
- 2 sites in India
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Postoperative Complications
Cardiopulmonary Exercise Testing in Cardiosurgery Patients
Cardiopulmonary exercise testing (CPET) is considered to be a gold standard in pre-operative risk assessment and stratification of high risk patients scheduled for major surgery.
- Trial name
- NCT06702059
- Testing
- Cardiopulmonary exercise testing
- Where
- 2 sites in Czechia
- Volunteers
- 130 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Cardiac Surgery Patient, Postoperative Pain
Effect of Intraoperative Morphine on Postoperative Pain After CABG
Ethics committee approval was obtained for this study, which was planned as a prospective, randomized, controlled, single-center trial to be conducted in patients undergoing coronary artery bypass grafting (CABG) surgery between…
- Conditions
- Cardiac Surgery Patient, Postoperative Pain, Pain After Surgery
- Trial name
- NCT07472959
- Testing
- In this study, morphine administration, which is routinely and frequently used in our operating room for patients undergoing CABG, was applied as an additional intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Atrial Fibrillation, Acute Kidney Injury
Autonomic State, Cardiovascular Control and Outcomes in Coronary Surgery
Characterization of the perioperative autonomic nervous system state, cardiovascular and cerebrovascular control and microcirculation in order to predict postoperative atrial fibrillation and acute kidney injury in patients…
- Trial name
- NCT03169608
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Policlinico S. Donato
Post-cardiac Surgery
Group-based Cardiac Rehabilitation on Patients With Coronary Artery Bypass Graft Surgery
1. To determine the effect of Moderate intensity continuous training on Pulmonary function of CABG patients. 2. To determine the effect of MICT on aerobic Capacity of CABG patients.
- Trial name
- NCT06317376
- Testing
- MICT with Aerobic exercise on treadmill, standard hospital protocol
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Acute Kidney Injury, Cardiac Surgery
Fluid-removal Guided by VeXUS Score With Usual Care in Patients With Acute Kidney Injury After Cardiac Surgery
Acute kidney injury affects more than 30% of patients after cardiac surgery, and is associated with an excess in mortality. There is a clinical continuum between acute kidney injury (transient if <48h, persistent if >48h), the…
- Conditions
- Acute Kidney Injury, Cardiac Surgery, Venous Congestion, Hemodynamic Stability
- Trial name
- VeXUS (NCT06251713)
- Testing
- VeXUS score guided fluid management strategy, Usual care
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Cardiovascular Diseases, Coronary Artery Disease
Depressive Symptoms After Cardiac Surgery
The primary goal of this project is to develop a predictive model for clinically significant depressive symptoms (CSDS) in patients undergoing coronary artery bypass graft (CABG) surgery, using pre- and perioperative data.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Depression
- Trial name
- PCD (NCT06706323)
- Where
- 2 sites in Switzerland
- Volunteers
- 300 people
- Sponsor
- Roland von Känel
Respiratory Insufficiency, ARDS
Feasibility and Efficacy of Automated Lateral Decubitus Therapy in Hypoxemic Respiratory Failure
The mortality of patients with acute respiratory distress syndrome (ARDS) remains high despite recent advances in lung-protective strategies and even after the overall improvement in intensive care (management of sepsis…
- Conditions
- Respiratory Insufficiency, ARDS, Post Cardiac Surgery Patients, Hypoxemic Respiratory Failure
- Trial name
- NCT06698913
- Testing
- Rotational Therapy
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Sao Paulo General Hospital
Coronary Artery Bypass Graft Surgery, Mace
Discharge Planning Program for Post CABG Patients
The current study is utilizing a nurse led discharge program based on the Re-Engineered Discharge program (Project-RED) ( Agency of Healthcare Research and Quality [AHRQ], 2013) which is a package of services designed to minimize…
- Conditions
- Coronary Artery Bypass Graft Surgery, Mace, 30 Day Mortality
- Trial name
- NCT04527822
- Testing
- Nurse led discharge planning program
- Where
- Jordan
- Volunteers
- 174 people
- Sponsor
- University of Jordan
Disruption or Dehiscence of Closure of Sternum or Sternotomy
Treatment With PTH After Sternotomy in Cardiac Surgery Patients
The aims of this study is to compare healing time and quality of newly formed bone in cardiac surgery patients treated with PTH post-surgically and a control group treated with saline.
- Trial name
- PAATH (NCT01466829)
- Testing
- Parathyroid hormone
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Post Induction Hypotension
Comparing the Hemodynamic Effects of Volume Loading vs Non-loading During Induction of Anesthesia in Fluid Responder Patients With Coronary Artery Disease Undergoing Elective Coronary Artery Bypass Graft Surgery: a Randomized Controlled Study.
All preoperative cardiac medications will be continued till the morning of the surgery, except angiotensin converting enzyme inhibitors.
- Trial name
- NCT05462847
- Testing
- Ringer acetate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Cardiac Surgery
Optimal Timing of Coronary Artery Bypass Grafting in Hemodynamically Stable Patient After Myocardial Infarction and Definition of Poor Prognostic Factors. Pilot Study
Acute coronary syndromes (ACS) represent the leading cause of death in France. Their incidence is increasing due to population aging and to the persistence of cardiovascular risk factors.
- Trial name
- NCT03863158
- Testing
- No intervention
- Volunteers
- 476 people
- Sponsor
- Centre Hospitalier La Chartreuse
Elderly Patients, Non-cardiac Surgery
Effects of Limb Remote Ischemic Preconditioning for Prevention of Delirium in Elderly Patients After Non-cardiac Surgery
To investigate whether limb remote ischemic preconditioning (LRIP) could safely decrease the incidence of delirium in elderly patients after non-cardiac surgery.
- Trial name
- LRIP-D (NCT03028389)
- Testing
- limb remote ischemic preconditioning(LRIP)
- Volunteers
- 611 people
- Sponsor
- Nanfang Hospital, Southern Medical University