Clinical trials: Post-menopausal
Urinary Incontinence
Comparison Between Pelvic Muscle Training and Pilates Exercises for UI in Postmenopausal Women
Introduction: Urinary incontinence (UI) is a condition that affects around 40% of postmenopausal women and is therefore considered a public health problem.
- Trial name
- NCT05446792
- Testing
- PFMT, PE
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Norte do Parana
Neoplasms, Breast Neoplasms
Study of Anastrozole +/- AZD8931 in Postmenopausal Women With Endocrine Therapy Naive Breast Cancer
The main purpose of this study is to compare progression free survival in patients treated with AZD8931 given in combination with anastrozole versus anastrozole alone.
- Conditions
- Neoplasms, Breast Neoplasms, Breast Cancer
- Trial name
- MINT (NCT01151215)
- Testing
- AZD8931, anastrozole
- Where
- 60 sites in United States, Brazil and 16 more
- Volunteers
- 482 people
- Sponsor
- AstraZeneca
Breast Cancer
PROACT - Pre-Operative Arimidex Compared To Tamoxifen
The purpose of this study is to compare tamoxifen, versus a newer treatment, ARIMIDEX, which we already know to be well tolerated.
- Trial name
- NCT00232661
- Testing
- ARIMIDEX (anastrazole), NOLVADEX (tamoxifen)
- Where
- 79 sites in United States, Belgium and 8 more
- Volunteers
- 452 people
- Sponsor
- AstraZeneca
Frozen Shoulder, Adhesive Capsulitis
Effect of Hormone Replacement Therapy on Physiotherapy Outcomes in Postmenopausal Women With Frozen Shoulder
The purpose of this study is to compare the effects of a physiotherapy program on pain levels, shoulder range of motion, functional status, pain catastrophizing, perceived change, sleep quality, and quality of life in…
- Conditions
- Frozen Shoulder, Adhesive Capsulitis, Adhesive Capsulitis of the Shoulder, Hormone Replacement Therapy, Post-Menopausal
- Trial name
- NCT07736027
- Testing
- Standardized Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University - Cerrahpasa
Hair Thinning
Efficacy and Safety of a Nutraceutical Supplement With Standardized Botanicals in Peri-menopausal and Menopausal Women With Thinning Hair
NUTRAFOL® Women's Balance supplement is a novel nutraceutical supplement, scientifically formulated to specifically target the multiple underlying causes of hair loss and thinning in women.
- Trial name
- NCT04048031
- Testing
- Nutrafol Supplement Capsules
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ablon Skin Institute Research Center
to Assess Changes in Body Composition After Dietary Supplementation With Sinetrol
A Randomized, Double-blind, Placebo-controlled, Parallel Study to Assess the Effect of Sinetrol on Body Composition &Metabolic Health in Peri-menopausal/Early Menopausal Women
The menopausal transition is associated with significant hormonal and metabolic changes, primarily driven by a decline in estrogen levels.
- Trial name
- MENOFIT (NCT07782853)
- Testing
- dietary supplementation
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- DR Healthcare - biotexia
Osteoporosis
Role of Oxytocin in Post-menopausal Osteoporosis: Evaluation on the Population of the OPUS Cohort
Oxytocin is a neurohypophysial hormone involved in several central and peripheral functions including parturition, milk let-down reflex and social behaviour.
- Trial name
- NCT01192893
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Sleep Disturbance
A Study of a Sleep Supplement to Improve Sleep in Women Going Through Menopause
This study evaluated whether a daily dietary sleep supplement could improve sleep in women aged 40 to 65 who experience moderate sleep disturbances during menopause.
- Trial name
- NCT07375095
- Testing
- Sleep Supplement
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Bonafide Health
Sleep Problem
Effects of Internet - Based Cognitive Behavioral Therapy on Sleep Problems Among Sample of Post- Menopausal
Sleep problems become more prominent with aging and worse among post-menopause than perimenopause stage. The actual causes of sleep problems are unclear.
- Trial name
- NCT04719598
- Testing
- congnitive behavioural therapy
- Volunteers
- 80 people
- Sponsor
- Jouf University
Overactive Bladder (OAB), Menopause
Effect of Vaginal Estrogen on Alterations in the Urine Microbiome of Menopausal Women With Overactive Bladder
The goal of this Pre-Post Quasi-experimental study is to investigates the effect of vaginal estrogen therapy on changes in the urinary microbiome and its association with improvement in overactive bladder (OAB) symptoms in…
- Conditions
- Overactive Bladder (OAB), Menopause, Microbiome
- Trial name
- NCT06780163
- Testing
- 17β-estradiol 10 mcg
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Diabetes Mellitus, Quality of Life
Quality of Life in Pancreas Transplantation
Quality of Life for individuals with Insulin Dependent Diabetes Mellitus (IDDM) can be severely impaired by acute and chronic complications of the disease.
- Trial name
- NCT03921593
- Testing
- Solid Organ Pancreas Transplantation with or without Kidney Transplantation
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- University of Oxford
Breast Cancer
A Study of LY3484356 in Women With Breast Cancer Before Having Surgery
The purpose for this study is to see if the study drug, LY3484356, is safe and to determine what effects it has on breast cancer in participants with Estrogen Receptor Positive (ER+), HER2 Negative (HER2-) early stage (stage…
- Trial name
- EMBER-2 (NCT04647487)
- Testing
- LY3484356
- Where
- 19 sites in United States, Belgium and 4 more
- Volunteers
- 87 people
- Sponsor
- Eli Lilly and Company
Cardiovascular Disease, Diabetes
The FLAVO Trial: Dietary Flavonoids and Cardiovascular Disease Risk Reduction in Postmenopausal Women With Type 2 Diabetes
The purpose of this placebo controlled trial is to determine whether a year long intervention with flavonoids (found in cocoa and soy) is more effective in reducing the risk of cardiovascular disease in postmenopausal women with…
- Trial name
- FLAVO (NCT00677599)
- Testing
- Flavonoid enrichment (cocoa / soy compounds)
- Where
- United Kingdom
- Volunteers
- 152 people
- Sponsor
- University of East Anglia
Vulvovaginal Atrophy
Efficacy and Safety of HYDEAL-D Vaginal Pessaries Application on the Treatment of Vaginal Atrophy in Post-menopause Women
This study evaluates the efficacy and safety of hyaluronic acid derivative based vaginal pessaries for the treatment of symptoms of vulvo-vaginal atrophy in post-menopausal women.
- Trial name
- NCT03557398
- Testing
- Hydeal-D vaginal pessaries
- Where
- 2 sites in Slovakia
- Volunteers
- 40 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Sexual Dysfunction, Physiological
Vaginal Heat Wash-out (HWO) in 4 Groups of Women (Pre- and Postmenopausal With and Without Female Sexual Arousal Disorder (FSAD)).
The Pfizer developed Heat Wash-Out (HWO) system is a software controlled electromechanical system designed to measure vaginal wall blood flow. A small vaginal probe is attached to a control unit.
- Trial name
- FSAD HWO VBF (NCT00443248)
- Testing
- Vaginal Heat Wash-Out Device
- Where
- 2 sites in Australia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Pfizer
Hypertension (HTN)
NR and Exercise for Blood Pressure
Hypertension continues to pose a significant global health challenge, with rates of optimal blood pressure control remaining low - particularly in China, where fewer than 5% of individuals with hypertension achieve…
- Trial name
- NCT07475208
- Testing
- Brisk walking, Nicotinamide Riboside 1000 mg
- Volunteers
- 112 people
- Sponsor
- ZHANG Jiaqi
Breast Cancer
Letrozole in Treating Postmenopausal Women With Stage I, II or III Breast Cancer That Can Be Removed by Surgery
RATIONALE: Hormone therapy using letrozole may fight breast cancer by lowering the amount of estrogen the body makes. Giving letrozole before surgery allows us to monitor the effects of letrozole on the tumor on a molecular level…
- Trial name
- NCT00651976
- Testing
- letrozole, Blood Collection, biopsy/lumpectomy/mastectomy
- Where
- 5 sites in United States
- Volunteers
- 213 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Breast Neoplasms
Exemestane As Treatment In Adjuvant For Post-Menopausal Patients With Non-Metastatic Breast Cancer
To compare recurrence free survival between two treatment groups (5 years with exemestane vs 2.5 to 3 years tamoxifen followed by 2 to 2.5 years of exemestane for a total duration of 5 years) This Pfizer sponsored trial is part…
- Trial name
- TEAM (NCT00279448)
- Testing
- exemestane, tamoxifen
- Where
- 59 sites in France
- Volunteers
- 9,779 people
- Sponsor
- Pfizer
CVD Risk
Elucidating the Effect of Dietary Stearic Acid on the Regional Heterogeneity of the Gut Microbiome and Metabolome: Focus on Bile Acid Metabolism (SAMPill Study)
Stearic acid and palmitic acid are two common consumed saturated fatty acids found in foods. Palmitic acid is associated with increases in blood cholesterol, whereas stearic acid is generally considered neutral with respect to…
- Trial name
- SAMPill (NCT07766915)
- Testing
- High Palmitic Acid Diet, High Stearic Acid Diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Tufts University
Metastatic Breast Cancer
Study of Fulvestrant +/- Everolimus in Post-Menopausal, Hormone-Receptor + Metastatic Breast Ca Resistant to AI
Post-menopausal women with hormone-receptor positive (HR+) metastatic breast cancer resistant to aromatase inhibitor (AI) therapy will be randomized to receive Fulvestrant (Faslodex) with Everolimus or Fulvestrant (Faslodex) with…
- Trial name
- PrE0102 (NCT01797120)
- Testing
- Fulvestrant, Everolimus
- Where
- 25 sites in United States
- Volunteers
- 131 people
- Sponsor
- PrECOG, LLC.