Clinical trials: Post-cardiac Surgery Patients
Coronary Disease
Circulatory Oscillations in Post Cardiac Surgery Patients
In this observational study investigators examine the presence of circulatory oscillations in blood pressure, heart rate, and doppler laser flow before and after planned cardiac surgery.
- Trial name
- NCT02765607
- Testing
- Heart surgery
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- St. Olavs Hospital
Perioperative Myocardial Injury
Incidence and Outcome of Perioperative Myocardial Injury After Non-cardiac Surgery
This observational study includes patients undergoing major non-cardiac surgery, and screens them for the occurrence of perioperative myocardial injuries (PMI).
- Trial name
- BASEL-PMI (NCT02573532)
- Where
- Switzerland
- Volunteers
- 19,645 people
- Sponsor
- University Hospital, Basel, Switzerland
Lung Cancer, Atrial Fibrillation
PREvention of Atrial Fibrillation in patientS Undergoing thorAcic surGEry for Lung Cancer
The aim of this study is to assess whether prophylactic treatment with metoprolol or losartan is able to reduce the incidence of atrial fibrillation (AF) in patients undergoing thoracic surgery for lung cancer, showing elevated…
- Trial name
- PRESAGE (NCT01281787)
- Testing
- Metoprolol, Losartan
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- European Institute of Oncology
Congenital Heart Disease
Use of a Predictive Analytics Algorithm to Optimize Weaning of Inotropes Following Pediatric Cardiac Surgery
The objective of this study is to determine the effectiveness of a real time continuous risk analytics algorithm in the successful de-escalation of vasoactive and inotropic support in pediatric patients following cardiac surgery.
- Trial name
- NCT04600700
- Testing
- Clinical Decision support system (CDSS) for inotrope weaning
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston Children's Hospital
Pain, Acute, Pain, Chronic
Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical Patients
This study is a single-center, phase II, randomized, placebo-controlled, Bayesian-designed, double-blinded trial Goal and Questions: The primary goal is to evaluate if a combination of taurine and butyrate can reduce chronic…
- Conditions
- Pain, Acute, Pain, Chronic, Chronic Post Operative Pain
- Trial name
- NCT07144033
- Testing
- Butyrate and Taurine
- Where
- Hong Kong
- Volunteers
- 216 people
- Sponsor
- Chinese University of Hong Kong
Post-operative Cognitive Dysfunction
Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly
BACKGROUND: Post-operative cognitive dysfunction (POCD) is a potentially irreversible loss of brain functions observed in elderly patients after surgical operations under general anaesthesia.
- Trial name
- THE BRIDGE (NCT02428062)
- Testing
- Hemodynamic target, Phenylephrine, Intravenous fluids
- Where
- Italy
- Volunteers
- 1,812 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Myocardial Infarction
the Effect of Danhong Injection on Microcirculation in the Treatment of Patients With STEMI After the PTCA Surgery.
This study focused on the effect of Danhong injection on microcirculation in the treatment of patients with STEMI(ST-elevation myocardical infarction) after the PTCA surgery.
- Trial name
- Danhong (NCT02158559)
- Testing
- Danhong Injection, Normal Saline
- Volunteers
- 180 people
- Sponsor
- Beijing Bozhiyin T&S Co., Ltd.
Postoperative Vasoplegic Syndrome
Small Doses of Pituitrin Versus Norepinephrine for the Management of Vasoplegic Syndrome in Patients After Cardiac Surgery
Vasoplegic syndrome is a common complication after cardiac surgery. Low dose vasopressin can up-regulate blood pressure and improve clinical outcomes compared with norepinephrine (mainly acute kidney injury Anesthesiology 2017…
- Trial name
- NCT03106831
- Testing
- Pituitrin infusion, Norepinephrine infusion
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Bypass Surgery
Study of Role of Blood Microvescicles and Exosomes in Patients With Graft Occlusion After Aortocoronary Bypass Surgery
Coronary artery bypass graft (CABG) surgery is still the standard treatment of coronary revascularization for patients with severe coronary artery disease (CAD).
- Trial name
- MVBYPASS (NCT05411445)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Maria Cecilia Hospital
Post Operative Arrythmia
Impact of Ligament of Marshall Resection on Atrial Fibrillation Occurrence in Patients Undergoing Coronary Artery Bypass Grafting: A Randomized Controlled Trial
Background: 20-40% of patients with ischemic heart disease managed with coronary artery bypass grafting (CABG) surgeries face the risk of postoperative atrial fibrillation (POAF), which is a known hazardous outcome.
- Trial name
- NCT07492901
- Testing
- A standard on-pump coronary artery bypass grafting (ON-CAB), adjunctive LoM resection
- Where
- 2 sites in Egypt
- Volunteers
- 220 people
- Sponsor
- Kasr El Aini Hospital
Heart; Surgery, Heart, Functional Disturbance as Result
FAPO-X: Assisted Digital Telemonitoring With Wearables in Patients After Cardiovascular Surgery
This study aims to develop a digitally assisted telemonitoring platform using the Samsung TM Galaxy Watch5 smartwatch, validating the applicability of the solution in patients with POAF (Postoperative Atrial Fibrillation), along…
- Trial name
- FAPO-X (NCT05966857)
- Testing
- Wearable: Smartwatch
- Where
- Brazil
- Volunteers
- 108 people
- Sponsor
- University of Sao Paulo
Hypoxia
Trans Alveolar Pressure Measurement as an Index for Lung Recruitment.
the study is conducted on hypoxic adult patients underwent open heart surgery after arrival to the intensive care unit and stabilization of patients' hemodynamics to assess the efficacy of transalveolar pressure measurement as an…
- Trial name
- NCT04168151
- Testing
- lung recruitment protocol
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- University of Alexandria
Aortic Valve Disease
Health Status of < 50 Year Old Patients After Surgically Implanted Biological and Mechanical Aortic Valves: a Population-based Retrospective Analysis (2010-2020)
The overall project aim is to study outcomes following aortic valve replacement with either mechanical valves or bioprostheses by retrieving data from the main social security carriers in Austria for the years 2010-2020 in under…
- Trial name
- NCT05627973
- Testing
- Aortic Valve Replacement
- Volunteers
- 991 people
- Sponsor
- Medical University of Vienna
Valve Heart Disease, Coronary Artery Disease
Post-Operative Myocardial Incident & Atrial Fibrillation
To explore predictors of major cardio-vascular events after cardiac surgery and trans-catheter valve implantation with a specific interest in studying mechanisms linking pre-operative leukocyte, fat and myocardial phenotypes with…
- Trial name
- POMI-AF (NCT03376165)
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Lille
Type 2 Diabetes Mellitus, Obesity
Macrovascular and Microvascular Morbidity and Mortality After Metabolic Surgery Versus Medicines
The goal of this study is to compare the impact of metabolic surgery and a class of anti-diabetes medications (Glucagon-like peptide-1 receptor agonists,GLP-1 RAs) on occurrence of diseases involving small and large vessels such…
- Conditions
- Type 2 Diabetes Mellitus, Obesity, Microvascular Disease, Macrovascular Disease
- Trial name
- M6 (NCT06355219)
- Volunteers
- 3,932 people
- Sponsor
- Ali Aminian
Sleep
Standardized Sleep Bundle for Cardiac Surgery Patients
The goal of this clinical trial is to evaluate the feasibility of using a standardized sleep bundle in adults undergoing cardiac surgery. The main questions it aims to answer are: 1.
- Trial name
- NCT07401836
- Testing
- Standardized Sleep Protocol, Usual Post Operative Care
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Horizon Health Network
Atrial Fibrillation
Effect of Venous Cannulation on the Incidence of Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass
Context Atrial fibrillation is the most frequent arrhythmia following coronary artery bypass grafting. POAF is associated with worse outcomes following CABG.
- Trial name
- NCT04641611
- Testing
- Bicaval cannulation, Cavoatrial cannulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Dr. Jean-Francois Morin
Congenital Heart Disease
Relationship of Brain Natriuretic Peptide (BNP) Levels to Cardiac Diagnosis, Operation Performed, Post-operative Course and Outcome
The purpose of this study is to assess brain natriuretic peptide levels to evaluate the relationship of those levels with the diagnosis of congenital cardiac disease, operation performed, post-operative course, and outcome.
- Trial name
- NCT00238810
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Healthcare of Atlanta
Coronary Artery Disease
Using WHOOP Fitness Band to Measure Heart Health Variability Before and After Surgery
The goal of this observational study is to use the WHOOP device to measure heart rate variability (HRV) in patients with coronary artery disease (CAD) before and after they have CABG (coronary artery bypass graft) surgery.
- Trial name
- NCT07097168
- Where
- United States
- Sponsor
- Tufts Medical Center
Physical Therapy in Cardiac Surgery Patients
Impact of Physiotherapy Session in Cardiac Surgery Patients
This work consists, first of all, in making an inventory of the physiotherapy of the patient undergoing cardiac surgery under high flow oxygenation at the CHRU NANCY.
- Trial name
- NCT04793802
- Testing
- PHYSIO
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Central Hospital, Nancy, France