Clinical trials: Post-operative
Delirium, Dementia, Amnestic, Cognitive Disorders, Postoperative Cognitive Dysfunction
n-3 Enriched Nutrition Therapy and Postoperative Cognitive Dysfunction After Cardiac Surgery
Background: Delirium and long-term cognitive dysfunction (CD) are important complications of major surgery and intensive care treatment.
- Trial name
- NCT00757913
- Testing
- n-3 enriched nutrition
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Basel, Switzerland
Out-Of-Hospital Cardiac Arrest, Post-Cardiac Arrest Syndrome
The Danish Out-of-Hospital Cardiac Arrest Study
After resuscitation from Out-of-Hospital Cardiac Arrest (OHCA) patients experience Post Cardiac Arrest Syndrome due to ischemia and reperfusion injury.
- Trial name
- DANOHCA (NCT05895838)
- Testing
- Dexamethasone, Backrest elevation, Early wakeup call
- Where
- 5 sites in Denmark
- Volunteers
- 1,000 people
- Sponsor
- Christian Hassager
Pain, Pain, Postoperative
Cryoablation of Intercostal Nerves for Post-Operative Pain Management in Opioid-Tolerant Patients
The main objective study is to compare the use of the cryoSPHERE probe to the standard-of-care method for pain management of patients receiving robotic-assisted thoracoscopic surgery, including reductions in opioid pain…
- Trial name
- NCT05276258
- Testing
- cryoSPHERE Ablation, Bupivacaine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- The Methodist Hospital Research Institute
Glaucoma, Inflammatory Response
Impact Post-operative Treatment on Intraocular Pressure Post-SLT on Patients With Primary Open-angle Glaucoma
The present study's main objective is to assess if there is a significant difference between either of the treatments frequently used in post-op, namely a topic cortisone-based treatment, an non-steroidal anti-inflammatory drug…
- Trial name
- SLT (NCT01058278)
- Testing
- Selective Laser trabeculoplasty
- Where
- Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Pneumothorax
Effect of Dissecting of The Inferior Pulmonary Ligament on Postoperative Pulmonary Reexpansion and Recurrence
This subject analysis of the influence of the dissociating inferior pulmonary ligament on pulmonary reexpansion and recurrence in the treatment of primary spontaneous pneumothorax by video assisted thoracic surgery.
- Trial name
- NCT02558608
- Testing
- DIPL, WR, thoracoscopic surgery
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Chinese Medical Association
Surgery Complications, Surgery
SurgWeek-2: Identifying the Global Burden of Post Operative Complications: an International Prospective Cohort Study Protocol
This study aims to assess and improve the global outcomes following surgery. Every year approximately 313 million operations are performed, with 50 million people experiencing a complication and unfortunately 3.5 million people…
- Conditions
- Surgery Complications, Surgery, Global Surgery, Robotic
- Trial name
- SurgWeek-2 (NCT07785076)
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Postoperative Pain
Postoperative Pain After a Laparoscopic Cholecystectomy
Randomized Controlled Trial to compare the effect of low (8 mmHg) versus Standard (14 mmHg) insufflation pressure of CO2 pneumoperitoneum on postoperative pain in patients undergoing laparoscopic cholecystectomy
- Trial name
- CPOP (NCT06685250)
- Testing
- Laparoscopic cholecystectomy
- Volunteers
- 190 people
- Sponsor
- Hopital Charles Nicolle
Cesarean Delivery; Neuraxial Opioids
Respiratory Rate After Cesarean Delivery
The study proposal summarizes aspects related to respiratory rate in women who undergo spinal anesthesia for cesarean delivery who receive or do not receive neuraxial opioids
- Trial name
- NCT04250233
- Testing
- Respiratory Monitor
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Breast Cancer, Postoperative Pain
Serratus Plane Block vs Erector Spinae Plane Block on Postoperative Analgesia in Patients Undergoing Unilateral Breast Surgery
Interfacial plan blocks are becoming more widely used for postoperative analgesia because of their easier applicability and less risk of complications.
- Trial name
- NCT04218149
- Testing
- Bupivacaine Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Orofacial Clefts, Cleft Lip and Palate
Analgosedation With Ketamine, Nalbuphine, or Dexmedetomidine for Suture Removal in Children After Cleft Surgery
This prospective, randomized study is designed to compare the efficacy and safety of three sedative-analgesic agents-intramuscular ketamine, intranasal nalbuphine, and intranasal dexmedetomidine-for procedural sedation in…
- Conditions
- Orofacial Clefts, Cleft Lip and Palate, Alveolar Ridge Defect
- Trial name
- KID-CLEFT (NCT07340008)
- Testing
- ketamine, Nalbuphine, Dexmedetomidine
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Postoperative Delirium, Hip Fractures
The Southeast and East Asian Post-Operative Delirium (SEAPOD) Study
The specific aim of the study will be to investigate the incidences and risk factors for postoperative delirium (POD) after hip fracture surgery in elderly patients aged ≥ 65 years in five different Southeast and East Asian…
- Trial name
- NCT04999891
- Testing
- Neurocognitive tests
- Where
- 13 sites in Japan, Malaysia and 3 more
- Volunteers
- 1,000 people
- Sponsor
- National University Hospital, Singapore
Postoperative Pain
Dexmedetomidine Versus Magnesium Sulfate Infusion During Spinal Anesthesia
The aim of this work is to compare the hemodynamic and analgesic properties of Dexmedetomidine and Magnesium sulphate infusion in lower abdominal surgery.
- Trial name
- NCT03640390
- Testing
- Dexmedetomidine, Magnesium Sulphate, Normal saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Crohn Disease
Comparison Azathioprine to Mesalazine for the Prevention of Postoperative Recurrence in the Crohn Disease
To show the superiority of Azathioprine comparing Mesalazine in the prevention of postoperative recurrence in Crohn's Disease.
- Trial name
- IMURELPOST (NCT00976690)
- Testing
- Azathioprine OR Mesalazine
- Where
- 14 sites in France
- Volunteers
- 83 people
- Sponsor
- Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
Hip Arthropathy, Postoperative Pain, Acute
Pericapsular Nerve Group Block (PENG) for Hip Surgery
This will be a randomized comparison of pericapsular nerve group (PENG) blocks with bupivacaine and a placebo control (PENG blocks with normal saline).
- Conditions
- Hip Arthropathy, Postoperative Pain, Acute, Pain, Postoperative
- Trial name
- NCT05118620
- Testing
- Active bupivacaine 0.375% PENG block
- Where
- United States
- Sponsor
- University of California, San Diego
Knee Osteoarthritis, Vitamin D Deficiency
Prospective, Assessment of Vitamin D and Calcium Supplementation, Improvement of Nutritional Status and Preoperative Rehabilitation in Patients Before Knee Arthroplasty.
Prospective randomized study of 150 patients qualified for knee arthroplasty between 2015 and 2017. Patients were randomized into 3 groups receiving vitamin D and calcium supplementation, increased protein supply and preoperative…
- Conditions
- Knee Osteoarthritis, Vitamin D Deficiency, Pain, Postoperative, Arthropathy of Knee
- Trial name
- NCT04291833
- Testing
- Intervention group 1, Intervention group 2, Control group 0
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Jagiellonian University
Colorectal Cancer, Colo-rectal Cancer
ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial
IMPROVE-IT2 is a randomized multicenter trial comparing the outcomes of ctDNA guided post-operative surveillance and standard-of-care CT-scan surveillance.
- Conditions
- Colorectal Cancer, Colo-rectal Cancer, ctDNA, Gastro-Intestinal Disorder
- Trial name
- NCT04084249
- Testing
- ctDNA-analysis, Intensified Follow-up Schedule
- Where
- 10 sites in Denmark
- Volunteers
- 359 people
- Sponsor
- Claus Lindbjerg Andersen
Lung Transplant; Complications
Bypass vs. Ecmo in Lung Transplantation (BELT)
This study seeks to compare outcomes of 2 different methods of cardiopulmonary support during lung transplant surgeries.
- Trial name
- BELT (NCT03021538)
- Testing
- Extracorporeal Membrane Oxygenation, Cardiopulmonary Bypass
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- The Cleveland Clinic
Postoperative Respiratory Complication
Effect of Preoperative Incentive Spirometer on Postoperative Pulmonary Complications Following Lung Resection
The objective of this study is to demonstrate that inspiratory muscle training with daily use of an incentive spirometer for at least 14 days prior to lung surgery will reduce the risk of post-operative pulmonary complications.
- Trial name
- NCT04732143
- Testing
- Inspiratory muscle training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Atrial Fibrillation, Postoperative Complications
Atrial Dyssynchrony to Predict Arrhythmias in the Postoperative Setting of Cardiovascular Surgery.
This study aims to improve the prediction for developing arrhythmias in the postoperative period of cardiovascular surgery by using non-invasive echocardiographic techniques that are sensitive to detect inter and intra-atrial…
- Trial name
- SAD-POAF (NCT07388108)
- Testing
- Atrial dyssynchrony
- Where
- Argentina
- Volunteers
- 138 people
- Sponsor
- School of Medicine. National University of Cuyo
Postoperative Complication, Respiratory Complications
Real-time Evaluation and Continuous Observation of Vital Signs for Enhanced Recovery: a Study for the Early Identification of Complications in the Surgical Ward Following Surgery in Patients Not Eligible for Intensive Care Admission.
This study aims to evaluate whether continuous vital sign monitoring with wearable devices can help detect postoperative complications in surgical ward earlier than standard hospital monitoring.
- Conditions
- Postoperative Complication, Respiratory Complications, Cardiac Complications
- Trial name
- RECOVER (NCT07729891)
- Testing
- Continuous vital sign monitoring with Portrait Mobile in surgical ward
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma